Reaction

Endocarditis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,052 reports · 259 co-occurring drugs

As of the last recalculation, Endocarditis appears in 5,052 FAERS reports alongside 259 co-occurring drug terms. The strongest observed disproportionality signal is GENTAMICIN (PRR 34.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Gentamicin	106	34.1	34.4
Gentamicin Sulfate	120	32.0	32.3
Rifampicin	55	22.6	22.8
Daptomycin	49	22.1	22.2
Ampicillin	39	19.5	19.6
Ampicillin Sodium	39	19.5	19.6
Vancomycin	236	17.6	17.7
Vancomycin Hydrochloride	260	17.1	17.1
Cefazolin	28	12.7	12.7
Meropenem	96	12.5	12.6
Cefazolin Sodium	36	12.4	12.4
Ceftriaxone	90	11.5	11.5
Anti-Thymocyte Globulin (Rabbit)	22	11.3	11.3
Rifampin	39	11.1	11.1
Ceftriaxone Sodium	99	10.8	10.9
Remdesivir	31	9.6	9.7
Amphotericin B	28	9.3	9.3
Teduglutide	30	9.2	9.2
Valganciclovir Hydrochloride Powder,	27	9.2	9.2
Cefepime	31	9.0	9.0
Basiliximab	25	8.8	8.8
Linezolid	61	8.5	8.5
Cefepime Hydrochloride	33	8.5	8.5
Piperacillin Sodium And Tazobactam Sodium	38	8.0	8.0
Amphetamine	16	8.0	8.0
Posaconazole Delayed-Release	21	7.9	7.9
Epoetin Alfa	21	7.3	7.3
Mycophenolate Mofetil Hydrochloride	232	7.3	7.3
Micafungin Sodium	15	7.3	7.3
Mycophenolate Mofetil	231	7.3	7.3
Valganciclovir	33	7.3	7.3
Valganciclovir Hydrochloride	33	7.3	7.3
Fentanyl Citrate	29	6.7	6.7
Tacrolimus Ointment 0.1%	194	6.6	6.6
Tacrolimus Extended-Release Capsules	194	6.6	6.6
Prednisolone	274	6.6	6.6
Prednisolone Oral	274	6.6	6.6
Prednisolone Oral Solution	274	6.6	6.6
Tacrolimus	229	6.3	6.3
Metolazone	17	6.2	6.3
Mycophenilic Acid	31	6.2	6.2
Piperacillin And Tazobactam	19	6.1	6.1
Posaconazole	24	6.1	6.1
Voriconazole Injection	32	6.1	6.1
Mycophenolic Acid	47	6.1	6.1
Paricalcitol	19	5.6	5.6
Buprenorphine Hydrochloride, Naloxone Hydrochloride	32	5.5	5.5
Voriconazole	40	5.5	5.5
Chlorhexidine Gluconate	12	5.4	5.4
Epoprostenol	17	5.4	5.4
Agalsidase Beta	12	5.4	5.4
Methadone	55	5.3	5.3
Obinutuzumab	21	5.3	5.3
Erythropoietin	26	5.2	5.2
Azacitidine For	23	5.2	5.2
Ciprofolxacin	86	5.0	5.0
Ciprofloxacin Tablets	86	5.0	5.0
Piperacillin Sodium,Tazobactam Sodium	32	5.0	5.0
Busulfan	19	5.0	5.0
Everolimus Tablets	20	4.9	4.9
Sirolimus	16	4.9	4.9
Trimethoprim	14	4.9	4.9
Azacitidine	35	4.9	4.9
Amikacin	20	4.8	4.9
Baricitinib	11	4.7	4.7
Sevelamer Carbonate	13	4.7	4.7
Tretinoin	9	4.6	4.6
Warfarin	138	4.6	4.6
Methylprednisolone	147	4.5	4.5
Human Immunoglobulin G	22	4.4	4.4
Eculizumab	57	4.4	4.4
Norepinephrine Bitartrate	15	4.3	4.3
Cyclosporine	114	4.3	4.3
Cytarabine	62	4.3	4.3
Tocilizumab	116	4.3	4.3
Tolvaptan	15	4.3	4.3
