Reaction

Which drugs are most reported with Hypertransaminasaemia?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,725 reports · 411 co-occurring drugs

As of the last recalculation, Hypertransaminasaemia appears in 6,725 FAERS reports alongside 411 co-occurring drug terms. The strongest observed disproportionality signal is PYRAZINAMIDE (PRR 22.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Pyrazinamide	68	22.6	22.8
Tofacitinib Citrate	75	17.9	18.0
Remdesivir	71	16.7	16.7
Pseudoephedrine Hydrochloride	54	16.4	16.5
Pemetrexed	109	16.0	16.1
Calcium Gluconate	61	15.8	15.9
Pseudoephedrine Hcl	54	15.3	15.4
Gemcitabine	186	15.0	15.1
Lopinavir And Ritonavir	63	14.5	14.6
Cortisone Acetate	57	14.4	14.5
Rifampin	67	14.3	14.4
Gemcitabine Hydrochloride	236	14.2	14.3
Isoniazid	73	14.1	14.1
Ado-Trastuzumab Emtansine	38	14.0	14.1
Piperacillin And Tazobactam	57	13.9	14.0
Linezolid	127	13.4	13.5
Pemetrexed Disodium	152	12.6	12.7
Naproxen Sodium Tablet, Coated	54	12.4	12.5
Naproxen Sodium, Coated Tablets	54	12.4	12.5
Naproxen Sodium 220Mg	54	12.4	12.5
Piperacillin Sodium,Tazobactam Sodium	100	11.8	11.9
Diclofenac Potassium, Film Coated	32	11.8	11.9
Diclofenac Potassium Tablets	32	11.8	11.9
Voriconazole Injection	80	11.5	11.6
Ceftriaxone	119	11.4	11.4
Paclitaxel	325	10.6	10.7
Paclitaxel (Aibumin-Bound)	263	10.3	10.3
Ceftriaxone Sodium	125	10.3	10.3
Pegaspargase	40	10.2	10.2
Desoximetasone	62	10.2	10.2
Rifampicin	33	10.1	10.2
Piperacillin Sodium And Tazobactam Sodium	62	9.9	9.9
Anakinra	52	9.8	9.8
Diclofenac Potassium	33	9.5	9.5
Diltiazem Hydrochloride Extended-Release Tablets	33	9.0	9.0
Carboplatin	351	9.0	9.0
Ribociclib	90	8.9	9.0
Moxifloxacin	40	8.8	8.9
Voriconazole	84	8.7	8.7
Mercaptopurine	48	8.6	8.6
Moxifloxacin Hydrochloride	56	8.6	8.6
Pembrolizumab	280	8.6	8.6
Meropenem	87	8.5	8.5
Norepinephrine Bitartrate	38	8.2	8.2
Amphotericin B	32	7.9	8.0
Pertuzumab	69	7.9	7.9
Adalimumab-Fkjp	114	7.7	7.7
Adalimumab-Aaty	116	7.7	7.7
Atezolizumab	94	7.6	7.6
Midazolam	61	7.5	7.6
Ganciclovir Sodium	25	7.3	7.4
Ganciclovir	24	7.3	7.3
Adalimumab-Adaz	121	7.2	7.2
Midazolam Hydrochloride	62	7.2	7.2
Micafungin Sodium	19	7.0	7.0
Azithromycin	89	6.9	6.9
Risedronate Sodium	68	6.8	6.8
Trastuzumab	147	6.8	6.8
Azithromycin Monohydrate	89	6.7	6.7
Quetiapine Fumarate	62	6.6	6.6
Irinotecan Hydrochloride	27	6.5	6.5
Sarilumab	55	6.5	6.5
Norepinephrine	22	6.4	6.4
Ipilimumab	88	6.4	6.4
Cefepime Hydrochloride	33	6.4	6.4
Crizotinib	26	6.4	6.4
