Reaction

Inflammatory Marker Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,840 reports · 247 co-occurring drugs

As of the last recalculation, Inflammatory Marker Increased appears in 4,840 FAERS reports alongside 247 co-occurring drug terms. The strongest observed disproportionality signal is ANAKINRA (PRR 20.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Anakinra	79	20.8	20.9
Canakinumab	40	16.0	16.1
Cefuroxime	42	15.9	16.0
Tolterodine Tartrate	31	14.9	15.0
Adalimumab-Fkjp	143	13.6	13.7
Adalimumab-Aaty	145	13.6	13.6
Meropenem	99	13.5	13.6
Baricitinib	29	13.0	13.0
Dextrose	39	12.8	12.9
Dextrose Monohydrate	39	12.6	12.7
Adalimumab-Adaz	146	12.2	12.3
Eplerenone	36	12.2	12.2
Ampicillin	22	11.5	11.5
Ampicillin Sodium	22	11.5	11.5
Amphotericin B	32	11.1	11.1
Upadacitinib	193	10.6	10.6
Amiodarone Hydrochloride	27	10.4	10.4
Leflunomide	239	10.3	10.3
Piperacillin And Tazobactam	29	9.8	9.8
Adalimumab	1,216	9.5	9.6
Ceftriaxone	71	9.4	9.4
Amikacin	37	9.4	9.4
Sulfasalazine	163	9.2	9.3
Diclofenac Sodium 1%	75	9.2	9.2
Diclofenac Sodium Topical	75	9.2	9.2
Diclofenac Sodium Topical Gel, 1%	75	9.1	9.2
Remdesivir	28	9.1	9.1
Gentamicin	27	8.9	8.9
Ceftriaxone Sodium	78	8.9	8.9
Piperacillin Sodium,Tazobactam Sodium	51	8.3	8.4
Voriconazole Injection	41	8.2	8.2
Clarithromycin	64	8.1	8.1
Hydroxychloroquine Sulfate	160	7.8	7.8
Irbesartan	79	7.7	7.7
Gentamicin Sulfate	28	7.7	7.7
Torsemide	58	7.6	7.6
Hydroxychloroquine	129	7.6	7.6
Tofacitinib	307	7.6	7.6
Methotrexate Sodium	715	7.3	7.3
Methotrexate	628	7.2	7.2
Rosuvastatin Calcium	46	7.1	7.1
Piperacillin Sodium And Tazobactam Sodium	32	7.1	7.1
Thiamine Hydrochloride	20	6.9	6.9
Tofacitinib Citrate	21	6.9	6.9
Sennosides 8.6 Mg Tablets	33	6.8	6.8
Insulin Glulisine	16	6.8	6.8
Iron Sucrose	15	6.8	6.8
Thiotepa	15	6.8	6.8
Senna	33	6.8	6.8
Senna Leaf	36	6.8	6.8
Bendamustine Hcl	24	6.7	6.7
Vancomycin	87	6.6	6.6
Vancomycin Hydrochloride	99	6.6	6.6
Candesartan	54	6.6	6.6
Pemetrexed	32	6.5	6.5
Trimethoprim	17	6.2	6.2
Naproxen Sodium Tablet, Coated	19	6.1	6.1
Naproxen Sodium, Coated Tablets	19	6.1	6.1
Naproxen Sodium 220Mg	19	6.0	6.1
Vedolizumab	118	6.0	6.0
Voriconazole	42	6.0	6.0
Rifampicin	14	6.0	6.0
Valsartan Oral	74	5.9	5.9
Diclofenac	116	5.9	5.9
Prednisolone	235	5.8	5.8
Prednisolone Oral	235	5.8	5.8
Prednisolone Oral Solution	235	5.8	5.8
Bisoprolol Fumarate	178	5.8	5.8
Polatuzumab Vedotin	13	5.7	5.7
Methylprednisolone	178	5.7	5.7
Azathioprine	114	5.7	5.7
Mesalamine	73	5.7	5.7
Norepinephrine	14	5.6	5.7
