Reaction

Device Adhesion Issue reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 15,010 reports · 288 co-occurring drugs

As of the last recalculation, Device Adhesion Issue appears in 15,010 FAERS reports alongside 288 co-occurring drug terms. The strongest observed disproportionality signal is PEGFILGRASTIM (PRR 751.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Pegfilgrastim	11,734	751.9	853.9
Estradiol And Levonorgestrel	245	169.9	193.2
Estradiol Gel 0.1%	1,161	38.5	39.5
Estradiol,	1,161	38.5	39.5
Estradiol Transdermal	1,161	38.5	39.5
Rotigotine	368	36.1	37.1
Estradiol	1,309	22.9	23.3
Methylphenidate	304	14.8	15.0
Ketamine Hydrochloride	26	7.4	7.4
Pegfilgrastim-Cbqv	7	7.3	7.3
Norelgestromin And Ethinyl Estradiol	9	6.8	6.8
Fentanyl	405	5.8	5.9
Lidocaine Hydrochloride Anhydrous	26	5.4	5.5
Asenapine	3	4.7	4.7
Progesterone	56	3.4	3.4
Ketoprofen	29	3.1	3.1
Amitriptyline Hydrochloride	26	2.1	2.1
Gaunfacine	5	1.9	1.9
Guanfacine Hydrochloride	6	1.8	1.8
Sotatercept-Csrk	6	1.7	1.7
Diclofenac Epolamine	5	1.6	1.6
Treprostinil	134	1.5	1.5
Guanfacine	7	1.2	1.2
Clonidine	44	1.2	1.2
Lidocaine 4% Maximum Strength 24 Hr	4	1.2	1.2
Lidocaine Patch	4	1.2	1.2
Clonidine Hydrochloride	4	1.0	1.0
Macitentan	48	1.0	1.0
Foscarbidopa/Foslevodopa	5	0.9	0.9
0Xygen	33	0.9	0.9
Oxygen	33	0.9	0.9
Sacituzumab Govitecan	3	0.9	0.9
Sildenafil	38	0.9	0.9
Simethicone	3	0.9	0.9
Sildenafil Powder,	22	0.9	0.9
Riociguat	19	0.8	0.8
Lidocaine Hydrochloride	35	0.8	0.8
Levodopa	7	0.8	0.8
Calcium Carbonate, Simethicone	3	0.8	0.8
Pertuzumab	13	0.7	0.7
Ropinirole	7	0.6	0.6
Cetirizine Hcl	4	0.6	0.6
Tadalafil	43	0.6	0.6
Buprenorphine	39	0.6	0.6
Oxybutynin	12	0.6	0.6
Lidocaine Patch 5%	3	0.5	0.5
Doxorubicin	34	0.5	0.5
Sodium Chloride Tablet	28	0.5	0.5
Sodium Chloride Tablets	28	0.5	0.5
Promethazine Hydrochloride	7	0.5	0.5
Rivastigmine	7	0.5	0.5
Buspirone Hydrochloride	4	0.5	0.5
Sildenafil Citrate	46	0.5	0.5
Rasagiline Mesylate	4	0.5	0.5
Sodium Chloride	28	0.5	0.5
Ambrisentan	44	0.5	0.5
Docetaxel Anhydrous	23	0.5	0.5
Docetaxel	23	0.5	0.5
Melatonin	18	0.5	0.5
Amlodipine Besylate And Benazepril Hydrochloride	3	0.5	0.5
Cyclophosphamide Injection, Solution	56	0.4	0.4
Cyclophosphamide	56	0.4	0.4
Cyclophosphamide For Injection	56	0.4	0.4
Doxorubicin Hydrochloride	10	0.4	0.4
Testosterone	7	0.4	0.4
Carboplatin	34	0.4	0.4
Lidocaine 4%	14	0.4	0.4
Lidocaine	14	0.3	0.3
Selexipag	6	0.3	0.3
Hydroxyzine Hydrochloride	3	0.3	0.3
Hydroxyzine Hydrochloride Oral	3	0.3	0.3
Bumetanide	6	0.3	0.3
Methylphenidate Hydrochloride	13	0.3	0.3
Diphenoxylate Hydrochloride And Atropine Sulfate	3	0.3	0.3
Torsemide	7	0.3	0.3
Sucralfate Oral	3	0.3	0.3
Sucralfate Oral Suspension	3	0.3	0.3
Trastuzumab	14	0.3	0.3
Lidocaine, Menthol	10	0.3	0.3
Fluorouracil Cream, 0.5%	15	0.3	0.3
Fluorouracil	15	0.3	0.3
Carbidopa And Levodopa	9	0.3	0.3
Lidicaine	9	0.3	0.3
Burn Relief	9	0.3	0.3
Lidocaine Hydrochloride And Epinephrine	9	0.3	0.3
Gabapentin	65	0.2	0.2
