Reaction

Diabetic Neuropathy reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,914 reports · 309 co-occurring drugs

As of the last recalculation, Diabetic Neuropathy appears in 4,914 FAERS reports alongside 309 co-occurring drug terms. The strongest observed disproportionality signal is ZIPRASIDONE MESYLATE (PRR 49.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ziprasidone Mesylate	162	49.7	50.3
Ziprasidone	165	41.0	41.4
Olanzapine Pamoate	367	41.0	41.3
Insulin Human	251	28.1	28.3
Human Insulin	74	25.5	25.6
Quetiapine	850	22.4	22.5
Gemfibrozil	69	19.5	19.6
Glyburide	102	18.2	18.3
Insulin Glargine-Yfgn	91	17.9	18.0
Insulin Degludec	97	17.8	17.9
Pioglitazone	175	17.7	17.8
Insulin Aspart	261	17.6	17.7
Divalproex Sodium	182	17.2	17.2
Glipizide	235	17.1	17.2
Insulin	206	16.3	16.3
Olanzapine	379	16.1	16.2
Insulin Lispro	463	15.6	15.6
Lithium Carbonate	61	15.4	15.4
Amlodipine Besylate And Benazepril Hydrochloride	31	14.3	14.3
Ezetimibe And Simvastatin	48	13.5	13.5
Sitagliptin And Metformin Hydrochloride	66	13.1	13.2
Insulin Glulisine	31	13.0	13.0
Insulin Glargine	639	12.5	12.5
Risperidone	346	11.8	11.8
Enalapril Maleate	68	11.8	11.8
Glimepiride	100	11.1	11.1
Temazepam	95	10.9	10.9
Metformin Hcl	138	10.8	10.9
Sitagliptin	174	10.6	10.6
Meclizine Hcl 12.5Mg	33	10.3	10.3
Meclizine Hcl 25Mg	33	10.3	10.3
Meclizine Hcl 12.5 Mg	33	10.3	10.3
Meclizine Hcl 25 Mg	33	10.3	10.3
Captopril	23	10.2	10.2
Nitroglycerin	123	9.9	10.0
Pregabalin	558	9.7	9.7
Atorvastatin Calcium	509	9.6	9.6
Lisinopril And Hydrochlorothiazide	23	9.6	9.6
Trazodone Hydrochloride	35	9.5	9.6
Lovastatin	57	9.5	9.5
Tolterodine Tartrate	20	9.5	9.5
Gabapentin	705	9.4	9.4
Bupropion Hydrochloride	208	9.3	9.3
Lisinopril And Hydrochlorothiazide Tablets	17	9.2	9.2
Promethazine Hydrochloride	40	9.2	9.2
Meclizine	35	9.1	9.2
Metformin	670	9.0	9.1
Metformin Er 500 Mg	575	9.0	9.1
Metformin Er 750 Mg	575	9.0	9.1
Methocarbamol	48	9.0	9.1
Buspirone Hydrochloride	23	8.9	8.9
Paroxetine Hydrochloride	177	8.5	8.5
Carisoprodol	38	8.5	8.5
Metolazone	22	8.3	8.3
Meclizine Hydrochloride	38	8.3	8.3
Valsartan And Hydrochlorothiazide	26	8.1	8.2
Tizanidine Hydrochloride	34	8.0	8.0
Venlafaxine Hydrochloride	233	7.8	7.8
Losartan Potassium And Hydrochlorothiazide	21	7.7	7.7
Sertraline Hydrochloride	206	7.6	7.7
Oxcarbazepine	58	7.6	7.6
Clonazepam	273	7.6	7.6
Atenolol	228	7.6	7.6
Carbamazepine	116	7.5	7.5
Metformin Hydrochloride Tablets	98	7.4	7.4
