Reaction

Red Cell Distribution Width Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,104 reports · 331 co-occurring drugs

As of the last recalculation, Red Cell Distribution Width Increased appears in 4,104 FAERS reports alongside 331 co-occurring drug terms. The strongest observed disproportionality signal is ALEMTUZUMAB (PRR 55.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Alemtuzumab	202	55.7	56.2
Dimenhydrinate	113	55.3	55.9
Clozapine	471	21.4	21.4
Ado-Trastuzumab Emtansine	35	21.2	21.3
Niraparib	88	20.5	20.6
Ribociclib	124	20.5	20.6
Methylprednisolone Sodium Succinate	150	17.0	17.0
Fulvestrant	93	14.6	14.6
Cimetidine	27	14.3	14.3
Letrozole	165	14.1	14.1
Rabeprazole	59	13.7	13.7
Pertuzumab	72	13.7	13.7
Letrozole Tablets	121	13.1	13.1
Umeclidinium	23	13.1	13.1
Methylprednisolone	322	12.7	12.8
Methoxy Polyethylene Glycol-Epoetin Beta	27	12.5	12.5
Diphenhydramine Hydrochloride Capsule, Liquid Filled	50	12.0	12.0
Deferasirox	60	11.6	11.7
Rucaparib	20	11.5	11.6
Infliximab-Dyyb	63	11.1	11.1
Eculizumab	113	10.8	10.8
Ciclesonide	28	10.5	10.5
Diphenhydramine Hydrochloride	310	10.2	10.2
Torsemide	64	9.9	10.0
Rosuvastatin Calcium	54	9.8	9.9
Anastrozole Tablets	41	9.8	9.8
Dalteparin Sodium	20	9.6	9.6
Palbociclib	171	9.4	9.5
Standardized Senna Concentrate	23	9.3	9.3
Docusate Sodium 100Mg	43	9.2	9.2
Prochlorperazine	49	9.1	9.1
Fosaprepitant Dimeglumine	23	8.5	8.5
Lactulose	60	8.0	8.1
Fesoterodine Fumarate	17	8.0	8.0
Cyanocobalamin	51	7.9	7.9
Bisacodyl Suppositories	20	7.9	7.9
Polatuzumab Vedotin	15	7.8	7.8
Biscodyl	20	7.8	7.8
Methylprednisolone Acetate	12	7.6	7.6
Hydrocortisone Sodium Succinate	14	7.6	7.6
Candesartan	52	7.5	7.5
Sulfasalazine	112	7.4	7.4
Tranexamic Acid	13	7.4	7.4
Valproate Sodium	30	7.4	7.4
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	222	7.4	7.4
Anastrozole	52	7.3	7.3
Bisacodyl	20	7.2	7.2
Hydroxyurea	29	7.0	7.0
Acetaminophen Tablet Extended Release	325	6.9	6.9
Pain Reliever	325	6.9	6.9
Acetaminophen 500Mg	325	6.9	6.9
Aprepitant	25	6.9	6.9
Docusate Sodium	77	6.9	6.9
Diphenhydramine	84	6.9	6.9
Bendamustine Hydrochloride	16	6.8	6.8
Hydroxychloroquine Sulfate	119	6.8	6.8
Eplerenone	17	6.8	6.8
Exemestane	28	6.7	6.7
Sevelamer Carbonate	15	6.6	6.6
Prochlorperazine Maleate	12	6.6	6.6
Leflunomide	132	6.6	6.6
Instalax Polyethylene Glycol 3350	16	6.6	6.6
Ferrous Sulfate	63	6.4	6.5
Acetaminophen	508	6.4	6.4
Polyethylene Glycol 400	16	6.4	6.4
Diphenhydramine Hcl	14	6.4	6.4
Lithium Carbonate	21	6.3	6.3
Ruxolitinib	87	6.3	6.3
Trastuzumab	83	6.2	6.2
Dextrose	16	6.2	6.2
Dapagliflozin	38	6.2	6.2
