Reaction

Compression Fracture reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,138 reports · 311 co-occurring drugs

As of the last recalculation, Compression Fracture appears in 5,138 FAERS reports alongside 311 co-occurring drug terms. The strongest observed disproportionality signal is ROMOSOZUMAB-AQQG (PRR 55.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Romosozumab-Aqqg	179	55.3	56.0
Raloxifene Hydrochloride	74	20.8	20.9
Teriparatide	450	17.6	17.7
Chlorhexidine Gluconate	34	15.2	15.2
Alendronate Sodium	353	15.1	15.2
Denosumab	525	11.6	11.6
Zoledronic Acid	106	10.9	10.9
Abaloparatide	63	8.8	8.8
Risedronate Sodium	66	8.7	8.7
Docusate Sodium - Sennosides	65	8.3	8.3
Thalidomide	72	8.0	8.1
Emtricitabine And Tenofovir Alafenamide	22	7.9	7.9
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	19	7.7	7.7
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	16	7.2	7.2
Dimenhydrinate	18	6.9	6.9
Magnesium Oxide	69	6.8	6.8
Goserelin	22	6.7	6.7
Amlodipine Besylate And Benazepril Hydrochloride	15	6.6	6.6
Docusate Sodium	90	6.4	6.4
Bortezomib	138	6.4	6.4
Promethazine Hydrochloride	29	6.4	6.4
Cimetidine	15	6.3	6.3
Diphenoxylate Hydrochloride And Atropine Sulfate	21	6.2	6.2
Meperidine Hydrochloride	14	6.2	6.2
Calcium Gluconate	18	6.1	6.1
Calcium	212	6.0	6.0
Cyclobenzaprine Hydrochloride	13	5.9	5.9
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	26	5.8	5.8
Standardized Senna Concentrate	18	5.8	5.8
Prochlorperazine Maleate	13	5.7	5.7
Bicalutamide	21	5.6	5.6
0Xygen	67	5.6	5.6
Oxygen	67	5.6	5.6
Rabeprazole Sodium	37	5.5	5.5
Exemestane	28	5.3	5.3
Antacid	61	5.3	5.3
Emtricitabine And Tenofovir Disoproxil Fumarate	58	5.2	5.2
Sennosides	38	5.2	5.2
Magnesium Hydroxide	17	5.1	5.1
Morphine	92	5.1	5.1
Methylprednisolone Acetate	10	5.1	5.1
Sennosides 8.6 Mg Tablets	26	5.0	5.1
Senna	26	5.0	5.0
Dalteparin Sodium	13	5.0	5.0
Human Immunoglobulin G	25	4.9	4.9
Anastrozole	44	4.9	4.9
Melphalan Hydrochloride	30	4.9	4.9
Prochlorperazine	33	4.8	4.9
Melphalan	27	4.8	4.8
Calcium Carbonate	79	4.8	4.8
Teduglutide	16	4.8	4.8
Dexamethasone Sodium Phosphate	12	4.8	4.8
Vitamin E	37	4.8	4.8
Rabeprazole	26	4.8	4.8
Pitavastatin Calcium	12	4.8	4.8
Diphenhydramine Hydrochloride Capsule, Liquid Filled	25	4.8	4.8
Lubiprostone	11	4.7	4.7
Magnesium	92	4.6	4.6
Senna Leaf	26	4.6	4.6
Fulvestrant	37	4.6	4.6
Vibegron	9	4.6	4.6
Cyclobenzaprine	55	4.5	4.5
Ciprofloxacin Hydrochloride And Hydrocortisone	23	4.5	4.5
Lapatinib	17	4.5	4.5