Metformin Hydrochloride Extended-Release Tablets	98	7.4	7.4
Metformin Hydrochloride Tablet	98	7.4	7.4
Metformin Hydrochloride	101	7.4	7.4
Zolpidem Tartrate	225	7.3	7.4
Aripiprazole	203	7.3	7.3
Lisinopril	478	7.2	7.2
Methocarbamol Tablets	27	6.9	6.9
Primidone	16	6.7	6.7
Simvastatin	362	6.5	6.5
Fluoxetine Hydrochloride	189	6.5	6.5
Diltiazem Hydrochloride	52	6.4	6.4
Rabeprazole Sodium	41	6.4	6.4
Sucralfate	36	6.4	6.4
Mirtazapine	134	6.3	6.4
Liraglutide	73	6.3	6.3
Metoclopramide Hydrochloride	113	6.3	6.3
Linagliptin	27	6.3	6.3
Cephalexin	32	6.3	6.3
Lorazepam	254	6.3	6.3
Escitalopram	200	6.3	6.3
Ibuprofen And Diphenhydramine Citrate	34	6.2	6.2
Nystatin Ointment	38	6.2	6.2
Nystatin Cream	38	6.2	6.2
Isosorbide Dinitrate	28	6.1	6.1
Hydrochlorothiazide	202	6.1	6.1
Lithium	36	6.1	6.1
Lithium Bromatum	36	6.1	6.1
Citalopram	190	6.1	6.1
Eplerenone	18	6.0	6.0
Exenatide	73	5.9	6.0
Enalapril	77	5.9	5.9
Nystatin	38	5.9	5.9
Quinapril Hydrochloride	11	5.9	5.9
Clonidine	69	5.8	5.8
Amlodipine Besylate And Valsartan	15	5.8	5.8
Cimetidine	13	5.7	5.7
Docusate Sodium - Sennosides	43	5.7	5.7
Dicyclomine Hydrochloride	19	5.7	5.7
Loratadine Oral	65	5.7	5.7
Alendronate Sodium	130	5.6	5.6
Fenofibrate	46	5.5	5.5
Meperidine Hydrochloride	12	5.5	5.5
Ciprofloxacin Hydrochloride And Hydrocortisone	27	5.5	5.5
Duloxetine Hydrochloride	235	5.5	5.5
Pantoprazole Sodium	187	5.5	5.5
Irbesartan	56	5.4	5.4
Liothyronine Sodium	11	5.4	5.4
Docusate Sodium	72	5.3	5.4
Extended Phenytoin Sodium	21	5.3	5.3
Rosuvastatin	241	5.2	5.2
Topiramate	112	5.2	5.2
Docusate Sodium 100Mg	29	5.2	5.2
Furosemide	451	5.1	5.2
Carvedilol	160	5.1	5.2
Niacin	14	5.1	5.1
Alprazolam	239	5.1	5.1
Albuterol	141	5.1	5.1
Amlodipine Besylate	171	5.1	5.1
Nifedipine	56	5.1	5.1
Valsartan	123	5.1	5.1
Eszopiclone	30	5.0	5.0
Empagliflozin	77	4.9	4.9
Ezetimibe	85	4.9	4.9
Colchicine	30	4.8	4.9
Canagliflozin	34	4.8	4.8
Theophylline	13	4.8	4.8
Rabeprazole	25	4.8	4.8
Losartan Potassium	88	4.8	4.8
Aspirin 325 Mg	529	4.8	4.8
Aspirin 81 Mg	529	4.8	4.8
Sucralfate Oral	16	4.8	4.8
Sucralfate Oral Suspension	16	4.8	4.8
Aspirin	549	4.7	4.7
Cyclobenzaprine Hydrochloride	10	4.7	4.7
Doxepin Hydrochloride	14	4.7	4.7
Amitriptyline Hydrochloride	19	4.6	4.6
Ketoconazole Foam	16	4.6	4.6
Ketoconazole Cream, 2%	16	4.6	4.6
Amiodarone Hydrochloride	12	4.5	4.5
Clopidogrel	204	4.5	4.5
Lubiprostone	10	4.5	4.5
Potassium Chloride	118	4.5	4.5
Cyclobenzaprine	52	4.5	4.5
Quinine	9	4.5	4.5
Theophylline Anhydrous	13	4.5	4.5
Ketoconazole	18	4.4	4.4
