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Which drugs are most reported with Large intestine polyp?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,840 reports · 362 co-occurring drugs

As of the last recalculation, Large Intestine Polyp appears in 6,840 FAERS reports alongside 362 co-occurring drug terms. The strongest observed disproportionality signal is OLMESARTAN MEDOXOMIL (PRR 82.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Olmesartan Medoxomil	857	82.8	84.8
Isotretinoin	359	23.3	23.4
Vedolizumab	435	16.3	16.4
Teduglutide	67	15.3	15.3
Cholestyramine	44	11.1	11.2
Mesalamine	198	11.0	11.1
Leucovorin Calcium	63	10.1	10.1
Hydrocortisone Sodium Succinate	31	10.1	10.1
Alendronate Sodium	285	8.9	8.9
Esomeprazole Magnesium Capsule, Delayed Release	41	8.6	8.7
Esomeprazole Magnesium Delayed Release Capsules	41	8.6	8.7
Esomeprazole Magnesium Dihydrate	41	8.6	8.6
Candesartan Cilexetil	61	7.1	7.1
Loperamide Hydrochloride And Dimethicone	70	6.7	6.7
Losartan Potassium And Hydrochlorothiazide	24	6.3	6.3
Hyoscyamine Sulfate	18	6.0	6.0
Iron	127	5.9	5.9
Tamsulosin Hydrochloride	39	5.8	5.9
Candesartan	67	5.8	5.8
Azathioprine	163	5.7	5.8
Chlorhexidine Gluconate	17	5.7	5.7
Dutasteride	15	5.6	5.6
Loperamide Hydrochloride	81	5.6	5.6
Infliximab-Dyyb	53	5.6	5.6
Sitagliptin And Metformin Hydrochloride	39	5.5	5.5
Octreotide Acetate	55	5.5	5.5
Eplerenone	23	5.5	5.5
Psyllium Husk	17	5.2	5.3
Valganciclovir	31	5.0	5.0
Valganciclovir Hydrochloride	31	5.0	5.0
Cannabidiol	38	5.0	5.0
Diphenoxylate Hydrochloride And Atropine Sulfate	22	4.9	4.9
Torsemide	53	4.9	4.9
Sodium Bicarbonate	37	4.9	4.9
Sodium Bicarbonate Injection,	37	4.9	4.9
Adalimumab	988	4.8	4.8
Sitagliptin	112	4.8	4.8
Apixaban	103	4.7	4.7
Doxazosin Mesylate	55	4.7	4.7
Midazolam Hydrochloride	40	4.5	4.5
Febuxostat Tablets 40 Mg	15	4.5	4.5
Febuxostat Tablets 80 Mg	15	4.5	4.5
Carvedilol	193	4.4	4.4
Ranolazine	15	4.4	4.4
Metronidazole	91	4.4	4.4
Doxazosin	40	4.4	4.4
Dicyclomine Hydrochloride	20	4.3	4.3
Quinapril Hydrochloride	11	4.2	4.3
Risedronate Sodium	43	4.2	4.2
Bicalutamide	21	4.2	4.2
Pitavastatin Calcium	14	4.2	4.2
Cyclobenzaprine Hydrochloride	12	4.1	4.1
Esomeprazole	82	4.1	4.1
Ferrous Sulfate	66	4.0	4.0
Selexipag	34	4.0	4.0
Rosuvastatin Calcium	37	4.0	4.0
Prochlorperazine Maleate	12	4.0	4.0
Hydrochlorothiazide	182	3.9	3.9
Basiliximab	15	3.9	3.9
Atorvastatin Calcium, Film Coated	87	3.8	3.8
Rabeprazole Sodium	34	3.8	3.8
Pancrelipase	48	3.8	3.8
Vitamin E	39	3.8	3.8
Dabigatran Etexilate	95	3.8	3.8
Cyclobenzaprine	61	3.7	3.7
Pantoprazole Sodium In 0.9% Sodium Chloride	75	3.7	3.7
Pantoprazole Sodium Injection	75	3.7	3.7
Amphotericin B	15	3.6	3.7
Risankizumab-Rzaa	97	3.6	3.7
Febuxostat	20	3.6	3.6
Pantoprazole	293	3.6	3.6
Docusate Sodium - Sennosides	38	3.6	3.6
Prasugrel Hydrochloride	12	3.6	3.6
Primidone	12	3.6	3.6
Telmisartan	21	3.6	3.6