Bisacodyl Suppositories	14	4.4	4.4
Alendronate Sodium Tablet	20	4.4	4.4
Ascorbic Acid	25	4.4	4.4
Biscodyl	14	4.4	4.4
Ado-Trastuzumab Emtansine	9	4.3	4.3
Fentanyl Citrate	19	4.3	4.3
Clindamycin	30	4.3	4.3
Nystatin Ointment	27	4.2	4.2
Letrozole	63	4.2	4.2
Nystatin Cream	27	4.2	4.2
Ergocalciferol	375	4.2	4.2
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	21	4.1	4.2
Naproxen Sodium, Pseudoephedrine Hydrochloride	21	4.1	4.1
Methocarbamol	23	4.1	4.1
Docusate Sodium 100Mg	24	4.1	4.1
Tenofovir Disoproxil Fumarate	33	4.1	4.1
Lactulose	38	4.0	4.0
Bisacodyl	14	4.0	4.0
Gentamicin	13	4.0	4.0
Metronidazole	63	4.0	4.0
Clindamycin Phosphate	33	4.0	4.0
Nystatin	27	4.0	4.0
Diltiazem Hydrochloride	34	4.0	4.0
Potassium Chloride	110	4.0	4.0
Clotrimazole	12	4.0	4.0
Erythropoietin	20	4.0	4.0
Fexofenadine Hcl	9	3.9	4.0
Celecoxib	124	3.9	3.9
Carfilzomib	27	3.9	3.9
Drs. Clotrimazole	11	3.9	3.9
Family Wellness Clotrimazole	11	3.9	3.9
Clotrimazole Topical	11	3.9	3.9
Gentamicin Sulfate	15	3.9	3.9
Losartan Potassium And Hydrochlorothiazide	11	3.8	3.8
Dexamethasone 1.5 Mg	267	3.8	3.8
Potassium Chloride, Dextrose Monohydrate	86	3.8	3.8
Potassium Chloride Oral	86	3.8	3.8
Potassium Chloride Extended-Release	86	3.8	3.8
Dexamethasone	267	3.8	3.8
Quinine	8	3.8	3.8
Ursosiol	18	3.8	3.8
Cephalexin	20	3.8	3.8
Polyethylene Glycol	10	3.7	3.8
Oxycodone Hydrochloride And Acetaminophen	90	3.7	3.7
Meclizine	15	3.7	3.7
Eszopiclone	23	3.7	3.7
Asfotase Alfa	9	3.6	3.6
Lenalidomide	359	3.6	3.6
Enoxaparin Sodium	51	3.6	3.6
Metolazone	10	3.6	3.6
Theophylline Anhydrous	11	3.6	3.6
Temazepam	33	3.6	3.6
Acyclovir	99	3.6	3.6
Clobetasol Propionate Ointment Usp, 0.05%	9	3.5	3.5
Ursodiol	19	3.5	3.5
Ixazomib	25	3.5	3.5
Dronabinol	7	3.5	3.5
Clobetasol Propionate	9	3.5	3.5
Theophylline	10	3.5	3.5
Meclizine Hydrochloride	17	3.5	3.5
Budesonide, Glycopyrrolate, And Formoterol Fumarate	9	3.5	3.5
Prednisolone	150	3.4	3.4
Prednisolone Oral	150	3.4	3.4
Prednisolone Oral Solution	150	3.4	3.4
Magnesium Sulfate Heptahydrate	11	3.4	3.4
Epoetin Alfa	10	3.4	3.4
Anastrozole Tablets	18	3.4	3.4
Oxycodone And Acetaminophen Tablets	10	3.4	3.4
Methocarbamol Tablets	14	3.4	3.4
Cefazolin Sodium	10	3.4	3.4
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	25	3.4	3.4
Zolpidem Tartrate	110	3.3	3.3
Lidicaine	40	3.3	3.3
Burn Relief	40	3.3	3.3
Lidocaine Hydrochloride And Epinephrine	40	3.3	3.3
Ketoconazole Foam	12	3.3	3.3
Lidocaine, Menthol	40	3.3	3.3
Psyllium Husk	8	3.3	3.3
