Reaction

Cholangitis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,084 reports · 270 co-occurring drugs

As of the last recalculation, Cholangitis appears in 6,084 FAERS reports alongside 270 co-occurring drug terms. The strongest observed disproportionality signal is DURVALUMAB (PRR 43.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Durvalumab	248	43.4	44.0
Gemcitabine Hydrochloride	573	40.7	41.1
Gemcitabine	368	34.0	34.3
Irinotecan Hydrochloride	90	24.3	24.5
Ursodiol	144	23.1	23.3
Ursosiol	127	22.8	23.0
Everolimus Tablets	80	16.5	16.6
Nivolumab	416	15.7	15.8
Atezolizumab	172	15.6	15.6
Pembrolizumab	444	15.5	15.6
Cisplatin	302	13.9	13.9
Lenvatinib	126	13.4	13.4
Paclitaxel	335	12.2	12.2
Fluorouracil Cream, 0.5%	227	10.5	10.6
Erlotinib Hydrochloride	38	10.4	10.5
Fluorouracil	228	10.4	10.5
Panitumumab	47	10.3	10.4
Febuxostat Tablets 40 Mg	30	10.1	10.2
Febuxostat Tablets 80 Mg	30	10.1	10.2
Basiliximab	34	9.9	10.0
Leucovorin Calcium	50	9.0	9.0
Oxaliplatin	190	9.0	9.0
Piperacillin Sodium And Tazobactam Sodium	51	9.0	9.0
Erlotinib	25	8.9	8.9
Magnesium Oxide	106	8.8	8.8
Piperacillin And Tazobactam	32	8.6	8.6
Ipilimumab	103	8.3	8.3
Pemetrexed	51	8.2	8.2
Pemetrexed Disodium	89	8.1	8.1
Everolimus	117	8.0	8.0
Tacrolimus	338	7.8	7.8
Sorafenib	46	7.6	7.6
Meropenem	70	7.5	7.6
Ganciclovir Sodium	23	7.5	7.5
Ganciclovir	22	7.4	7.4
Tacrolimus Extended-Release Capsules	259	7.4	7.4
Tacrolimus Ointment 0.1%	257	7.3	7.3
Ceftriaxone Sodium	81	7.3	7.3
Lubiprostone	20	7.3	7.3
Paclitaxel (Aibumin-Bound)	169	7.2	7.2
Regorafenib	24	7.1	7.1
Piperacillin Sodium,Tazobactam Sodium	54	7.0	7.0
Ceftriaxone	66	6.9	7.0
Hydrocortisone Sodium Succinate	19	6.9	6.9
Bevacizumab	239	6.8	6.8
Pancrelipase	76	6.8	6.8
Loperamide Hcl	25	6.7	6.7
Loperamide Hydrochloride Oral	19	6.4	6.4
Ampicillin	15	6.2	6.2
Ampicillin Sodium	15	6.2	6.2
Febuxostat	30	6.1	6.2
Aprepitant	33	6.1	6.2
Dolutegravir Sodium	16	6.1	6.1
Trifluridine And Tipiracil	19	6.1	6.1
Mycophenolate Mofetil	231	6.0	6.0
Mycophenolate Mofetil Hydrochloride	231	6.0	6.0
Carboplatin	216	6.0	6.0
Esomeprazole Magnesium Capsule, Delayed Release	25	5.9	5.9
Esomeprazole Magnesium Delayed Release Capsules	25	5.9	5.9
Esomeprazole Magnesium Dihydrate	25	5.9	5.9
Sirolimus	23	5.9	5.9
Mycophenilic Acid	35	5.8	5.8
Lapatinib	26	5.8	5.8
Prochlorperazine Maleate	15	5.6	5.6
Octreotide Acetate	49	5.5	5.5
Rabeprazole	35	5.4	5.4
Lopinavir And Ritonavir	21	5.3	5.3
Mycophenolic Acid	49	5.3	5.3
Prednisolone	258	5.1	5.1
Prednisolone Oral	258	5.1	5.1
Prednisolone Oral Solution	258	5.1	5.1
Cetuximab	45	4.9	4.9
Granisetron Hydrochloride	15	4.9	4.9
Fexofenadine Hcl	13	4.8	4.8
Gentamicin	18	4.7	4.7
Capecitabine	124	4.7	4.7
Atovaquone	11	4.7	4.7
