Reaction

Synovial Cyst reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,583 reports · 224 co-occurring drugs

As of the last recalculation, Synovial Cyst appears in 4,583 FAERS reports alongside 224 co-occurring drug terms. The strongest observed disproportionality signal is METHYLPREDNISOLONE ACETATE (PRR 116.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Methylprednisolone Acetate	196	116.1	119.0
Meloxicam	299	24.9	25.1
Esomeprazole Magnesium Capsule, Delayed Release	75	23.8	24.0
Esomeprazole Magnesium Delayed Release Capsules	75	23.8	24.0
Esomeprazole Magnesium Dihydrate	75	23.7	23.9
Leflunomide	421	20.0	20.1
Alendronate Sodium	397	19.5	19.5
Trimethoprim	46	17.9	18.0
Hydroxychloroquine Sulfate	322	17.2	17.2
Sulfasalazine	275	16.9	17.0
Diclofenac	263	14.6	14.7
Tocilizumab	320	13.6	13.7
Tofacitinib Citrate	39	13.6	13.7
Amitriptyline Hydrochloride	52	13.6	13.6
Desloratadine	31	13.2	13.2
Hydroxychloroquine	196	12.4	12.4
Clotrimazole	31	11.5	11.6
Risedronate Sodium	76	11.3	11.3
Drs. Clotrimazole	28	11.1	11.1
Family Wellness Clotrimazole	28	11.1	11.1
Clotrimazole Topical	28	11.1	11.1
Methotrexate	844	10.9	11.0
Methotrexate Sodium	949	10.9	10.9
Naproxen	178	10.7	10.7
Rifampin	34	10.6	10.7
Methocarbamol	52	10.5	10.5
Abatacept	292	10.2	10.2
Sucralfate Oral	31	10.0	10.0
Sucralfate Oral Suspension	31	9.9	10.0
Diphenhydramine Hydrochloride Capsule, Liquid Filled	45	9.7	9.7
Esomeprazole	128	9.6	9.6
Diclofenac Sodium	299	9.6	9.6
Ketoconazole	34	9.0	9.0
Chlorhexidine Gluconate	18	9.0	9.0
Adalimumab	1,091	8.9	8.9
Tofacitinib	327	8.6	8.6
Celecoxib	235	8.5	8.5
Naproxen Sodium Tablet, Coated	25	8.4	8.4
Naproxen Sodium, Coated Tablets	25	8.4	8.4
Naproxen Sodium 220Mg	25	8.4	8.4
Adalimumab-Fkjp	83	8.3	8.3
Cimetidine	17	8.0	8.1
Anakinra	28	7.7	7.7
Cephalexin	36	7.6	7.6
Adalimumab-Aaty	78	7.6	7.6
Adalimumab-Adaz	86	7.5	7.5
Ascorbic Acid	38	7.5	7.5
Folic Acid	376	7.4	7.4
Sucralfate	38	7.3	7.3
Cefuroxime	18	7.2	7.2
Baricitinib	15	7.1	7.1
Pantoprazole Sodium In 0.9% Sodium Chloride	95	7.1	7.1
Pantoprazole Sodium Injection	95	7.1	7.1
Daspone	15	7.0	7.0
Dapsone Gel, 5%	15	7.0	7.0
Indomethacin	20	6.9	6.9
Dimenhydrinate	16	6.8	6.8
Naproxen Sodium	206	6.8	6.8
Theophylline	17	6.7	6.7
Theophylline Anhydrous	18	6.6	6.6
Dapsone	15	6.4	6.4
Octreotide Acetate	42	6.3	6.3
Azathioprine	119	6.3	6.3
Diclofenac Sodium 1%	48	6.2	6.2
Diclofenac Sodium Topical	48	6.2	6.2
Diclofenac Sodium Topical Gel, 1%	48	6.1	6.2
Dexlansoprazole	55	6.0	6.1