Oxaliplatin	13	0.2	0.2
Vincristine Sulfate	5	0.2	0.2
Lidocaine Hydrochloride And Epinephrine Bitartrate	9	0.2	0.2
Tizanidine Hydrochloride	3	0.2	0.2
Fluticasone Propionate Nasal	5	0.2	0.2
Magnesium	13	0.2	0.2
Digoxin	11	0.2	0.2
Fluoxetine	10	0.2	0.2
Etonogestrel	7	0.2	0.2
Loratadine Oral	7	0.2	0.2
Atorvastatin Calcium, Film Coated	10	0.2	0.2
Potassium Chloride, Dextrose Monohydrate	13	0.2	0.2
Potassium Chloride Oral	13	0.2	0.2
Potassium Chloride	16	0.2	0.2
Potassium Chloride Extended-Release	13	0.2	0.2
Fexofenadine Hydrochloride	3	0.2	0.2
Fluoxetine Hydrochloride	17	0.2	0.2
Methocarbamol	3	0.2	0.2
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	4	0.2	0.2
Oxycodone Hydrochloride And Acetaminophen	13	0.2	0.2
Warfarin Sodium	6	0.2	0.2
Triamcinolone Acetonide Ointment Usp, 0.05%	3	0.2	0.2
Atomoxetine Hydrochloride	3	0.2	0.2
Hydroxyzine	6	0.2	0.2
Sucralfate	3	0.2	0.2
Ondansetron Hydrochloride	15	0.2	0.2
Zinc	3	0.2	0.2
Paclitaxel (Aibumin-Bound)	10	0.2	0.2
Zinc Chloride	3	0.2	0.2
Spironolactone	17	0.2	0.2
Sumatriptan Succinate	3	0.2	0.2
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	19	0.2	0.2
Fluticasone Propionate	15	0.2	0.2
Zinc Gluconate	3	0.2	0.2
Loratadine Tablet	6	0.2	0.2
Loratadine	12	0.2	0.2
Bupropion Hydrochloride	11	0.2	0.2
Famotidine	13	0.2	0.2
Rituximab	23	0.1	0.1
Sumatriptan	4	0.1	0.1
Cetirizine Hydrochloride	17	0.1	0.1
Gemcitabine	4	0.1	0.1
Paclitaxel	10	0.1	0.1
Nicotine	4	0.1	0.1
Triamcinolone Acetonide	3	0.1	0.1
Metoprolol Succinate Er Tablets	6	0.1	0.1
Fluticasone Propionate And Salmeterol	4	0.1	0.1
Metoprolol Succinate	8	0.1	0.1
Levothyroxine Sodium	29	0.1	0.1
Lisdexamfetamine Dimesylate	3	0.1	0.1
Montelukast Sodium	11	0.1	0.1
Nebivolol Hydrochloride	3	0.1	0.1
Furosemide	36	0.1	0.1
Clonazepam	14	0.1	0.1
Sertraline Hydrochloride	10	0.1	0.1
Diazepam	10	0.1	0.1
Etoposide	6	0.1	0.1
Pantoprazole Sodium In 0.9% Sodium Chloride	5	0.1	0.1
Pantoprazole Sodium Injection	5	0.1	0.1
Multivitamin	4	0.1	0.1
Filgrastim	3	0.1	0.1
Diazepam Oral Solution (Concentrate)	7	0.1	0.1
Diazepam Oral	7	0.1	0.1
Warfarin	10	0.1	0.1
Ergocalciferol	30	0.1	0.1
Cisplatin	6	0.1	0.1
Gemcitabine Hydrochloride	4	0.1	0.1
Iron	5	0.1	0.1
Oxycodone	14	0.1	0.1
Empagliflozin	5	0.1	0.1
Enalapril	4	0.1	0.1
Magnesium Oxide	3	0.1	0.1
Ibuprofen Tablets, Coated	3	0.1	0.1
Acetaminophen	32	0.1	0.1
Ibuprofen Sodium	3	0.1	0.1
Levothyroxine Sodium Anhydrous	7	0.1	0.1
Copper	3	0.1	0.1
Docusate Sodium	4	0.1	0.1
Duloxetine Hydrochloride	13	0.1	0.1
Escitslopram	4	0.1	0.1
Losartan	12	0.1	0.1
Somatropin	5	0.1	0.1
Bupropion	3	0.1	0.1
Pantoprazole Sodium	10	0.1	0.1
Loperamide Hydrochloride	3	0.1	0.1
Albuterol Sulfate	20	0.1	0.1
Mycophenolate Mofetil	9	0.1	0.1
Mycophenolate Mofetil Hydrochloride	9	0.1	0.1
Ibuprofen Capsule	13	0.1	0.1
Ibuprofen Tablet, Film Coated	13	0.1	0.1
Ibuprofen Tablet, Film-Coated	13	0.1	0.1
Ibupfrofen	13	0.1	0.1
Ibuprofen Tablets Usp, 200Mg	13	0.1	0.1
Ibuprofen Oral	13	0.1	0.1
Ibuprofen Capsules 200 Mg	13	0.1	0.1
