Reaction

Onychomycosis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,323 reports · 271 co-occurring drugs

As of the last recalculation, Onychomycosis appears in 4,323 FAERS reports alongside 271 co-occurring drug terms. The strongest observed disproportionality signal is PSEUDOEPHEDRINE HYDROCHLORIDE (PRR 229.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Pseudoephedrine Hydrochloride	440	229.4	239.7
Pseudoephedrine Hcl	443	215.6	224.6
Cortisone Acetate	477	209.0	217.4
Desoximetasone	550	159.1	163.8
Botulinum Toxin Type A	364	154.0	158.7
Diclofenac Potassium, Film Coated	247	149.8	154.4
Diclofenac Potassium Tablets	247	149.7	154.2
Minocycline	329	147.0	151.3
Chlorhexidine Gluconate	231	128.5	131.9
Diclofenac Potassium	248	117.2	119.9
Naproxen Sodium Tablet, Coated	255	96.3	98.1
Naproxen Sodium, Coated Tablets	255	96.3	98.1
Naproxen Sodium 220Mg	255	96.2	98.0
Tofacitinib Citrate	228	88.3	89.9
Diclofenac Sodium 1%	540	83.0	84.3
Diclofenac Sodium Topical	540	83.0	84.3
Diclofenac Sodium Topical Gel, 1%	540	82.9	84.1
Thiamine Hydrochloride	178	71.8	72.8
Cetirizine Hydrochloride Allergy	406	71.1	72.1
Cetirizine Hydrochloride Tablets	406	71.1	72.1
Candesartan	452	68.0	68.9
Acetaminophen And Codeine	162	66.5	67.4
Atomoxetine Hydrochloride	274	59.1	59.8
Methylprednisolone Acetate	91	55.9	56.5
Adalimumab-Adaz	537	55.8	56.4
Mirabegron	396	54.1	54.7
Sarilumab	275	53.5	54.0
Tramadol Hydrochloride	381	53.3	53.9
Triamcinolone Acetonide Ointment Usp, 0.05%	244	53.1	53.7
Sulfasalazine	719	52.9	53.4
Terbinafine Hydrochloride	95	52.6	53.2
Adalimumab-Fkjp	451	52.2	52.7
Adalimumab-Aaty	451	51.1	51.6
Mepolizumab	469	50.9	51.3
Erenumab-Aooe	512	50.6	51.1
Golimumab	746	50.4	50.8
Leflunomide	846	48.2	48.5
Hydroxychloroquine	623	46.8	47.2
Isopropyl Alcohol	302	46.2	46.6
Alendronate Sodium	789	45.8	46.2
Tocilizumab	869	45.6	46.0
Diclofenac	667	43.9	44.2
Methylprednisolone Sodium Succinate	376	42.6	43.0
Triamcinolone Acetonide	246	40.6	40.9
Cetirizine	567	40.3	40.6
Alcohol	298	39.6	39.9
Certolizumab Pegol	772	38.4	38.6
Naproxen	546	38.2	38.4
Hydrocortisone Acetate	490	36.5	36.7
Hydrocortisone Sodium Succinate	69	35.9	36.2
Hydroxychloroquine Sulfate	561	33.9	34.1
Anti-Itch	410	32.4	32.6
Anti-Pruritic	410	32.4	32.6
Antipruritic (Anti-Itch)	410	32.4	32.6
Cool Relief Gel With Aloe	410	32.4	32.6
Drs. Hydrocortisone	410	32.4	32.6
Hydrocortisone Continuous Spray	410	32.4	32.6
Hydrocortisone Spray	410	32.4	32.6
Anti-Itch Cream	410	32.4	32.6
Hydrocortisone Lotion	410	32.4	32.6
Hydrocortisone Cream 1%	410	32.4	32.6
Hydrocortisone Cream 1/2%	410	32.4	32.6
Hydrocortisone 1%	410	32.4	32.6
Hydrocortisone Cream	410	32.3	32.5
Cetiirizine	262	31.6	31.8
Abatacept	749	31.3	31.5
Hydrocortisone	478	28.9	29.0
Diclofenac Sodium	702	26.6	26.7
Methylprednisolone	611	24.6	24.7
Antacid	229	24.5	24.6
Azathioprine	398	23.9	24.0
Naproxen Sodium	605	23.5	23.6
Rituximab	841	23.5	23.6
Zinc	115	23.0	23.1
Calcium Carbonate	300	23.0	23.1
Zinc Chloride	115	22.9	23.0
