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Hypercapnia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,952 reports · 184 co-occurring drugs

As of the last recalculation, Hypercapnia appears in 2,952 FAERS reports alongside 184 co-occurring drug terms. The strongest observed disproportionality signal is SEVOFLURANE (PRR 61.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Sevoflurane	71	61.7	62.2
Rocuronium Bromide	65	39.7	40.0
Theophylline	56	35.0	35.2
Theophylline Anhydrous	57	33.0	33.2
Propofol	139	28.1	28.2
0Xygen	154	23.2	23.3
Oxygen	154	23.2	23.3
Bupivacaine	30	22.9	22.9
Midazolam	79	22.7	22.7
Midazolam Hydrochloride	84	22.6	22.7
Norepinephrine	31	20.7	20.7
Acetylcysteine	26	19.6	19.7
Magnesium Sulfate In Water For	35	19.5	19.6
Magnesium Sulfate Heptahydrate	35	19.2	19.2
Magnesium Sulfate	35	19.1	19.2
Norepinephrine Bitartrate	37	18.3	18.4
Fluticasone Furoate	29	17.0	17.1
Cefepime Hydrochloride	38	16.8	16.9
Ipratropium Bromide	80	16.2	16.3
Cefepime	32	15.9	15.9
Methadone Hydrochloride	21	13.8	13.8
Micafungin Sodium	16	13.4	13.4
Oxazepam	38	12.6	12.6
Ampicillin	13	11.1	11.1
Ampicillin Sodium	13	11.1	11.1
Azithromycin	62	11.1	11.1
Methadone	65	10.9	10.9
Azithromycin Monohydrate	62	10.7	10.7
Levodopa	18	10.6	10.6
Piperacillin Sodium And Tazobactam Sodium	29	10.5	10.5
Fentanyl	139	10.4	10.4
Umeclidinium	13	10.3	10.3
Meropenem	45	10.0	10.0
Oseltamivir	11	9.8	9.8
Instalax Polyethylene Glycol 3350	17	9.7	9.7
Mepolizumab	66	9.6	9.6
Polyethylene Glycol 400	17	9.5	9.5
Piperacillin And Tazobactam	17	9.4	9.4
Morphine	93	9.0	9.1
Ganciclovir	13	9.0	9.0
Lubiprostone	12	9.0	9.0
Atazanavir	18	8.9	8.9
Tolvaptan	18	8.8	8.8
Ganciclovir Sodium	13	8.7	8.7
Rabeprazole	27	8.7	8.7
Adrenalinum	50	8.6	8.6
Azithromycin Dihydrate	70	8.6	8.6
Albuterol	138	8.5	8.5
Anti-Itch	78	8.4	8.4
Anti-Pruritic	78	8.4	8.4
Antipruritic (Anti-Itch)	78	8.4	8.4
Cool Relief Gel With Aloe	78	8.4	8.4
Drs. Hydrocortisone	78	8.4	8.4
Hydrocortisone Continuous Spray	78	8.4	8.4
Hydrocortisone Spray	78	8.4	8.4
Anti-Itch Cream	78	8.4	8.4
Hydrocortisone Lotion	78	8.4	8.4
Hydrocortisone Cream 1%	78	8.4	8.4
Hydrocortisone Cream 1/2%	78	8.4	8.4
Hydrocortisone 1%	78	8.4	8.4
Hydrocortisone Cream	78	8.4	8.4
Amikacin	20	8.3	8.3
Cefazolin Sodium	14	8.2	8.2
Haloperidol Lactate	28	8.0	8.0
Nebivolol	18	8.0	8.0
Remdesivir	15	8.0	8.0
Hydrocortisone Acetate	79	7.8	7.9
Haloperidol	26	7.6	7.6
Erythromycin	20	7.6	7.6
Pramipexole	16	7.4	7.4
Ceftriaxone	34	7.4	7.4
Amphotericin B	13	7.3	7.4
Olanzapine Pamoate	41	7.1	7.2
Fentanyl Citrate	18	7.1	7.1
Vancomycin	57	7.1	7.1
Valproic Acid	31	7.0	7.0
Valganciclovir Hydrochloride Powder,	12	7.0	7.0
Febuxostat Tablets 40 Mg	10	7.0	7.0
Febuxostat Tablets 80 Mg	10	7.0	7.0
Ceftriaxone Sodium	37	6.9	6.9
Amphetamine	8	6.8	6.8
Potassium Chloride, Dextrose Monohydrate	87	6.8	6.8
Potassium Chloride Oral	87	6.8	6.8
Potassium Chloride Extended-Release	87	6.8	6.8
Macitentan	65	6.7	6.8
Tiotropium Bromide	126	6.7	6.7
