Reaction

Angina Unstable reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,473 reports · 281 co-occurring drugs

As of the last recalculation, Angina Unstable appears in 6,473 FAERS reports alongside 281 co-occurring drug terms. The strongest observed disproportionality signal is TICAGRELOR (PRR 27.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ticagrelor	258	27.0	27.3
Nitroglycerin	417	26.7	26.9
Prasugrel Hydrochloride	67	21.4	21.6
Isosorbide Dinitrate	114	19.1	19.2
Isosorbide Mononitrate	107	16.9	16.9
Clopidogrel	820	15.1	15.1
Ezetimibe	247	11.0	11.0
Amlodipine Besylate And Benazepril Hydrochloride	31	10.8	10.9
Enalapril Maleate	81	10.6	10.7
Clopidogrel Bisulfate	319	10.5	10.5
Aspirin 81 Mg	1,326	10.2	10.2
Aspirin 325 Mg	1,324	10.2	10.2
Aspirin	1,372	10.1	10.2
Captopril	30	10.1	10.1
Diltiazem Hydrochloride	103	9.7	9.7
Ranolazine	29	9.0	9.0
Gemfibrozil	41	8.7	8.8
Nilotinib	78	8.6	8.6
Digoxin	184	8.5	8.5
Ezetimibe And Simvastatin	39	8.3	8.3
Insulin	140	8.2	8.2
Glyburide	61	8.2	8.2
Niacin	29	8.1	8.1
Atorvastatin Calcium	524	7.3	7.3
Inclisiran	18	7.2	7.2
Atenolol	288	7.2	7.2
Testosterone Cypionate	20	7.2	7.2
Meclizine Hcl 12.5Mg	30	7.1	7.1
Meclizine Hcl 25Mg	30	7.1	7.1
Meclizine Hcl 12.5 Mg	30	7.1	7.1
Meclizine Hcl 25 Mg	30	7.1	7.1
Metoprolol Tartrate	543	6.9	6.9
Felodipine Extended-Release Tablets	24	6.8	6.8
Felodipine	24	6.8	6.8
Metoprolol Succinate	176	6.7	6.7
Losartan Potassium And Hydrochlorothiazide	24	6.7	6.7
Rabeprazole Sodium	56	6.7	6.7
Enalapril	113	6.6	6.6
Indapamide	36	6.5	6.5
Amlodipine Besylate And Valsartan	22	6.4	6.4
Meclizine	32	6.3	6.3
Pitavastatin Calcium	20	6.3	6.3
Terazosin Hydrochloride	17	6.2	6.2
Indomethacin	25	6.1	6.1
Metoroprolol Tartrate	122	6.0	6.1
Rosuvastatin	366	6.0	6.0
Losartan Potassium	143	5.9	5.9
Vitamin E	56	5.8	5.8
Cyclobenzaprine Hydrochloride	16	5.7	5.7
Amlodipine Besylate	253	5.7	5.7
Carvedilol	234	5.7	5.7
Valsartan And Hydrochlorothiazide	24	5.7	5.7
Lisinopril And Hydrochlorothiazide	18	5.7	5.7
Simvastatin	414	5.6	5.6
Salmeterol Xinafoate	15	5.6	5.6
Metoprolol	415	5.5	5.5
Bisoprolol Fumarate	226	5.5	5.5
Nifedipine	79	5.4	5.4
Spironolactone	229	5.4	5.4
Meclizine Hydrochloride	32	5.3	5.3
Ipratropium Bromide	58	5.3	5.3
Meperidine Hydrochloride	15	5.2	5.3
Metoprolol Tartrate Injection	295	5.2	5.2
Human Insulin	20	5.2	5.2
Alirocumab	40	5.2	5.2
Glipizide	96	5.1	5.1
Metoprolol Succinate Er Tablets	98	5.1	5.1
Theophylline	18	5.0	5.1
Candesartan Cilexetil	41	5.0	5.0
Eplerenone	20	5.0	5.0
Valsartan	161	5.0	5.0
Tolterodine Tartrate	14	5.0	5.0
Paricalcitol	22	5.0	5.0
Metformin Hcl	85	5.0	5.0
Theophylline Anhydrous	19	4.9	4.9
Quinapril Hydrochloride	12	4.9	4.9
Epoetin Alfa	18	4.9	4.9
Furosemide	567	4.9	4.9
Pioglitazone	65	4.9	4.9
Ramipril	182	4.8	4.8
Diltiazem Hydrochloride Extended-Release Tablets	17	4.8	4.8
Cephalexin	32	4.8	4.8
Rosuvastatin Calcium	41	4.7	4.7
Cimetidine	14	4.7	4.7
Metolazone	16	4.6	4.6
Trazodone Hydrochloride	22	4.5	4.5
