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Which drugs are most reported with Hiccups?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 8,050 reports · 375 co-occurring drugs

As of the last recalculation, Hiccups appears in 8,050 FAERS reports alongside 375 co-occurring drug terms. The strongest observed disproportionality signal is NICOTINE POLACRILEX (PRR 44.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Nicotine Polacrilex	615	44.9	45.6
Nicotine	327	21.7	21.9
Aprepitant	131	18.6	18.8
Fosaprepitant Dimeglumine	80	15.2	15.3
Dexamethasone Sodium Phosphate	43	11.0	11.0
Selinexor	31	9.3	9.3
Granisetron	33	8.2	8.2
Irinotecan Hydrochloride	36	7.3	7.3
Oral Semaglutide	199	7.2	7.2
Dimenhydrinate	29	7.1	7.1
Sunitinib Malate	101	6.7	6.7
Cenobamate	21	6.5	6.5
Granisetron Hydrochloride	26	6.5	6.5
Sorafenib	49	6.1	6.1
Cariprazine	22	6.1	6.1
Quinine	20	6.0	6.1
Fluorouracil	177	6.0	6.0
Fluorouracil Cream, 0.5%	174	6.0	6.0
Sennosides 8.6 Mg Tablets	48	6.0	6.0
Senna	48	5.9	5.9
Oxaliplatin	165	5.9	5.9
Chlorhexidine Gluconate	20	5.7	5.7
Pemetrexed Disodium	82	5.6	5.6
Capecitabine	194	5.6	5.6
Cisplatin	165	5.6	5.6
Senna Leaf	49	5.5	5.5
Dronabinol	17	5.5	5.5
Teduglutide	28	5.4	5.4
Calcium Gluconate	25	5.4	5.4
Ado-Trastuzumab Emtansine	17	5.2	5.2
Aripiprazole Oral	80	5.0	5.1
Aripiprazole Orally Disintegrating	80	5.0	5.1
Bupivacaine	18	5.0	5.0
Pemetrexed	40	4.8	4.8
Amlodipine Besylate And Benazepril Hydrochloride	17	4.8	4.8
Magnesium Oxide	76	4.7	4.7
Atropine	15	4.7	4.7
Dexamethasone 1.5 Mg	498	4.6	4.6
Dexamethasone	500	4.6	4.6
Sennosides	52	4.5	4.5
Leucovorin Calcium	33	4.5	4.5
Exenatide	88	4.4	4.4
Liraglutide	80	4.2	4.2
Nicotine Polacrilex Mini	24	4.1	4.1
Nicotine Polarilex	24	4.1	4.1
Ixazomib	45	4.1	4.1
Pramipexole	24	4.1	4.1
Iohexol	13	4.1	4.1
Metoclopramide Hydrochloride	118	4.0	4.0
Diphenoxylate Hydrochloride And Atropine Sulfate	21	4.0	4.0
Calcium, Magnesium, Potassium, And Sodium Oxybates	13	3.9	3.9
Aripiprazole	180	3.9	3.9
Metoclopramide	81	3.8	3.8
Atropine Sulfate	16	3.8	3.8
Alemtuzumab	28	3.8	3.8
Prochlorperazine	40	3.7	3.7
Trimethoprim	17	3.7	3.7
Ropinirole	22	3.7	3.7
Felodipine Extended-Release Tablets	16	3.6	3.6
Felodipine	16	3.6	3.6
Memantine	19	3.6	3.6
Memantine Hydrochloride	19	3.6	3.6
Regorafenib	16	3.6	3.6
Methylprednisolone Acetate	11	3.6	3.6
Rucaparib	12	3.5	3.5
Gemcitabine	53	3.5	3.5
Terazosin Hydrochloride	12	3.5	3.5
Panitumumab	21	3.5	3.5
Nitrofurantoin	22	3.5	3.5
Bortezomib	118	3.4	3.5
Mesna Injection	11	3.4	3.4
Nitrofurantoin (Monohydrate/Macrocrystals)	22	3.4	3.4
Mesna	11	3.4	3.4
Prochlorperazine Maleate	12	3.4	3.4
Lenalidomide	521	3.3	3.3
