Reaction

Blood Pressure Diastolic Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,575 reports · 265 co-occurring drugs

As of the last recalculation, Blood Pressure Diastolic Increased appears in 4,575 FAERS reports alongside 265 co-occurring drug terms. The strongest observed disproportionality signal is INFLIXIMAB-DYYB (PRR 63.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Infliximab-Dyyb	376	63.7	64.5
Octreotide Acetate	366	59.0	59.7
Diphenhydramine Hydrochloride Capsule, Liquid Filled	191	42.4	42.8
Methylprednisolone Sodium Succinate	330	34.8	35.0
Dimenhydrinate	58	25.1	25.2
Risedronate Sodium	158	23.9	24.0
Diphenhydramine Hydrochloride	714	23.0	23.1
Tocilizumab	507	22.6	22.7
Methylprednisolone	527	19.5	19.5
Diphenhydramine	251	19.1	19.1
Desoximetasone	68	16.5	16.5
Dalteparin Sodium	37	16.0	16.1
Rosuvastatin Calcium	93	15.3	15.4
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	460	14.4	14.5
Hydrocortisone Sodium Succinate	29	14.1	14.2
Acetaminophen Tablet Extended Release	673	13.9	13.9
Pain Reliever	673	13.9	13.9
Acetaminophen 500Mg	673	13.9	13.9
Ciclesonide	41	13.8	13.8
Rituximab	536	12.9	13.0
Acetaminophen	974	12.3	12.3
Niraparib	58	12.0	12.1
Hydroxychloroquine Sulfate	220	11.5	11.5
Prednisone	1,012	11.5	11.5
Sulfasalazine	186	11.2	11.3
Diphenhydramine Hcl	27	11.1	11.1
Methadone Hydrochloride	26	11.0	11.0
Naproxen	175	10.5	10.5
Indomethacin	30	10.4	10.4
Standardized Senna Concentrate	28	10.2	10.2
Rabeprazole	47	9.7	9.8
Hydrocortisone	182	9.6	9.6
Calcium	292	9.5	9.5
Cetirizine Hydrochloride Allergy	62	9.4	9.4
Cetirizine Hydrochloride Tablets	62	9.4	9.4
Folic Acid	465	9.3	9.3
Azathioprine	170	9.1	9.1
Infliximab	385	8.7	8.7
Loperamide Hydrochloride And Dimethicone	60	8.6	8.6
Naltrexone Hydrochloride And Bupropion Hydrochloride	16	8.6	8.6
Dexlansoprazole	77	8.5	8.5
Anti-Itch	122	8.5	8.5
Anti-Pruritic	122	8.5	8.5
Antipruritic (Anti-Itch)	122	8.5	8.5
Cool Relief Gel With Aloe	122	8.5	8.5
Drs. Hydrocortisone	122	8.5	8.5
Hydrocortisone Continuous Spray	122	8.5	8.5
Hydrocortisone Spray	122	8.5	8.5
Anti-Itch Cream	122	8.5	8.5
Hydrocortisone Lotion	122	8.5	8.5
Hydrocortisone Cream 1%	122	8.5	8.5
Hydrocortisone Cream 1/2%	122	8.5	8.5
Hydrocortisone 1%	122	8.5	8.5
Hydrocortisone Cream	122	8.4	8.4
Pantoprazole Sodium In 0.9% Sodium Chloride	109	8.2	8.2
Pantoprazole Sodium Injection	109	8.2	8.2
Hydrocortisone Acetate	127	8.1	8.2
Lanreotide Acetate	14	8.1	8.2
Methotrexate	634	7.8	7.8
Sucralfate Oral	24	7.7	7.7
Sucralfate Oral Suspension	24	7.7	7.7
Mesalamine	92	7.6	7.6
Methotrexate Sodium	691	7.4	7.5
Leflunomide	162	7.3	7.3
Mometasone	29	7.2	7.2
Cyclobenzaprine Hydrochloride	14	7.1	7.1
Lenvatinib	49	6.9	6.9
Oxazepam	32	6.8	6.8
Droxidopa	32	6.8	6.8
Tranexamic Acid	13	6.7	6.7
Nifedipine	68	6.6	6.6
Tofacitinib Citrate	19	6.6	6.6
Progesterone	33	6.6	6.6
