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Which drugs are most reported with Extrasystoles?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,920 reports · 285 co-occurring drugs

As of the last recalculation, Extrasystoles appears in 6,920 FAERS reports alongside 285 co-occurring drug terms. The strongest observed disproportionality signal is SEVOFLURANE (PRR 17.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Sevoflurane	48	17.5	17.6
Dofetilide	46	13.3	13.3
Dronedarone	41	12.2	12.2
Captopril	25	7.8	7.9
Nebivolol	38	7.2	7.2
Alteplase	35	7.0	7.1
Digoxin	161	6.9	6.9
Theophylline	24	6.3	6.3
Theophylline Anhydrous	24	5.8	5.8
Salmeterol Xinafoate	16	5.6	5.6
Sotalol Hydrochloride	30	5.4	5.5
Nebivolol Hydrochloride	60	5.4	5.4
Felodipine Extended-Release Tablets	19	5.0	5.0
Felodipine	19	5.0	5.0
Amlodipine Besylate And Benazepril Hydrochloride	15	4.9	4.9
Enalapril Maleate	40	4.9	4.9
Bisoprolol Fumarate	210	4.8	4.8
Metoprolol Succinate	132	4.6	4.7
Gemfibrozil	23	4.6	4.6
Terazosin Hydrochloride	13	4.4	4.4
Diltiazem Hydrochloride	50	4.4	4.4
Tolterodine Tartrate	13	4.4	4.4
Atropine	12	4.4	4.4
Propofol	52	4.3	4.3
Nitroglycerin	76	4.3	4.3
Timolol Maleate	14	4.3	4.3
Valsartan And Hydrochlorothiazide	19	4.2	4.2
Ciclesonide	19	4.2	4.2
Atropine Sulfate	15	4.2	4.2
Metoprolol Succinate Er Tablets	84	4.1	4.1
Eplerenone	17	4.0	4.0
Irbesartan	59	4.0	4.0
Diltiazem Hydrochloride Extended-Release Tablets	15	4.0	4.0
Desloratadine	14	3.9	3.9
Olanzapine Pamoate	53	3.9	3.9
Fingolimod Hcl	110	3.9	3.9
Atenolol	168	3.9	3.9
Insulin Glulisine	13	3.9	3.9
Ipratropium Bromide	45	3.8	3.8
Cimetidine	12	3.8	3.8
Ciprofolxacin	84	3.6	3.6
Ciprofloxacin Tablets	84	3.6	3.6
Ciprofloxacin	103	3.4	3.4
Ticagrelor	36	3.4	3.4
Ciprofloxacin Hydrochloride	105	3.3	3.3
Midazolam Hydrochloride	29	3.2	3.3
Metoroprolol Tartrate	70	3.2	3.2
Potassium Chloride, Dextrose Monohydrate	98	3.2	3.2
Potassium Chloride Oral	98	3.2	3.2
Potassium Chloride Extended-Release	98	3.2	3.2
Fentanyl Citrate	19	3.2	3.2
Ezetimibe And Simvastatin	16	3.2	3.2
Vitamin E	33	3.2	3.2
Metoprolol Tartrate	279	3.2	3.2
Potassium Chloride	118	3.2	3.2
Norepinephrine Bitartrate	15	3.1	3.1
Magnesium	85	3.1	3.1
Midazolam	26	3.1	3.1
Amoxicillin And Clavulanate Potassium	28	3.1	3.1
Candesartan Cilexetil	27	3.1	3.1
Magnesium Sulfate In Water For	13	3.1	3.1
Siponimod	9	3.0	3.0
Magnesium Sulfate Heptahydrate	13	3.0	3.0
Magnesium Sulfate	13	3.0	3.0
Ascorbic Acid	23	3.0	3.0
Amiodarone Hydrochloride	11	3.0	3.0
Ramipril	120	2.9	2.9
Metoprolol	242	2.9	2.9
Simvastatin	238	2.9	2.9
Ozanimod Hydrochloride	8	2.9	2.9
Ciprofloxacin Hydrochloride And Hydrocortisone	20	2.9	2.9
Raloxifene Hydrochloride	14	2.9	2.9
Ranolazine	10	2.9	2.9
Enalapril	53	2.9	2.9
Hydrochlorothiazide	137	2.9	2.9
Levothyroxine Sodium	288	2.8	2.8
Thyroid, Porcine	10	2.8	2.8
Rocuronium Bromide	11	2.8	2.8
Trimethoprim	11	2.8	2.8
Quinine	8	2.8	2.8
Travoprost	8	2.8	2.8