Cetirizine Hydrochloride Allergy	61	6.3	6.3
Cetirizine Hydrochloride Tablets	61	6.3	6.3
Hydrocortisone Sodium Succinate	19	6.3	6.3
Blinatumomab	21	6.2	6.3
Fluorouracil Cream, 0.5%	150	6.2	6.2
Tobramycin Solution	24	6.2	6.2
Etoposide	144	6.2	6.2
Cyanocobalamin	65	6.2	6.2
Fluorouracil	150	6.1	6.1
Tobramycin Sulfate	24	6.0	6.0
Fulvestrant	62	5.9	5.9
Doxorubicin	165	5.9	5.9
Cefepime	27	5.8	5.9
Vincristine Sulfate	55	5.8	5.9
Amikacin	32	5.8	5.8
Hydrocortisone Acetate	134	5.8	5.8
Tocilizumab	207	5.8	5.8
Canakinumab	20	5.7	5.7
Anti-Itch	122	5.7	5.7
Anti-Pruritic	122	5.7	5.7
Antipruritic (Anti-Itch)	122	5.7	5.7
Cool Relief Gel With Aloe	122	5.7	5.7
Drs. Hydrocortisone	122	5.7	5.7
Hydrocortisone Continuous Spray	122	5.7	5.7
Hydrocortisone Spray	122	5.7	5.7
Anti-Itch Cream	122	5.7	5.7
Hydrocortisone Lotion	122	5.7	5.7
Hydrocortisone Cream 1%	122	5.7	5.7
Hydrocortisone Cream 1/2%	122	5.7	5.7
Hydrocortisone 1%	122	5.7	5.7
Levetiracetam In Sodium Chloride	140	5.7	5.7
Levetiracetam Oral	140	5.7	5.7
Levetiracetam Injection	140	5.7	5.7
Hydrocortisone Cream	122	5.7	5.7
Doxyclycline Hyclate	31	5.7	5.7
Ifosfamide	39	5.6	5.7
Abemaciclib	36	5.6	5.6
Human Immunoglobulin G	37	5.6	5.6
Diclofenac Sodium 1%	63	5.5	5.5
Diclofenac Sodium Topical	63	5.5	5.5
Diclofenac Sodium Topical Gel, 1%	63	5.5	5.5
Icosapent Ethyl	15	5.5	5.5
Letrozole Tablets	84	5.5	5.5
Hydroxychloroquine	129	5.4	5.4
Nivolumab	165	5.4	5.4
Daptomycin	16	5.4	5.4
Oxaliplatin	124	5.3	5.3
Mycophenolate Mofetil	224	5.2	5.3
Mycophenolate Mofetil Hydrochloride	224	5.2	5.2
Cabozantinib	80	5.2	5.2
Acetaminophen Tablet Extended Release	407	5.2	5.2
Pain Reliever	407	5.2	5.2
Acetaminophen 500Mg	407	5.2	5.2
Enoxaparin Sodium	95	5.2	5.2
Methylprednisolone	223	5.1	5.1
Acetaminophen And Codeine	20	5.1	5.1
Azithromycin Dihydrate	95	5.1	5.1
Doxorubicin Hydrochloride	53	5.1	5.1
Dextrose	21	4.9	5.0
Acetylcysteine	15	4.9	4.9
Cyclophosphamide Injection, Solution	272	4.9	4.9
Cyclophosphamide	272	4.9	4.9
Cyclophosphamide For Injection	272	4.9	4.9
Gemfibrozil	24	4.9	4.9
Obinutuzumab	26	4.9	4.9
Dextrose Monohydrate	21	4.9	4.9
Diphenhydramine Hydrochloride Capsule, Liquid Filled	33	4.8	4.8
Antacid	73	4.8	4.8
Hydrocortisone	135	4.8	4.8
Valproic Acid	48	4.7	4.7
Ketoprofen	20	4.7	4.7
Amiodarone Hydrochloride	17	4.7	4.7
Isopropyl Alcohol	51	4.7	4.7
Letrozole	92	4.7	4.7
Doxycycline Hyclate	100	4.6	4.6
Cytarabine	89	4.6	4.6
Doxycycline	100	4.6	4.6
Dexamethasone Sodium Phosphate	15	4.6	4.6
Temozolomide	31	4.6	4.6