Lidocaine Hydrochloride And Epinephrine Bitartrate	43	3.3	3.3
Ketoconazole Cream, 2%	12	3.3	3.3
Meclizine Hcl 12.5Mg	11	3.3	3.3
Meclizine Hcl 25Mg	11	3.3	3.3
Meclizine Hcl 12.5 Mg	11	3.3	3.3
Meclizine Hcl 25 Mg	11	3.3	3.3
Tiotropium Bromide Inhalation Spray	9	3.3	3.3
Polyethylene Glycol 3350	76	3.3	3.3
Sulfamethoxazole And Trimethoprim	67	3.2	3.2
Oxybutynin Chloride	7	3.2	3.2
Pemetrexed	17	3.2	3.2
Fentanyl	77	3.2	3.2
Diclofenac Sodium 1%	28	3.2	3.2
Diclofenac Sodium Topical	28	3.2	3.2
Primidone	8	3.2	3.2
Diclofenac Sodium Topical Gel, 1%	28	3.2	3.2
Magnesium Sulfate In Water For	10	3.2	3.2
Tolterodine Tartrate	7	3.2	3.2
Lidocaine	45	3.1	3.1
Famotidine	90	3.1	3.1
Doxorubicin Hydrochloride	25	3.1	3.1
Magnesium Sulfate	10	3.1	3.1
Methimazole	6	3.1	3.1
Lidocaine 4%	41	3.1	3.1
Guaifenesin	23	3.1	3.1
Cholestyramine	9	3.0	3.0
Metoclopramide Hydrochloride	57	3.0	3.0
Ravulizumab	10	3.0	3.0
Donepezil Hydrochloride	27	3.0	3.0
Vitamin C	67	3.0	3.0
Carisoprodol	14	3.0	3.0
Oxycodone	134	3.0	3.0
Bumetanide	19	2.9	2.9
Timolol Maleate	7	2.9	2.9
Furosemide	272	2.8	2.8
Dicyclomine Hydrochloride	10	2.8	2.8
Ferrous Sulfate	35	2.8	2.8
Selexipag	18	2.8	2.8
Calcium, Magnesium, Potassium, And Sodium Oxybates	6	2.8	2.8
Pomalidomide	71	2.8	2.8
Ketoconazole	12	2.8	2.8
Warfarin Sodium	32	2.8	2.8
Tolvaptan	10	2.8	2.8
Febuxostat Tablets 40 Mg	7	2.8	2.8
Febuxostat Tablets 80 Mg	7	2.8	2.8
Ibuprofen And Diphenhydramine Citrate	16	2.8	2.8
Oxycodone And Acetaminophen	16	2.8	2.8
Entecavir	8	2.8	2.8
Testosterone	16	2.8	2.8
Filgrastim	25	2.7	2.7
Oxycodone Hydrochloride	142	2.7	2.7
Multivitamin	33	2.7	2.7
Memantine	9	2.7	2.7
Memantine Hydrochloride	9	2.7	2.7
Esomeprazole Magnesium	151	2.7	2.7
Hydromorphone Hydrochloride	60	2.7	2.7
Letrozole Tablets	31	2.6	2.6
Warfarin	81	2.6	2.6
Metoroprolol Tartrate	42	2.6	2.6
Panitumumab	10	2.6	2.6
Levofloxacin	38	2.6	2.6
Levofloxacin In 5% Dextrose	38	2.6	2.6
Pemetrexed Disodium	24	2.6	2.6
Capecitabine	57	2.5	2.5
Pertuzumab	17	2.5	2.5
Estrogens, Conjugated	37	2.5	2.5
Vancomycin Hydrochloride	41	2.5	2.5
Conjugated Estrogens	36	2.5	2.5
Fondaparinux Sodium	5	2.5	2.5
Suvorexant	8	2.5	2.5
Ritonavir	18	2.5	2.5
Polatuzumab Vedotin	6	2.5	2.5
Metoprolol Succinate	53	2.5	2.5
Eltrombopag Olamine	14	2.5	2.5
Voriconazole Injection	13	2.4	2.4
Tocilizumab	67	2.4	2.4
Lopinavir And Ritonavir	8	2.4	2.4
Vancomycin	34	2.4	2.4
Insulin Glulisine	6	2.4	2.4
Dronedarone	6	2.4	2.4
Loperamide Hydrochloride Oral	6	2.4	2.4
Lovastatin	15	2.4	2.4