Diazepam	124	4.4	4.4
Terazosin Hydrochloride	9	4.3	4.3
Loratadine	107	4.3	4.3
Metoprolol Succinate	86	4.3	4.3
Torsemide	33	4.2	4.2
Naproxen	77	4.2	4.2
Bumetanide	26	4.2	4.2
Guaifenesin	30	4.2	4.2
Indomethacin	13	4.2	4.2
Hyoscyamine Sulfate	9	4.2	4.2
Metoroprolol Tartrate	64	4.2	4.2
Levothyroxine Sodium	293	4.1	4.1
Digoxin	69	4.1	4.1
Conjugated Estrogens	56	4.1	4.1
Mupirocin	13	4.1	4.1
Potassium Chloride, Dextrose Monohydrate	88	4.1	4.1
Potassium Chloride Oral	88	4.1	4.1
Potassium Chloride Extended-Release	88	4.1	4.1
Raloxifene Hydrochloride	14	4.1	4.1
Vitamin E	30	4.1	4.1
Oxycodone Hydrochloride And Acetaminophen	93	4.0	4.0
Drs. Clotrimazole	11	4.0	4.0
Family Wellness Clotrimazole	11	4.0	4.0
Clotrimazole Topical	11	4.0	4.0
Estrogens, Conjugated	56	4.0	4.0
Zonisamide	14	4.0	4.0
Mupirocin Calcium	13	4.0	4.0
Lansoprazole	163	4.0	4.0
Montelukast Sodium	111	3.9	3.9
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	19	3.9	3.9
Naproxen Sodium, Pseudoephedrine Hydrochloride	19	3.9	3.9
Esomeprazole Magnesium	209	3.9	3.9
Benzonatate	15	3.9	3.9
Metoprolol Succinate Er Tablets	56	3.8	3.8
Ipratropium Bromide	32	3.8	3.8
Diphenhydramine Hcl	10	3.8	3.8
Clotrimazole	11	3.8	3.8
Metoprolol Tartrate	236	3.8	3.8
Spironolactone	123	3.8	3.8
Levothyroxine Sodium Anhydrous	87	3.7	3.7
Losartan	149	3.7	3.7
Dulaglutide	76	3.7	3.7
Doxazosin Mesylate	31	3.7	3.7
Chlorthalidone	10	3.7	3.7
Erythromycin	16	3.6	3.6
Bisacodyl	12	3.6	3.6
Bisacodyl Suppositories	11	3.6	3.6
Celecoxib	110	3.6	3.6
Ropinirole	13	3.6	3.6
Biscodyl	11	3.6	3.6
Metoclopramide	46	3.6	3.6
Omeprazole Magnesium	356	3.6	3.6
Olmesartan Medoxomil	30	3.6	3.6
Propranolol Hydrochloride	59	3.5	3.5
Mometasone Furoate	34	3.5	3.5
Sumatriptan	31	3.5	3.5
Fish Oil	73	3.5	3.5
Zinc	20	3.4	3.4
Amoxicillin And Clavulanate Potassium	22	3.4	3.4
Psyllium Husk	8	3.4	3.4
Modafinil	26	3.4	3.4
Zinc Chloride	20	3.4	3.4
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	40	3.4	3.4
Hydroxyzine	38	3.4	3.4
Dapagliflozin	25	3.4	3.4
Diltiazem Hydrochloride Extended-Release Tablets	9	3.4	3.4
Fluconazole	55	3.4	3.4
Doxepin	8	3.3	3.3
Nitrofurantoin	13	3.3	3.3
Loratadine Tablet	42	3.3	3.3
Tamsulosin Hydrochloride	16	3.3	3.3
Nitrofurantoin (Monohydrate/Macrocrystals)	13	3.3	3.3
Isosorbide Mononitrate	16	3.3	3.3
Oral Semaglutide	56	3.3	3.3
Zinc Gluconate	20	3.2	3.3
Atorvastatin Calcium, Film Coated	53	3.2	3.2
Epoetin Alfa	9	3.2	3.2
Oxycodone And Acetaminophen Tablets	9	3.2	3.2
