Reaction

Blood Creatine Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,384 reports · 242 co-occurring drugs

As of the last recalculation, Blood Creatine Increased appears in 4,384 FAERS reports alongside 242 co-occurring drug terms. The strongest observed disproportionality signal is FELODIPINE EXTENDED-RELEASE TABLETS (PRR 20.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Felodipine Extended-Release Tablets	49	20.6	20.7
Felodipine	49	20.6	20.7
Dalteparin Sodium	41	18.6	18.6
Isosorbide Mononitrate	56	13.0	13.0
Emtricitabine And Tenofovir Alafenamide	27	11.4	11.4
Dextrose	28	10.2	10.2
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	38	10.0	10.1
Dextrose Monohydrate	28	10.0	10.0
Niraparib	44	9.5	9.5
Tenofovir Disoproxil Fumarate	63	9.2	9.2
Emtricitabine And Tenofovir Disoproxil Fumarate	82	8.7	8.7
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	16	8.5	8.5
Dolutegravir Sodium	16	8.4	8.5
Torsemide	58	8.4	8.4
Calcitriol Capsules 0.25 Mcg	35	8.3	8.4
Calcitriol Capsules 0.5 Mcg	35	8.3	8.4
Calcitriol	35	8.3	8.3
Remdesivir	22	7.9	7.9
Entecavir	19	7.8	7.8
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	16	7.6	7.6
Vortioxetine	26	7.3	7.3
Pertuzumab	41	7.2	7.2
Oseltamivir	12	7.2	7.2
Voclosporin	13	7.1	7.1
Avapritinib	18	7.1	7.1
Teduglutide	19	6.7	6.7
Quinine	12	6.7	6.7
Sodium Bicarbonate	31	6.4	6.4
Sodium Bicarbonate Injection,	31	6.4	6.4
Magnesium Sulfate In Water For	17	6.3	6.3
Valganciclovir	25	6.3	6.3
Valganciclovir Hydrochloride	25	6.3	6.3
Eplerenone	17	6.3	6.3
Linagliptin	24	6.3	6.3
Magnesium Sulfate Heptahydrate	17	6.2	6.2
Abemaciclib	26	6.2	6.2
Magnesium Sulfate	17	6.2	6.2
Lithium Carbonate	22	6.2	6.2
Sacubitril And Valsartan	146	6.1	6.2
Ramipril	155	6.1	6.1
Enalapril Maleate	31	6.0	6.0
Piperacillin And Tazobactam	16	6.0	6.0
Doxazosin Mesylate	44	5.8	5.8
Bosutinib	11	5.8	5.8
Dapagliflozin	38	5.8	5.8
Piperacillin Sodium,Tazobactam Sodium	32	5.8	5.8
Phytonadione	10	5.6	5.6
Tacrolimus	177	5.5	5.6
Cefuroxime	13	5.4	5.4
Lopinavir And Ritonavir	15	5.3	5.3
Deferasirox	29	5.2	5.2
Spironolactone	147	5.1	5.1
Mycophenolic Acid	34	5.1	5.1
Bumetanide	28	5.1	5.1
Diltiazem Hydrochloride Extended-Release Tablets	12	5.0	5.0
Enalapril	58	5.0	5.0
Sunitinib Malate	41	5.0	5.0
Tacrolimus Extended-Release Capsules	128	5.0	5.0
Captopril	10	4.9	5.0
Tacrolimus Ointment 0.1%	126	4.9	4.9
Norepinephrine	11	4.9	4.9
Digoxin	72	4.8	4.8
Allopurinol	152	4.7	4.7
Potassium Chloride, Dextrose Monohydrate	91	4.7	4.7
Potassium Chloride Oral	91	4.7	4.7
