Reaction

Hepatic Lesion reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,264 reports · 208 co-occurring drugs

As of the last recalculation, Hepatic Lesion appears in 4,264 FAERS reports alongside 208 co-occurring drug terms. The strongest observed disproportionality signal is OCTREOTIDE ACETATE (PRR 53.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Octreotide Acetate	314	53.9	54.5
Ribociclib	169	27.2	27.3
Fulvestrant	175	26.9	27.1
Exemestane	100	23.3	23.4
Everolimus	211	21.2	21.3
Everolimus Tablets	70	20.7	20.8
Letrozole	216	18.0	18.0
Lanreotide Acetate	27	16.9	17.0
Panitumumab	52	16.4	16.4
Goserelin	43	15.8	15.8
Sorafenib	65	15.5	15.5
Letrozole Tablets	141	14.8	14.8
Alpelisib	25	14.1	14.1
Capecitabine	219	12.3	12.3
Ado-Trastuzumab Emtansine	21	12.2	12.2
Regorafenib	28	11.8	11.9
Anastrozole Tablets	45	10.3	10.4
Zoledronic Acid	83	10.3	10.3
Niraparib	46	10.2	10.2
Chlorhexidine Gluconate	17	9.1	9.1
Atezolizumab	68	8.7	8.7
Anastrozole	64	8.6	8.6
Pertuzumab	45	8.2	8.2
Instalax Polyethylene Glycol 3350	19	7.5	7.5
Temozolomide	32	7.5	7.5
Lenvatinib	49	7.4	7.4
Polyethylene Glycol 400	19	7.3	7.4
Terbinafine Hydrochloride	13	7.2	7.2
Ampicillin	12	7.1	7.1
Ampicillin Sodium	12	7.1	7.1
Fluorouracil Cream, 0.5%	107	7.0	7.0
Fluorouracil	108	7.0	7.0
Trastuzumab	95	6.9	6.9
Cefepime	20	6.8	6.8
Bevacizumab	167	6.8	6.8
Febuxostat Tablets 40 Mg	14	6.7	6.7
Febuxostat Tablets 80 Mg	14	6.7	6.7
Irinotecan Hydrochloride	17	6.5	6.5
Ifosfamide	28	6.4	6.4
Oxaliplatin	95	6.4	6.4
Sofosbuvir	25	6.2	6.2
Prochlorperazine	35	6.2	6.2
Leucovorin Calcium	24	6.2	6.2
Cefepime Hydrochloride	20	6.1	6.1
Diphenoxylate Hydrochloride And Atropine Sulfate	17	6.1	6.1
Pazopanib Hydrochloride	33	6.0	6.0
Palbociclib	114	6.0	6.0
Sitagliptin And Metformin Hydrochloride	26	5.9	5.9
Rifaximin	25	5.9	5.9
Cytarabine	71	5.8	5.9
Standardized Senna Concentrate	15	5.8	5.8
Imatinib Mesylate	33	5.8	5.8
Doxepin	12	5.8	5.8
Gemcitabine Hydrochloride	62	5.8	5.8
Loperamide Hydrochloride And Dimethicone	37	5.7	5.7
Morphine	84	5.6	5.6
Paclitaxel	109	5.5	5.5
Cisplatin	86	5.5	5.5
Bicalutamide	17	5.5	5.5
Doxorubicin Hydrochloride	36	5.4	5.4
Gemcitabine	43	5.4	5.4
Dabrafenib	23	5.4	5.4
Prochlorperazine Maleate	10	5.3	5.3
Trametinib	26	5.3	5.3
Cholestyramine	13	5.3	5.3
Sunitinib Malate	42	5.3	5.3
Docetaxel Anhydrous	71	5.2	5.2
Docetaxel	71	5.2	5.2
Vincristine Sulfate	31	5.2	5.2
Iron Sucrose	10	5.1	5.1
Posaconazole	17	5.1	5.1
Erlotinib Hydrochloride	13	5.1	5.1
Amphotericin B	13	5.1	5.1
Lapatinib	16	5.0	5.1
Posaconazole Delayed-Release	11	4.9	4.9
Paclitaxel (Aibumin-Bound)	81	4.9	4.9
Dronabinol	8	4.9	4.9
Anti-Thymocyte Globulin (Rabbit)	8	4.8	4.9
Nystatin	27	4.8	4.8
Loperamide Hydrochloride	43	4.7	4.7
Magnesium Hydroxide	13	4.7	4.7
Doxepin Hydrochloride	12	4.6	4.7
Dalteparin Sodium	10	4.6	4.6
Doxorubicin	82	4.6	4.6
Bisacodyl Suppositories	12	4.5	4.5
Cephalexin	20	4.5	4.5
Polatuzumab Vedotin	9	4.5	4.5
Biscodyl	12	4.5	4.5
Piperacillin Sodium And Tazobactam Sodium	18	4.5	4.5
Nystatin Ointment	24	4.5	4.5
Nystatin Cream	24	4.5	4.5
Sitagliptin	65	4.5	4.5
Temazepam	34	4.4	4.4
Rucaparib	8	4.4	4.4
Docusate Sodium - Sennosides	29	4.4	4.4
Febuxostat	15	4.4	4.4
Fam-Trastuzumab Deruxtecan-Nxki	9	4.4	4.4
Rifampicin	9	4.3	4.4
Fondaparinux Sodium	7	4.2	4.2
