Reaction

Acute Pulmonary Oedema reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,546 reports · 293 co-occurring drugs

As of the last recalculation, Acute Pulmonary Oedema appears in 5,546 FAERS reports alongside 293 co-occurring drug terms. The strongest observed disproportionality signal is SEVOFLURANE (PRR 15.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Sevoflurane	35	15.9	16.0
Atropine	33	15.0	15.1
Atropine Sulfate	38	13.3	13.3
Paricalcitol	48	12.9	12.9
Magnesium Sulfate Heptahydrate	44	12.8	12.8
Magnesium Sulfate	44	12.7	12.8
Magnesium Sulfate In Water For	43	12.7	12.8
Propofol	121	12.7	12.7
Carfilzomib	79	10.6	10.6
Anti-Thymocyte Globulin (Rabbit)	22	10.3	10.3
Methoxy Polyethylene Glycol-Epoetin Beta	29	9.9	9.9
Posaconazole	40	9.3	9.3
Posaconazole Delayed-Release	27	9.3	9.3
Eplerenone	30	8.8	8.9
Oxazepam	50	8.8	8.8
Mesna Injection	17	7.7	7.8
Metolazone	23	7.7	7.7
Cefazolin	18	7.4	7.4
Basiliximab	23	7.4	7.4
Paroxetine Hydrochloride Hemihydrate	63	7.2	7.2
Mesna	16	7.2	7.2
Thiotepa	18	7.1	7.1
Itraconazole	22	7.1	7.1
Norepinephrine Bitartrate	27	7.1	7.1
Paroxetine	63	7.0	7.0
Misoprostol	18	7.0	7.0
Ceftriaxone	60	6.9	6.9
Cefuroxime	21	6.9	6.9
Nebivolol	29	6.9	6.9
Iohexol	15	6.8	6.8
Methimazole	14	6.7	6.7
Lopinavir And Ritonavir	24	6.7	6.7
Candesartan Cilexetil	46	6.6	6.6
Ceftriaxone Sodium	64	6.3	6.3
Furosemide	607	6.3	6.3
Captopril	16	6.3	6.3
Clobazam	40	6.2	6.2
Amiodarone Hydrochloride	18	6.0	6.1
Norepinephrine	17	6.0	6.0
Cefazolin Sodium	19	5.9	5.9
Labetalol	21	5.9	5.9
Dronedarone	16	5.9	5.9
Sevelamer Carbonate	18	5.9	5.9
Morphine	115	5.9	5.9
Methylprednisolone Sodium Succinate	72	5.9	5.9
Amikacin	26	5.7	5.7
Nifedipine	71	5.7	5.7
Midazolam	38	5.7	5.7
Bupivacaine	14	5.6	5.6
Spironolactone	204	5.6	5.6
Bisoprolol Fumarate	197	5.6	5.6
Valacyclovir	60	5.4	5.5
Digoxin	102	5.4	5.4
Everolimus Tablets	24	5.4	5.4
Azacitidine For	26	5.4	5.4
Midazolam Hydrochloride	38	5.3	5.3
Amoxicillin And Clavulanate Potassium	38	5.3	5.3
Nitroglycerin	73	5.2	5.2
Irbesartan	60	5.1	5.1
Azacitidine	39	5.0	5.0
Sodium Bicarbonate	30	4.9	4.9
Sodium Bicarbonate Injection,	30	4.9	4.9
Rifampicin	13	4.8	4.8
Isosorbide Dinitrate	25	4.8	4.8
Salmeterol Xinafoate	11	4.8	4.8
Rocuronium Bromide	15	4.8	4.8
Dextrose Monohydrate	17	4.8	4.8
Iron Sucrose	12	4.7	4.7
Piperacillin Sodium,Tazobactam Sodium	33	4.7	4.7
Heparin Sodium	17	4.7	4.7
Sulfamethoxazole And Trimethoprim	103	4.6	4.7
0Xygen	60	4.6	4.6
Oxygen	60	4.6	4.6
Erythropoietin	25	4.6	4.6
Dextrose	16	4.6	4.6
Insulin	67	4.6	4.6
Cytarabine	72	4.5	4.5
Temazepam	44	4.4	4.4
Enoxaparin Sodium	66	4.3	4.3
Leucovorin Calcium	22	4.3	4.3
Cyclophosphamide Injection, Solution	198	4.3	4.3
Cyclophosphamide	198	4.3	4.3
Cyclophosphamide For Injection	198	4.3	4.3
Fentanyl	111	4.3	4.3
Aprepitant	21	4.3	4.3
Trastuzumab	77	4.3	4.3
Piperacillin Sodium And Tazobactam Sodium	22	4.2	4.2
Enalapril	62	4.2	4.2