Exemestane	28	6.0	6.0
Diclofenac Potassium, Film Coated	11	5.9	6.0
Diclofenac Potassium Tablets	11	5.9	6.0
Hydrocortisone Sodium Succinate	12	5.8	5.8
Golimumab	106	5.7	5.7
Alendronate Sodium Tablet	23	5.7	5.7
Tolterodine Tartrate	11	5.6	5.6
Anastrozole Tablets	26	5.5	5.5
Ribociclib	38	5.5	5.5
Prednisone	549	5.5	5.5
Anastrozole	44	5.5	5.5
Etanercept	634	5.4	5.4
Dronedarone	12	5.4	5.4
Oxycodone And Acetaminophen Tablets	14	5.3	5.4
Metronidazole	73	5.3	5.3
Rituximab	232	5.2	5.2
Loratadine And Pseudoephedrine Sulfate	9	5.1	5.2
Cyanocobalamin	37	5.1	5.1
Methylprednisolone Sodium Succinate	52	5.1	5.1
Amoxicillin	85	5.1	5.1
Cetirizine Hydrochloride Allergy	34	5.1	5.1
Cetirizine Hydrochloride Tablets	34	5.1	5.1
Vitamin E	35	5.1	5.1
Upadacitinib	89	5.0	5.0
Infliximab-Dyyb	32	5.0	5.0
Etonogestrel And Ethinyl Estradiol	24	4.9	4.9
Methocarbamol Tablets	18	4.9	4.9
Human Immunoglobulin G	22	4.9	4.9
Ibuprofen Tablets, Coated	45	4.8	4.8
Ibuprofen Sodium	45	4.8	4.8
Cortisone Acetate	13	4.8	4.8
Letrozole	64	4.8	4.8
Methylprednisolone	141	4.7	4.8
Calcium	150	4.7	4.7
Rosuvastatin Calcium	29	4.7	4.7
Doxepin Hydrochloride	13	4.7	4.7
Mupirocin Calcium	14	4.6	4.6
Diclofenac Potassium	11	4.6	4.6
Antacid	48	4.6	4.6
Sulfamethoxazole And Trimethoprim	84	4.6	4.6
Carisoprodol	19	4.5	4.5
Clindamycin	28	4.5	4.5
Certolizumab Pegol	113	4.5	4.5
Hyoscyamine Sulfate	9	4.5	4.5
Pantoprazole Sodium	142	4.5	4.5
Amlodipine Besylate And Benazepril Hydrochloride	9	4.4	4.4
Biotin	30	4.4	4.4
Mupirocin	13	4.4	4.4
Erythromycin	18	4.4	4.4
Raloxifene Hydrochloride	14	4.4	4.4
Telmisartan	17	4.3	4.3
Ibuprofen And Diphenhydramine Citrate	22	4.3	4.3
Lisdexamfetamine Dimesylate	31	4.3	4.3
Thyroid, Porcine	10	4.3	4.3
Cladribine	9	4.3	4.3
Docusate Sodium - Sennosides	30	4.2	4.3
Quinine	8	4.2	4.2
Canakinumab	10	4.2	4.2
Ezetimibe And Simvastatin	14	4.2	4.2
Psyllium Husk	9	4.1	4.1
Fenofibrate	32	4.1	4.1
Clindamycin Phosphate	30	4.1	4.1
Calcium Carbonate	60	4.1	4.1
Fulvestrant	29	4.0	4.0
Esomeprazole Magnesium	197	3.9	4.0
Losartan Potassium And Hydrochlorothiazide	10	3.9	3.9
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	26	3.9	3.9
Letrozole Tablets	41	3.9	3.9
Tizanidine	20	3.8	3.8
Tizanidine Hydrochloride	15	3.8	3.8
Ciprofolxacin	59	3.8	3.8
Ciprofloxacin Tablets	59	3.8	3.8
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	130	3.8	3.8
Ergocalciferol	303	3.8	3.8
Naltrexone Hydrochloride And Bupropion Hydrochloride	7	3.7	3.7
Pantoprazole	201	3.7	3.7
Torsemide	27	3.7	3.7