Potassium Chloride Extended-Release	91	4.7	4.7
Clarithromycin	34	4.7	4.7
Bisoprolol Fumarate	132	4.7	4.7
Donepezil Hydrochloride	36	4.7	4.7
Metolazone	11	4.7	4.7
Norepinephrine Bitartrate	14	4.6	4.6
Metoclopramide	53	4.6	4.6
Piperacillin Sodium And Tazobactam Sodium	19	4.6	4.6
Mesna Injection	8	4.6	4.6
Mycophenilic Acid	20	4.6	4.6
Sirolimus	13	4.6	4.6
Furosemide	360	4.6	4.6
Fluorouracil	73	4.5	4.5
Gentamicin Sulfate	15	4.5	4.5
Mesna	8	4.5	4.5
Durvalumab	19	4.4	4.5
Vancomycin Hydrochloride	61	4.4	4.4
Hydroxyzine	44	4.4	4.4
Fluorouracil Cream, 0.5%	70	4.4	4.4
Ribociclib	29	4.4	4.4
Gentamicin	12	4.4	4.4
Hydroxyzine Hydrochloride	12	4.3	4.3
Hydroxyzine Hydrochloride Oral	12	4.3	4.3
Timolol	11	4.3	4.3
Olaparib	19	4.3	4.3
Valganciclovir Hydrochloride Powder,	11	4.3	4.3
Labetalol	12	4.3	4.3
Tranexamic Acid	8	4.3	4.3
Doxazosin	25	4.3	4.3
Ifosfamide	19	4.2	4.2
Amphotericin B	11	4.2	4.2
Amlodipine Besylate	126	4.2	4.2
Metoclopramide Hydrochloride	67	4.2	4.2
Diphenoxylate Hydrochloride And Atropine Sulfate	12	4.2	4.2
Ciprofolxacin	62	4.2	4.2
Ciprofloxacin Tablets	62	4.2	4.2
Heparin Sodium	12	4.2	4.2
Vancomycin	50	4.1	4.1
Daptomycin	8	4.1	4.1
Potassium Chloride	97	4.1	4.1
Losartan Potassium And Hydrochlorothiazide	10	4.1	4.1
Ciprofloxacin	78	4.1	4.1
Hydrochlorothiazide	122	4.1	4.1
Ciprofloxacin Hydrochloride	82	4.1	4.1
Basiliximab	10	4.0	4.0
Pemetrexed	18	4.0	4.0
Baricitinib	8	3.9	3.9
Tolvaptan	12	3.9	3.9
Cyclosporine	90	3.9	3.9
Tenofovir Disoproxil Fumarate Tablets	7	3.9	3.9
Diphenhydramine Hcl	9	3.8	3.8
Theophylline Anhydrous	10	3.8	3.8
Ritonavir 100 Mg	12	3.8	3.8
Ondansetron	86	3.8	3.8
Ondansetron Tablets	86	3.8	3.8
Docetaxel Anhydrous	53	3.8	3.8
Docetaxel	53	3.8	3.8
Rifampicin	8	3.8	3.8
Terazosin Hydrochloride	7	3.7	3.7
Dronedarone	8	3.7	3.7
Mycophenolate Mofetil	104	3.7	3.7
Sulfamethoxazole And Trimethoprim	65	3.7	3.7
Mycophenolate Mofetil Hydrochloride	104	3.7	3.7
Everolimus Tablets	13	3.7	3.7
Insulin	43	3.7	3.7
Atorvastatin Calcium, Film Coated	54	3.7	3.7
Gefitinib	7	3.7	3.7
Ciprofloxacin Hydrochloride And Hydrocortisone	16	3.7	3.7
Trastuzumab	52	3.6	3.6
Agalsidase Beta	7	3.6	3.6
Dutasteride	6	3.5	3.5
Leucovorin Calcium	14	3.5	3.5
Insulin Glargine-Yfgn	16	3.5	3.5
Ceftriaxone Sodium	28	3.5	3.5
Gemfibrozil	11	3.4	3.4
Metoprolol Tartrate Injection	134	3.4	3.4
Ondansetron Hydrochloride	87	3.4	3.4
Empagliflozin	48	3.4	3.4
Pemetrexed Disodium	27	3.4	3.4
Micafungin Sodium	6	3.4	3.4
Glyburide	17	3.3	3.3
Irbesartan	31	3.3	3.3
Letrozole Tablets	33	3.3	3.3
Alpelisib	6	3.3	3.3
