Reaction

Abnormal Loss Of Weight reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,678 reports · 272 co-occurring drugs

As of the last recalculation, Abnormal Loss Of Weight appears in 6,678 FAERS reports alongside 272 co-occurring drug terms. The strongest observed disproportionality signal is NINTEDANIB (PRR 24.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Nintedanib	240	24.7	24.9
Diclofenac Potassium, Film Coated	59	22.0	22.2
Diclofenac Potassium Tablets	59	22.0	22.2
Canagliflozin	185	19.8	19.9
Diclofenac Potassium	59	17.2	17.2
Empagliflozin	218	10.4	10.4
Terbinafine Hydrochloride	29	10.2	10.2
Trimethoprim	36	9.6	9.6
Oral Semaglutide	192	8.4	8.4
Regorafenib	31	8.4	8.4
Felodipine Extended-Release Tablets	29	8.0	8.0
Felodipine	29	8.0	8.0
Ibuprofen And Diphenhydramine Citrate	58	7.8	7.8
Linagliptin	45	7.7	7.8
Tramadol Hydrochloride	84	7.0	7.0
Sitagliptin And Metformin Hydrochloride	45	6.5	6.6
Tiotropium Bromide	254	6.0	6.0
Lisdexamfetamine Dimesylate	60	5.7	5.7
Bisoprolol Fumarate	226	5.3	5.3
Sorafenib	35	5.3	5.3
Clopidogrel Bisulfate	168	5.2	5.2
Mesalamine	91	5.1	5.1
Ramipril	196	5.1	5.1
Naproxen	125	5.0	5.0
Riociguat	51	4.9	4.9
Guanfacine	12	4.8	4.8
Metformin Er 500 Mg	427	4.7	4.7
Metformin Er 750 Mg	427	4.7	4.7
Fluoxetine	98	4.6	4.6
Diphenoxylate Hydrochloride And Atropine Sulfate	20	4.6	4.6
Colchicine	38	4.5	4.5
Sotalol Hydrochloride	24	4.5	4.5
Sertraline	165	4.5	4.5
Finasteride	85	4.4	4.4
Budesonide	81	4.3	4.3
Olmesartan Medoxomil	49	4.3	4.3
Metformin	463	4.3	4.3
Ascorbic Acid	31	4.2	4.2
Topiramate	122	4.1	4.1
Diclofenac	111	4.1	4.1
Pancrelipase	50	4.1	4.1
Epoprostenol	17	4.1	4.1
Omeprazole	426	4.0	4.0
Digoxin	92	4.0	4.0
Methimazole	10	4.0	4.0
Simvastatin	307	4.0	4.0
Erythropoietin	26	4.0	4.0
Nebivolol	20	3.9	3.9
Rivaroxaban	254	3.9	3.9
Tiotropium Bromide Inhalation Spray	14	3.9	3.9
Glimepiride	48	3.9	3.9
Lovastatin	31	3.8	3.8
Candesartan	43	3.8	3.8
Liraglutide	58	3.7	3.7
Hydroxychloroquine Sulfate	106	3.7	3.7
Ciprofolxacin	83	3.6	3.6
Ciprofloxacin Tablets	83	3.6	3.6
Sitagliptin	83	3.6	3.6
Amitriptyline Hydrochloride	20	3.6	3.6
Fluticasone Propionate And Salmeterol Xinafoate	68	3.6	3.6
Omeprazole Magnesium	482	3.5	3.5
Prochlorperazine	31	3.5	3.5
Naproxen Sodium Tablet, Coated	15	3.5	3.5
Naproxen Sodium, Coated Tablets	15	3.5	3.5
Naproxen Sodium 220Mg	15	3.5	3.5
Leflunomide	113	3.4	3.4
Prochlorperazine Maleate	10	3.4	3.4
Dapagliflozin	34	3.4	3.4
Infliximab	229	3.3	3.4
Dabigatran Etexilate Mesylate	77	3.3	3.3
Diclofenac Sodium 1%	38	3.3	3.3
Diclofenac Sodium Topical	38	3.3	3.3
Diclofenac Sodium Topical Gel, 1%	38	3.3	3.3
Clopidogrel	206	3.3	3.3
Fenofibrate	37	3.3	3.3
Ticagrelor	33	3.2	3.2
Brinzolamide	9	3.2	3.2
Diazepam	124	3.2	3.2
Budesonide And Formoterol Fumarate Dihydrate	99	3.2	3.2
Lansoprazole	178	3.2	3.2
Mycophenilic Acid	21	3.2	3.2
Fentanyl Citrate	18	3.1	3.1