Enalapril	57	4.3	4.3
Heparin Sodium	14	4.2	4.2
Daratumumab	40	4.2	4.2
Bisacodyl Suppositories	13	4.1	4.2
Umeclidinium	9	4.1	4.1
Biscodyl	13	4.1	4.1
Ciprofloxacin	90	4.1	4.1
Sodium Bicarbonate	23	4.1	4.1
Sodium Bicarbonate Injection,	23	4.1	4.1
Bumetanide	26	4.1	4.1
Insulin Glulisine	10	4.1	4.1
Warfarin Sodium	45	4.0	4.0
Melphalan	22	4.0	4.0
Blinatumomab	10	4.0	4.0
Ciprofloxacin Hydrochloride	91	3.9	3.9
Iron Sucrose	9	3.9	3.9
Itraconazole	11	3.9	3.9
Spironolactone	130	3.9	3.9
Norepinephrine	10	3.9	3.9
Enalapril Maleate	23	3.8	3.8
Cyclophosphamide Injection, Solution	160	3.8	3.8
Cyclophosphamide	160	3.8	3.8
Cyclophosphamide For Injection	160	3.8	3.8
Bisacodyl	13	3.8	3.8
Melphalan Hydrochloride	23	3.8	3.8
Anti-Itch	61	3.8	3.8
Anti-Pruritic	61	3.8	3.8
Antipruritic (Anti-Itch)	61	3.8	3.8
Cool Relief Gel With Aloe	61	3.8	3.8
Drs. Hydrocortisone	61	3.8	3.8
Hydrocortisone Continuous Spray	61	3.8	3.8
Hydrocortisone Spray	61	3.8	3.8
Anti-Itch Cream	61	3.8	3.8
Hydrocortisone Lotion	61	3.8	3.8
Hydrocortisone Cream 1%	61	3.8	3.8
Hydrocortisone Cream 1/2%	61	3.8	3.8
Hydrocortisone 1%	61	3.8	3.8
Hydrocortisone Cream	61	3.8	3.8
Bisoprolol Fumarate	121	3.7	3.7
Hydroxyurea	19	3.7	3.7
Digoxin	64	3.7	3.7
Telmisartan	16	3.7	3.7
Ganciclovir	9	3.6	3.6
Thalidomide	32	3.6	3.6
Furosemide	333	3.6	3.6
Clindamycin Phosphate	29	3.6	3.6
Fludarabine Phosphate	34	3.6	3.6
Insulin	48	3.6	3.6
Magnesium Sulfate In Water For	11	3.6	3.6
Hydrocortisone Acetate	62	3.5	3.5
Azathioprine	75	3.5	3.5
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	7	3.5	3.5
Ganciclovir Sodium	9	3.5	3.5
Tafamidis	10	3.5	3.5
Magnesium Sulfate Heptahydrate	11	3.5	3.5
Magnesium Sulfate	11	3.5	3.5
Metronidazole Topical	40	3.5	3.5
Docusate Sodium - Sennosides	27	3.5	3.5
Ketoprofen	11	3.5	3.5
Rituximab	173	3.5	3.5
Methadone Hydrochloride	9	3.4	3.4
Dexamethasone 1.5 Mg	232	3.4	3.4
Doxorubicin	72	3.4	3.4
Clindamycin	23	3.3	3.4
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	25	3.3	3.3
Dexamethasone	231	3.3	3.3
Amiodarone Hydrochloride	9	3.3	3.3
Human Insulin	10	3.3	3.3
Bosentan	40	3.3	3.3
Anastrozole Tablets	17	3.3	3.3
Enoxaparin Sodium	45	3.2	3.2
Hydrocodone Bitartrate And Acetaminophen	44	3.2	3.2
Amantadine	12	3.2	3.2
Leflunomide	80	3.2	3.2
Doxorubicin Hydrochloride	25	3.2	3.2
Levofloxacin	46	3.2	3.2
Levofloxacin In 5% Dextrose	46	3.2	3.2
Oseltamivir	6	3.1	3.1
Atovaquone	6	3.1	3.1
Cladribine	7	3.0	3.0
Fulvestrant	24	3.0	3.0
Hydromorphone Hydrochloride	66	3.0	3.0
Apixaban	48	3.0	3.0
Darbepoetin Alfa	38	2.9	2.9
Pravastatin Sodium	14	2.9	2.9
Clarithromycin	24	2.9	2.9
Pemetrexed	15	2.9	2.9
Mercaptopurine	12	2.9	2.9