Folic Acid	283	6.1	6.1
Nicotine Polacrilex Mini	18	6.1	6.1
Nicotine Polarilex	18	6.1	6.1
Bisoprolol Fumarate	158	6.1	6.1
Dextrose Monohydrate	16	6.1	6.1
Posaconazole Delayed-Release	13	6.0	6.0
Zoledronic Acid	47	6.0	6.0
Docusate Sodium - Sennosides	37	5.9	5.9
Naproxen	89	5.9	5.9
Vincristine Sulfate	33	5.7	5.8
Aripiprazole Oral	46	5.7	5.7
Aripiprazole Orally Disintegrating	46	5.7	5.7
Valsartan Oral	60	5.7	5.7
Ravulizumab	15	5.6	5.7
Doxorubicin Hydrochloride	36	5.6	5.6
Colchicine	29	5.6	5.6
Magnesium Sulfate In Water For	14	5.6	5.6
Prednisone	492	5.5	5.5
Sodium Bicarbonate	25	5.5	5.5
Sodium Bicarbonate Injection,	25	5.5	5.5
Magnesium Sulfate Heptahydrate	14	5.5	5.5
Sennosides	32	5.5	5.5
Magnesium Sulfate	14	5.5	5.5
Pantoprazole	258	5.4	5.5
Bevacizumab	129	5.4	5.4
Risedronate Sodium	33	5.4	5.4
Sennosides 8.6 Mg Tablets	22	5.3	5.4
Posaconazole	17	5.3	5.3
Senna	22	5.3	5.3
Goserelin	14	5.3	5.3
Lorazepam	181	5.3	5.3
Magnesium Hydroxide	14	5.3	5.3
Antacid	49	5.3	5.3
Tocilizumab	116	5.3	5.3
Ascorbic Acid	24	5.3	5.3
Chlorthalidone	12	5.3	5.3
Alpelisib	9	5.2	5.3
Crizotinib	13	5.2	5.2
Potassium Chloride, Dextrose Monohydrate	93	5.2	5.2
Potassium Chloride Oral	93	5.2	5.2
Potassium Chloride Extended-Release	93	5.2	5.2
Valproic Acid	32	5.2	5.2
Acyclovir	114	5.2	5.2
Methimazole	8	5.2	5.2
Terazosin Hydrochloride	9	5.1	5.1
Testosterone Cypionate	9	5.1	5.1
Nebivolol	16	5.1	5.1
Hydrocortisone	88	5.1	5.1
Doxyclycline Hyclate	17	5.1	5.1
Ramipril	121	5.1	5.1
Dronabinol	8	5.1	5.1
Cetirizine Hydrochloride Allergy	30	5.1	5.1
Cetirizine Hydrochloride Tablets	30	5.1	5.1
Glyburide	24	5.1	5.1
Escitslopram	57	5.0	5.0
Hydrocortisone Acetate	71	5.0	5.0
Sucralfate Oral	14	5.0	5.0
Sucralfate Oral Suspension	14	5.0	5.0
Anti-Itch	65	5.0	5.0
Anti-Pruritic	65	5.0	5.0
Antipruritic (Anti-Itch)	65	5.0	5.0
Cool Relief Gel With Aloe	65	5.0	5.0
Drs. Hydrocortisone	65	5.0	5.0
Hydrocortisone Continuous Spray	65	5.0	5.0
Hydrocortisone Spray	65	5.0	5.0
Anti-Itch Cream	65	5.0	5.0
Hydrocortisone Lotion	65	5.0	5.0
Hydrocortisone Cream 1%	65	5.0	5.0
Hydrocortisone Cream 1/2%	65	5.0	5.0
Hydrocortisone 1%	65	5.0	5.0
Metolazone	11	5.0	5.0
Rituximab	199	5.0	5.0
Ticagrelor	31	5.0	5.0
Hydrocortisone Cream	65	5.0	5.0
Erythropoietin	20	5.0	5.0
Magnesium	79	5.0	5.0
Bendamustine Hcl	15	4.9	4.9
Insulin Glargine-Yfgn	21	4.9	4.9
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	29	4.9	4.9
Blinatumomab	10	4.9	4.9
Duloxetine	66	4.9	4.9
Rabeprazole Sodium	26	4.9	4.9
Senna Leaf	22	4.9	4.9
Nilotinib	28	4.8	4.8
Diphenoxylate Hydrochloride And Atropine Sulfate	13	4.8	4.8