Atorvastatin Calcium, Film Coated	97	4.5	4.5
Darunavir	21	4.5	4.5
Febuxostat Tablets 40 Mg	14	4.4	4.4
Febuxostat Tablets 80 Mg	14	4.4	4.4
Docusate Sodium - Sennosides	44	4.4	4.4
Amitriptyline Hydrochloride	24	4.4	4.4
Carisoprodol	26	4.4	4.4
Amiodarone Hydrochloride	15	4.3	4.3
Celecoxib	172	4.3	4.3
Irbesartan	58	4.2	4.2
Hydroxyzine Hydrochloride	17	4.2	4.2
Hydroxyzine Hydrochloride Oral	17	4.2	4.2
Ascorbic Acid	30	4.2	4.2
Lisinopril	376	4.1	4.1
Temazepam	47	4.0	4.0
Ibuprofen And Diphenhydramine Citrate	29	4.0	4.0
Loperamide Hcl	16	4.0	4.0
Rabeprazole	27	3.9	3.9
Conjugated Estrogens	70	3.9	3.9
Doxazosin Mesylate	43	3.8	3.9
Febuxostat	20	3.8	3.8
Estrogens, Conjugated	70	3.8	3.8
Hydrochlorothiazide	168	3.8	3.8
Ritonavir	34	3.8	3.8
Quinine	10	3.8	3.8
Docusate Sodium	66	3.7	3.7
Lisinopril And Hydrochlorothiazide Tablets	9	3.7	3.7
Bicalutamide	17	3.6	3.6
Pravastatin Sodium	22	3.6	3.6
Lopinavir And Ritonavir	15	3.6	3.6
Chlorhexidine Gluconate	10	3.5	3.5
Methoxy Polyethylene Glycol-Epoetin Beta	12	3.5	3.5
Finasteride	65	3.5	3.5
Enoxaparin Sodium	62	3.5	3.5
Doxazosin	30	3.5	3.5
Lovastatin	27	3.4	3.4
Naproxen	82	3.4	3.4
Tamsulosin Hydrochloride	21	3.3	3.3
Desloratadine	11	3.3	3.3
Dapagliflozin	32	3.3	3.3
Canakinumab	11	3.3	3.3
Methocarbamol	23	3.3	3.3
Telmisartan	18	3.2	3.3
Ritonavir 100 Mg	15	3.2	3.2
Methylprednisolone Acetate	8	3.2	3.2
Testosterone	23	3.2	3.2
Insulin Human	39	3.2	3.2
Ranibizumab	26	3.2	3.2
Raltegravir	16	3.1	3.1
Magnesium Hydroxide	13	3.1	3.1
Raloxifene Hydrochloride	14	3.1	3.1
Standardized Senna Concentrate	12	3.1	3.1
Icosapent Ethyl	8	3.0	3.0
Candesartan	33	3.0	3.0
Erythropoietin	19	3.0	3.0
Ketoprofen	12	2.9	2.9
Potassium Chloride	103	2.9	2.9
Timolol Maleate	9	2.9	2.9
Terbinafine Hydrochloride	8	2.9	2.9
Valsartan Oral	48	2.9	2.9
Loperamide Hydrochloride Oral	9	2.8	2.8
Docusate Sodium 100Mg	21	2.8	2.8
Esomeprazole Magnesium	201	2.8	2.8
Glimepiride	34	2.8	2.8
Losartan	150	2.8	2.8
Agalsidase Beta	8	2.8	2.8
Dutasteride	7	2.8	2.8
Famotidine	100	2.8	2.8
Potassium Chloride, Dextrose Monohydrate	79	2.8	2.8
Potassium Chloride Oral	79	2.8	2.8
Potassium Chloride Extended-Release	79	2.8	2.8
Acetylcysteine	8	2.7	2.7
Zolpidem Tartrate	113	2.7	2.7
Atropine	7	2.7	2.7
Lansoprazole	148	2.7	2.7
Iron Sucrose	8	2.7	2.7
Darbepoetin Alfa	45	2.7	2.7
Labetalol	11	2.7	2.7
Pantoprazole Sodium	121	2.7	2.7
Paroxetine Hydrochloride	74	2.6	2.6
Ciprofloxacin Hydrochloride And Hydrocortisone	17	2.6	2.6
Nebivolol	13	2.6	2.6
Allopurinol	126	2.6	2.6
Azithromycin Dihydrate	47	2.6	2.6
Clonidine	41	2.6	2.6
Heparin Sodium	11	2.6	2.6
Sertraline Hydrochloride	94	2.6	2.6
Olmesartan Medoxomil	28	2.5	2.5
Insulin Glargine-Yfgn	17	2.5	2.5
Hydroxyzine	37	2.5	2.5
Methocarbamol Tablets	13	2.5	2.5
Tizanidine Hydrochloride	14	2.5	2.5
Sofosbuvir	15	2.4	2.4
Goserelin	10	2.4	2.4
Atropine Sulfate	8	2.4	2.4
Warfarin	93	2.4	2.4
Romosozumab-Aqqg	10	2.4	2.4
Warfarin Sodium	34	2.4	2.4
Alteplase	11	2.4	2.4
Romiplostim	11	2.4	2.4
Metformin Er 500 Mg	214	2.3	2.3