Abacavir Sulfate	9	2.8	2.8
Metoprolol Tartrate Injection	172	2.8	2.8
Octreotide Acetate	28	2.8	2.8
Sacubitril And Valsartan	105	2.7	2.7
Rosuvastatin	182	2.7	2.7
Amlodipine Besylate And Valsartan	10	2.7	2.7
Doxazosin	25	2.7	2.7
Lanreotide Acetate	7	2.7	2.7
Valsartan	93	2.7	2.7
Azithromycin Dihydrate	52	2.7	2.7
Quinapril Hydrochloride	7	2.7	2.7
Warfarin Sodium	41	2.7	2.7
Aspirin 325 Mg	433	2.6	2.7
Aspirin 81 Mg	433	2.6	2.6
0Xygen	43	2.6	2.6
Oxygen	43	2.6	2.6
Levothyroxine Sodium Anhydrous	87	2.6	2.6
Carvedilol	117	2.6	2.6
Ezetimibe	65	2.6	2.6
Candesartan	31	2.6	2.6
Amlodipine Besylate	126	2.6	2.6
Aspirin	445	2.6	2.6
Dutasteride	7	2.6	2.6
Esomeprazole	53	2.6	2.6
Selexipag	22	2.6	2.6
Spironolactone	118	2.6	2.6
Lidocaine Hydrochloride And Epinephrine Bitartrate	45	2.5	2.5
Olanzapine	90	2.5	2.5
Lidicaine	41	2.5	2.5
Burn Relief	41	2.5	2.5
Lidocaine Hydrochloride And Epinephrine	41	2.5	2.5
Extended Phenytoin Sodium	14	2.5	2.5
Lithium	21	2.5	2.5
Lithium Bromatum	21	2.5	2.5
Teriparatide	93	2.5	2.5
Lidocaine, Menthol	41	2.5	2.5
Cholestyramine	10	2.5	2.5
Labetalol	11	2.5	2.5
Azithromycin Monohydrate	34	2.5	2.5
Lidocaine 4%	44	2.4	2.4
Propranolol Hydrochloride	58	2.4	2.4
Diphenhydramine Hcl	9	2.4	2.4
Doxazosin Mesylate	29	2.4	2.4
Metolazone	9	2.4	2.4
Azithromycin	32	2.4	2.4
Liraglutide	39	2.4	2.4
Mirtazapine	72	2.4	2.4
Losartan Potassium	62	2.4	2.4
Bicalutamide	12	2.4	2.4
Glyburide	19	2.4	2.4
Fremanezumab-Vfrm	9	2.4	2.4
Clonidine	40	2.4	2.4
Ropinirole	12	2.4	2.4
Furosemide	304	2.3	2.3
Niacin	9	2.3	2.3
Sucralfate Oral	11	2.3	2.3
Insulin	43	2.3	2.3
Sucralfate Oral Suspension	11	2.3	2.3
Rabeprazole Sodium	21	2.3	2.3
Bupivacaine	7	2.3	2.3
Sertraline	87	2.2	2.2
Venlafaxine Hydrochloride	98	2.2	2.2
Escitalopram Oxalate	54	2.2	2.2
Lidocaine	43	2.2	2.2
Methadone Hydrochloride	8	2.2	2.2
Fesoterodine Fumarate	8	2.2	2.2
Amlodipine	195	2.2	2.2
Citalopram Hydrobromide	78	2.2	2.2
Esomeprazole Magnesium	169	2.2	2.2
Bimatoprost	21	2.2	2.2
Niraparib	16	2.2	2.2
Human Insulin	9	2.2	2.2
Tizanidine Hydrochloride	13	2.2	2.2
Isosorbide Dinitrate	14	2.2	2.2
Atomoxetine Hydrochloride	17	2.2	2.2
Citalopram	97	2.1	2.1
Donepezil Hydrochloride	26	2.1	2.1
Clopidogrel	139	2.1	2.1
Icosapent Ethyl	6	2.1	2.1
Sertraline Hydrochloride	83	2.1	2.1
Lovastatin	18	2.1	2.1
Venlafaxine	50	2.1	2.1
Fish Oil	63	2.1	2.1
Brinzolamide	6	2.1	2.1
Alprazolam	140	2.1	2.1
Oxybutynin Chloride	6	2.1	2.1
Warfarin	86	2.0	2.1
Ondansetron	74	2.0	2.0
Ondansetron Tablets	74	2.0	2.0
Latanoprost	34	2.0	2.0
Ondansetron Hydrochloride	82	2.0	2.0
Loratadine Tablet	36	2.0	2.0
Budesonide, Glycopyrrolate, And Formoterol Fumarate	7	2.0	2.0
Indapamide	12	2.0	2.0
Lopinavir And Ritonavir	9	2.0	2.0
Allopurinol	103	2.0	2.0
Losartan	115	2.0	2.0
Norepinephrine	7	2.0	2.0
Heparin Sodium	9	2.0	2.0
Agalsidase Beta	6	2.0	2.0
Fexofenadine Hcl	6	2.0	2.0
Levofloxacin	39	2.0	2.0
Levofloxacin In 5% Dextrose	39	2.0	2.0
Clopidogrel Bisulfate	66	2.0	2.0
