Reaction

Which drugs are most reported with Uterine leiomyoma?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,241 reports · 211 co-occurring drugs

As of the last recalculation, Uterine Leiomyoma appears in 7,241 FAERS reports alongside 211 co-occurring drug terms. The strongest observed disproportionality signal is COPPER (PRR 27.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Copper	390	27.4	27.7
Etonogestrel And Ethinyl Estradiol	151	20.0	20.1
Leuprolide Acetate	326	12.6	12.7
Levonorgestrel	752	11.9	11.9
Interferon Beta-1A	547	8.7	8.7
Tranexamic Acid	26	8.4	8.5
Conjugated Estrogens And Medroxyprogesterone Acetate	67	8.2	8.2
Raloxifene Hydrochloride	38	7.5	7.5
Progesterone	57	7.2	7.2
Medroxyprogesterone Acetate	118	6.9	6.9
Iron	149	6.5	6.5
Goserelin	30	6.4	6.5
Alendronate Sodium	182	5.3	5.3
Anastrozole	67	5.3	5.3
Anastrozole Tablets	37	5.0	5.0
Doxepin Hydrochloride	21	4.8	4.8
Naltrexone Hydrochloride And Bupropion Hydrochloride	14	4.7	4.7
Mometasone	30	4.7	4.7
Doxepin	16	4.5	4.6
Promethazine Hydrochloride	29	4.5	4.5
Estradiol	131	4.4	4.4
Conjugated Estrogens	88	4.4	4.4
Estrogens, Conjugated	89	4.4	4.4
Ascorbic Acid	34	4.2	4.2
Modafinil	47	4.2	4.2
Ferrous Sulfate	69	4.0	4.0
Liothyronine Sodium	12	4.0	4.0
Docusate Sodium - Sennosides	44	3.9	3.9
Desoximetasone	26	3.9	3.9
Exemestane	29	3.9	3.9
Tretinoin	11	3.9	3.9
Sodium Oxybate	88	3.9	3.9
Tizanidine Hydrochloride	24	3.8	3.8
Diphenoxylate Hydrochloride And Atropine Sulfate	18	3.8	3.8
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	45	3.7	3.7
Vitamin E	40	3.7	3.7
Ibuprofen And Diphenhydramine Citrate	29	3.6	3.6
Sumatriptan Succinate	31	3.5	3.5
Tolterodine Tartrate	11	3.5	3.5
Thyroid, Porcine	13	3.5	3.5
Nitrofurantoin	20	3.5	3.5
Drospirenone And Ethinyl Estradiol	53	3.5	3.5
Chlorhexidine Gluconate	11	3.5	3.5
Fesoterodine Fumarate	13	3.5	3.5
Nitrofurantoin (Monohydrate/Macrocrystals)	20	3.4	3.5
Methylprednisolone Sodium Succinate	53	3.3	3.3
Misoprostol	11	3.3	3.3
Estradiol Gel 0.1%	50	3.2	3.2
Estradiol Transdermal	50	3.2	3.2
Mometasone Furoate	46	3.2	3.2
Hyoscyamine Sulfate	10	3.1	3.1
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	45	3.1	3.1
Letrozole	64	3.0	3.0
Cladribine	10	3.0	3.0
Natalizumab	185	3.0	3.0
Zinc Gluconate	27	3.0	3.0
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	163	3.0	3.0
Adalimumab	681	3.0	3.0
Lanreotide Acetate	8	2.9	2.9
Lisinopril And Hydrochlorothiazide Tablets	8	2.9	2.9
Canakinumab	11	2.9	2.9
Metronidazole	64	2.9	2.9
Armodafinil	21	2.9	2.9
Dicyclomine Hydrochloride	14	2.8	2.8
Sumatriptan	37	2.8	2.8
Esomeprazole	60	2.8	2.8
Mesalamine	54	2.8	2.8
Infliximab-Dyyb	28	2.8	2.8
Docusate Sodium	55	2.8	2.8
Metronidazole Topical	45	2.7	2.7
Biotin	29	2.7	2.7
Clindamycin Phosphate	31	2.7	2.7
Calcium, Magnesium, Potassium, And Sodium Oxybates	8	2.7	2.7
Multivitamin	46	2.7	2.7
Pertuzumab	25	2.6	2.7
Celecoxib	120	2.6	2.6
Clindamycin	26	2.6	2.6
Cholestyramine	11	2.6	2.6
Fluticasone Furoate	11	2.6	2.6
Azathioprine	79	2.6	2.6
Rizatriptan Benzoate	9	2.5	2.5
Levothyroxine Sodium	271	2.5	2.5
Lisinopril And Hydrochlorothiazide	9	2.5	2.5
Ibuprofen Capsule	173	2.5	2.5
Ibuprofen Tablet, Film Coated	173	2.5	2.5
Ibupfrofen	173	2.5	2.5
Ibuprofen Tablets Usp, 200Mg	173	2.5	2.5
Ibuprofen Oral	173	2.5	2.5
Ibuprofen Capsules 200 Mg	173	2.5	2.5
Ibuprofen 200 Mg	173	2.5	2.5
Ibuprofen 200Mg	173	2.5	2.5
Felodipine Extended-Release Tablets	10	2.5	2.5
Felodipine	10	2.5	2.5
