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Which drugs are most reported with Complication of device removal?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 16,741 reports · 423 co-occurring drugs

As of the last recalculation, Complication Of Device Removal appears in 16,741 FAERS reports alongside 423 co-occurring drug terms. The strongest observed disproportionality signal is COPPER (PRR 714.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Copper	10,000	714.8	932.1
Etonogestrel	3,308	107.2	115.1
Levonorgestrel	2,642	19.2	19.4
Histrelin Acetate	13	18.4	18.6
Estradiol Acetate	5	8.1	8.2
12%Azelaic Acid	3	4.7	4.7
14%Azelaic Acid	3	4.7	4.7
Norethindrone Acetate And Ethinyl Estradiol, Ethinyl Estradiol And Ferrous Fumarate	12	4.7	4.7
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, And Amphetamine Sulfate	127	4.5	4.5
Azelaic Acid	3	3.9	4.0
Norethindrone Acetate And Ethinyl Estradiol And Ferrous Fumarate	8	3.9	3.9
Phentermine Hydrochloride	20	3.9	3.9
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate And Amphetamine Aspartate	127	3.8	3.8
Bupropion Hydrochloride (Xl)	8	3.6	3.6
Tretinoin	18	2.8	2.8
Norgestimate And Ethinyl Estradiol	10	2.7	2.7
Naratriptan	3	2.7	2.7
Misoprostol	20	2.6	2.6
Iloperidone	3	2.5	2.5
Ammonium Lactate	4	2.3	2.3
Succinylcholine	3	2.3	2.3
Etonogestrel And Ethinyl Estradiol	37	2.1	2.1
Dextroamphetamine	6	2.0	2.0
Desogestrel And Ethinyl Estradiol	5	1.9	1.9
Thyroid, Porcine	16	1.9	1.9
Estradiol And Levonorgestrel	3	1.8	1.8
Sumatriptan Succinate	37	1.8	1.8
Norethindrone	8	1.8	1.8
Levonorgestrel And Ethinyl Estradiol	4	1.7	1.7
Sumatriptan	53	1.7	1.7
Estradiol, Folliculinum, Oophorinum (Suis)	3	1.7	1.7
Norethindrone Acetate And Ethinyl Estradiol	3	1.6	1.6
Progesterone	29	1.6	1.6
Rizatriptan	8	1.6	1.6
Fluvoxamine Maleate	3	1.6	1.6
Povidone-Iodine	5	1.5	1.5
Hydroxyzine Pamoate	4	1.4	1.4
Bupropion Hydrochloride	102	1.3	1.3
Nitrofurantoin Monohydrate/Macrocrystalline	6	1.3	1.3
Lisdexamfetamine Dimesylate	33	1.2	1.2
Escitalopram	138	1.2	1.2
Rizatriptan Benzoate	10	1.2	1.2
Prazosin	6	1.2	1.2
Valacyclovir Hydrochloride	68	1.2	1.2
Bupropion	43	1.2	1.2
Valacyclovir	38	1.1	1.1
Ibuprofen And Diphenhydramine Citrate	21	1.1	1.1
Metaxalone	3	1.1	1.1
Fluoxetine Hydrochloride	113	1.1	1.1
Fluoxetine	59	1.1	1.1
Sertraline Hydrochloride	102	1.1	1.1
Iodine	3	1.1	1.1
Acetazolamide	5	1.0	1.0
Clindamycin Hydrochloride	3	1.0	1.0
Acetazolamide Sodium	5	1.0	1.0
Escitslopram	44	0.9	0.9
Labetalol	10	0.9	0.9
Dexmethylphenidate Hydrochloride	3	0.9	0.9
Zolmitriptan	5	0.9	0.9
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	34	0.8	0.8
Guanfacine Hydrochloride	3	0.8	0.8
Ubrogepant	4	0.8	0.8
