OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Herpes Simplex reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,398 reports · 262 co-occurring drugs

As of the last recalculation, Herpes Simplex appears in 6,398 FAERS reports alongside 262 co-occurring drug terms. The strongest observed disproportionality signal is GLYCERIN, LIDOCAINE (PRR 184.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Glycerin, Lidocaine706184.3194.0
Docosanol706176.0184.9
Alemtuzumab21437.237.6
Busulfan15733.333.6
Fludarabine Phosphate32528.328.5
Thiotepa7826.927.1
Basiliximab9426.426.6
Anti-Thymocyte Globulin (Rabbit)5422.022.1
Valacyclovir Hydrochloride42821.121.2
Pegaspargase6116.416.4
Vincristine Sulfate13615.415.5
Posaconazole Delayed-Release4914.614.7
Mycophenolate Mofetil55214.414.4
Mycophenolate Mofetil Hydrochloride55214.414.4
Mercaptopurine7213.613.7
Valacyclovir16513.213.2
Sirolimus5413.113.2
Tacrolimus Ointment 0.1%46313.013.0
Tacrolimus Extended-Release Capsules46312.913.0
Filgrastim14412.712.8
Cytarabine22112.412.4
Valganciclovir Hydrochloride Powder,4211.311.3
Mycophenilic Acid7111.311.3
Acyclovir36811.111.1
Tacrolimus49511.111.1
Posaconazole5210.510.5
Ganciclovir3210.210.2
Methylprednisolone40210.010.1
Cyclophosphamide Injection, Solution4949.89.8
Cyclophosphamide4949.89.8
Cyclophosphamide For Injection4949.89.8
Ganciclovir Sodium319.69.6
Cyclosporine3119.59.5
Methylprednisolone Acetate239.49.4
Doxorubicin Hydrochloride878.88.8
Cefepime378.48.5
Valganciclovir488.38.4
Valganciclovir Hydrochloride488.38.4
Mycophenolic Acid818.38.3
Prednisolone4328.38.3
Prednisolone Oral4328.38.3
Prednisolone Oral Solution4328.38.3
Cefepime Hydrochloride397.97.9
Amphotericin B297.67.6
Melphalan527.57.5
Etoposide1657.57.5
Doxorubicin1897.17.1
Melphalan Hydrochloride547.17.1
Abacavir Sulfate217.07.0
Ifosfamide467.07.0
Mesna187.07.0
Meropenem687.07.0
Etonogestrel And Ethinyl Estradiol476.97.0
Mesna Injection176.76.7
Hydrocortisone Cream1306.46.4
Anti-Itch1296.46.4
Anti-Pruritic1296.46.4
Antipruritic (Anti-Itch)1296.46.4
Cool Relief Gel With Aloe1296.46.4
Drs. Hydrocortisone1296.46.4
Hydrocortisone Continuous Spray1296.46.4
Hydrocortisone Spray1296.46.4
Anti-Itch Cream1296.46.4
Hydrocortisone Lotion1296.46.4
Hydrocortisone Cream 1%1296.46.4
Hydrocortisone Cream 1/2%1296.46.4
Hydrocortisone 1%1296.46.4
Azathioprine1686.36.4
Blinatumomab206.36.3
Baricitinib186.16.1
Rituximab3716.06.0
Hydrocortisone Acetate1316.06.0
Bendamustine Hcl285.95.9
Acetylcysteine175.95.9
Nystatin Ointment445.55.5
Nystatin Cream445.55.5
Everolimus Tablets285.55.5
Nevirapine155.45.4
Piperacillin And Tazobactam215.45.4
Chlorhexidine Gluconate155.45.4
Nystatin445.35.3
Hydrocortisone1405.25.2
Zidovudine215.15.1
Voriconazole Injection345.15.1
Methylprednisolone Sodium Succinate725.15.1
Daspone155.05.0
Dapsone Gel, 5%155.05.0
Lamivudine475.05.0
Methotrexate5955.05.0
Obinutuzumab255.05.0
Ruxolitinib1074.94.9
Dapsone164.94.9
Prednisone6684.74.7
Methotrexate Sodium6474.74.7
Remdesivir194.64.7
Adalimumab-Fkjp654.64.6
Adalimumab-Aaty654.54.5
Atovaquone114.54.5
Fluconazole944.44.4
Ocrelizumab834.44.4
Atazanavir194.34.3
Voriconazole404.34.3
Isoniazid214.24.2
Adalimumab-Adaz674.24.2
Piperacillin Sodium,Tazobactam Sodium334.14.1
Amikacin214.04.0
Lamivudine Oral314.04.0
Piperacillin Sodium And Tazobactam Sodium244.04.0
Tofacitinib Citrate164.04.0
Vancomycin704.04.0
Human Immunoglobulin G254.04.0
Ritonavir 100 Mg183.93.9
Magnesium Sulfate In Water For153.83.8
Hydrocortisone Sodium Succinate113.83.8
Bendamustine Hydrochloride143.83.8
Clobetasol Propionate Ointment Usp, 0.05%123.83.8
Calcium Gluconate143.83.8
Clobetasol Propionate123.83.8