Ascorbic Acid	30	5.6	5.6
Quinine	11	5.5	5.5
Naproxen	99	5.5	5.5
Cefepime	18	5.4	5.4
Folic Acid	297	5.4	5.4
Dimenhydrinate	13	5.3	5.3
Hydrocortisone	107	5.2	5.3
Fludarabine Phosphate	47	5.2	5.2
Golimumab	101	5.2	5.2
Nebivolol	19	5.1	5.2
Norepinephrine Bitartrate	17	5.1	5.1
Sennosides	35	5.1	5.1
Methylprednisolone Sodium Succinate	54	5.0	5.1
Risankizumab-Rzaa	92	4.9	4.9
Moxifloxacin Hydrochloride	23	4.9	4.9
Cefepime Hydrochloride	18	4.8	4.8
Ciprofolxacin	79	4.8	4.8
Ciprofloxacin Tablets	79	4.8	4.8
Azacitidine For	20	4.7	4.7
Tocilizumab	119	4.6	4.6
Infliximab	223	4.6	4.6
Rituximab	216	4.6	4.6
Meloxicam	60	4.5	4.5
Doxycycline Hyclate	69	4.4	4.4
Doxycycline	69	4.4	4.4
Busulfan	16	4.4	4.4
Esomeprazole	62	4.3	4.3
Tobramycin Solution	12	4.3	4.3
Isoniazid	16	4.3	4.3
Budesonide	57	4.2	4.2
Tobramycin Sulfate	12	4.2	4.2
Lactulose	37	4.2	4.2
Abatacept	131	4.2	4.2
Pyrazinamide	9	4.1	4.1
Acetylcysteine	9	4.1	4.1
Pantoprazole	233	4.1	4.1
Clindamycin	27	4.1	4.1
Pemetrexed Disodium	36	4.1	4.1
Micafungin Sodium	8	4.1	4.1
Pantoprazole Sodium In 0.9% Sodium Chloride	58	4.1	4.1
Pantoprazole Sodium Injection	58	4.1	4.1
Anti-Itch	62	4.0	4.0
Anti-Pruritic	62	4.0	4.0
Antipruritic (Anti-Itch)	62	4.0	4.0
Cool Relief Gel With Aloe	62	4.0	4.0
Drs. Hydrocortisone	62	4.0	4.0
Hydrocortisone Continuous Spray	62	4.0	4.0
Hydrocortisone Spray	62	4.0	4.0
Anti-Itch Cream	62	4.0	4.0
Hydrocortisone Lotion	62	4.0	4.0
Hydrocortisone Cream 1%	62	4.0	4.0
Hydrocortisone Cream 1/2%	62	4.0	4.0
Hydrocortisone 1%	62	4.0	4.0
Diclofenac Sodium	137	4.0	4.0
Hydrocortisone Cream	62	4.0	4.0
Certolizumab Pegol	107	4.0	4.0
Clopidogrel Bisulfate	93	4.0	4.0
Bendamustine Hydrochloride	11	4.0	4.0
Metformin Hydrochloride Tablets	52	3.9	3.9
Metformin Hydrochloride Extended-Release Tablets	52	3.9	3.9
Metformin Hydrochloride Tablet	52	3.9	3.9
Clindamycin Phosphate	30	3.9	3.9
Ciprofloxacin	81	3.8	3.8
Hydrocortisone Acetate	64	3.8	3.8
Metformin Hydrochloride	52	3.8	3.8
Nystatin Ointment	23	3.8	3.8
Nystatin Cream	23	3.8	3.8
Sarilumab	23	3.8	3.8
Daptomycin	8	3.7	3.7
Ciprofloxacin Hydrochloride	82	3.7	3.7
Dalteparin Sodium	9	3.7	3.7
Colchicine	22	3.6	3.6
Calcium Gluconate	10	3.6	3.6
Valsartan	86	3.6	3.6
Secukinumab	131	3.6	3.6
Doxazosin	23	3.5	3.5
Metronidazole Topical	39	3.5	3.5
Posaconazole Delayed-Release	9	3.5	3.5
Teduglutide	11	3.5	3.5
Metoprolol Succinate Er Tablets	50	3.5	3.5
Amoxicillin	61	3.5	3.5
Tacrolimus Ointment 0.1%	98	3.4	3.4
Tacrolimus Extended-Release Capsules	98	3.4	3.4
Tranexamic Acid	7	3.4	3.4