Darbepoetin Alfa	63	3.6	3.6
Rabeprazole	26	3.6	3.6
Amlodipine Besylate	169	3.6	3.6
Calcium	169	3.5	3.5
Midazolam	29	3.5	3.5
Benzonatate	19	3.5	3.5
Liothyronine Sodium	10	3.5	3.5
Oxybutynin Chloride	10	3.5	3.5
Dabigatran Etexilate Mesylate	82	3.5	3.5
Brimonidine Tartrate	20	3.4	3.4
Ergocalciferol	413	3.4	3.4
Insulin	62	3.4	3.4
Esomeprazole Magnesium	254	3.4	3.4
Isosorbide Mononitrate	23	3.4	3.4
Valsartan Oral	60	3.4	3.4
Tolvaptan	16	3.4	3.4
Raloxifene Hydrochloride	16	3.3	3.3
Mycophenolic Acid	35	3.3	3.3
Linaclotide	29	3.3	3.3
Sucralfate	26	3.3	3.3
Ezetimibe	80	3.3	3.3
Ticagrelor	34	3.3	3.3
Valganciclovir Hydrochloride Powder,	13	3.2	3.2
Docusate Sodium	61	3.2	3.2
Mometasone Furoate	44	3.2	3.2
Salmeterol Xinafoate	9	3.2	3.2
Human Insulin	13	3.2	3.2
Cimetidine	10	3.2	3.2
Amoxicillin And Clavulanate Potassium	28	3.1	3.1
Budesonide	60	3.1	3.1
Fenofibrate	36	3.1	3.1
Magnesium	83	3.1	3.1
Ciprofloxacin Hydrochloride And Hydrocortisone	21	3.1	3.1
Bisoprolol Fumarate	135	3.1	3.1
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	50	3.1	3.1
Epoprostenol	13	3.0	3.0
Anti-Thymocyte Globulin (Rabbit)	8	3.0	3.0
Valsartan	103	3.0	3.0
Upadacitinib	80	3.0	3.0
Fluticasone Propionate And Salmeterol	41	3.0	3.0
Ipratropium Bromide	35	3.0	3.0
Mercaptopurine	17	3.0	3.0
Meperidine Hydrochloride	9	3.0	3.0
Labetalol	13	3.0	3.0
Cyanocobalamin	32	3.0	3.0
Fexofenadine Hcl	9	3.0	3.0
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	20	3.0	3.0
Naproxen Sodium, Pseudoephedrine Hydrochloride	20	3.0	3.0
Methocarbamol	22	3.0	3.0
Metronidazole Topical	46	3.0	3.0
Sulfasalazine	75	2.9	2.9
Thiamine Hydrochloride	12	2.9	2.9
Pantoprazole Sodium	141	2.9	2.9
Warfarin	121	2.9	2.9
Magnesium Oxide	40	2.9	2.9
Granisetron Hydrochloride	10	2.9	2.9
Rifaximin	20	2.9	2.9
Antacid	45	2.9	2.9
Clopidogrel	184	2.9	2.9
Irbesartan	42	2.9	2.9
Rosuvastatin	189	2.9	2.9
Potassium Chloride	106	2.9	2.9
Thyroid, Porcine	10	2.9	2.9
Nifedipine	44	2.8	2.9
Metoprolol Succinate	80	2.8	2.8
Epoetin Alfa	11	2.8	2.8
Ketoconazole	16	2.8	2.8
Travoprost	8	2.8	2.8
Atorvastatin Calcium	224	2.8	2.8
Tizanidine	22	2.8	2.8
Ezetimibe And Simvastatin	14	2.8	2.8
Alendronate Sodium Tablet	17	2.8	2.8
Metformin Hydrochloride	54	2.8	2.8
Nystatin	25	2.8	2.8
Finasteride	55	2.8	2.8
Rivaroxaban	187	2.8	2.8
Dexlansoprazole	38	2.8	2.8
Timolol	11	2.8	2.8
Clopidogrel Bisulfate	92	2.8	2.8
Methoxy Polyethylene Glycol-Epoetin Beta	10	2.8	2.8
Prednisone	433	2.7	2.7
Ciclesonide	12	2.7	2.7
Nitroglycerin	47	2.7	2.7
Nystatin Ointment	23	2.7	2.7
Felodipine Extended-Release Tablets	10	2.7	2.7
Felodipine	10	2.7	2.7
Latanoprost	44	2.7	2.7
Nystatin Cream	23	2.7	2.7
Ursosiol	17	2.7	2.7
Clobetasol Propionate Ointment Usp, 0.05%	9	2.7	2.7
Glipizide	53	2.7	2.7
Clobetasol Propionate	9	2.7	2.7
Furosemide	335	2.6	2.6
Testosterone	20	2.6	2.6
Bisacodyl	12	2.6	2.6
Bisacodyl Suppositories	11	2.6	2.6