Butalbital, Acetaminophen, And Caffeine	7	0.8	0.8
Vilazodone Hydrochloride	6	0.8	0.8
Topiramate	60	0.8	0.8
Iron	43	0.8	0.8
Albuterol	77	0.8	0.8
Methimazole	5	0.8	0.8
Medroxyprogesterone Acetate	31	0.8	0.8
Escitalopram Oxalate	45	0.8	0.8
Spironolactone	85	0.8	0.8
Methocarbamol Tablets	10	0.7	0.7
Methocarbamol	13	0.7	0.7
Lamotirigine	41	0.7	0.7
Lamotrigine Extended-Release	41	0.7	0.7
Lamotrigine Chewable Dispersible	41	0.7	0.7
Propranolol Hydrochloride	41	0.7	0.7
Albuterol Sulfate	169	0.7	0.7
Lamotrigine	73	0.7	0.7
Hydroxyzine	26	0.7	0.7
Cariprazine	5	0.7	0.7
Cefdinir	4	0.6	0.6
Nortriptyline Hydrochloride	3	0.6	0.6
Trazodone Hydrochloride	8	0.6	0.6
Fluticasone Propionate	65	0.6	0.6
Ibuprofen Capsule	100	0.6	0.6
Ibuprofen Tablet, Film Coated	100	0.6	0.6
Ibuprofen Tablet, Film-Coated	100	0.6	0.6
Ibupfrofen	100	0.6	0.6
Ibuprofen Tablets Usp, 200Mg	100	0.6	0.6
Ibuprofen Oral	100	0.6	0.6
Ibuprofen Capsules 200 Mg	100	0.6	0.6
Ibuprofen 200 Mg	100	0.6	0.6
Ibuprofen 200Mg	100	0.6	0.6
Sertraline	57	0.6	0.6
Cetirizine Hydrochloride	80	0.6	0.6
Biotin	15	0.6	0.6
Magnesium Sulfate In Water For	6	0.6	0.6
Piperacillin And Tazobactam	6	0.6	0.6
Magnesium Sulfate Heptahydrate	6	0.6	0.6
Magnesium Sulfate	6	0.6	0.6
Liothyronine Sodium	4	0.6	0.6
Ibuprofen	125	0.6	0.6
Hydroxyzine Hydrochloride	6	0.6	0.6
Hydroxyzine Hydrochloride Oral	6	0.6	0.6
Buspirone Hydrochloride	5	0.6	0.6
Loratadine Oral	22	0.6	0.6
Lisdexamfetamine	3	0.6	0.6
Azelastine	8	0.6	0.6
Desvenlafaxine Succinate	12	0.6	0.6
Fluticasone Propionate And Salmeterol Xinafoate	26	0.5	0.5
Citalopram	59	0.5	0.5
Eletriptan Hydrobromide	3	0.5	0.5
Montelukast Sodium	52	0.5	0.5
Clindamycin Phosphate	14	0.5	0.5
Doxycycline Hyclate	28	0.5	0.5
Hydrochlorothiazide	60	0.5	0.5
Acetaminophen, Aspirin (Nsaid) And Caffeine	7	0.5	0.5
Doxycycline	28	0.5	0.5
Loratadine Tablet	22	0.5	0.5
Loratadine	44	0.5	0.5
Estradiol	35	0.5	0.5
Cyclobenzaprine	20	0.5	0.5
Estradiol Gel 0.1%	18	0.5	0.5
Estradiol,	18	0.5	0.5
Estradiol Transdermal	18	0.5	0.5
Metronidazole	25	0.5	0.5
Clindamycin	11	0.5	0.5
Levothyroxine Sodium	122	0.5	0.5
Guanfacine	3	0.5	0.5
Venlafaxine Hydrochloride	50	0.5	0.5
Alprazolam	78	0.5	0.5
Metformin Er 500 Mg	114	0.5	0.5
Metformin Er 750 Mg	114	0.5	0.5
Piperacillin Sodium And Tazobactam Sodium	7	0.4	0.4
Fish Oil	32	0.4	0.4
Doxyclycline Hyclate	6	0.4	0.4
Naltrexone Hydrochloride And Bupropion Hydrochloride	3	0.4	0.4
Losartan Potassium And Hydrochlorothiazide	4	0.4	0.4
Testosterone	8	0.4	0.4
Ferrous Sulfate	17	0.4	0.4
Venlafaxine	24	0.4	0.4
Cyclobenzaprine Hydrochloride	3	0.4	0.4
Acetaminophen, Aspirin, And Caffeine	7	0.4	0.4
Lidicaine	16	0.4	0.4
Burn Relief	16	0.4	0.4
Lidocaine Hydrochloride And Epinephrine	16	0.4	0.4