Losartan Potassium And Hydrochlorothiazide	10	4.2	4.2
Etonogestrel And Ethinyl Estradiol	19	4.2	4.2
Bisacodyl	12	4.2	4.2
Pemetrexed	18	4.1	4.1
Melphalan	19	4.1	4.1
Pancrelipase	32	4.1	4.1
Erlotinib	8	4.0	4.0
Micafungin Sodium	7	4.0	4.0
Enoxaparin Sodium	47	4.0	4.0
Valganciclovir Hydrochloride Powder,	10	4.0	4.0
Pegaspargase	10	4.0	4.0
Nebivolol	13	4.0	4.0
Carboplatin	102	4.0	4.0
Olaparib	17	4.0	4.0
Axicabtagene Ciloleucel	8	4.0	4.0
Melphalan Hydrochloride	20	3.9	3.9
Docusate Sodium 100Mg	19	3.9	3.9
Piperacillin And Tazobactam	10	3.8	3.8
Etoposide	57	3.8	3.8
Ledipasvir And Sofosbuvir	15	3.8	3.8
Ciprofloxacin Hydrochloride And Hydrocortisone	16	3.8	3.8
Lisinopril And Hydrochlorothiazide Tablets	6	3.7	3.7
Amikacin	13	3.7	3.7
Dorzolamide Hydrochloride And Timolol Maleate	6	3.7	3.7
Meropenem	24	3.7	3.7
Cyclophosphamide Injection, Solution	128	3.6	3.6
Cyclophosphamide	128	3.6	3.6
Cyclophosphamide For Injection	128	3.6	3.6
Rabeprazole Sodium	20	3.6	3.6
Ezetimibe And Simvastatin	11	3.5	3.5
Diphenhydramine Hcl	8	3.5	3.5
Tiotropium Bromide Inhalation Spray	8	3.5	3.5
Crizotinib	9	3.5	3.5
Salmeterol Xinafoate	6	3.4	3.4
Tenofovir Disoproxil Fumarate Tablets	6	3.4	3.4
Filgrastim	26	3.4	3.4
Mercaptopurine	12	3.4	3.4
Valganciclovir	13	3.4	3.4
Valganciclovir Hydrochloride	13	3.4	3.4
Ursosiol	13	3.3	3.3
Tobramycin Solution	8	3.3	3.3
Avapritinib	8	3.2	3.2
Ipilimumab	28	3.2	3.2
Tobramycin Sulfate	8	3.2	3.2
Ursodiol	14	3.1	3.1
Linezolid	19	3.1	3.1
Erythropoietin	13	3.1	3.1
Vancomycin	36	3.1	3.1
Isoniazid	10	3.0	3.0
Rifampin	9	3.0	3.0
Fludarabine Phosphate	24	3.0	3.0
Pemetrexed Disodium	23	3.0	3.0
Nivolumab	58	3.0	3.0
Vancomycin Hydrochloride	39	2.9	2.9
Dexamethasone Sodium Phosphate	6	2.9	2.9
Lopinavir And Ritonavir	8	2.9	2.9
Eszopiclone	15	2.9	2.9
Bendamustine Hcl	9	2.8	2.8
Ribavirin	37	2.8	2.8
Cetuximab	18	2.8	2.8
Interferon Beta-1B	11	2.8	2.8
Trifluridine And Tipiracil	6	2.7	2.7
Gefitinib	5	2.7	2.7
Voriconazole Injection	12	2.7	2.7
Darbepoetin Alfa	29	2.6	2.6
Voriconazole	16	2.6	2.6
Cladribine	5	2.5	2.5
Thalidomide	19	2.5	2.5
Polyethylene Glycol 3350	49	2.5	2.5
Entecavir	6	2.5	2.5
Mepolizumab	25	2.5	2.5
Denosumab	100	2.4	2.4
Bleomycin Sulfate	5	2.4	2.4
Granisetron	5	2.3	2.3
Hydromorphone Hydrochloride	43	2.3	2.3
Cabozantinib	22	2.2	2.2
Pembrolizumab	48	2.2	2.2
Methoxy Polyethylene Glycol-Epoetin Beta	5	2.2	2.2
Sevelamer Carbonate	5	2.1	2.1
Deferasirox	11	2.0	2.0
Tolvaptan	6	2.0	2.0
Acalabrutinib	5	2.0	2.0
Abemaciclib	8	2.0	2.0
Asfotase Alfa	4	2.0	2.0
Durvalumab	8	1.9	1.9
Morphine Sulfate	46	1.9	1.9
Lutetium Lu 177 Vipivotide Tetraxetan	5	1.9	1.9
Methadone Hydrochloride	4	1.8	1.8
Abiraterone	5	1.8	1.8
Glecaprevir And Pibrentasvir	4	1.8	1.8
Drospirenone And Ethinyl Estradiol	16	1.8	1.8
Axitinib	7	1.8	1.8
Cenobamate	3	1.8	1.8
Liraglutide	17	1.7	1.7
Diroximel Fumarate	4	1.6	1.6
Azacitidine For	6	1.6	1.6
Velpatasvir And Sofosbuvir	4	1.5	1.5
Venetoclax	19	1.5	1.5
Obinutuzumab	5	1.5	1.5
Tenofovir Disoproxil Fumarate	10	1.5	1.5
Peginterferon Alfa-2A	16	1.4	1.4
Exenatide	15	1.4	1.4
Paricalcitol	4	1.4	1.4
Osimertinib	9	1.4	1.4
Apalutamide	3	1.2	1.2
Abiraterone Acetate	10	1.2	1.2
Pegfilgrastim	23	1.1	1.1
Orlistat	6	1.1	1.1
Cinacalcet Hydrochloride	8	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.