Cetirizine	109	6.5	6.5
Temozolomide	30	6.5	6.5
Clindamycin Phosphate	47	6.5	6.5
Omalizumab	117	6.4	6.4
Loperamide Hydrochloride	62	6.4	6.4
Extended Phenytoin Sodium	23	6.3	6.3
Amlodipine Besylate And Valsartan	15	6.2	6.2
Morphine	99	6.1	6.2
Celecoxib	170	6.1	6.1
Naproxen Sodium	184	6.1	6.1
Ampicillin	11	6.1	6.1
Ampicillin Sodium	11	6.1	6.1
Irbesartan	58	6.0	6.0
Clindamycin	37	6.0	6.0
Ibuprofen Tablets, Coated	55	5.9	6.0
Ibuprofen Sodium	55	5.9	5.9
Pantoprazole	303	5.8	5.8
Candesartan	44	5.7	5.7
Antacid	58	5.6	5.6
Mometasone Furoate	50	5.5	5.5
Cyclobenzaprine	59	5.4	5.4
Polyethylene Glycol 400	15	5.4	5.4
Ramipril	142	5.4	5.4
Cholestyramine	14	5.3	5.3
Venlafaxine	81	5.2	5.2
Moxifloxacin	16	5.2	5.2
Alendronate Sodium Tablet	21	5.2	5.2
Atovaquone	9	5.1	5.1
Iron	72	5.0	5.0
Doxepin	11	4.9	5.0
Cetiirizine	45	4.9	4.9
Cyanocobalamin	35	4.9	4.9
Telmisartan	19	4.9	4.9
Fluticasone Furoate And Vilanterol Trifenatate	38	4.8	4.8
Hydroxychloroquine	78	4.8	4.8
Hydrochlorothiazide	149	4.8	4.8
Instalax Polyethylene Glycol 3350	13	4.8	4.8
Magnesium	85	4.8	4.8
Sucralfate	25	4.8	4.8
Doxepin Hydrochloride	13	4.7	4.7
Candesartan Cilexetil	27	4.7	4.7
Cephalexin	22	4.6	4.6
Quinapril Hydrochloride	8	4.6	4.6
Cannabidiol	23	4.5	4.5
Amlodipine Besylate	141	4.5	4.5
Abatacept	133	4.5	4.5
Clotrimazole	12	4.5	4.5
Diclofenac	83	4.4	4.4
Erythromycin	18	4.4	4.4
Drs. Clotrimazole	11	4.3	4.3
Family Wellness Clotrimazole	11	4.3	4.3
Quetiapine Fumarate	28	4.3	4.3
Clotrimazole Topical	11	4.3	4.3
Vitamin C	86	4.3	4.3
Valsartan	98	4.3	4.3
Moxifloxacin Hydrochloride	19	4.3	4.3
Docusate Sodium - Sennosides	30	4.3	4.3
Mepolizumab	46	4.2	4.2
Calcium Carbonate	62	4.2	4.2
Mycophenolate Mofetil	124	4.2	4.2
Mycophenolate Mofetil Hydrochloride	124	4.2	4.2
Vedolizumab	79	4.2	4.2
Esomeprazole	57	4.2	4.2
Levothyroxine Sodium	275	4.2	4.2
Calcium Gluconate	11	4.2	4.2
Amoxicillin	69	4.2	4.2
Everolimus	46	4.1	4.1
Citalopram Hydrobromide	96	4.1	4.1
Valsartan Oral	49	4.1	4.1
Ibuprofen And Diphenhydramine Citrate	21	4.1	4.1
Cortisone Acetate	11	4.1	4.1
Amlodipine	231	4.1	4.1
Cabozantinib	42	4.0	4.0
Pseudoephedrine Hydrochloride	9	4.0	4.0
Axitinib	17	4.0	4.0
Sildenafil Powder,	30	3.9	3.9
Rabeprazole Sodium	23	3.9	3.9
Desloratadine	9	3.8	3.8
Biotin	26	3.8	3.8
Budesonide And Formoterol Fumarate Dihydrate	80	3.8	3.8
Venlafaxine Hydrochloride	108	3.8	3.8
Fluticasone Furoate	10	3.8	3.8
Labetalol	11	3.8	3.8
Linagliptin	15	3.8	3.8
Fluticasone Propionate And Salmeterol Xinafoate	49	3.7	3.7
Lorazepam	144	3.7	3.7
Pseudoephedrine Hcl	9	3.7	3.7
Montelukast Sodium	98	3.7	3.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	7	3.7	3.7
Valsartan And Hydrochlorothiazide	11	3.7	3.7
Pantoprazole Sodium	118	3.7	3.7
Psyllium Husk	8	3.7	3.7
Cetirizine Hydrochloride	130	3.7	3.7
Cyclosporine	88	3.6	3.7
Citalopram	107	3.6	3.6
Hydromorphone Hydrochloride	72	3.6	3.6