Amoxicillin And Clavulanate Potassium	37	4.7	4.7
Amikacin	23	4.6	4.6
Encorafenib	13	4.5	4.5
Cefuroxime	15	4.5	4.5
Suvorexant	17	4.5	4.5
Phytonadione	11	4.4	4.4
Dexamethasone Sodium Phosphate	13	4.4	4.4
Tenofovir Disoproxil Fumarate Tablets	11	4.4	4.4
Mercaptopurine	22	4.4	4.4
Gentamicin Sulfate	20	4.3	4.3
Rabeprazole Sodium	34	4.3	4.3
Granisetron	13	4.2	4.3
Adalimumab-Fkjp	57	4.2	4.2
Telmisartan	22	4.2	4.2
Dalteparin Sodium	13	4.2	4.2
Esomeprazole	74	4.1	4.1
Adalimumab-Aaty	56	4.1	4.1
Micafungin Sodium	10	4.0	4.0
Obinutuzumab	19	4.0	4.0
Lanreotide Acetate	9	3.9	3.9
Adalimumab-Adaz	60	3.9	3.9
Prochlorperazine	31	3.8	3.8
Fam-Trastuzumab Deruxtecan-Nxki	11	3.7	3.7
Atropine	9	3.7	3.7
Bisacodyl Suppositories	14	3.7	3.7
Efavirenz	12	3.7	3.7
Biscodyl	14	3.7	3.7
Metoclopramide	58	3.6	3.6
Insulin Glargine-Yfgn	23	3.6	3.6
Cimetidine	10	3.6	3.6
Sunitinib Malate	40	3.5	3.5
Atropine Sulfate	11	3.5	3.5
Levofloxacin	61	3.5	3.5
Levofloxacin In 5% Dextrose	61	3.5	3.5
Sofosbuvir	20	3.5	3.5
Cyclosporine	110	3.4	3.4
Dabrafenib	21	3.4	3.4
Bisacodyl	14	3.4	3.4
Dronabinol	8	3.4	3.4
Vancomycin	57	3.4	3.4
Anti-Thymocyte Globulin (Rabbit)	8	3.4	3.4
Linagliptin	18	3.4	3.4
Sitagliptin And Metformin Hydrochloride	21	3.3	3.3
Lamivudine	30	3.3	3.3
Metoclopramide Hydrochloride	74	3.3	3.3
Tolvaptan	14	3.3	3.3
Bisoprolol Fumarate	129	3.3	3.3
Trametinib	23	3.3	3.3
Vancomycin Hydrochloride	62	3.2	3.2
Norepinephrine	10	3.2	3.2
Axitinib	18	3.2	3.2
Rosuvastatin Calcium	26	3.2	3.2
Polyethylene Glycol	10	3.2	3.2
Abacavir Sulfate	9	3.2	3.2
Lactulose	35	3.1	3.1
Ketoprofen	12	3.1	3.1
Mesalamine	51	3.1	3.1
Sitagliptin	65	3.1	3.1
Tranexamic Acid	8	3.1	3.1
Indapamide	16	3.1	3.1
Rifampicin	9	3.0	3.0
Insulin Glulisine	9	3.0	3.0
Amphotericin B	11	3.0	3.0
Clobetasol Propionate Ointment Usp, 0.05%	9	3.0	3.0
Lamivudine Oral	22	3.0	3.0
Clobetasol Propionate	9	3.0	3.0
Sulfamethoxazole And Trimethoprim	72	2.9	2.9
Lansoprazole	148	2.9	2.9
Vemurafenib	10	2.8	2.9
Loperamide Hydrochloride	37	2.8	2.8
Cefazolin Sodium	10	2.8	2.8
Teduglutide	11	2.8	2.8
Pravastatin Sodium	16	2.8	2.8
Cefepime Hydrochloride	13	2.8	2.8
Sennosides	24	2.8	2.8
Esomeprazole Magnesium	184	2.7	2.7
Fosaprepitant Dimeglumine	11	2.7	2.7
Ciprofolxacin	57	2.7	2.7
Ciprofloxacin Tablets	57	2.7	2.7
Imatinib	14	2.7	2.7
Metronidazole	50	2.7	2.7
Pitavastatin Calcium	8	2.7	2.7
Azacitidine	23	2.7	2.7
Nevirapine	7	2.7	2.7
Dicyclomine Hydrochloride	11	2.6	2.6
Entecavir	9	2.6	2.6
Itraconazole	9	2.6	2.6
Ciprofloxacin	70	2.6	2.6
Norepinephrine Bitartrate	11	2.6	2.6
Clarithromycin	26	2.6	2.6
Ribavirin	48	2.6	2.6
Valacyclovir	31	2.6	2.6
Valganciclovir	14	2.5	2.5
Valganciclovir Hydrochloride	14	2.5	2.5
Ezetimibe	55	2.5	2.5
Vedolizumab	63	2.5	2.5
Azacitidine For	13	2.4	2.4
Insulin	39	2.4	2.4