Brentuximab Vedotin	7	3.2	3.2
Metoprolol	169	3.2	3.2
Warfarin Sodium	31	3.2	3.2
Metoprolol Tartrate	178	3.2	3.2
Isosorbide Dinitrate	13	3.2	3.2
Simvastatin	162	3.2	3.2
Ritonavir	19	3.1	3.1
Everolimus	33	3.1	3.1
Zoledronic Acid	26	3.1	3.1
Amikacin	11	3.1	3.1
Cisplatin	50	3.1	3.1
Ursodiol	14	3.1	3.1
Sodium Chloride Tablet	47	3.1	3.1
Sodium Chloride Tablets	47	3.1	3.1
Pyrazinamide	6	3.0	3.0
Rosuvastatin	126	3.0	3.0
Dabigatran Etexilate	48	3.0	3.0
Anti-Thymocyte Globulin (Rabbit)	5	2.9	2.9
Ursosiol	12	2.9	2.9
Isoniazid	10	2.9	2.9
Abacavir Sulfate	6	2.9	2.9
Lutetium Lu 177 Vipivotide Tetraxetan	8	2.9	2.9
Chlorthalidone	7	2.9	2.9
Metformin Hcl	33	2.8	2.8
Atorvastatin Calcium	145	2.8	2.8
Febuxostat	10	2.8	2.8
Insulin Glulisine	6	2.8	2.8
Sitagliptin	42	2.8	2.8
Erythropoietin	12	2.8	2.8
Carvedilol	78	2.8	2.8
Oxybutynin	17	2.8	2.8
Oseltamivir Phosphate	14	2.7	2.7
Paricalcitol	8	2.7	2.7
Cefepime	8	2.7	2.7
Lamivudine	17	2.6	2.6
Crizotinib	7	2.6	2.6
Acyclovir	62	2.6	2.6
Pioglitazone	23	2.5	2.5
Insulin Aspart	35	2.5	2.5
Darunavir	8	2.5	2.5
Thiotepa	5	2.5	2.5
Darbepoetin Alfa	28	2.5	2.5
Apixaban	34	2.4	2.4
Encorafenib	5	2.4	2.4
Cytarabine	30	2.4	2.4
Derma Foam Excel Hand Sanitizer	4	2.4	2.4
Ethanol	4	2.4	2.4
Atazanavir	7	2.3	2.3
Oxaliplatin	35	2.2	2.3
Icosapent Ethyl	4	2.2	2.2
Axitinib	9	2.2	2.2
Eculizumab	25	2.2	2.2
Cabozantinib	22	2.2	2.2
Pegfilgrastim	45	2.2	2.2
Ixazomib	13	2.1	2.1
Pembrolizumab	47	2.1	2.1
Ticagrelor	14	2.1	2.1
Tafamidis	5	2.0	2.0
Carboplatin	52	2.0	2.0
Palbociclib	39	1.9	2.0
Canagliflozin	12	1.9	1.9
Dofetilide	4	1.8	1.8
Trifluridine And Tipiracil	4	1.8	1.8
Canakinumab	4	1.8	1.8
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	3	1.7	1.7
Sevoflurane	3	1.7	1.7
Ruxolitinib	25	1.7	1.7
Eltrombopag Olamine	8	1.6	1.6
Asenapine Maleate	3	1.6	1.6
Rucaparib	3	1.6	1.6
Lenvatinib	11	1.6	1.6
Vemurafenib	4	1.6	1.6
Pazopanib Hydrochloride	9	1.6	1.6
Acalabrutinib	4	1.6	1.6
Oral Semaglutide	24	1.6	1.6
Cetuximab	10	1.5	1.5
Ravulizumab	4	1.4	1.4
Abiraterone	4	1.4	1.4
Pseudoephedrine Hydrochloride	3	1.4	1.4
Patiromer	4	1.4	1.4
Ranolazine	3	1.4	1.4
Pseudoephedrine Hcl	3	1.3	1.3
Exenatide	14	1.3	1.3
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	8	1.2	1.2
Velpatasvir And Sofosbuvir	3	1.1	1.1
Lenalidomide	96	1.1	1.1
Osimertinib	7	1.0	1.0
Dulaglutide	19	1.0	1.0
Minoxidil Foam 5% (Womens)	6	0.9	0.9
Abaloparatide	5	0.8	0.8
Cinacalcet Hydrochloride	7	0.7	0.7
Nirmatrelvir And Ritonavir	8	0.7	0.7
Minoxidil	6	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.