Allopurinol	106	2.8	2.8
Isoniazid	11	2.8	2.8
Carboplatin	85	2.8	2.8
Nicotine Polacrilex Mini	10	2.7	2.8
Nicotine Polarilex	10	2.7	2.8
Sofosbuvir	13	2.7	2.7
Cisplatin	51	2.7	2.7
Ribavirin	42	2.7	2.7
Metoprolol Tartrate Injection	121	2.7	2.7
Paclitaxel (Aibumin-Bound)	52	2.6	2.6
Venetoclax	39	2.6	2.6
Ribociclib	20	2.6	2.6
Methoxy Polyethylene Glycol-Epoetin Beta	7	2.6	2.6
Amlodipine Besylate And Valsartan	7	2.6	2.6
Metoprolol Tartrate	168	2.6	2.6
Valacyclovir	26	2.6	2.6
Phenytoin	13	2.6	2.6
Bortezomib	55	2.6	2.6
Vincristine Sulfate	18	2.5	2.5
Metoprolol	153	2.5	2.5
Tramadol Hydrochloride	23	2.5	2.5
Treprostinil	76	2.5	2.5
Encorafenib	6	2.5	2.5
Linagliptin	11	2.5	2.5
Propofol	22	2.5	2.5
Iohexol	5	2.5	2.5
Peginterferon Alfa-2A	32	2.4	2.4
Atezolizumab	23	2.4	2.4
Isosorbide Mononitrate	12	2.4	2.4
Paclitaxel	57	2.4	2.4
Etoposide	42	2.4	2.4
Pegaspargase	7	2.4	2.4
Oxycodone Hydrochloride	122	2.3	2.3
Buprenorphine	51	2.3	2.3
Gefitinib	5	2.3	2.3
Fluorouracil Cream, 0.5%	42	2.3	2.3
Morphine Sulfate	66	2.3	2.3
Fluorouracil	42	2.2	2.2
Prochlorperazine Maleate	5	2.2	2.2
Selexipag	14	2.2	2.2
Pemetrexed Disodium	20	2.2	2.2
Pembrolizumab	55	2.2	2.2
Entecavir	6	2.1	2.1
Everolimus	26	2.1	2.1
Cetuximab	16	2.1	2.1
Riociguat	16	2.0	2.0
Dasatinib	18	2.0	2.0
Sildenafil Citrate	61	2.0	2.0
Pertuzumab	13	2.0	2.0
Granisetron	5	2.0	2.0
Ambrisentan	58	1.9	1.9
Alteplase	7	1.9	1.9
Macitentan	32	1.9	1.9
Tadalafil	46	1.9	1.9
Palivizumab	7	1.9	1.9
Testosterone Cypionate	4	1.8	1.8
Dolutegravir Sodium	4	1.8	1.8
Dabigatran Etexilate	34	1.8	1.8
Rifaximin	9	1.8	1.8
Bevacizumab	53	1.8	1.8
Oxycodone And Acetaminophen	10	1.8	1.8
Trastuzumab	29	1.7	1.7
Ledipasvir And Sofosbuvir	8	1.7	1.7
Deferasirox	11	1.7	1.7
Dabigatran Etexilate Mesylate	30	1.7	1.7
Dapagliflozin	13	1.7	1.7
Axicabtagene Ciloleucel	4	1.7	1.7
Nivolumab	39	1.7	1.7
Romiplostim	6	1.6	1.6
Ipilimumab	17	1.6	1.6
Rivaroxaban	81	1.6	1.6
Dofetilide	4	1.6	1.6
Ravulizumab	5	1.5	1.5
Medroxyprogesterone Acetate	18	1.5	1.5
Clozapine	44	1.4	1.4
Belimumab	11	1.4	1.4
Voclosporin	3	1.4	1.4
Bendamustine Hydrochloride	4	1.4	1.4
Trametinib	8	1.4	1.4
Fam-Trastuzumab Deruxtecan-Nxki	3	1.2	1.2
Abiraterone	4	1.2	1.2
Naltrexone	9	1.2	1.2
Sacubitril And Valsartan	33	1.2	1.2
Glecaprevir And Pibrentasvir	3	1.1	1.1
Abiraterone Acetate	11	1.1	1.1
Apalutamide	3	1.1	1.1
Osimertinib	8	1.0	1.0
Ixazomib	7	1.0	1.0
Emicizumab	3	1.0	1.0
Lenalidomide	91	0.9	0.9
Cinacalcet Hydrochloride	9	0.8	0.8
Sarilumab	5	0.8	0.8
Minoxidil Foam 5% (Womens)	6	0.7	0.7
Pomalidomide	15	0.6	0.6
Minoxidil	6	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.