Buprenorphine	400	22.8	22.9
Secukinumab	654	22.8	22.9
Topiramate	400	22.7	22.8
Tofacitinib	716	22.2	22.3
Zinc Gluconate	116	21.9	22.0
Infliximab	797	21.3	21.4
Celecoxib	515	21.2	21.3
Cetirizine Hydrochloride	610	20.6	20.6
Ustekinumab	389	20.0	20.1
Ramipril	438	18.8	18.9
Lamotrigine	456	18.5	18.6
Apremilast	475	17.4	17.5
Vitamin C	305	17.1	17.2
Folic Acid	735	16.9	16.9
Metformin Hydrochloride Tablets	186	16.3	16.3
Metformin Hydrochloride Extended-Release Tablets	186	16.3	16.3
Metformin Hydrochloride Tablet	186	16.3	16.3
Metformin Hydrochloride	186	15.8	15.8
Ascorbic Acid	72	15.1	15.2
Acetaminophen Tablet Extended Release	668	14.7	14.8
Pain Reliever	668	14.7	14.8
Acetaminophen 500Mg	668	14.7	14.8
Alendronate Sodium Tablet	55	14.5	14.5
Tretinoin	24	14.3	14.3
Ranitidine Hydrochloride	156	14.3	14.3
Oxycodone	481	13.8	13.8
Methotrexate	923	13.2	13.2
Methotrexate Sodium	1,020	12.9	12.9
Risedronate Sodium	80	12.6	12.6
Calcium Gluconate	29	11.7	11.7
Itraconazole	27	11.2	11.2
Diphenhydramine Hydrochloride Capsule, Liquid Filled	47	10.7	10.7
Etanercept	1,028	10.5	10.6
Prednisone	866	10.1	10.1
Acetaminophen	770	9.9	9.9
Adalimumab	1,093	9.6	9.6
Magnesium Hydroxide	25	9.0	9.0
Clindamycin	51	8.7	8.8
Doxyclycline Hyclate	30	8.5	8.5
Clindamycin Phosphate	58	8.5	8.5
Tranexamic Acid	14	7.6	7.6
Ergocalciferol	541	7.6	7.6
Tolterodine Tartrate	14	7.5	7.5
Psyllium Husk	15	7.3	7.3
Diltiazem Hydrochloride Extended-Release Tablets	17	7.2	7.2
Ocrelizumab	91	7.2	7.2
Cyclobenzaprine Hydrochloride	13	7.0	7.0
Calcium, Magnesium, Potassium, And Sodium Oxybates	12	6.7	6.7
Candesartan Cilexetil	36	6.6	6.6
Quetiapine Fumarate	40	6.6	6.6
Trazodone Hydrochloride	21	6.5	6.5
Valganciclovir Hydrochloride Powder,	16	6.3	6.3
Basiliximab	15	6.2	6.2
Loratadine And Pseudoephedrine Sulfate	10	6.1	6.1
Ranitidine	235	6.0	6.0
Cyclobenzaprine	60	5.9	5.9
Exemestane	25	5.6	5.7
Cephalexin	25	5.6	5.6
Ketoconazole	20	5.6	5.6
Ketoconazole Foam	17	5.6	5.6
Ketoconazole Cream, 2%	17	5.5	5.5
Baricitinib	11	5.5	5.5
Raloxifene Hydrochloride	16	5.3	5.3
Cetirizine Hcl	10	5.3	5.3
Sulfamethoxazole And Trimethoprim	90	5.2	5.2
Biotin	33	5.1	5.1
Methocarbamol	24	5.1	5.1
Docusate Sodium - Sennosides	34	5.1	5.1
Temazepam	39	5.0	5.0
Magnesium	84	5.0	5.0
Promethazine Hydrochloride	19	4.9	4.9
Methocarbamol Tablets	17	4.9	4.9
Metformin	336	4.8	4.8
Sodium Bicarbonate	23	4.8	4.8
Sodium Bicarbonate Injection,	23	4.8	4.8
Diltiazem Hydrochloride	34	4.8	4.8
Clotrimazole	12	4.7	4.7
Cyanocobalamin	32	4.7	4.7
Calcium	141	4.7	4.7
Clobetasol Propionate Ointment Usp, 0.05%	10	4.7	4.7
Clobetasol Propionate	10	4.7	4.7
Ibrutinib	77	4.7	4.7
Standardized Senna Concentrate	12	4.6	4.6
Drs. Clotrimazole	11	4.6	4.6
Family Wellness Clotrimazole	11	4.6	4.6
Clotrimazole Topical	11	4.6	4.6
Losartan Potassium And Hydrochlorothiazide	11	4.6	4.6
Olanzapine Pamoate	37	4.4	4.4
Erythromycin	17	4.4	4.4
Valganciclovir	17	4.4	4.4
Valganciclovir Hydrochloride	17	4.4	4.4
Doxycycline	61	4.4	4.4
Doxycycline Hyclate	60	4.3	4.3