Ibuprofen	234	2.5	2.5
Isosorbide Dinitrate	17	2.5	2.5
Acetylcysteine	8	2.4	2.4
Butalbital, Acetaminophen, And Caffeine	9	2.4	2.4
Ziprasidone Mesylate	12	2.4	2.4
Tofacitinib Citrate	11	2.4	2.4
Fingolimod Hcl	71	2.4	2.4
Magnesium	67	2.4	2.4
Folic Acid	201	2.4	2.4
Ibuprofen Sodium	35	2.4	2.4
Meclizine Hcl 12.5Mg	11	2.3	2.3
Meclizine Hcl 25Mg	11	2.3	2.3
Meclizine Hcl 12.5 Mg	11	2.3	2.3
Meclizine Hcl 25 Mg	11	2.3	2.3
Ibuprofen Tablets, Coated	34	2.3	2.3
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	8	2.3	2.3
Naproxen	62	2.3	2.3
Hydrochlorothiazide	114	2.3	2.3
Fulvestrant	26	2.3	2.3
Cyclobenzaprine	39	2.3	2.3
Interferon Beta-1B	15	2.3	2.3
Zolpidem Tartrate	105	2.3	2.3
Ergocalciferol	294	2.2	2.2
Oxymorphone Hydrochloride	9	2.2	2.2
Methotrexate	312	2.2	2.2
Sertraline Hydrochloride	89	2.2	2.2
Bupropion Hydrochloride	74	2.2	2.2
Lubiprostone	7	2.1	2.1
Upadacitinib	60	2.1	2.1
Ziprasidone	13	2.1	2.1
Lopinavir And Ritonavir	10	2.1	2.1
Baclofen	63	2.1	2.1
Fluoxetine Hydrochloride	93	2.1	2.1
Omalizumab	62	2.1	2.1
Fexofenadine	12	2.1	2.1
Meloxicam	42	2.1	2.1
Prochlorperazine	20	2.1	2.1
Montelukast Sodium	87	2.1	2.1
Tramadol Hydrochloride	27	2.1	2.1
Citalopram	97	2.1	2.1
Escitalopram	99	2.0	2.0
Amoxicillin	54	2.0	2.0
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	35	2.0	2.0
Eculizumab	38	2.0	2.0
Methotrexate Sodium	331	2.0	2.0
Dimethyl Fumarate	85	2.0	2.0
Chlorthalidone	8	2.0	2.0
Alpelisib	6	2.0	2.0
Glatiramer Acetate	41	2.0	2.0
Risankizumab-Rzaa	56	2.0	2.0
Ocrelizumab	42	2.0	2.0
Loratadine Oral	33	1.9	1.9
Dolutegravir Sodium	6	1.9	1.9
Valsartan And Hydrochlorothiazide	9	1.9	1.9
Sulfasalazine	51	1.9	1.9
Loratadine Tablet	35	1.9	1.9
Vedolizumab	56	1.9	1.9
Bupropion	29	1.9	1.9
Letrozole Tablets	31	1.9	1.9
Golimumab	55	1.8	1.9
Alprazolam	131	1.8	1.8
Loratadine	67	1.8	1.8
Trastuzumab	42	1.8	1.8
Raltegravir	10	1.7	1.7
Sitagliptin And Metformin Hydrochloride	13	1.7	1.7
Ofatumumab	20	1.7	1.7
Riociguat	19	1.7	1.7
Amantadine	9	1.7	1.7
Voclosporin	5	1.7	1.7
Eszopiclone	14	1.6	1.6
Liraglutide	27	1.6	1.6
Agalsidase Beta	5	1.6	1.6
Peginterferon Beta-1A	7	1.5	1.5
Desvenlafaxine Succinate	14	1.5	1.5
Erlotinib	5	1.5	1.5
Naproxen Sodium Tablet	27	1.5	1.5
Lisdexamfetamine Dimesylate	16	1.4	1.4
Erlotinib Hydrochloride	6	1.4	1.4
Ranitidine Hydrochloride	26	1.4	1.4
Docetaxel Anhydrous	32	1.4	1.4
Docetaxel	32	1.4	1.4
Ado-Trastuzumab Emtansine	4	1.4	1.4
Acetaminophen, Aspirin (Nsaid) And Caffeine	8	1.4	1.4
Selexipag	12	1.3	1.3
Etonogestrel	22	1.3	1.3
Methylphenidate	13	1.3	1.3
Dalfampridine	32	1.3	1.3
Belimumab	14	1.3	1.3
Acetaminophen, Aspirin, And Caffeine	9	1.2	1.2
Capecitabine	39	1.2	1.2
Diroximel Fumarate	5	1.2	1.2
Macitentan	29	1.2	1.2
Exenatide	22	1.2	1.2
Buprenorphine Hydrochloride, Naloxone Hydrochloride	10	1.2	1.2
Asfotase Alfa	4	1.1	1.1
Romiplostim	6	1.1	1.1
Bosentan	20	1.1	1.1
Crizotinib	5	1.1	1.1
Lapatinib	6	1.1	1.1
Teriflunomide	17	1.1	1.1
Abatacept	52	1.1	1.1
Certolizumab Pegol	44	1.1	1.1
Diclofenac Potassium	4	1.1	1.1
Etanercept	219	1.1	1.1
Pegvaliase-Pqpz	3	1.0	1.0
Orlistat	9	1.0	1.0
Oral Semaglutide	25	1.0	1.0
Vemurafenib	4	1.0	1.0
Eptinezumab-Jjmr	3	0.9	0.9
Cortisone Acetate	4	0.9	0.9
Ustekinumab	32	0.9	0.9
Voxelotor	7	0.9	0.9
Emtricitabine And Tenofovir Disoproxil Fumarate	13	0.8	0.8
Palbociclib	27	0.8	0.8
Ambrisentan	35	0.8	0.8
Alirocumab	6	0.7	0.7
Osimertinib	7	0.6	0.6
Tirzepatide	24	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.