Piperacillin Sodium,Tazobactam Sodium	25	4.8	4.8
Escitalopram Oxalate	68	4.8	4.8
Fluticasone Propionate And Salmeterol Xinafoate	56	4.8	4.8
Potassium Chloride	104	4.7	4.7
Ergocalciferol	335	4.7	4.7
Allopurinol	140	4.7	4.7
Nystatin	25	4.7	4.7
Oxybutynin Chloride	8	4.6	4.6
Psyllium Husk	9	4.6	4.6
Asfotase Alfa	9	4.6	4.6
Gemcitabine	35	4.5	4.5
Amiodarone Hydrochloride	10	4.5	4.5
Bosutinib	8	4.5	4.5
Calcium Carbonate	59	4.5	4.5
Insulin Glulisine	9	4.5	4.5
Nystatin Ointment	23	4.5	4.5
Nystatin Cream	23	4.5	4.5
Bumetanide	23	4.4	4.4
Melatonin	47	4.4	4.4
Magnesium Oxide	36	4.4	4.4
Romiplostim	13	4.4	4.4
Esomeprazole	53	4.4	4.4
Olanzapine	91	4.4	4.4
Obinutuzumab	14	4.3	4.3
Hydromorphone Hydrochloride	77	4.3	4.3
Ondansetron Hydrochloride	102	4.3	4.3
Ondansetron	91	4.3	4.3
Ondansetron Tablets	91	4.3	4.3
Iron	56	4.3	4.3
Metformin Hydrochloride Tablets	48	4.3	4.3
Metformin Hydrochloride Extended-Release Tablets	48	4.3	4.3
Metformin Hydrochloride Tablet	48	4.3	4.3
Tofacitinib Citrate	11	4.3	4.3
Sucralfate	20	4.2	4.3
Biotin	26	4.2	4.2
Albuterol Sulfate	237	4.2	4.2
Cholestyramine	10	4.2	4.2
Isosorbide Mononitrate	17	4.2	4.2
Fingolimod Hcl	70	4.2	4.2
Metformin Hydrochloride	48	4.2	4.2
Gemcitabine Hydrochloride	43	4.1	4.1
Olaparib	17	4.1	4.1
Baclofen	69	4.1	4.1
Fluorouracil	62	4.1	4.1
Fluorouracil Cream, 0.5%	61	4.1	4.1
Spironolactone	111	4.1	4.1
Ranitidine	155	4.1	4.1
Felodipine Extended-Release Tablets	9	4.0	4.0
Felodipine	9	4.0	4.0
Mesalamine	44	4.0	4.0
Naproxen Sodium	110	4.0	4.0
Piperacillin And Tazobactam	10	4.0	4.0
Furosemide	294	3.9	3.9
Everolimus	39	3.9	3.9
Ciprofloxacin Hydrochloride And Hydrocortisone	16	3.9	3.9
Linagliptin	14	3.9	3.9
Cetirizine	59	3.9	3.9
Methotrexate Sodium	349	3.9	3.9
Thalidomide	28	3.9	3.9
Tafamidis	9	3.9	3.9
Meloxicam	44	3.9	3.9
Fluticasone Propionate Nasal	23	3.9	3.9
Methotrexate	302	3.8	3.9
Insulin	42	3.8	3.9
Loperamide Hydrochloride And Dimethicone	24	3.8	3.8
Irbesartan	33	3.8	3.8
Sodium Chloride Tablet	54	3.8	3.8
Sodium Chloride Tablets	54	3.8	3.8
Budesonide And Formoterol Fumarate Dihydrate	71	3.8	3.8
Tamsulosin Hydrochloride	15	3.7	3.7
Warfarin	92	3.7	3.7
Hydroxychloroquine	54	3.7	3.7
Escitalopram	100	3.7	3.7
Human Insulin	9	3.7	3.7
Piperacillin Sodium And Tazobactam Sodium	14	3.6	3.6
Mesna	6	3.6	3.6
Metformin	242	3.6	3.6
Ceftriaxone Sodium	27	3.6	3.6
Atorvastatin Calcium, Film Coated	49	3.6	3.6
Ifosfamide	15	3.6	3.6
Omalizumab	59	3.5	3.5
Cefepime	10	3.5	3.5
Loperamide Hydrochloride	31	3.5	3.5
Metoclopramide	38	3.5	3.5
Metformin Er 500 Mg	202	3.5	3.5