Cefepime	10	2.4	2.4
Glimepiride	27	2.4	2.4
Oxybutynin Chloride	6	2.3	2.3
Dextrose	9	2.3	2.3
Insulin Degludec	16	2.3	2.3
Isoniazid	11	2.3	2.3
Prednisolone Acetate	7	2.3	2.3
Dextrose Monohydrate	9	2.3	2.3
Pioglitazone	29	2.3	2.3
Dapagliflozin	21	2.3	2.3
Bicalutamide	10	2.2	2.2
Valacyclovir Hydrochloride	46	2.2	2.2
Heparin Sodium	9	2.2	2.2
Infliximab-Dyyb	19	2.2	2.2
Fenofibrate	23	2.2	2.2
Metformin Hydrochloride Tablets	37	2.2	2.2
Metformin Hydrochloride Extended-Release Tablets	37	2.2	2.2
Metformin Hydrochloride Tablet	37	2.2	2.2
Ondansetron	69	2.2	2.2
Ondansetron Tablets	69	2.2	2.2
Nebivolol	10	2.1	2.2
Metformin Hydrochloride	37	2.1	2.1
Atazanavir	9	2.1	2.1
Levocetirizine Dihydrochloride	15	2.1	2.1
Ondansetron Hydrochloride	76	2.1	2.1
Vincristine Sulfate	18	2.1	2.1
Olmesartan Medoxomil	22	2.1	2.1
Raltegravir	10	2.1	2.1
Iohexol	5	2.1	2.1
Fexofenadine Hydrochloride	13	2.0	2.0
Ado-Trastuzumab Emtansine	5	2.0	2.0
Cabozantinib	28	2.0	2.0
Brinzolamide	5	2.0	2.0
Blinatumomab	6	2.0	2.0
Oxazepam	12	1.9	1.9
Liraglutide	27	1.9	1.9
Imatinib Mesylate	15	1.8	1.8
Docetaxel Anhydrous	36	1.8	1.8
Docetaxel	36	1.8	1.8
Deferasirox	14	1.8	1.8
Emtricitabine And Tenofovir Disoproxil Fumarate	24	1.8	1.8
Thiotepa	5	1.8	1.8
Oral Semaglutide	38	1.8	1.8
Bimekizumab	11	1.8	1.8
Apixaban	34	1.7	1.7
Etoposide	37	1.7	1.7
Trastuzumab	34	1.7	1.7
Prasugrel Hydrochloride	5	1.7	1.7
Pegaspargase	6	1.7	1.7
Dronedarone	5	1.7	1.7
Darbepoetin Alfa	26	1.7	1.7
Rifaximin	10	1.6	1.6
Eszopiclone	12	1.6	1.6
Metformin Hcl	26	1.6	1.6
Eculizumab	25	1.6	1.6
Tenofovir Disoproxil Fumarate	15	1.6	1.6
Vismodegib	4	1.5	1.5
Brimonidine Tartrate	8	1.5	1.5
Daratumumab	17	1.5	1.5
Polatuzumab Vedotin	4	1.4	1.4
Abemaciclib	8	1.4	1.4
Exenatide	21	1.4	1.4
Guselkumab	14	1.3	1.3
Insulin Glargine	95	1.3	1.3
Nintedanib	12	1.3	1.3
Ixekizumab	14	1.3	1.3
Bosentan	19	1.3	1.3
Remdesivir	5	1.3	1.3
Romosozumab-Aqqg	5	1.3	1.3
Drospirenone And Ethinyl Estradiol	16	1.2	1.2
Dabigatran Etexilate	28	1.2	1.2
Paricalcitol	5	1.2	1.2
Tirzepatide	57	1.2	1.2
Oxycodone Hydrochloride	73	1.2	1.2
Siponimod	3	1.2	1.2
Fentanyl Citrate	6	1.1	1.1
Olaparib	7	1.1	1.1
Pazopanib Hydrochloride	9	1.1	1.1
Gefitinib	3	1.1	1.1
Temozolomide	7	1.1	1.1
Romiplostim	5	1.1	1.1
Dabigatran Etexilate Mesylate	24	1.1	1.1
Dulaglutide	29	1.1	1.1
Aflibercept	10	1.1	1.1
Carfilzomib	9	1.1	1.1
Venetoclax	18	1.0	1.0
Methoxy Polyethylene Glycol-Epoetin Beta	3	0.9	0.9
Tapentadol Hydrochloride	9	0.9	0.9
Osimertinib	8	0.9	0.9
Emicizumab	3	0.8	0.8
Elexacaftor, Tezacaftor, And Ivacaftor	3	0.8	0.8
Abiraterone Acetate	9	0.7	0.7
Dornase Alfa	4	0.7	0.7
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	6	0.7	0.7
Pegfilgrastim	18	0.6	0.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.