Desloratadine	12	4.2	4.2
Isosorbide Mononitrate	23	4.2	4.2
Daratumumab	44	4.2	4.2
Clopidogrel	213	4.2	4.2
Gemcitabine Hydrochloride	58	4.1	4.1
Piperacillin And Tazobactam	14	4.1	4.1
Meropenem	35	4.1	4.1
Haloperidol Lactate	27	4.1	4.1
Daptomycin	10	4.1	4.1
Gentamicin Sulfate	17	4.0	4.1
Glyburide	26	4.0	4.0
Ramipril	131	4.0	4.0
Haloperidol	26	4.0	4.0
Doxorubicin	94	4.0	4.0
Pyrazinamide	10	4.0	4.0
Bumetanide	28	4.0	4.0
Pravastatin Sodium	21	4.0	4.0
Doxorubicin Hydrochloride	34	3.9	3.9
Nebivolol Hydrochloride	35	3.9	3.9
Amphotericin B	13	3.9	3.9
Alemtuzumab	20	3.9	3.9
Pertuzumab	28	3.9	3.9
Vincristine Sulfate	30	3.9	3.9
Metoclopramide	56	3.9	3.9
Sotalol Hydrochloride	17	3.8	3.8
Fludarabine Phosphate	40	3.8	3.8
Quetiapine Fumarate	30	3.8	3.8
Enalapril Maleate	25	3.8	3.8
Lidocaine Hydrochloride And Epinephrine Bitartrate	53	3.8	3.8
Gentamicin	13	3.7	3.7
Gemcitabine	39	3.7	3.7
Vancomycin	57	3.7	3.7
Fondaparinux Sodium	8	3.7	3.7
Tramadol Hydrochloride	37	3.7	3.7
Paroxetine Hydrochloride	88	3.7	3.7
Pioglitazone	42	3.7	3.7
Mycophenolic Acid	31	3.6	3.7
Adrenalinum	40	3.6	3.6
Diltiazem Hydrochloride Extended-Release Tablets	11	3.6	3.6
Amphetamine	8	3.6	3.6
Lidicaine	47	3.6	3.6
Burn Relief	47	3.6	3.6
Imatinib	17	3.6	3.6
Allopurinol	148	3.6	3.6
Lidocaine Hydrochloride And Epinephrine	47	3.6	3.6
Ondansetron	104	3.6	3.6
Ondansetron Tablets	104	3.6	3.6
Methylprednisolone	131	3.6	3.6
Ondansetron Hydrochloride	116	3.6	3.6
Valacyclovir Hydrochloride	67	3.6	3.6
Ipratropium Bromide	34	3.6	3.6
Warfarin Sodium	44	3.6	3.6
Lidocaine, Menthol	47	3.6	3.6
Lidocaine Hydrochloride	57	3.6	3.6
Losartan Potassium And Hydrochlorothiazide	11	3.6	3.6
Sodium Chloride	74	3.5	3.6
Olanzapine	100	3.5	3.5
Vancomycin Hydrochloride	60	3.4	3.4
Potassium Chloride, Dextrose Monohydrate	84	3.4	3.4
Potassium Chloride Oral	84	3.4	3.4
Potassium Chloride Extended-Release	84	3.4	3.4
Pramipexole	14	3.4	3.4
Carvedilol	121	3.4	3.4
Lidocaine 4%	49	3.4	3.4
Sodium Chloride Tablet	66	3.4	3.4
Sodium Chloride Tablets	66	3.4	3.4
Sildenafil Powder,	32	3.4	3.4
Diazepam	107	3.3	3.3
Fluorouracil Cream, 0.5%	67	3.3	3.3
Bortezomib	78	3.3	3.3
Clopidogrel Bisulfate	89	3.3	3.3
Fluorouracil	67	3.3	3.3
Diltiazem Hydrochloride	30	3.3	3.3
Oxaliplatin	64	3.3	3.3
Alprazolam	175	3.3	3.3
Voriconazole	26	3.2	3.2
Ethyl Alcohol	23	3.2	3.2
Sacubitril And Valsartan	97	3.2	3.2
Lidocaine	49	3.2	3.2
Epoetin Alfa	10	3.2	3.2
Exemestane	18	3.2	3.2
Dexamethasone 1.5 Mg	239	3.2	3.2
Ketoprofen	11	3.2	3.2
Cyclosporine	92	3.1	3.1
Trazodone Hydrochloride	13	3.1	3.1
Dexamethasone	239	3.1	3.1
Etoposide	60	3.1	3.1
Bosentan	41	3.1	3.1
Zolpidem Tartrate	109	3.1	3.1
Potassium Chloride	92	3.1	3.1
Mirtazapine	74	3.1	3.1
Esomeprazole	50	3.0	3.0
Fosaprepitant Dimeglumine	11	3.0	3.0
Filgrastim	30	3.0	3.0
Fluoxetine	53	3.0	3.0
Metoclopramide Hydrochloride	61	3.0	3.0
Bicalutamide	12	3.0	3.0
Ticagrelor	25	3.0	3.0
Rituximab	161	2.9	2.9