Umeclidinium	9	3.1	3.1
Sucralfate	24	3.1	3.1
Fluoxetine Hydrochloride	126	3.1	3.1
Dabigatran Etexilate	77	3.1	3.1
Cholestyramine	12	3.1	3.1
Glipizide	60	3.1	3.1
Naproxen Sodium	139	3.1	3.1
Trazodone Hydrochloride	15	3.0	3.0
Carisoprodol	18	2.9	2.9
Ciprofloxacin	86	2.9	2.9
Amlodipine	246	2.9	2.9
Ciprofloxacin Hydrochloride	90	2.9	2.9
Alendronate Sodium Tablet	17	2.9	2.9
Pramipexole	14	2.9	2.9
Nitrofurantoin	15	2.8	2.8
Vitamin C	83	2.8	2.8
Donepezil Hydrochloride	33	2.8	2.8
Docusate Sodium - Sennosides	29	2.8	2.8
Nitrofurantoin (Monohydrate/Macrocrystals)	15	2.8	2.8
Doxazosin	25	2.8	2.8
Allopurinol	138	2.8	2.8
Ibuprofen Capsule	174	2.8	2.8
Ibuprofen Tablet, Film Coated	174	2.8	2.8
Ibupfrofen	174	2.8	2.8
Ibuprofen Tablets Usp, 200Mg	174	2.8	2.8
Ibuprofen Oral	174	2.8	2.8
Ibuprofen Capsules 200 Mg	174	2.8	2.8
Ibuprofen 200 Mg	174	2.8	2.8
Ibuprofen 200Mg	174	2.8	2.8
Isosorbide Dinitrate	17	2.7	2.7
Diazepam Oral Solution (Concentrate)	77	2.7	2.7
Diazepam Oral	77	2.7	2.7
Diclofenac Sodium	129	2.7	2.7
Sildenafil	50	2.7	2.7
Nebivolol Hydrochloride	29	2.7	2.7
Eplerenone	11	2.7	2.7
Cyanocobalamin	28	2.7	2.7
Hydroxychloroquine	63	2.6	2.6
Benzonatate	14	2.6	2.6
Butalbital, Acetaminophen, And Caffeine	9	2.6	2.6
Aspirin	435	2.6	2.6
Aspirin 325 Mg	414	2.6	2.6
Aspirin 81 Mg	414	2.6	2.6
Bumetanide	22	2.6	2.6
Metoprolol Tartrate Injection	156	2.6	2.6
Macitentan	57	2.6	2.6
Esomeprazole	51	2.6	2.6
Ferrous Sulfate	41	2.6	2.6
Magnesium Hydroxide	11	2.5	2.5
Sildenafil Powder,	29	2.5	2.5
Quinine	7	2.5	2.5
0Xygen	40	2.5	2.5
Oxygen	40	2.5	2.5
Loperamide Hydrochloride And Dimethicone	26	2.5	2.5
Pioglitazone	35	2.5	2.5
Lisinopril	243	2.5	2.5
Rasagiline Mesylate	9	2.5	2.5
Doxazosin Mesylate	29	2.5	2.5
Warfarin	100	2.5	2.5
Indapamide	14	2.4	2.4
Tolterodine Tartrate	7	2.4	2.4
Furosemide	303	2.4	2.4
Selexipag	20	2.4	2.4
Niacin	9	2.4	2.4
Sucralfate Oral	11	2.4	2.4
Paliperidone	18	2.4	2.4
Sucralfate Oral Suspension	11	2.4	2.4
Ibuprofen	205	2.4	2.4
Amlodipine Besylate And Benazepril Hydrochloride	7	2.4	2.4
Loratadine Oral	37	2.4	2.4
Abiraterone Acetate	31	2.4	2.4
Ketoconazole	13	2.3	2.3
Mycophenolic Acid	24	2.3	2.3
Glyburide	18	2.3	2.3
Ruxolitinib	53	2.3	2.3
Valganciclovir Hydrochloride Powder,	9	2.3	2.3
Iron	49	2.3	2.3
Apixaban	49	2.3	2.3
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	15	2.3	2.3
Clarithromycin	25	2.3	2.3
Naproxen Sodium, Pseudoephedrine Hydrochloride	15	2.3	2.3
Tizanidine Hydrochloride	13	2.2	2.2
Montelukast	60	2.2	2.2
Metoprolol	180	2.2	2.2
Methocarbamol Tablets	12	2.2	2.2
Meclizine Hydrochloride	14	2.2	2.2
Atorvastatin Calcium, Film Coated	50	2.2	2.2
Metolazone	8	2.2	2.2
Lactulose	27	2.2	2.2
Metoprolol Tartrate	188	2.2	2.2
Metformin Hydrochloride	41	2.2	2.2
Citalopram	94	2.2	2.2
Gabapentin	246	2.1	2.1
Losartan	119	2.1	2.1
Itraconazole	8	2.1	2.1
Paliperidone Palmitate	22	2.1	2.1
Oxybutynin	20	2.1	2.1