Metformin Er 750 Mg	202	3.5	3.5
Eltrombopag Olamine	16	3.5	3.5
Sodium Chloride	54	3.5	3.5
Niacin	8	3.5	3.5
Lisinopril And Hydrochlorothiazide	7	3.5	3.5
Imatinib	12	3.5	3.5
Famotidine	79	3.5	3.5
Warfarin Sodium	31	3.4	3.4
Doxorubicin	58	3.3	3.3
Fluticasone Propionate	84	3.3	3.3
Atorvastatin Calcium	157	3.3	3.3
Rosuvastatin	130	3.3	3.3
Amantadine	10	3.3	3.3
Metoclopramide Hydrochloride	49	3.2	3.2
Carboxymethylcellulose Sodium	6	3.2	3.2
Empagliflozin	42	3.2	3.2
Cefepime Hydrochloride	10	3.2	3.2
Metoroprolol Tartrate	40	3.1	3.1
Encorafenib	6	3.1	3.1
Mesna Injection	5	3.1	3.1
Regorafenib	7	3.1	3.1
Nicotine	24	3.0	3.0
Aripiprazole	72	3.0	3.0
Naproxen Sodium Tablet, Coated	8	3.0	3.0
Naproxen Sodium, Coated Tablets	8	3.0	3.0
Naproxen Sodium 220Mg	8	3.0	3.0
Dalfampridine	42	3.0	3.0
Oxybutynin	17	3.0	3.0
Imatinib Mesylate	16	2.9	2.9
Granisetron	6	2.9	2.9
Infliximab	121	2.9	2.9
Capecitabine	51	2.8	2.9
Cisplatin	43	2.8	2.8
Tolvaptan	8	2.8	2.8
Nicotine Polacrilex	21	2.8	2.8
Polyethylene Glycol 3350	52	2.8	2.8
Tofacitinib	99	2.8	2.8
Desoximetasone	10	2.7	2.7
Docetaxel Anhydrous	35	2.6	2.6
Docetaxel	35	2.6	2.6
Cladribine	5	2.6	2.6
Latanoprost	26	2.6	2.6
Mirabegron	20	2.6	2.6
Cyclophosphamide Injection, Solution	90	2.6	2.6
Cyclophosphamide	90	2.6	2.6
Cyclophosphamide For Injection	90	2.6	2.6
Abatacept	70	2.6	2.6
Somatropin	37	2.6	2.6
Trametinib	12	2.5	2.5
Avapritinib	6	2.5	2.5
Acetaminophen And Codeine	6	2.5	2.5
Carboplatin	62	2.5	2.5
Cortisone Acetate	6	2.5	2.5
Desvenlafaxine Succinate	13	2.4	2.4
Dexamethasone 1.5 Mg	138	2.4	2.4
Diclofenac Potassium, Film Coated	4	2.4	2.4
Diclofenac Potassium Tablets	4	2.4	2.4
Icosapent Ethyl	4	2.4	2.4
Irinotecan Hydrochloride	6	2.4	2.4
Lutetium Lu 177 Vipivotide Tetraxetan	6	2.3	2.3
Pazopanib Hydrochloride	12	2.3	2.3
Belimumab	14	2.2	2.2
Vilazodone Hydrochloride	4	2.2	2.2
Oxaliplatin	32	2.2	2.2
Darbepoetin Alfa	23	2.2	2.2
Dabrafenib	9	2.2	2.2
Sacubitril And Valsartan	47	2.1	2.1
Medroxyprogesterone Acetate	20	2.0	2.0
Alteplase	6	2.0	2.0
Denosumab	80	2.0	2.0
Fam-Trastuzumab Deruxtecan-Nxki	4	2.0	2.0
Secukinumab	63	2.0	2.0
Ustekinumab	40	2.0	2.0
Vedolizumab	33	2.0	2.0
Sunitinib Malate	15	1.9	1.9
Pembrolizumab	40	1.9	1.9
Azacitidine	11	1.9	1.9
Diclofenac Potassium	4	1.9	1.9
Abemaciclib	7	1.8	1.8
Pegfilgrastim	34	1.8	1.8
Paliperidone	8	1.7	1.7
Lenvatinib	11	1.7	1.7
Azacitidine For	6	1.7	1.7
Carfilzomib	9	1.6	1.6
Venetoclax	18	1.5	1.5
Dasatinib	10	1.4	1.4
Apremilast	39	1.4	1.4
Erenumab-Aooe	13	1.2	1.2
Pirfenidone	9	1.1	1.1
Paliperidone Palmitate	6	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.