Cefepime	11	2.9	2.9
Epoprostenol	10	2.9	2.9
Busulfan	12	2.9	2.9
Colchicine	20	2.9	2.9
Paclitaxel (Aibumin-Bound)	62	2.9	2.9
Melphalan Hydrochloride	19	2.9	2.9
Agalsidase Beta	7	2.8	2.8
Osimertinib	24	2.8	2.8
Cefepime Hydrochloride	12	2.8	2.8
Acetylcysteine	7	2.8	2.8
Isopropyl Alcohol	25	2.8	2.8
Isoniazid	12	2.8	2.8
Pemetrexed Disodium	28	2.8	2.8
Epinephrine	48	2.8	2.8
Atenolol	97	2.8	2.8
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	6	2.7	2.8
Everolimus	37	2.7	2.7
Sildenafil	42	2.7	2.7
Darbepoetin Alfa	39	2.7	2.7
Imatinib Mesylate	20	2.7	2.7
Paclitaxel	70	2.7	2.7
Bendamustine Hcl	11	2.7	2.7
Valsartan Oral	38	2.6	2.6
Irinotecan Hydrochloride	9	2.6	2.6
Voriconazole Injection	15	2.6	2.6
Valsartan	72	2.6	2.6
Brentuximab Vedotin	7	2.6	2.6
Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	6	2.5	2.5
Tranexamic Acid	6	2.5	2.5
Dasatinib	25	2.5	2.5
Bendamustine Hydrochloride	8	2.5	2.5
Eculizumab	36	2.5	2.5
Hydroxyurea	14	2.5	2.5
Abiraterone Acetate	27	2.5	2.5
Quetiapine	123	2.4	2.4
Alcohol	25	2.4	2.4
Warfarin	80	2.4	2.4
Bevacizumab	78	2.4	2.4
Metoprolol Tartrate	169	2.4	2.4
Vigabatrin	9	2.3	2.3
Melphalan	14	2.3	2.3
Chlorthalidone	7	2.3	2.3
Remdesivir	8	2.3	2.3
Thalidomide	22	2.3	2.3
Alteplase	9	2.3	2.3
Losartan Potassium	47	2.2	2.2
Metformin Hcl	33	2.2	2.2
Insulin Degludec	14	2.2	2.2
Dabigatran Etexilate	46	2.2	2.2
Ezetimibe And Simvastatin	9	2.2	2.2
Micafungin Sodium	5	2.2	2.2
Dabigatran Etexilate Mesylate	42	2.2	2.2
Carboplatin	73	2.2	2.2
Cisplatin	45	2.2	2.2
Sorafenib	12	2.2	2.2
Sunitinib Malate	22	2.1	2.1
Ritonavir	16	2.1	2.1
Methadone	23	2.0	2.0
Ritonavir 100 Mg	8	2.0	2.0
Sitagliptin And Metformin Hydrochloride	11	1.9	1.9
Docetaxel Anhydrous	34	1.9	1.9
Docetaxel	34	1.9	1.9
Inclisiran	4	1.9	1.9
Sildenafil Citrate	63	1.9	1.9
Prasugrel Hydrochloride	5	1.8	1.8
Atezolizumab	19	1.8	1.8
Pitavastatin Calcium	5	1.8	1.8
Rivastigmine	9	1.8	1.8
Linezolid	14	1.8	1.8
Romiplostim	7	1.7	1.7
Axitinib	9	1.7	1.7
Voclosporin	4	1.7	1.7
Venetoclax	28	1.7	1.7
Apixaban	30	1.7	1.7
Fentanyl Citrate	8	1.7	1.7
Entecavir	5	1.6	1.6
Ixazomib	12	1.6	1.6
Tolvaptan	6	1.6	1.6
Axicabtagene Ciloleucel	4	1.5	1.5
Blinatumomab	4	1.4	1.4
Cetuximab	12	1.4	1.4
Ranibizumab	10	1.4	1.4
Ravulizumab	5	1.4	1.4
Bosutinib	3	1.3	1.3
Vemurafenib	4	1.2	1.2
Nivolumab	32	1.2	1.2
Clozapine	40	1.2	1.2
Leuprolide Acetate	24	1.2	1.2
Eltrombopag Olamine	7	1.1	1.1
Pazopanib Hydrochloride	8	1.1	1.1
Abiraterone	4	1.1	1.1
Pseudoephedrine Hydrochloride	3	1.1	1.1
Ranitidine	58	1.1	1.1
Ranolazine	3	1.1	1.1
Pseudoephedrine Hcl	3	1.0	1.0
Aflibercept	8	1.0	1.0
Sofosbuvir	5	1.0	1.0
Ambrisentan	31	0.9	0.9
Durvalumab	5	0.9	0.9
Lenalidomide	101	0.9	0.9
Pomalidomide	23	0.8	0.8
Patiromer	3	0.8	0.8
Minoxidil Foam 5% (Womens)	6	0.7	0.7
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	5	0.6	0.6
Minoxidil	6	0.5	0.5
Cinacalcet Hydrochloride	6	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.