Calcium Carbonate	97	4.5	4.5
Posaconazole Delayed-Release	16	4.5	4.5
Itraconazole	17	4.5	4.5
Lapatinib	22	4.4	4.4
Magnesium Sulfate In Water For	18	4.4	4.4
Levetiracetam	184	4.4	4.4
Lumacaftor And Ivacaftor	12	4.3	4.3
Leflunomide	143	4.3	4.3
Magnesium Sulfate Heptahydrate	18	4.3	4.3
Phenobarbital	20	4.3	4.3
Magnesium Sulfate	18	4.3	4.3
Sodium Bicarbonate	32	4.3	4.3
Sodium Bicarbonate Injection,	32	4.3	4.3
Levofloxacin	82	4.2	4.3
Levofloxacin In 5% Dextrose	82	4.2	4.3
Sulfasalazine	105	4.2	4.2
Aprepitant	25	4.2	4.2
Posaconazole	22	4.2	4.2
Tretinoin	11	4.2	4.2
Pantoprazole Sodium In 0.9% Sodium Chloride	83	4.2	4.2
Pantoprazole Sodium Injection	83	4.2	4.2
Docetaxel Anhydrous	90	4.2	4.2
Docetaxel	90	4.2	4.2
Phenytoin	28	4.2	4.2
Ranolazine	14	4.2	4.2
Sirolimus	18	4.1	4.1
Axitinib	26	4.1	4.1
Alcohol	51	4.1	4.1
Propofol	48	4.1	4.1
Axicabtagene Ciloleucel	13	4.1	4.1
Chlorhexidine Gluconate	12	4.1	4.1
Fluconazole	91	4.1	4.1
Methotrexate Sodium	590	4.0	4.0
Colchicine	34	4.0	4.0
Erythromycin	24	4.0	4.0
Dexamethasone 1.5 Mg	358	3.9	3.9
Lacosamide	47	3.9	3.9
Dexamethasone	359	3.9	3.9
Ramipril	153	3.9	3.9
Fludarabine Phosphate	48	3.8	3.8
Panitumumab	19	3.8	3.8
Cetiirizine	51	3.7	3.8
Cetirizine	93	3.7	3.8
Methotrexate	482	3.7	3.7
Atropine	10	3.7	3.7
Clobazam	29	3.7	3.7
Ondansetron	128	3.7	3.7
Ondansetron Tablets	128	3.7	3.7
Rituximab	244	3.7	3.7
Abiraterone	16	3.6	3.6
Fosaprepitant Dimeglumine	16	3.6	3.6
Haloperidol	28	3.6	3.6
Thiotepa	11	3.6	3.6
Zoledronic Acid	46	3.6	3.6
Methimazole	9	3.6	3.6
Melphalan	26	3.5	3.6
Hydroxychloroquine Sulfate	103	3.5	3.5
Haloperidol Lactate	28	3.5	3.5
Nebivolol	18	3.5	3.5
Osimertinib	36	3.5	3.5
Terbinafine Hydrochloride	10	3.5	3.5
Thiamine Hydrochloride	14	3.5	3.5
Methylprednisolone Acetate	9	3.5	3.5
Minocycline	13	3.5	3.5
Ondansetron Hydrochloride	133	3.4	3.4
Cisplatin	85	3.4	3.4
Pantoprazole	270	3.4	3.4
Bendamustine Hydrochloride	13	3.4	3.4
Lorazepam	191	3.4	3.4
Tobramycin	26	3.4	3.4
Vemurafenib	13	3.4	3.4
Melphalan Hydrochloride	27	3.3	3.3
Brentuximab Vedotin	11	3.3	3.3
Vancomycin Hydrochloride	70	3.3	3.3
Tramadol Hydrochloride	40	3.3	3.3
Mycophenolic Acid	34	3.3	3.3
Sucralfate Oral	15	3.3	3.3
Sucralfate Oral Suspension	15	3.3	3.3
Naproxen	82	3.3	3.3
Prednisolone	186	3.3	3.3
Prednisolone Oral	186	3.3	3.3
Prednisolone Oral Solution	186	3.3	3.3
Diltiazem Hydrochloride	36	3.2	3.2
Diclofenac	89	3.2	3.2
Meloxicam	60	3.2	3.2
Azathioprine	90	3.2	3.2
Acetaminophen	439	3.2	3.2
Vancomycin	58	3.1	3.1