Desloratadine	8	3.2	3.2
Meloxicam	43	3.2	3.2
Oxycodone And Acetaminophen	17	3.1	3.1
Instalax Polyethylene Glycol 3350	9	3.1	3.1
Famotidine	84	3.1	3.1
Melatonin	39	3.1	3.1
Polyethylene Glycol 400	9	3.0	3.0
Metoprolol	175	3.0	3.0
Felodipine Extended-Release Tablets	8	3.0	3.0
Felodipine	8	3.0	3.0
Fluoxetine	46	2.9	2.9
Duloxetine	48	2.9	2.9
Diazepam Oral Solution (Concentrate)	61	2.9	2.9
Diazepam Oral	61	2.9	2.9
Baclofen	59	2.9	2.9
Prasugrel Hydrochloride	7	2.9	2.9
Albuterol Sulfate	199	2.9	2.9
Methadone	29	2.9	2.9
Diclofenac Sodium 1%	24	2.9	2.9
Diclofenac Sodium Topical	24	2.9	2.9
Diclofenac Sodium Topical Gel, 1%	24	2.8	2.9
Fluticasone Propionate And Salmeterol Xinafoate	40	2.8	2.8
Finasteride	40	2.8	2.8
Haloperidol	16	2.8	2.8
Naproxen Sodium	92	2.8	2.8
Calcitriol Capsules 0.25 Mcg	13	2.8	2.8
Calcitriol Capsules 0.5 Mcg	13	2.8	2.8
Fexofenadine Hcl	6	2.8	2.8
Allopurinol	100	2.7	2.7
Haloperidol Lactate	16	2.7	2.7
Methadone Hydrochloride	7	2.7	2.7
Calcitriol	13	2.7	2.7
Hydrocodone Bitartrate And Acetaminophen	36	2.7	2.7
Warfarin Sodium	29	2.7	2.7
Lamotrigine	81	2.6	2.6
Selexipag	16	2.6	2.6
Fondaparinux Sodium	5	2.6	2.6
Doxazosin	17	2.6	2.6
Pravastatin Sodium	12	2.6	2.6
Metoprolol Tartrate Injection	112	2.5	2.5
Latanoprost	30	2.5	2.5
Levetiracetam In Sodium Chloride	46	2.5	2.5
Levetiracetam Oral	46	2.5	2.5
Levetiracetam Injection	46	2.5	2.5
Tizanidine	14	2.5	2.5
Bendamustine Hcl	9	2.5	2.5
Oxybutynin Chloride	5	2.4	2.4
Sildenafil Citrate	69	2.3	2.3
Timolol	6	2.1	2.1
Levetiracetam	65	2.1	2.1
Pitavastatin Calcium	5	2.1	2.1
Rotigotine	7	2.1	2.1
Pancrelipase	18	2.0	2.0
Clozapine	57	1.9	1.9
Rifaximin	9	1.8	1.8
Sodium Oxybate	28	1.8	1.8
Paricalcitol	6	1.8	1.8
Tadalafil	42	1.8	1.8
Polatuzumab Vedotin	4	1.7	1.7
Hydrocodone Bitartrate	17	1.7	1.7
Mometasone Furoate And Formoterol Fumarate Dihydrate	6	1.6	1.6
Conjugated Estrogens And Medroxyprogesterone Acetate	9	1.6	1.6
Pseudoephedrine Hcl	4	1.5	1.5
Vortioxetine	6	1.5	1.5
Orlistat	9	1.5	1.5
Fentanyl Citrate	6	1.4	1.4
Romiplostim	5	1.4	1.4
Medroxyprogesterone Acetate	16	1.4	1.4
Suvorexant	4	1.3	1.3
Ranibizumab	8	1.3	1.3
Sacubitril And Valsartan	34	1.2	1.2
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	8	1.1	1.1
Paliperidone	6	1.1	1.1
Diroximel Fumarate	3	1.1	1.1
Minoxidil Foam 5% (Womens)	8	1.0	1.0
Rimegepant Sulfate	3	1.0	1.0
Minoxidil	8	0.8	0.8
Cinacalcet Hydrochloride	6	0.5	0.5
Evolocumab	20	0.5	0.5
Tirzepatide	17	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.