Citalopram Hydrobromide	35	0.4	0.4
Metformin	117	0.4	0.4
Lidocaine, Menthol	16	0.4	0.4
Lidocaine Hydrochloride And Epinephrine Bitartrate	17	0.4	0.4
Lithium	8	0.4	0.4
Lithium Bromatum	8	0.4	0.4
Docusate Sodium - Sennosides	10	0.4	0.4
Epoprostenol	4	0.4	0.4
Nitrofurantoin (Monohydrate/Macrocrystals)	5	0.4	0.4
Nitrofurantoin Monohydrate/Macrocrystals	5	0.4	0.4
Triamcinolone Acetonide Ointment Usp, 0.05%	7	0.4	0.4
Lidocaine Hydrochloride	18	0.4	0.4
Magnesium Hydroxide	4	0.4	0.4
Fluticasone Propionate Nasal	9	0.4	0.4
Lithium Carbonate	5	0.4	0.4
Melatonin	16	0.4	0.4
Lidocaine 4%	16	0.4	0.4
Naltrexone	9	0.4	0.4
Ciprofloxacin Hydrochloride And Hydrocortisone	6	0.4	0.4
Lurasidone Hydrochloride	6	0.4	0.4
Duloxetine	20	0.4	0.4
Duloxetine Hydrochloride	54	0.4	0.4
Oral Semaglutide	21	0.4	0.4
Aripiprazole	35	0.4	0.4
Zinc	7	0.4	0.4
Zinc Chloride	7	0.4	0.4
Dapsone	3	0.3	0.3
Dicyclomine Hydrochloride	4	0.3	0.3
Lidocaine	16	0.3	0.3
Methylphenidate Hydrochloride	16	0.3	0.3
Zinc Gluconate	7	0.3	0.3
Nystatin Ointment	7	0.3	0.3
Nystatin Cream	7	0.3	0.3
Lisinopril	82	0.3	0.3
Fremanezumab-Vfrm	3	0.3	0.3
Calcium	39	0.3	0.3
Vitamin C	24	0.3	0.3
Chlorthalidone	3	0.3	0.3
Minocycline	3	0.3	0.3
Losartan	45	0.3	0.3
Nystatin	7	0.3	0.3
Lorazepam	46	0.3	0.3
Paroxetine Hydrochloride	23	0.3	0.3
Tizanidine	6	0.3	0.3
Levocetirizine Dihydrochloride	6	0.3	0.3
Epinephrine	16	0.3	0.3
Nitrofurantoin	4	0.3	0.3
Fluconazole	17	0.3	0.3
Oxybutynin	7	0.3	0.3
Montelukast	20	0.3	0.3
Divalproex Sodium	11	0.3	0.3
Clonazepam	38	0.3	0.3
Eszopiclone	6	0.3	0.3
Vortioxetine	4	0.3	0.3
Ergocalciferol	90	0.3	0.3
Magnesium	19	0.3	0.3
Metronidazole Topical	11	0.3	0.3
Triamcinolone Acetonide	7	0.3	0.3
Piperacillin Sodium,Tazobactam Sodium	6	0.3	0.3
Multivitamin	11	0.3	0.3
Levothyroxine Sodium Anhydrous	22	0.3	0.3
Mometasone	4	0.3	0.3
Aripiprazole Oral	9	0.3	0.3
Aripiprazole Orally Disintegrating	9	0.3	0.3
Promethazine Hydrochloride	4	0.3	0.3
Ascorbic Acid	5	0.3	0.3
Riociguat	7	0.3	0.3
Cyanocobalamin	7	0.3	0.3
Interferon Beta-1A	41	0.3	0.3
Ziprasidone Mesylate	3	0.3	0.3
Paroxetine Hydrochloride Hemihydrate	7	0.3	0.3
Acyclovir	24	0.3	0.3
Buprenorphine Hydrochloride, Naloxone Hydrochloride	5	0.3	0.3
Methylphenidate	6	0.3	0.3
Treprostinil	26	0.3	0.3
Meloxicam	12	0.3	0.3
Paroxetine	7	0.3	0.3
Omeprazole	69	0.2	0.2
Ropinirole	3	0.2	0.2
Clonidine	10	0.2	0.2
Zolpidem Tartrate	26	0.2	0.2
Naproxen	15	0.2	0.2
Nifedipine	9	0.2	0.2
Docusate Sodium	11	0.2	0.2
Cetiirizine	8	0.2	0.2
Metoprolol Tartrate Injection	36	0.2	0.2
Famotidine	22	0.2	0.2
Omeprazole Magnesium	84	0.2	0.2
Fexofenadine Hydrochloride	4	0.2	0.2
Fexofenadine	3	0.2	0.2
Brexpiprazole	3	0.2	0.2