Ibuprofen Capsule	197	3.1	3.1
Ibuprofen Tablet, Film Coated	197	3.1	3.1
Ibupfrofen	197	3.1	3.1
Ibuprofen Tablets Usp, 200Mg	197	3.1	3.1
Ibuprofen Oral	197	3.1	3.1
Ibuprofen Capsules 200 Mg	197	3.1	3.1
Ibuprofen 200 Mg	197	3.1	3.1
Ibuprofen 200Mg	197	3.1	3.1
Capecitabine	91	3.1	3.1
Anti-Thymocyte Globulin (Rabbit)	8	3.1	3.1
Sulfamethoxazole And Trimethoprim	83	3.1	3.1
Fondaparinux Sodium	8	3.1	3.1
Pancrelipase	38	3.1	3.1
Cefazolin	9	3.1	3.1
Valganciclovir Hydrochloride Powder,	12	3.0	3.1
Dutasteride	8	3.0	3.0
Bevacizumab	120	3.0	3.0
Ursosiol	19	3.0	3.0
Bleomycin Sulfate	10	3.0	3.0
Bendamustine Hcl	15	3.0	3.0
Instalax Polyethylene Glycol 3350	12	3.0	3.0
Botulinum Toxin Type A	12	3.0	3.0
Ursodiol	21	3.0	3.0
Standardized Senna Concentrate	12	3.0	3.0
Polyethylene Glycol 400	12	2.9	2.9
Levothyroxine Sodium Anhydrous	94	2.9	2.9
Lithium Carbonate	16	2.9	2.9
Leucovorin Calcium	18	2.9	2.9
Durvalumab	19	2.9	2.9
Magnesium	76	2.9	2.9
Atropine Sulfate	10	2.9	2.9
Polatuzumab Vedotin	9	2.9	2.9
Lamotirigine	65	2.8	2.8
Lamotrigine Extended-Release	65	2.8	2.8
Lamotrigine Chewable Dispersible	65	2.8	2.8
Imatinib	16	2.8	2.8
Prednisone	436	2.8	2.8
Cyclosporine	99	2.8	2.8
Fam-Trastuzumab Deruxtecan-Nxki	9	2.8	2.8
Bosutinib	8	2.8	2.8
Busulfan	14	2.8	2.8
Tacrolimus Ointment 0.1%	109	2.7	2.7
Tacrolimus Extended-Release Capsules	109	2.7	2.7
Azacitidine For	16	2.7	2.7
Allopurinol	135	2.7	2.7
Valproate Sodium	18	2.7	2.7
Valacyclovir	36	2.7	2.7
Basiliximab	10	2.6	2.6
Mesna Injection	7	2.6	2.6
Exemestane	18	2.6	2.6
Everolimus Tablets	14	2.6	2.6
Mesna	7	2.6	2.6
Olanzapine	88	2.6	2.6
Golimumab	70	2.5	2.5
Triamcinolone Acetonide Ointment Usp, 0.05%	19	2.5	2.5
Romiplostim	12	2.5	2.5
Oxazepam	17	2.5	2.5
Vitamin C	72	2.4	2.4
Lisinopril And Hydrochlorothiazide	8	2.4	2.4
Eltrombopag Olamine	18	2.4	2.4
Brivaracetam	7	2.4	2.4
Mycophenilic Acid	16	2.4	2.4
Entecavir	9	2.4	2.4
Ustekinumab	78	2.4	2.4
Gentamicin	10	2.4	2.4
Omeprazole	258	2.4	2.4
Bisoprolol Fumarate	103	2.4	2.4
Lenvatinib	25	2.4	2.4
Ibuprofen	203	2.4	2.4
Lansoprazole	132	2.3	2.3
Tacrolimus	116	2.3	2.3
Cefazolin Sodium	9	2.3	2.3
Atovaquone	6	2.3	2.3
Acalabrutinib	9	2.3	2.3
Pazopanib Hydrochloride	20	2.3	2.3
Fesoterodine Fumarate	8	2.3	2.3
Ezetimibe	55	2.3	2.3
Nintedanib	23	2.3	2.3
Nitrofurantoin	12	2.3	2.3
Palbociclib	69	2.3	2.3
Prochlorperazine	20	2.2	2.2
Abacavir Sulfate	7	2.2	2.2
Nitrofurantoin (Monohydrate/Macrocrystals)	12	2.2	2.2
Deferasirox	19	2.2	2.2
Dabrafenib	15	2.2	2.2
Sodium Chloride Tablet	52	2.2	2.2