Metoprolol Tartrate Injection	159	2.6	2.6
Lubiprostone	8	2.6	2.6
Omeprazole Magnesium	365	2.6	2.6
Biscodyl	11	2.6	2.6
Metformin Hydrochloride Tablets	48	2.6	2.6
Metformin Hydrochloride Extended-Release Tablets	48	2.6	2.6
Metformin Hydrochloride Tablet	48	2.6	2.6
Clonazepam	133	2.6	2.6
Oxycodone And Acetaminophen Tablets	10	2.6	2.6
Metoprolol Tartrate	225	2.6	2.6
Docusate Sodium 100Mg	20	2.5	2.6
Lactulose	32	2.5	2.5
Potassium Chloride, Dextrose Monohydrate	77	2.5	2.5
Potassium Chloride Oral	77	2.5	2.5
Potassium Chloride Extended-Release	77	2.5	2.5
Tadalafil	83	2.5	2.5
Polyethylene Glycol	9	2.5	2.5
Tizanidine Hydrochloride	15	2.5	2.5
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	131	2.5	2.5
Goserelin	11	2.5	2.5
Meclizine Hydrochloride	16	2.5	2.5
Amlodipine	216	2.5	2.5
Clindamycin Phosphate	27	2.5	2.5
Pravastatin Sodium	16	2.5	2.5
Metoprolol	202	2.5	2.5
Meclizine Hcl 12.5Mg	11	2.5	2.5
Meclizine Hcl 25Mg	11	2.5	2.5
Meclizine Hcl 12.5 Mg	11	2.5	2.5
Meclizine Hcl 25 Mg	11	2.5	2.5
Biotin	25	2.4	2.4
Metformin	279	2.4	2.4
Aspirin	415	2.4	2.4
Meclizine	13	2.4	2.4
Folic Acid	195	2.4	2.4
Meloxicam	46	2.4	2.4
Allopurinol	123	2.4	2.4
Guaifenesin	24	2.4	2.4
Terbinafine Hydrochloride	7	2.4	2.4
Terazosin Hydrochloride	7	2.4	2.4
Carisoprodol	15	2.4	2.4
Metformin Er 500 Mg	232	2.4	2.4
Metformin Er 750 Mg	232	2.4	2.4
Spironolactone	109	2.4	2.4
Aspirin 81 Mg	387	2.4	2.4
Ursodiol	17	2.4	2.4
Tolterodine Tartrate	7	2.4	2.4
Aspirin 325 Mg	386	2.4	2.4
Erythropoietin	16	2.4	2.4
Methocarbamol Tablets	13	2.4	2.4
Niacin	9	2.4	2.4
Sucralfate Oral	11	2.4	2.4
Levothyroxine Sodium	238	2.4	2.4
Sucralfate Oral Suspension	11	2.3	2.4
Riociguat	25	2.3	2.3
Trazodone Hydrochloride	12	2.3	2.3
Nintedanib	24	2.3	2.3
Fish Oil	68	2.3	2.3
Macitentan	52	2.3	2.3
Omeprazole	253	2.3	2.3
Glyburide	18	2.3	2.3
Losartan	128	2.3	2.3
Sertraline Hydrochloride	87	2.2	2.3
Senna Leaf	17	2.2	2.2
Sennosides	22	2.2	2.2
Valsartan And Hydrochlorothiazide	10	2.2	2.2
Simvastatin	181	2.2	2.2
Minoxidil Foam 5% (Womens)	24	2.2	2.2
Heparin Sodium	10	2.2	2.2
Indapamide	13	2.2	2.2
Insulin Degludec	17	2.2	2.2
Ibuprofen Capsule	143	2.2	2.2
Ibuprofen Tablet, Film Coated	143	2.2	2.2
Ibupfrofen	143	2.2	2.2
Ibuprofen Tablets Usp, 200Mg	143	2.2	2.2
Ibuprofen Oral	143	2.2	2.2
Ibuprofen Capsules 200 Mg	143	2.2	2.2
Ibuprofen 200 Mg	143	2.2	2.2
Ibuprofen 200Mg	143	2.2	2.2
Sotalol Hydrochloride	12	2.2	2.2
Erlotinib Hydrochloride	9	2.2	2.2
Sennosides 8.6 Mg Tablets	15	2.2	2.2
Zolpidem Tartrate	96	2.2	2.2
Amoxicillin	54	2.2	2.2
Icosapent Ethyl	6	2.1	2.1
Celecoxib	92	2.1	2.1
Lovastatin	18	2.1	2.1
Calcium, Magnesium, Potassium, And Sodium Oxybates	6	2.1	2.1
Rizatriptan Benzoate	7	2.1	2.1
Tofacitinib Citrate	9	2.1	2.1
Adalimumab-Adaz	36	2.1	2.1
Nebivolol Hydrochloride	23	2.1	2.1
Lisinopril	205	2.1	2.1
Fluticasone Propionate	87	2.1	2.1
Infliximab	145	2.0	2.0
Metoroprolol Tartrate	44	2.0	2.0