Selinexor	5	2.3	2.3
Fluticasone Propionate And Salmeterol	24	2.3	2.3
Instalax Polyethylene Glycol 3350	7	2.3	2.3
Human Insulin	7	2.3	2.3
Erlotinib Hydrochloride	7	2.3	2.3
Leuprolide Acetate	43	2.3	2.3
Rotigotine	8	2.2	2.2
Fexofenadine Hydrochloride	12	2.2	2.2
Polyethylene Glycol 400	7	2.2	2.2
Daratumumab	22	2.2	2.2
Macitentan	38	2.2	2.2
Linagliptin	10	2.2	2.2
Sildenafil Citrate	69	2.2	2.2
Irinotecan Hydrochloride	7	2.2	2.2
Rasagiline Mesylate	6	2.2	2.2
Methadone	23	2.2	2.2
Osimertinib	17	2.2	2.2
Enzalutamide	31	2.1	2.1
Trastuzumab	36	2.1	2.1
Rifaximin	11	2.1	2.1
Desvenlafaxine Succinate	14	2.1	2.1
Baricitinib	5	2.1	2.1
Conjugated Estrogens And Medroxyprogesterone Acetate	12	2.1	2.1
Loratadine And Pseudoephedrine Sulfate	4	2.0	2.0
Levocetirizine Dihydrochloride	12	2.0	2.0
Tobramycin Solution	6	2.0	2.0
Morphine Sulfate	60	2.0	2.0
Acalabrutinib	6	2.0	2.0
Upadacitinib	40	2.0	2.0
Durvalumab	10	2.0	2.0
Riociguat	16	2.0	2.0
Pioglitazone	21	2.0	2.0
Darbepoetin Alfa	26	2.0	2.0
Brexpiprazole	8	2.0	2.0
Blinatumomab	5	1.9	1.9
Insulin Degludec	11	1.9	1.9
Fesoterodine Fumarate	5	1.9	1.9
Ibrutinib	37	1.9	1.9
Bosentan	23	1.9	1.9
Bendamustine Hcl	7	1.8	1.8
Benralizumab	9	1.8	1.8
Treprostinil	56	1.8	1.8
Umeclidinium	4	1.8	1.8
Abiraterone	6	1.8	1.8
Doxorubicin	37	1.7	1.7
Mirabegron	16	1.7	1.7
Levodopa	5	1.7	1.7
Dabigatran Etexilate	32	1.7	1.7
Erlotinib	4	1.7	1.7
Linaclotide	11	1.7	1.7
Oseltamivir Phosphate	10	1.7	1.7
Emicizumab	5	1.6	1.6
Alteplase	6	1.6	1.6
Romiplostim	6	1.6	1.6
Lenvatinib	13	1.6	1.6
Dabigatran Etexilate Mesylate	28	1.6	1.6
Mometasone Furoate And Formoterol Fumarate Dihydrate	6	1.6	1.6
Nintedanib	12	1.6	1.6
Oseltamivir	3	1.5	1.5
Hydrocodone Bitartrate And Acetaminophen	21	1.5	1.5
Iohexol	3	1.5	1.5
Palbociclib	34	1.4	1.4
Docetaxel Anhydrous	24	1.4	1.4
Docetaxel	24	1.4	1.4
Abatacept	48	1.4	1.4
Hydrocodone Bitartrate	15	1.4	1.4
Sarilumab	9	1.4	1.4
Apalutamide	4	1.4	1.4
Tafamidis	4	1.4	1.4
Siponimod	3	1.4	1.4
Avapritinib	4	1.3	1.3
Abiraterone Acetate	13	1.3	1.3
Ambrisentan	39	1.3	1.3
Nivolumab	30	1.3	1.3
Risankizumab-Rzaa	25	1.2	1.2
Abemaciclib	6	1.2	1.2
Fam-Trastuzumab Deruxtecan-Nxki	3	1.2	1.2
Pirfenidone	12	1.2	1.2
Olaparib	6	1.2	1.2
Medroxyprogesterone Acetate	13	1.1	1.1
Ledipasvir And Sofosbuvir	5	1.1	1.1
Cabozantinib	12	1.0	1.0
Dalfampridine	17	1.0	1.0
Relugolix	5	0.9	0.9
Pimavanserin Tartrate	10	0.7	0.7
Galcanezumab-Gnlm	4	0.5	0.5
Cinacalcet Hydrochloride	5	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.