Ibuprofen 200 Mg	13	0.1	0.1
Ibuprofen 200Mg	13	0.1	0.1
Alprazolam	13	0.1	0.1
Cyclobenzaprine	3	0.1	0.1
Ferrous Sulfate	3	0.1	0.1
Latanoprost	3	0.1	0.1
Omeprazole Magnesium	27	0.1	0.1
Ibuprofen	16	0.1	0.1
Baclofen	5	0.1	0.1
Metoprolol Tartrate	16	0.1	0.1
Metoprolol Tartrate Injection	11	0.1	0.1
Escitalopram	8	0.1	0.1
Naproxen Sodium Tablet	3	0.1	0.1
Atorvastatin Calcium	14	0.1	0.1
Hydrocortisone	5	0.1	0.1
Ruxolitinib	4	0.1	0.1
Escitalopram Oxalate	4	0.1	0.1
Metoclopramide	3	0.1	0.1
Metoprolol	14	0.1	0.1
Vitamin C	5	0.1	0.1
Diphenhydramine Hydrochloride	9	0.1	0.1
Morphine	4	0.1	0.1
Ezetimibe	4	0.1	0.1
Zolpidem Tartrate	7	0.1	0.1
Omeprazole	18	0.1	0.1
Cetirizine	4	0.1	0.1
Risankizumab-Rzaa	4	0.1	0.1
Naproxen Sodium	7	0.1	0.1
Montelukast	4	0.1	0.1
Simvastatin	12	0.1	0.1
Pantoprazole	12	0.1	0.1
Prednisone	24	0.1	0.1
Epinephrine	3	0.1	0.1
Ondansetron	5	0.1	0.1
Ondansetron Tablets	5	0.1	0.1
Metoroprolol Tartrate	3	0.1	0.1
Anti-Itch	3	0.1	0.1
Anti-Pruritic	3	0.1	0.1
Antipruritic (Anti-Itch)	3	0.1	0.1
Cool Relief Gel With Aloe	3	0.1	0.1
Drs. Hydrocortisone	3	0.1	0.1
Hydrocortisone Continuous Spray	3	0.1	0.1
Hydrocortisone Spray	3	0.1	0.1
Anti-Itch Cream	3	0.1	0.1
Hydrocortisone Lotion	3	0.1	0.1
Hydrocortisone Cream 1%	3	0.1	0.1
Hydrocortisone Cream 1/2%	3	0.1	0.1
Hydrocortisone 1%	3	0.1	0.1
Hydrocortisone Cream	3	0.1	0.1
Lorazepam	8	0.1	0.1
Hydroxychloroquine Sulfate	4	0.1	0.1
Duloxetine	3	0.1	0.1
Evolocumab	7	0.1	0.1
Polyethylene Glycol 3350	4	0.1	0.1
Hydrocortisone Acetate	3	0.1	0.1
Oxycodone Hydrochloride	9	0.1	0.1
Pregabalin	11	0.1	0.1
Metoclopramide Hydrochloride	3	0.1	0.1
Rosuvastatin	8	0.1	0.1
Losartan Potassium	3	0.1	0.1
Pembrolizumab	4	0.1	0.1
Lamotrigine	5	0.1	0.1
Citalopram Hydrobromide	4	0.1	0.1
Carvedilol	5	0.1	0.1
Citalopram	5	0.1	0.1
Sulfamethoxazole And Trimethoprim	3	0.0	0.0
Rivaroxaban	7	0.0	0.0
Fish Oil	3	0.0	0.0
Topiramate	3	0.0	0.0
Allopurinol	5	0.0	0.0
Acetaminophen Tablet Extended Release	8	0.0	0.0
Pain Reliever	8	0.0	0.0
Acetaminophen 500Mg	8	0.0	0.0
Aspirin	17	0.0	0.0
Aspirin 325 Mg	16	0.0	0.0
Aspirin 81 Mg	16	0.0	0.0
Celecoxib	4	0.0	0.0
Venlafaxine Hydrochloride	4	0.0	0.0
Alendronate Sodium	3	0.0	0.0
Amlodipine	8	0.0	0.0
Olanzapine	3	0.0	0.0
Folic Acid	7	0.0	0.0
Metformin	10	0.0	0.0
Hydrochlorothiazide	4	0.0	0.0
Diclofenac Sodium	4	0.0	0.0
Metformin Er 500 Mg	8	0.0	0.0
Metformin Er 750 Mg	8	0.0	0.0
Lisinopril	8	0.0	0.0
Sertraline	3	0.0	0.0
Albuterol	3	0.0	0.0
Morphine Sulfate	3	0.0	0.0
Aripiprazole	3	0.0	0.0
Lansoprazole	4	0.0	0.0
Prednisolone	4	0.0	0.0
Prednisolone Oral	4	0.0	0.0
Prednisolone Oral Solution	4	0.0	0.0
Esomeprazole Magnesium	5	0.0	0.0
Quetiapine	4	0.0	0.0
Amlodipine Besylate	3	0.0	0.0
Calcium	3	0.0	0.0
Insulin Glargine	5	0.0	0.0
Methotrexate	7	0.0	0.0
Clopidogrel	3	0.0	0.0
Methotrexate Sodium	7	0.0	0.0
Dexamethasone 1.5 Mg	4	0.0	0.0
Dexamethasone	4	0.0	0.0
Adalimumab	8	0.0	0.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.