Felodipine Extended-Release Tablets	9	3.6	3.6
Felodipine	9	3.6	3.6
Indapamide	14	3.6	3.6
Sulfamethoxazole And Trimethoprim	65	3.5	3.5
Bisoprolol Fumarate	104	3.5	3.5
Fluconazole	54	3.5	3.5
Dicyclomine Hydrochloride	11	3.5	3.5
Granisetron Hydrochloride	8	3.5	3.5
Granisetron	8	3.5	3.5
Oseltamivir	6	3.4	3.4
Methylphenidate Hydrochloride	44	3.4	3.4
Diclofenac Sodium	109	3.4	3.4
Atorvastatin Calcium, Film Coated	51	3.3	3.3
Clonidine	37	3.3	3.3
Daspone	7	3.3	3.3
Dapsone Gel, 5%	7	3.3	3.3
Atomoxetine Hydrochloride	17	3.3	3.3
Pregabalin	186	3.2	3.2
Rosuvastatin	140	3.2	3.2
Valganciclovir	13	3.1	3.1
Valganciclovir Hydrochloride	13	3.1	3.1
Regorafenib	8	3.1	3.1
Losartan Potassium And Hydrochlorothiazide	8	3.1	3.1
Itraconazole	8	3.1	3.1
Colchicine	18	3.1	3.1
Metoprolol Tartrate Injection	127	3.1	3.1
Ibuprofen	180	3.1	3.1
Etonogestrel And Ethinyl Estradiol	15	3.1	3.1
Tramadol Hydrochloride	25	3.0	3.0
Sildenafil	38	3.0	3.0
Sitagliptin	47	3.0	3.0
Dapsone	7	3.0	3.0
Cetirizine Hcl	6	3.0	3.0
Metformin Er 500 Mg	191	3.0	3.0
Metformin Er 750 Mg	191	3.0	3.0
Diclofenac Potassium	7	3.0	3.0
Bupropion Hydrochloride	63	2.9	2.9
Mercaptopurine	11	2.9	2.9
Metoprolol Tartrate	168	2.9	2.9
Metoprolol	154	2.8	2.8
Bevacizumab	75	2.8	2.8
Chlorthalidone	7	2.7	2.7
Minocycline	7	2.7	2.7
Metformin	208	2.7	2.7
Voclosporin	5	2.6	2.6
Piperacillin Sodium,Tazobactam Sodium	15	2.6	2.6
Desvenlafaxine Succinate	15	2.5	2.5
Oxybutynin	16	2.5	2.5
Methoxy Polyethylene Glycol-Epoetin Beta	6	2.5	2.5
Medroxyprogesterone Acetate	27	2.5	2.5
Prochlorperazine Maleate	5	2.5	2.5
Carboxymethylcellulose Sodium	5	2.4	2.4
Iron Sucrose	5	2.4	2.4
Lisdexamfetamine Dimesylate	17	2.3	2.3
Pertuzumab	14	2.3	2.3
Esketamine Hydrochloride	9	2.3	2.3
Morphine Sulfate	60	2.3	2.3
Dutasteride	4	2.2	2.2
Obinutuzumab	8	2.2	2.2
Pazopanib Hydrochloride	13	2.2	2.2
Dofetilide	5	2.2	2.2
Oxycodone And Acetaminophen	11	2.2	2.2
Ticagrelor	15	2.1	2.1
Methadone	20	2.1	2.1
Fingolimod Hcl	40	2.1	2.1
Trastuzumab	31	2.1	2.1
Oseltamivir Phosphate	11	2.1	2.1
Methylphenidate	13	2.0	2.0
Umeclidinium	4	2.0	2.0
Tofacitinib	81	2.0	2.0
Belimumab	14	2.0	2.0
Sacubitril And Valsartan	49	1.9	1.9
Linaclotide	11	1.9	1.9
Sunitinib Malate	15	1.7	1.7
Pembrolizumab	39	1.7	1.7
Canakinumab	4	1.7	1.7
Iohexol	3	1.6	1.6
Ozanimod Hydrochloride	3	1.6	1.6
Secukinumab	57	1.6	1.6
Teriflunomide	16	1.6	1.6
Benralizumab	7	1.6	1.6
Fremanezumab-Vfrm	4	1.6	1.6
Ustekinumab	35	1.6	1.6
Alteplase	5	1.5	1.5
Certolizumab Pegol	38	1.5	1.5
Ranitidine	64	1.5	1.5
Rimegepant Sulfate	4	1.4	1.4
Ranitidine Hydrochloride	17	1.4	1.4
Denosumab	61	1.4	1.4
Canagliflozin	9	1.4	1.4
Budesonide, Glycopyrrolate, And Formoterol Fumarate	3	1.3	1.3
Abaloparatide	7	1.1	1.1
Relugolix	5	1.0	1.0
Dulaglutide	15	0.8	0.8
Tirzepatide	23	0.6	0.6
Nirmatrelvir And Ritonavir	7	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.