Abaloparatide	19	1.9	1.9
Nilotinib	19	1.9	1.9
Tenofovir Disoproxil Fumarate	21	1.9	1.9
Dorzolamide Hydrochloride And Timolol Maleate	5	1.9	1.9
Duloxetine Hydrochloride	116	1.9	1.9
Loperamide Hcl	8	1.9	1.9
Lisinopril	188	1.9	1.9
Conjugated Estrogens	36	1.9	1.9
Haloperidol	15	1.9	1.9
Metformin Er 500 Mg	183	1.9	1.9
Metformin Er 750 Mg	183	1.9	1.9
Atorvastatin Calcium	150	1.8	1.8
Estrogens, Conjugated	36	1.8	1.8
Haloperidol Lactate	15	1.8	1.8
Ribociclib	19	1.8	1.8
Febuxostat Tablets 40 Mg	6	1.8	1.8
Febuxostat Tablets 80 Mg	6	1.8	1.8
Lisinopril And Hydrochlorothiazide	6	1.8	1.8
Pitavastatin Calcium	6	1.8	1.8
Memantine	8	1.8	1.8
Memantine Hydrochloride	8	1.8	1.8
Levocetirizine Dihydrochloride	14	1.8	1.8
Timolol	7	1.7	1.7
Metformin Hcl	32	1.7	1.7
Pioglitazone	25	1.7	1.7
Dabrafenib	12	1.7	1.7
Trastuzumab	39	1.7	1.7
Loratadine	60	1.7	1.7
Ibrutinib	45	1.7	1.7
Tiotropium Bromide	76	1.7	1.7
Azelastine	10	1.7	1.7
Daptomycin	5	1.6	1.6
Rasagiline Mesylate	6	1.6	1.6
Trametinib	13	1.6	1.6
Efavirenz	6	1.6	1.6
Tiotropium Bromide Inhalation Spray	6	1.6	1.6
Epoprostenol	7	1.6	1.6
Tadalafil	53	1.6	1.6
Armodafinil	11	1.6	1.6
Ledipasvir And Sofosbuvir	10	1.6	1.6
Glimepiride	20	1.5	1.5
Oxybutynin	15	1.5	1.5
Droxidopa	11	1.5	1.5
Risperidone	67	1.5	1.5
Encorafenib	5	1.5	1.5
Loratadine And Pseudoephedrine Sulfate	4	1.5	1.5
Vemurafenib	6	1.5	1.5
Pertuzumab	13	1.4	1.4
Exenatide	25	1.4	1.4
Naltrexone Hydrochloride And Bupropion Hydrochloride	4	1.4	1.4
Velpatasvir And Sofosbuvir	6	1.4	1.4
Sofosbuvir	9	1.4	1.4
Dexlansoprazole	19	1.4	1.4
Brimonidine Tartrate	8	1.4	1.4
Sorafenib	9	1.3	1.3
Relugolix	10	1.3	1.3
Insulin Glargine	104	1.3	1.3
Cetuximab	13	1.2	1.2
Acetaminophen, Aspirin (Nsaid) And Caffeine	7	1.2	1.2
Oxaliplatin	30	1.2	1.2
Prasugrel Hydrochloride	4	1.2	1.2
Ofatumumab	13	1.2	1.2
Acetaminophen, Aspirin, And Caffeine	8	1.1	1.1
Vibegron	3	1.1	1.1
Interferon Beta-1B	7	1.1	1.1
Drospirenone And Ethinyl Estradiol	16	1.1	1.1
Umeclidinium Bromide And Vilanterol Trifenatate	6	1.1	1.1
Alirocumab	9	1.1	1.1
Bosentan	18	1.1	1.1
Ocrelizumab	22	1.1	1.1
Asenapine Maleate	3	1.0	1.0
Rucaparib	3	1.0	1.0
Tafamidis	4	1.0	1.0
Bosutinib	3	1.0	1.0
Avapritinib	4	1.0	1.0
Lapatinib	5	1.0	1.0
Botulinum Toxin Type A	4	1.0	1.0
Pirfenidone	13	1.0	1.0
Peginterferon Alfa-2A	17	0.9	0.9
Varenicline Tartrate	25	0.9	0.9
Teriflunomide	14	0.9	0.9
Abemaciclib	6	0.9	0.9
Remdesivir	4	0.9	0.9
Treprostinil	37	0.9	0.9
Abiraterone Acetate	12	0.9	0.9
Glatiramer Acetate	17	0.9	0.9
Levonorgestrel	57	0.9	0.9
Canagliflozin	8	0.8	0.8
Enzalutamide	14	0.7	0.7
Ambrisentan	29	0.7	0.7
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	4	0.7	0.7
Osimertinib	7	0.7	0.7
Lifitegrast	3	0.6	0.6
Erenumab-Aooe	10	0.5	0.5
Dulaglutide	16	0.5	0.5
Pimavanserin Tartrate	9	0.5	0.5
Evolocumab	26	0.5	0.5
Minoxidil	7	0.5	0.5
Galcanezumab-Gnlm	4	0.4	0.4
Copper	3	0.2	0.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.