Clobazam	23	6.7	6.7
Clarithromycin	32	6.6	6.6
Lumacaftor And Ivacaftor	8	6.6	6.6
Voriconazole Injection	20	6.5	6.5
Vancomycin Hydrochloride	60	6.5	6.5
Epinephrine	59	6.5	6.5
Lidicaine	44	6.4	6.4
Burn Relief	44	6.4	6.4
Lidocaine Hydrochloride	54	6.4	6.4
Lidocaine Hydrochloride And Epinephrine	44	6.4	6.4
Lidocaine, Menthol	44	6.3	6.3
Selexipag	23	6.3	6.3
Voriconazole	27	6.3	6.3
Metolazone	10	6.3	6.3
Rifampicin	9	6.3	6.3
Dexamethasone Sodium Phosphate	9	6.3	6.3
Cefazolin	8	6.2	6.2
Sildenafil Powder,	31	6.2	6.2
Lidocaine Hydrochloride And Epinephrine Bitartrate	46	6.2	6.2
Piperacillin Sodium,Tazobactam Sodium	23	6.2	6.2
Sodium Bicarbonate	20	6.1	6.1
Sodium Bicarbonate Injection,	20	6.1	6.1
Enoxaparin Sodium	49	6.1	6.1
Mirtazapine	77	6.1	6.1
Lidocaine 4%	46	6.0	6.0
Ketoprofen	11	5.9	5.9
Potassium Chloride	93	5.9	5.9
Bumetanide	22	5.9	5.9
Dextrose	11	5.9	5.9
Atropine Sulfate	9	5.9	5.9
Polyethylene Glycol	9	5.9	5.9
Dextrose Monohydrate	11	5.8	5.8
Sildenafil	47	5.8	5.8
Furosemide	300	5.8	5.8
Lidocaine	47	5.8	5.8
Salmeterol Xinafoate	7	5.7	5.7
Valganciclovir	15	5.6	5.6
Valganciclovir Hydrochloride	15	5.6	5.6
Albuterol Sulfate	221	5.6	5.6
Tranexamic Acid	7	5.6	5.6
Quetiapine Fumarate	23	5.5	5.5
Epoprostenol	10	5.4	5.4
Digoxin	54	5.4	5.4
Fluticasone Propionate And Salmeterol Xinafoate	45	5.3	5.4
Spironolactone	101	5.2	5.2
Tobramycin Sulfate	9	5.1	5.1
Loperamide Hydrochloride And Dimethicone	23	5.1	5.1
Daspone	7	5.1	5.1
Dapsone Gel, 5%	7	5.1	5.1
Diazepam	85	5.0	5.0
Primidone	7	4.9	4.9
Rifampin	10	4.8	4.8
Zonisamide	10	4.8	4.8
Linezolid	20	4.8	4.8
Tobramycin Solution	8	4.7	4.7
Anakinra	11	4.7	4.7
Olanzapine	70	4.7	4.7
Bosentan	33	4.7	4.7
Febuxostat	11	4.6	4.6
Oseltamivir Phosphate	16	4.6	4.6
Pegaspargase	8	4.6	4.6
Daptomycin	6	4.6	4.6
Buspirone Hydrochloride	7	4.5	4.5
Quinapril Hydrochloride	5	4.5	4.5
Tobramycin	15	4.4	4.4
Atovaquone	5	4.4	4.4
Sildenafil Citrate	77	4.4	4.4
Ifosfamide	13	4.3	4.3
Alteplase	9	4.2	4.2
Loperamide Hydrochloride Oral	6	4.1	4.2
Tramadol Hydrochloride	22	4.1	4.1
Morphine Sulfate	66	3.9	3.9
Vigabatrin	8	3.9	3.9
Levetiracetam In Sodium Chloride	42	3.9	3.9
Levetiracetam Oral	42	3.9	3.9
Levetiracetam Injection	42	3.9	3.9
Thiotepa	5	3.7	3.7
Dornase Alfa	10	3.6	3.6
Etoposide	37	3.6	3.6
Riociguat	16	3.5	3.5
Aprepitant	9	3.4	3.4
Umeclidinium Bromide And Vilanterol Trifenatate	8	3.4	3.4
Brinzolamide	4	3.3	3.3
Miconazole Nitrate	4	3.2	3.2
Tadalafil	42	3.0	3.0
Fluticasone Propionate And Salmeterol	17	2.9	2.9
Botulinum Toxin Type A	5	2.8	2.8
Treprostinil	49	2.8	2.8
Palivizumab	6	2.8	2.8
Lapatinib	6	2.7	2.7
Budesonide, Glycopyrrolate, And Formoterol Fumarate	4	2.7	2.7
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	15	2.6	2.6
Emtricitabine And Tenofovir Disoproxil Fumarate	16	2.5	2.5
Ambrisentan	43	2.4	2.4
Durvalumab	5	1.7	1.7
Pirfenidone	10	1.7	1.7
Elexacaftor, Tezacaftor, And Ivacaftor	3	1.7	1.7
Patiromer	3	1.5	1.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.