Metformin Er 750 Mg	214	2.3	2.3
Metformin	252	2.3	2.3
Conjugated Estrogens And Medroxyprogesterone Acetate	17	2.3	2.3
Metoclopramide Hydrochloride	55	2.3	2.3
Alprazolam	145	2.3	2.3
Fenofibrate	25	2.3	2.3
Calcitriol Capsules 0.25 Mcg	14	2.2	2.2
Calcitriol Capsules 0.5 Mcg	14	2.2	2.2
Calcitriol	14	2.2	2.2
Sitagliptin	49	2.2	2.2
Bumetanide	18	2.2	2.2
Metformin Hydrochloride Tablets	39	2.2	2.2
Metformin Hydrochloride Extended-Release Tablets	39	2.2	2.2
Metformin Hydrochloride Tablet	39	2.2	2.2
Amlodipine	181	2.2	2.2
Clobetasol Propionate Ointment Usp, 0.05%	7	2.2	2.2
Clobetasol Propionate	7	2.2	2.2
Naproxen Sodium	95	2.2	2.2
Metformin Hydrochloride	39	2.1	2.1
Vincristine Sulfate	19	2.1	2.1
Doxorubicin Hydrochloride	21	2.1	2.1
Capecitabine	58	2.0	2.0
Olanzapine Pamoate	26	2.0	2.0
Omeprazole Magnesium	277	2.0	2.0
Insulin Glargine	153	2.0	2.0
Tretinoin	5	2.0	2.0
Abacavir Sulfate	6	2.0	2.0
Linagliptin	11	1.9	1.9
Sotalol Hydrochloride	10	1.9	1.9
Hydrocodone Bitartrate	26	1.9	1.9
Nebivolol Hydrochloride	20	1.9	1.9
Rivaroxaban	122	1.9	1.9
Guaifenesin	18	1.9	1.9
Insulin Glulisine	6	1.9	1.9
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	12	1.9	1.9
Naproxen Sodium, Pseudoephedrine Hydrochloride	12	1.9	1.9
Dabigatran Etexilate	45	1.9	1.9
Acalabrutinib	7	1.9	1.9
Acetaminophen And Codeine	7	1.8	1.8
Melphalan	13	1.8	1.8
Melphalan Hydrochloride	14	1.8	1.8
Umeclidinium	5	1.8	1.8
Atazanavir	8	1.8	1.8
Insulin Aspart	36	1.8	1.8
Ibuprofen Tablets, Coated	23	1.7	1.7
Evolocumab	87	1.7	1.7
Ibuprofen Sodium	23	1.7	1.7
Tiotropium Bromide	71	1.7	1.7
Lenvatinib	17	1.7	1.7
Regorafenib	6	1.7	1.7
Aflibercept	16	1.7	1.7
Sitagliptin And Metformin Hydrochloride	11	1.6	1.6
Sacubitril And Valsartan	59	1.6	1.6
Loratadine And Pseudoephedrine Sulfate	4	1.6	1.6
Doxorubicin	44	1.6	1.6
Sorafenib	10	1.5	1.5
Latanoprost	24	1.5	1.5
Empagliflozin	32	1.5	1.5
Dofetilide	5	1.5	1.5
Oxaliplatin	35	1.5	1.5
Irinotecan Hydrochloride	6	1.5	1.5
Oxycodone Hydrochloride And Acetaminophen	46	1.5	1.5
Dabigatran Etexilate Mesylate	33	1.5	1.5
Bosutinib	4	1.4	1.4
Gefitinib	4	1.4	1.4
Azacitidine For	8	1.4	1.4
Sevelamer Carbonate	5	1.4	1.4
Entecavir	5	1.4	1.4
Tenofovir Disoproxil Fumarate	14	1.4	1.4
Bortezomib	36	1.3	1.3
Eltrombopag Olamine	9	1.3	1.3
Tofacitinib Citrate	5	1.2	1.2
Insulin Lispro	52	1.2	1.2
Azacitidine	11	1.2	1.2
Abiraterone	5	1.2	1.2
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	3	1.2	1.2
Interferon Beta-1B	7	1.2	1.2
Medroxyprogesterone Acetate	18	1.2	1.2
Temozolomide	7	1.1	1.1
Liraglutide	16	1.0	1.0
Ustekinumab	33	1.0	1.0
Erlotinib Hydrochloride	4	1.0	1.0
Carfilzomib	9	1.0	1.0
Erlotinib	3	1.0	1.0
Daratumumab	11	0.9	0.9
Brexpiprazole	4	0.8	0.8
Exenatide	12	0.7	0.7
Varenicline Tartrate	18	0.7	0.7
Cinacalcet Hydrochloride	10	0.7	0.7
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	5	0.5	0.5
Paliperidone Palmitate	5	0.5	0.5
Minoxidil Foam 5% (Womens)	5	0.5	0.5
Pirfenidone	6	0.5	0.5
Droxidopa	3	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.