Budesonide And Formoterol Fumarate Dihydrate	17	0.2	0.2
Naproxen Sodium	25	0.2	0.2
Ketoconazole	3	0.2	0.2
Amitriptyline Hydrochloride	3	0.2	0.2
Ziprasidone	3	0.2	0.2
Amlodipine	46	0.2	0.2
Brimonidine Tartrate	3	0.2	0.2
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	5	0.2	0.2
Ibuprofen Tablets, Coated	7	0.2	0.2
Propofol	6	0.2	0.2
Ibuprofen Sodium	7	0.2	0.2
Carisoprodol	3	0.2	0.2
Oxcarbazepine	5	0.2	0.2
Metoprolol	39	0.2	0.2
Pravastatin Sodium	3	0.2	0.2
Torsemide	5	0.2	0.2
Naproxen Sodium Tablet	8	0.2	0.2
Metoprolol Tartrate	41	0.2	0.2
Metoprolol Succinate Er Tablets	9	0.2	0.2
Cetirizine	11	0.2	0.2
Ciprofloxacin	13	0.2	0.2
Methadone	6	0.2	0.2
Sitagliptin And Metformin Hydrochloride	3	0.2	0.2
Fluticasone Furoate And Vilanterol Trifenatate	5	0.2	0.2
Cephalexin	3	0.2	0.2
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	22	0.2	0.2
Azithromycin Dihydrate	8	0.2	0.2
Drospirenone And Ethinyl Estradiol	6	0.2	0.2
Gabapentin	50	0.2	0.2
Ciprofloxacin Hydrochloride	13	0.2	0.2
Glipizide	8	0.2	0.2
Oxycodone Hydrochloride And Acetaminophen	13	0.2	0.2
Sodium Bicarbonate	3	0.2	0.2
Sodium Bicarbonate Injection,	3	0.2	0.2
Sodium Bicarbonate, Injection	3	0.2	0.2
Vitamin E	4	0.2	0.2
Galcanezumab-Gnlm	4	0.2	0.2
Mesalamine	7	0.2	0.2
Glyburide	3	0.2	0.2
Liraglutide	6	0.2	0.2
Adrenalinum	5	0.1	0.1
Mometasone Furoate	5	0.1	0.1
Baclofen	10	0.1	0.1
Metoprolol Succinate	10	0.1	0.1
Celecoxib	15	0.1	0.1
Linaclotide	3	0.1	0.1
Sildenafil Powder,	4	0.1	0.1
Hydroxychloroquine Sulfate	10	0.1	0.1
Lacosamide	4	0.1	0.1
Diazepam	13	0.1	0.1
Insulin Aspart	7	0.1	0.1
Levetiracetam	14	0.1	0.1
Empagliflozin	7	0.1	0.1
Vancomycin	6	0.1	0.1
Amlodipine Besylate	15	0.1	0.1
Isotretinoin	5	0.1	0.1
Hydrocortisone	9	0.1	0.1
Azithromycin	4	0.1	0.1
Mirtazapine	9	0.1	0.1
Ciprofolxacin	7	0.1	0.1
Ciprofloxacin Tablets	7	0.1	0.1
Atenolol	13	0.1	0.1
Rosuvastatin	20	0.1	0.1
Risedronate Sodium	3	0.1	0.1
Hydrocortisone Acetate	7	0.1	0.1
Azithromycin Monohydrate	4	0.1	0.1
Modafinil	3	0.1	0.1
Quetiapine	18	0.1	0.1
Diclofenac	8	0.1	0.1
Valsartan Oral	5	0.1	0.1
Ondansetron	10	0.1	0.1
Ondansetron Tablets	10	0.1	0.1
Vancomycin Hydrochloride	6	0.1	0.1
Onabotulinumtoxina	7	0.1	0.1
Pantoprazole	23	0.1	0.1
Anti-Itch	6	0.1	0.1
Anti-Pruritic	6	0.1	0.1
Antipruritic (Anti-Itch)	6	0.1	0.1
Cool Relief Gel With Aloe	6	0.1	0.1
Drs. Hydrocortisone	6	0.1	0.1
Hydrocortisone Continuous Spray	6	0.1	0.1
Hydrocortisone Spray	6	0.1	0.1
Anti-Itch Cream	6	0.1	0.1
Hydrocortisone Lotion	6	0.1	0.1
Hydrocortisone Cream 1%	6	0.1	0.1
Hydrocortisone Cream 1/2%	6	0.1	0.1
Hydrocortisone 1%	6	0.1	0.1
Calcium Carbonate	6	0.1	0.1
Hydrocortisone Cream	6	0.1	0.1
Losartan Potassium	7	0.1	0.1
Clarithromycin	3	0.1	0.1