Meclizine Hcl 12.5Mg	12	4.2	4.3
Meclizine Hcl 25Mg	12	4.2	4.3
Meclizine Hcl 12.5 Mg	12	4.2	4.2
Meclizine Hcl 25 Mg	12	4.2	4.2
Diphenoxylate Hydrochloride And Atropine Sulfate	12	4.2	4.2
Progesterone	20	4.2	4.2
Hyoscyamine Sulfate	8	4.2	4.2
Amlodipine Besylate And Benazepril Hydrochloride	8	4.2	4.2
Fexofenadine Hcl	8	4.2	4.2
Anakinra	14	4.1	4.1
Carisoprodol	16	4.0	4.1
Cladribine	8	4.0	4.0
Fluticasone Propionate Nasal	25	4.0	4.0
Erlotinib	8	4.0	4.0
Rifampin	12	4.0	4.0
Meloxicam	47	3.9	3.9
Liothyronine Sodium	7	3.9	3.9
Meclizine	13	3.8	3.8
Rizatriptan Benzoate	8	3.8	3.8
Testosterone Cypionate	7	3.8	3.8
Azithromycin	31	3.7	3.7
Ziprasidone Mesylate	11	3.7	3.7
Zolpidem Tartrate	100	3.6	3.6
Azithromycin Monohydrate	31	3.6	3.6
Sildenafil	43	3.6	3.6
Glyburide	18	3.6	3.6
Fish Oil	66	3.6	3.6
Indapamide	13	3.5	3.5
Human Insulin	9	3.5	3.5
Hydrochlorothiazide	103	3.5	3.5
Letrozole	44	3.5	3.5
Meclizine Hydrochloride	14	3.4	3.5
Armodafinil	15	3.4	3.4
Bimekizumab	15	3.4	3.4
Lamotirigine	50	3.4	3.4
Lamotrigine Extended-Release	50	3.4	3.4
Lamotrigine Chewable Dispersible	50	3.4	3.4
Osimertinib	22	3.3	3.3
Modafinil	22	3.3	3.3
Erythropoietin	14	3.3	3.3
Sodium Oxybate	44	3.2	3.2
Gefitinib	6	3.2	3.2
Timolol	8	3.2	3.2
Memantine	9	3.2	3.2
Memantine Hydrochloride	9	3.2	3.2
Fluticasone Propionate	84	3.2	3.2
Losartan Potassium	51	3.1	3.1
Sildenafil Powder,	23	3.1	3.1
Erlotinib Hydrochloride	8	3.1	3.1
Finasteride	38	3.1	3.1
Dorzolamide Hydrochloride And Timolol Maleate	5	3.0	3.0
Upadacitinib	51	3.0	3.0
Nebivolol	10	3.0	3.0
Efavirenz	7	3.0	3.0
Pertuzumab	17	3.0	3.0
Ziprasidone	11	3.0	3.0
Nebivolol Hydrochloride	21	3.0	3.0
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	21	2.9	2.9
Bleomycin Sulfate	6	2.8	2.8
Onabotulinumtoxina	44	2.8	2.8
Brimonidine Tartrate	10	2.7	2.7
Multivitamin	28	2.7	2.7
Azelastine	10	2.7	2.7
Eszopiclone	14	2.7	2.7
Oxycodone Hydrochloride And Acetaminophen	54	2.7	2.7
Thalidomide	20	2.6	2.6
Niraparib	12	2.6	2.6
Oxycodone Hydrochloride	113	2.5	2.5
Glipizide	32	2.5	2.5
Ibuprofen Tablets, Coated	22	2.5	2.5
Lapatinib	8	2.5	2.5
Ibuprofen Sodium	22	2.5	2.5
Pioglitazone	22	2.5	2.5
Metformin Hcl	28	2.4	2.4
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	21	2.4	2.4
Avapritinib	6	2.4	2.4
Sildenafil Citrate	62	2.4	2.4
Ruxolitinib	34	2.3	2.3
Nilotinib	14	2.3	2.3
Ado-Trastuzumab Emtansine	4	2.3	2.3
Oxycodone And Acetaminophen	11	2.3	2.3
Miconazole Nitrate	4	2.2	2.2
Darbepoetin Alfa	24	2.2	2.2
Trastuzumab	30	2.1	2.1
Naproxen Sodium Tablet	22	2.0	2.0
Fexofenadine Hydrochloride	9	2.0	2.0
Teriflunomide	18	1.9	1.9
Fingolimod Hcl	33	1.8	1.8
Medroxyprogesterone Acetate	19	1.8	1.8
Dalfampridine	27	1.8	1.8
Risankizumab-Rzaa	28	1.7	1.7
Cannabidiol	8	1.6	1.6
Rucaparib	3	1.6	1.6
Canagliflozin	10	1.6	1.6
Ixazomib	9	1.5	1.5
Abemaciclib	6	1.4	1.4
Diroximel Fumarate	3	1.2	1.2
Guselkumab	9	1.2	1.2
Relugolix	5	1.0	1.0
Salicylic Acid	10	0.9	0.9
Dupilumab	91	0.9	0.9
Pomalidomide	19	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.