Magnesium Sulfate Heptahydrate153.83.8
Magnesium Sulfate153.73.7
Granisetron Hydrochloride123.73.7
Hydroxychloroquine853.73.7
Vancomycin Hydrochloride753.73.7
Imatinib203.73.7
Risedronate Sodium353.73.7
Sulfamethoxazole And Trimethoprim923.63.6
Ritonavir323.63.6
Cisplatin823.43.4
Upadacitinib853.43.4
Leucovorin Calcium203.43.4
Azithromycin423.43.4
Salmeterol Xinafoate93.43.4
Voclosporin93.43.4
Itraconazole123.33.3
Clindamycin293.33.3
Azithromycin Monohydrate423.33.3
Efavirenz113.23.2
Venetoclax603.23.2
Azithromycin Dihydrate573.23.2
Infliximab2073.23.2
Entecavir113.13.1
Tizanidine Hydrochloride173.13.1
Clindamycin Phosphate313.03.0
Dexamethasone2673.03.0
Dexamethasone 1.5 Mg2633.03.0
Anakinra152.92.9
Tobramycin Sulfate112.92.9
Lopinavir And Ritonavir122.92.9
Loratadine And Pseudoephedrine Sulfate72.92.9
Azacitidine262.92.9
Colchicine232.82.8
Mupirocin Calcium122.82.8
Enoxaparin Sodium492.82.8
Hydroxyurea182.82.8
Ampicillin72.82.8
Ampicillin Sodium72.82.8
Tobramycin Solution102.72.7
Azacitidine For152.72.7
Mupirocin112.72.7
Axicabtagene Ciloleucel82.62.6
Doxycycline552.62.6
Diphenhydramine Hcl92.62.6
Instalax Polyethylene Glycol 3350102.62.6
Doxycycline Hyclate542.62.6
Polyethylene Glycol 400102.62.6
Bortezomib702.62.6
Gefitinib72.52.5
Losartan Potassium And Hydrochlorothiazide92.52.5
Bleomycin Sulfate82.52.5
Zinc192.52.5
Cefazolin72.52.5
Panitumumab122.52.5
Zinc Chloride192.52.5
Thalidomide282.52.5
Hydroxyzine Hydrochloride102.52.5
Hydroxyzine Hydrochloride Oral102.52.5
Epoetin Alfa92.52.5
Torsemide252.52.5
Butalbital, Acetaminophen, And Caffeine82.42.4
Ursodiol162.42.4
Romiplostim112.42.4
Everolimus372.42.4
Cladribine72.42.4
Leflunomide752.32.3
Ursosiol142.32.3
Eculizumab392.32.3
Fingolimod Hcl612.32.3
Micafungin Sodium62.32.3
Progesterone162.32.3
Dexamethasone Sodium Phosphate72.22.2
Estradiol Gel 0.1%312.22.2
Estradiol Transdermal312.22.2
Brentuximab Vedotin72.22.2
Erythropoietin142.22.2
Prednisolone Acetate72.22.2
Granisetron72.22.2
Raltegravir112.22.2
Dolutegravir Sodium62.22.2
Darunavir102.22.2
Thyroid, Porcine72.12.1
Fexofenadine Hcl62.12.1
Isotretinoin322.12.1
Guselkumab232.12.1
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl322.12.1
Ceftriaxone212.12.1
Ibrutinib502.02.0
Ondansetron662.02.0
Ondansetron Tablets662.02.0
Benzonatate102.02.0
Ceftriaxone Sodium232.02.0
Miconazole Nitrate51.91.9
Norepinephrine61.81.8
Fluorouracil421.81.8
Prochlorperazine Maleate51.81.8
Pyrazinamide51.71.7
Carboplatin671.71.7
Fluorouracil Cream, 0.5%401.71.7
Oseltamivir41.61.6
Tobramycin121.61.6
Cabotegravir41.61.6
Faricimab41.61.6
Acetaminophen And Codeine61.61.6
Levetiracetam In Sodium Chloride381.61.6
Levetiracetam Oral381.61.6
Levetiracetam Injection381.61.6
Erlotinib Hydrochloride61.61.6
Pertuzumab131.61.6
Temozolomide101.51.5
Ado-Trastuzumab Emtansine41.51.5
Vortioxetine81.51.5
Canakinumab51.51.5
Mometasone Furoate And Formoterol Fumarate Dihydrate71.51.5
Emtricitabine And Tenofovir Alafenamide51.41.4
Secukinumab691.41.4
Bimekizumab91.41.4
Ofatumumab141.41.4
Ustekinumab431.41.4
Deferasirox111.41.4
Erlotinib41.31.3
Acalabrutinib51.31.3
Polatuzumab Vedotin41.31.3
Darbepoetin Alfa221.31.3
Sofosbuvir81.31.3
Tofacitinib691.21.2
Daratumumab141.11.1
Dasatinib131.11.1
Ipilimumab151.11.1
Dupilumab1621.11.1
Cetuximab101.01.0
Crisaborole31.01.0
Ledipasvir And Sofosbuvir61.01.0
Natalizumab561.01.0
Durvalumab61.01.0
Emtricitabine And Tenofovir Disoproxil Fumarate130.90.9
Glatiramer Acetate170.90.9
Ixekizumab100.90.9
Benralizumab50.80.8
Pegfilgrastim240.80.8
Orlistat50.60.6
Copper80.60.6
Lifitegrast30.60.6
Apremilast180.40.4

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.