Macitentan	6	0.1	0.1
Insulin Lispro	12	0.1	0.1
Sildenafil	5	0.1	0.1
Sildenafil Citrate	11	0.1	0.1
Antacid	4	0.1	0.1
Sodium Chloride Tablet	6	0.1	0.1
Sodium Chloride Tablets	6	0.1	0.1
Ondansetron Hydrochloride	10	0.1	0.1
Temazepam	3	0.1	0.1
Latanoprost	4	0.1	0.1
Nicotine Polacrilex	3	0.1	0.1
Acetaminophen	35	0.1	0.1
Sodium Chloride	6	0.1	0.1
Carbamazepine	5	0.1	0.1
Atorvastatin Calcium	18	0.1	0.1
Magnesium Oxide	3	0.1	0.1
Insulin	4	0.1	0.1
Rivaroxaban	15	0.1	0.1
Sulfamethoxazole And Trimethoprim	6	0.1	0.1
Dulaglutide	6	0.1	0.1
Glatiramer Acetate	4	0.1	0.1
Levofloxacin	4	0.1	0.1
Levofloxacin In 5% Dextrose	4	0.1	0.1
Amoxicillin	5	0.1	0.1
Letrozole	4	0.1	0.1
Warfarin Sodium	3	0.1	0.1
Esomeprazole	4	0.1	0.1
Esomeprazole Magnesium	15	0.1	0.1
Warfarin	8	0.1	0.1
Polyethylene Glycol 3350	6	0.1	0.1
Potassium Chloride	7	0.1	0.1
Risankizumab-Rzaa	5	0.1	0.1
Fentanyl	6	0.1	0.1
Tadalafil	6	0.1	0.1
Diclofenac Sodium	9	0.1	0.1
Aspirin 325 Mg	30	0.1	0.1
Aspirin 81 Mg	30	0.1	0.1
Valsartan	6	0.1	0.1
Ambrisentan	7	0.1	0.1
Simvastatin	14	0.1	0.1
Aspirin	30	0.1	0.1
Diphenhydramine Hydrochloride	9	0.1	0.1
Potassium Chloride, Dextrose Monohydrate	5	0.1	0.1
Potassium Chloride Oral	5	0.1	0.1
Potassium Chloride Extended-Release	5	0.1	0.1
Ezetimibe	4	0.1	0.1
Metformin Hydrochloride Tablets	3	0.1	0.1
Metformin Hydrochloride Extended-Release Tablets	3	0.1	0.1
Metformin Hydrochloride Tablet	3	0.1	0.1
Enoxaparin Sodium	3	0.1	0.1
Levetiracetam In Sodium Chloride	4	0.1	0.1
Levetiracetam Oral	4	0.1	0.1
Levetiracetam Injection	4	0.1	0.1
Metformin Hydrochloride	3	0.1	0.1
Prednisone	26	0.1	0.1
Alendronate Sodium	5	0.1	0.1
Folic Acid	12	0.1	0.1
Metoroprolol Tartrate	3	0.1	0.1
Risperidone	6	0.1	0.1
Diazepam Oral Solution (Concentrate)	4	0.1	0.1
Diazepam Oral	4	0.1	0.1
Lansoprazole	8	0.1	0.1
Carvedilol	6	0.1	0.1
Methylprednisolone	6	0.1	0.1
Tirzepatide	7	0.1	0.1
Ruxolitinib	3	0.1	0.1
Sitagliptin	3	0.1	0.1
Insulin Glargine	10	0.0	0.0
Morphine	3	0.0	0.0
Hydroxychloroquine	3	0.0	0.0
Acetaminophen Tablet Extended Release	10	0.0	0.0
Pain Reliever	10	0.0	0.0
Acetaminophen 500Mg	10	0.0	0.0
Sulfasalazine	3	0.0	0.0
Pregabalin	10	0.0	0.0
Azathioprine	3	0.0	0.0
Pantoprazole Sodium	5	0.0	0.0
Hydromorphone Hydrochloride	3	0.0	0.0
Buprenorphine	3	0.0	0.0
Oxycodone	6	0.0	0.0
Pegfilgrastim	3	0.0	0.0
Ranitidine	6	0.0	0.0
Furosemide	12	0.0	0.0
Cyclosporine	3	0.0	0.0
Teriparatide	3	0.0	0.0
Tacrolimus	4	0.0	0.0
Tacrolimus Ointment 0.1%	3	0.0	0.0
Tacrolimus Extended-Release Capsules	3	0.0	0.0
Methotrexate	8	0.0	0.0
Methotrexate Sodium	9	0.0	0.0
Clopidogrel	3	0.0	0.0
Dupilumab	5	0.0	0.0
Etanercept	6	0.0	0.0
Adalimumab	5	0.0	0.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.