Iron	54	3.7	3.7
Cetirizine	62	3.7	3.7
Irbesartan	35	3.6	3.6
Zoledronic Acid	31	3.5	3.5
Ibuprofen	203	3.5	3.5
Trazodone Hydrochloride	12	3.5	3.5
Pregabalin	201	3.5	3.5
Infliximab	162	3.5	3.5
Valsartan Oral	41	3.4	3.5
Fexofenadine Hcl	7	3.4	3.4
Ibuprofen Capsule	146	3.4	3.4
Ibuprofen Tablet, Film Coated	146	3.4	3.4
Ibupfrofen	146	3.4	3.4
Ibuprofen Tablets Usp, 200Mg	146	3.4	3.4
Ibuprofen Oral	146	3.4	3.4
Ibuprofen Capsules 200 Mg	146	3.4	3.4
Ibuprofen 200 Mg	146	3.4	3.4
Ibuprofen 200Mg	146	3.4	3.4
Ranitidine Hydrochloride	40	3.4	3.4
Fish Oil	66	3.3	3.4
Valsartan	76	3.3	3.3
Erythropoietin	15	3.3	3.3
Famotidine	83	3.2	3.3
Timolol Maleate	7	3.2	3.2
Asfotase Alfa	7	3.2	3.2
Secukinumab	111	3.2	3.2
Rabeprazole Sodium	19	3.2	3.2
Estradiol Gel 0.1%	31	3.1	3.1
Rizatriptan Benzoate	7	3.1	3.1
Estradiol Transdermal	31	3.1	3.1
Modafinil	22	3.1	3.1
Cetiirizine	28	3.0	3.0
Cetirizine Hydrochloride	107	3.0	3.0
Ezetimibe	48	2.9	2.9
Triamcinolone Acetonide Ointment Usp, 0.05%	15	2.9	2.9
Estradiol	55	2.9	2.9
Quinapril Hydrochloride	5	2.9	2.9
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	13	2.9	2.9
Naproxen Sodium, Pseudoephedrine Hydrochloride	13	2.9	2.9
Desoximetasone	12	2.9	2.9
Ibrutinib	50	2.8	2.8
Oxycodone And Acetaminophen	14	2.7	2.7
Estrogens, Conjugated	35	2.7	2.7
Conjugated Estrogens	34	2.7	2.7
Levocetirizine Dihydrochloride	14	2.7	2.7
Ranitidine	113	2.6	2.6
Sarilumab	15	2.6	2.6
Fexofenadine Hydrochloride	12	2.5	2.5
Oxycodone Hydrochloride And Acetaminophen	53	2.5	2.5
Armodafinil	11	2.4	2.4
Risankizumab-Rzaa	42	2.3	2.3
Conjugated Estrogens And Medroxyprogesterone Acetate	12	2.3	2.3
Acetaminophen, Aspirin, And Caffeine	10	2.2	2.2
Icosapent Ethyl	4	2.1	2.1
Mirabegron	18	2.1	2.1
Mepolizumab	23	2.1	2.1
Bosutinib	4	2.0	2.0
Emtricitabine And Tenofovir Alafenamide	5	2.0	2.0
Eltrombopag Olamine	10	2.0	2.0
Acetaminophen, Aspirin (Nsaid) And Caffeine	7	1.9	1.9
Denosumab	79	1.8	1.8
Brentuximab Vedotin	4	1.8	1.8
Cannabidiol	9	1.7	1.7
Teriflunomide	17	1.7	1.7
Interferon Beta-1A	72	1.7	1.7
Pseudoephedrine Hcl	4	1.6	1.6
Naproxen Sodium Tablet	19	1.6	1.6
Ocrelizumab	22	1.6	1.6
Ruxolitinib	25	1.6	1.6
Sodium Oxybate	23	1.6	1.6
Abaloparatide	10	1.5	1.5
Avapritinib	4	1.5	1.5
Ixekizumab	12	1.5	1.5
Pseudoephedrine Hydrochloride	3	1.3	1.3
Ledipasvir And Sofosbuvir	5	1.2	1.2
Emicizumab	3	1.1	1.1
Apremilast	32	1.0	1.0
Galcanezumab-Gnlm	5	0.7	0.7
Valbenazine	3	0.5	0.5
Salicylic Acid	4	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.