Bosutinib	6	2.0	2.0
Fexofenadine	11	2.0	2.0
Atenolol	88	2.0	2.0
Losartan Potassium	52	2.0	2.0
Multivitamin	33	2.0	2.0
Progesterone	15	2.0	2.0
Liraglutide	32	2.0	2.0
Sildenafil Powder,	23	2.0	2.0
Fexofenadine Hydrochloride	14	2.0	2.0
Oxycodone And Acetaminophen	15	2.0	2.0
Famotidine	75	2.0	2.0
Estrogens, Conjugated	38	2.0	2.0
Gabapentin	229	1.9	1.9
Glecaprevir And Pibrentasvir	7	1.9	1.9
Conjugated Estrogens	37	1.9	1.9
Amlodipine Besylate And Valsartan	7	1.9	1.9
Eszopiclone	16	1.9	1.9
Mycophenilic Acid	13	1.9	1.9
Baricitinib	6	1.9	1.9
Suvorexant	8	1.9	1.9
Varenicline Tartrate	49	1.9	1.9
Azelastine	11	1.9	1.9
Acyclovir	68	1.8	1.8
Everolimus Tablets	10	1.8	1.8
Bosentan	30	1.8	1.8
Glimepiride	23	1.8	1.8
Sildenafil	34	1.8	1.8
Diroximel Fumarate	7	1.8	1.8
Fluticasone Furoate And Vilanterol Trifenatate	21	1.8	1.8
Sildenafil Citrate	74	1.8	1.8
Amantadine	9	1.8	1.8
Mometasone Furoate And Formoterol Fumarate Dihydrate	9	1.8	1.8
Dofetilide	6	1.7	1.7
Instalax Polyethylene Glycol 3350	7	1.7	1.7
Polyethylene Glycol 400	7	1.7	1.7
Oxycodone Hydrochloride And Acetaminophen	54	1.7	1.7
Donepezil Hydrochloride	20	1.7	1.7
Dasatinib	20	1.6	1.6
Minoxidil	24	1.6	1.6
Polyethylene Glycol 3350	50	1.6	1.6
Cladribine	5	1.6	1.6
Tofacitinib	95	1.6	1.6
Sodium Oxybate	34	1.6	1.6
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	16	1.6	1.6
Entecavir	6	1.6	1.6
Lanreotide Acetate	4	1.6	1.6
Naproxen Sodium Tablet	27	1.6	1.6
Ibrutinib	40	1.5	1.5
Oral Semaglutide	36	1.5	1.5
Dronedarone	5	1.5	1.5
Insulin Glargine	119	1.5	1.5
Oxycodone	90	1.5	1.5
Ozanimod Hydrochloride	4	1.5	1.5
Empagliflozin	32	1.4	1.4
Naltrexone Hydrochloride And Bupropion Hydrochloride	4	1.4	1.4
Fesoterodine Fumarate	5	1.4	1.4
Brinzolamide	4	1.4	1.4
Ravulizumab	6	1.4	1.4
Hydrocodone Bitartrate And Acetaminophen	25	1.4	1.4
Sevelamer Carbonate	5	1.3	1.3
Canagliflozin	13	1.3	1.3
Ixekizumab	16	1.3	1.3
Imatinib Mesylate	12	1.3	1.3
Tafamidis	5	1.3	1.3
Ranitidine Hydrochloride	23	1.3	1.3
Ustekinumab	43	1.3	1.3
Exenatide	22	1.3	1.3
Methylphenidate	12	1.3	1.3
Denosumab	83	1.3	1.3
Emicizumab	5	1.2	1.2
Asfotase Alfa	4	1.2	1.2
Abatacept	55	1.2	1.2
Venetoclax	24	1.2	1.2
Secukinumab	62	1.2	1.2
Sacubitril And Valsartan	44	1.2	1.2
Loratadine And Pseudoephedrine Sulfate	3	1.1	1.1
Romosozumab-Aqqg	5	1.1	1.1
Treprostinil	45	1.1	1.1
Paricalcitol	5	1.1	1.1
Ambrisentan	44	1.1	1.1
Interferon Beta-1A	66	1.0	1.0
Apalutamide	4	1.0	1.0
Conjugated Estrogens And Medroxyprogesterone Acetate	7	0.9	0.9
Abiraterone	4	0.9	0.9
Abiraterone Acetate	12	0.9	0.9
Ixazomib	8	0.8	0.8
Dimethyl Fumarate	34	0.8	0.8
Leuprolide Acetate	20	0.8	0.8
Aflibercept	8	0.8	0.8
Drospirenone And Ethinyl Estradiol	10	0.7	0.7
Guselkumab	8	0.7	0.7
Enzalutamide	13	0.7	0.7
Abaloparatide	6	0.6	0.6
Dulaglutide	18	0.6	0.6
Orlistat	5	0.6	0.6
Pirfenidone	7	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.