Sodium Chloride Tablets	52	2.2	2.2
Encorafenib	7	2.2	2.2
Naproxen Sodium	100	2.2	2.2
Acyclovir	80	2.2	2.2
Sodium Chloride	55	2.2	2.2
Gentamicin Sulfate	11	2.2	2.2
Filgrastim	26	2.1	2.1
Bortezomib	61	2.1	2.1
Fish Oil	61	2.1	2.1
Ketoconazole Foam	10	2.1	2.1
Lithium	17	2.1	2.1
Lithium Bromatum	17	2.1	2.1
Ketoconazole Cream, 2%	10	2.1	2.1
Tizanidine	16	2.1	2.1
Quetiapine	128	2.1	2.1
Clarithromycin	23	2.1	2.1
Olmesartan Medoxomil	24	2.1	2.1
Hydroxyurea	14	2.1	2.1
Diclofenac Sodium	97	2.0	2.0
Elexacaftor, Tezacaftor, And Ivacaftor	8	2.0	2.0
Cannabidiol	15	2.0	2.0
Rosuvastatin	128	2.0	2.0
Ivacaftor	5	1.9	1.9
Cetirizine Hydrochloride	103	1.9	1.9
Oseltamivir	5	1.9	1.9
Baricitinib	6	1.9	1.9
Trametinib	15	1.9	1.9
Cabotegravir	5	1.9	1.9
Certolizumab Pegol	72	1.9	1.9
Triamcinolone Acetonide	19	1.9	1.9
Sofosbuvir	12	1.9	1.9
Azacitidine	18	1.9	1.9
Apalutamide	7	1.8	1.8
Nebivolol Hydrochloride	20	1.8	1.8
Atomoxetine Hydrochloride	14	1.8	1.8
Loperamide Hydrochloride Oral	6	1.8	1.8
Atorvastatin Calcium, Film Coated	41	1.8	1.8
Oxcarbazepine	19	1.8	1.8
Abiraterone Acetate	24	1.8	1.8
Interferon Beta-1B	11	1.8	1.8
Abatacept	78	1.8	1.8
Apremilast	81	1.7	1.7
Oxycodone	103	1.7	1.7
Gefitinib	5	1.7	1.7
Lamivudine Oral	14	1.7	1.7
Tolvaptan	8	1.7	1.7
Secukinumab	88	1.7	1.7
Alteplase	8	1.6	1.7
Olaparib	11	1.6	1.6
Cladribine	5	1.6	1.6
Erlotinib	5	1.6	1.6
Dornase Alfa	10	1.6	1.6
Isotretinoin	25	1.6	1.6
Upadacitinib	40	1.5	1.5
Dronedarone	5	1.5	1.5
Ixazomib	14	1.5	1.5
Dasatinib	18	1.5	1.5
Sorafenib	10	1.5	1.5
Ethyl Alcohol	13	1.5	1.5
Ruxolitinib	34	1.5	1.5
Ocrelizumab	29	1.4	1.4
Thalidomide	17	1.4	1.4
Tofacitinib	85	1.4	1.4
Empagliflozin	31	1.4	1.4
Alpelisib	4	1.4	1.4
Daratumumab	18	1.4	1.4
Oseltamivir Phosphate	11	1.4	1.4
Cetuximab	14	1.4	1.4
Venetoclax	27	1.4	1.4
Cariprazine	4	1.3	1.3
Erenumab-Aooe	23	1.3	1.3
Denosumab	84	1.3	1.3
Ranitidine Hydrochloride	22	1.3	1.3
Erlotinib Hydrochloride	5	1.2	1.2
Fentanyl Citrate	7	1.2	1.2
Bimatoprost	11	1.2	1.2
Lutetium Lu 177 Vipivotide Tetraxetan	5	1.2	1.2
Iohexol	3	1.1	1.1
Sevoflurane	3	1.1	1.1
Selinexor	3	1.1	1.1
Voclosporin	3	1.1	1.1
Vismodegib	3	1.0	1.0
Leuprolide Acetate	26	1.0	1.0
Dalfampridine	22	0.9	0.9
Brexpiprazole	5	0.9	0.9
Carfilzomib	8	0.9	0.9
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	4	0.7	0.7
Dimethyl Fumarate	25	0.6	0.6
Pegfilgrastim	20	0.6	0.6
Voxelotor	4	0.6	0.6
Nirmatrelvir And Ritonavir	7	0.4	0.4
Salicylic Acid	6	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.