Brentuximab Vedotin	8	3.4	3.4
Sodium Chloride Tablet	57	3.4	3.4
Sodium Chloride Tablets	57	3.4	3.4
Amoxicillin And Clavulanate Potassium	21	3.3	3.3
Trazodone Hydrochloride	12	3.3	3.3
Levofloxacin	46	3.3	3.3
Levofloxacin In 5% Dextrose	46	3.3	3.3
Fexofenadine Hcl	7	3.3	3.3
Cytarabine	45	3.2	3.2
Levodopa	9	3.2	3.2
Midazolam Hydrochloride	20	3.2	3.2
Azacitidine	22	3.2	3.2
Nebivolol Hydrochloride	25	3.2	3.2
Fondaparinux Sodium	6	3.2	3.2
Sodium Chloride	58	3.2	3.2
Naproxen Sodium	104	3.2	3.2
Erythropoietin	15	3.1	3.1
Midazolam	18	3.1	3.1
Tacrolimus	109	3.0	3.0
Dapagliflozin	22	3.0	3.0
Haloperidol	17	3.0	3.0
Ifosfamide	15	3.0	3.0
Sevelamer Carbonate	8	3.0	3.0
Haloperidol Lactate	17	3.0	3.0
Etanercept	389	3.0	3.0
Ustekinumab	69	2.9	2.9
Mycophenilic Acid	14	2.9	2.9
Terbinafine Hydrochloride	6	2.9	2.9
Etoposide	49	2.9	2.9
Gemcitabine Hydrochloride	35	2.9	2.9
Pembrolizumab	69	2.8	2.8
Ibuprofen Tablets, Coated	28	2.8	2.8
Ibuprofen Sodium	28	2.8	2.8
Doxyclycline Hyclate	11	2.8	2.8
Fentanyl	63	2.8	2.8
Doxazosin Mesylate	23	2.7	2.7
Mercaptopurine	11	2.7	2.7
Doxorubicin	56	2.7	2.7
Aripiprazole Oral	26	2.7	2.7
Aripiprazole Orally Disintegrating	26	2.7	2.7
Tizanidine	15	2.7	2.7
Allopurinol	95	2.6	2.6
Tramadol Hydrochloride	23	2.6	2.6
Gemcitabine	24	2.6	2.6
Carboplatin	75	2.6	2.6
Insulin Glargine-Yfgn	13	2.6	2.6
Ocrelizumab	36	2.5	2.5
Granisetron Hydrochloride	6	2.5	2.5
Granisetron	6	2.5	2.5
Posaconazole	9	2.4	2.4
Rotigotine	8	2.4	2.4
Cyclophosphamide Injection, Solution	96	2.4	2.4
Cyclophosphamide	96	2.4	2.4
Cyclophosphamide For Injection	96	2.4	2.4
Nintedanib	17	2.3	2.3
Trametinib	13	2.3	2.3
Dabrafenib	11	2.2	2.2
Venetoclax	32	2.2	2.2
Palivizumab	8	2.2	2.2
Axicabtagene Ciloleucel	5	2.2	2.2
Empagliflozin	34	2.2	2.2
Linezolid	15	2.2	2.2
Tobramycin	12	2.1	2.1
Clozapine	62	2.1	2.1
Carfilzomib	14	2.1	2.1
Cortisone Acetate	6	2.1	2.1
Voclosporin	4	2.0	2.0
Guselkumab	16	1.9	1.9
Belimumab	14	1.9	1.9
Agalsidase Beta	4	1.9	1.9
Paricalcitol	6	1.8	1.8
Tapentadol Hydrochloride	14	1.8	1.8
Paclitaxel (Aibumin-Bound)	34	1.8	1.8
Oxaliplatin	30	1.7	1.7
Paclitaxel	36	1.6	1.6
Ozanimod Hydrochloride	3	1.6	1.6
Axitinib	7	1.5	1.5
Docetaxel Anhydrous	24	1.5	1.5
Docetaxel	24	1.5	1.5
Fremanezumab-Vfrm	4	1.5	1.5
Dabigatran Etexilate	26	1.4	1.4
Velpatasvir And Sofosbuvir	4	1.3	1.3
Apremilast	45	1.3	1.3
Ipilimumab	12	1.2	1.2
Canagliflozin	8	1.2	1.2
Durvalumab	5	1.1	1.1
Aflibercept	7	1.0	1.0
Ixekizumab	7	0.8	0.8
Bimekizumab	4	0.8	0.8
Tirzepatide	19	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.