Ketoconazole Foam	10	2.1	2.1
Terazosin Hydrochloride	6	2.1	2.1
Vismodegib	6	2.1	2.1
Ketoconazole Cream, 2%	10	2.1	2.1
Venlafaxine	48	2.1	2.1
Multivitamin	33	2.1	2.1
Tapentadol Hydrochloride	22	2.1	2.1
Thyroid, Porcine	7	2.0	2.0
Rosuvastatin	133	2.0	2.0
Pemetrexed	14	2.0	2.0
Ropinirole	10	2.0	2.0
Loperamide Hydrochloride	29	2.0	2.0
Metformin Hydrochloride Tablets	37	2.0	2.0
Metformin Hydrochloride Extended-Release Tablets	37	2.0	2.0
Metformin Hydrochloride Tablet	37	2.0	2.0
Fish Oil	58	2.0	2.0
Lanreotide Acetate	5	2.0	2.0
Duloxetine	44	2.0	2.0
Sumatriptan	24	2.0	2.0
Isosorbide Mononitrate	13	2.0	2.0
Warfarin Sodium	29	2.0	2.0
Amiodarone Hydrochloride	7	1.9	1.9
Letrozole Tablets	30	1.9	1.9
Methylphenidate	18	1.9	1.9
Anti-Thymocyte Globulin (Rabbit)	5	1.9	1.9
Brimonidine Tartrate	11	1.9	1.9
Chlorthalidone	7	1.9	1.9
Zidovudine	8	1.9	1.9
Everolimus Tablets	10	1.9	1.9
Carvedilol	80	1.9	1.9
Sirolimus	8	1.9	1.9
Methylphenidate Hydrochloride	35	1.8	1.8
Insulin Aspart	39	1.8	1.8
Atomoxetine Hydrochloride	14	1.8	1.8
Naltrexone Hydrochloride And Bupropion Hydrochloride	5	1.8	1.8
Interferon Beta-1B	11	1.8	1.8
Treprostinil	71	1.8	1.8
Pirfenidone	23	1.8	1.8
Norepinephrine	6	1.8	1.8
Latanoprost	28	1.7	1.7
Norepinephrine Bitartrate	8	1.7	1.7
Sumatriptan Succinate	14	1.7	1.7
Amlodipine Besylate And Valsartan	6	1.7	1.7
Etonogestrel And Ethinyl Estradiol	12	1.7	1.7
Sildenafil Citrate	66	1.6	1.6
Amantadine	8	1.6	1.6
Eszopiclone	13	1.6	1.6
Fluticasone Propionate And Salmeterol	21	1.6	1.6
Risperidone	66	1.6	1.6
Ranitidine	96	1.5	1.5
Budesonide, Glycopyrrolate, And Formoterol Fumarate	5	1.5	1.5
Bosentan	24	1.5	1.5
Insulin Degludec	11	1.5	1.5
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	14	1.4	1.4
Testosterone Cypionate	4	1.4	1.4
Abiraterone	6	1.4	1.4
Vilazodone Hydrochloride	4	1.4	1.4
Carbidopa And Levodopa	20	1.3	1.3
Golimumab	36	1.3	1.3
Dulaglutide	37	1.3	1.3
Rotigotine	6	1.3	1.3
Vedolizumab	35	1.3	1.3
Sofosbuvir	8	1.3	1.3
Pembrolizumab	42	1.2	1.2
Dronedarone	4	1.2	1.2
Mometasone Furoate And Formoterol Fumarate Dihydrate	6	1.2	1.2
Linaclotide	10	1.2	1.2
Fexofenadine Hydrochloride	8	1.1	1.1
Pemetrexed Disodium	14	1.1	1.1
Tenofovir Disoproxil Fumarate	12	1.1	1.1
Ambrisentan	45	1.1	1.1
Dornase Alfa	7	1.1	1.1
Emtricitabine And Tenofovir Disoproxil Fumarate	16	1.1	1.1
Tirzepatide	56	1.1	1.1
Buprenorphine	31	1.0	1.0
Temozolomide	7	1.0	1.0
Exenatide	17	1.0	1.0
Ustekinumab	32	1.0	1.0
Lifitegrast	5	1.0	1.0
Dimethyl Fumarate	35	0.9	0.9
Cabozantinib	13	0.8	0.8
Ranibizumab	7	0.8	0.8
Fremanezumab-Vfrm	3	0.8	0.8
Apalutamide	3	0.8	0.8
Ranitidine Hydrochloride	12	0.7	0.7
Sacubitril And Valsartan	25	0.7	0.7
Etonogestrel	10	0.7	0.7
Orlistat	5	0.6	0.6
Abaloparatide	5	0.5	0.5
Pimavanserin Tartrate	9	0.5	0.5
Guselkumab	5	0.4	0.4
Evolocumab	20	0.4	0.4
Apremilast	18	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.