Itraconazole	15	3.3	3.3
Lactulose	49	3.3	3.3
Febuxostat Tablets 40 Mg	13	3.3	3.3
Febuxostat Tablets 80 Mg	13	3.3	3.3
Gemcitabine Hydrochloride	67	3.3	3.3
Bevacizumab	155	3.3	3.3
Donepezil Hydrochloride	46	3.3	3.3
Febuxostat	21	3.2	3.2
Durvalumab	25	3.2	3.2
Clarithromycin	42	3.2	3.2
Baclofen	102	3.1	3.1
Standardized Senna Concentrate	15	3.1	3.1
Exemestane	25	3.0	3.0
Methylprednisolone Sodium Succinate	54	3.0	3.0
Acetylcysteine	11	3.0	3.0
Glyburide	28	3.0	3.0
Cetuximab	36	3.0	3.0
Dalteparin Sodium	12	2.9	2.9
Human Insulin	14	2.9	2.9
Entecavir	13	2.9	2.9
Magnesium Hydroxide	15	2.9	2.9
Brivaracetam	10	2.9	2.9
Fesoterodine Fumarate	12	2.9	2.9
Carfilzomib	31	2.8	2.8
Docetaxel Anhydrous	73	2.8	2.8
Docetaxel	73	2.8	2.8
Sodium Chloride	85	2.8	2.8
Methocarbamol Tablets	18	2.8	2.8
Cholestyramine	13	2.8	2.8
Acyclovir	121	2.8	2.8
Oseltamivir Phosphate	26	2.8	2.8
Sodium Chloride Tablet	78	2.8	2.8
Sodium Chloride Tablets	78	2.8	2.8
Carboplatin	134	2.8	2.8
Ondansetron Hydrochloride	128	2.7	2.7
Nintedanib	33	2.7	2.7
Ondansetron	114	2.7	2.7
Ondansetron Tablets	114	2.7	2.7
Filgrastim	39	2.7	2.7
Asenapine Maleate	9	2.7	2.7
Erlotinib	10	2.7	2.7
Testosterone	24	2.7	2.7
Anastrozole Tablets	22	2.7	2.7
Extended Phenytoin Sodium	17	2.6	2.6
Methocarbamol	23	2.6	2.6
Fluconazole	70	2.6	2.6
Cabozantinib	48	2.6	2.6
Levofloxacin	60	2.6	2.6
Levofloxacin In 5% Dextrose	60	2.6	2.6
Dulaglutide	88	2.6	2.6
Gefitinib	9	2.6	2.6
Buspirone Hydrochloride	11	2.6	2.6
Bisacodyl	14	2.6	2.6
Ketoconazole	17	2.5	2.5
Pomalidomide	100	2.5	2.5
Loperamide Hydrochloride Oral	10	2.5	2.5
Famotidine	114	2.5	2.5
Metformin Hcl	53	2.5	2.5
Fluticasone Propionate Nasal	29	2.5	2.5
Hydrocortisone Sodium Succinate	9	2.5	2.5
Calcitriol Capsules 0.25 Mcg	19	2.5	2.5
Calcitriol Capsules 0.5 Mcg	19	2.5	2.5
Ketoconazole Foam	14	2.5	2.5
Amoxicillin	72	2.5	2.5
Niacin	11	2.5	2.5
Ketoconazole Cream, 2%	14	2.4	2.4
Calcitriol	19	2.4	2.4
Allopurinol	145	2.4	2.4
Cimetidine	9	2.4	2.4
Bisacodyl Suppositories	12	2.4	2.4
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	28	2.4	2.4
Pazopanib Hydrochloride	25	2.4	2.4
Axitinib	18	2.4	2.4
Biscodyl	12	2.4	2.4
Atezolizumab	35	2.3	2.3
Loperamide Hydrochloride	40	2.3	2.3
Paclitaxel	88	2.3	2.3
Indapamide	16	2.3	2.3
Zinc	22	2.3	2.3
Pantoprazole Sodium In 0.9% Sodium Chloride	55	2.3	2.3
Pantoprazole Sodium Injection	55	2.3	2.3
Zinc Chloride	22	2.3	2.3
Lenvatinib	29	2.3	2.3
Tamsulosin Hydrochloride	18	2.3	2.3
Finasteride	53	2.3	2.3
Erlotinib Hydrochloride	11	2.3	2.3
Bleomycin Sulfate	9	2.3	2.3
Blinatumomab	9	2.2	2.2
Voriconazole	26	2.2	2.2
Loperamide Hcl	11	2.2	2.2
Lidocaine Hydrochloride	51	2.2	2.2
Pertuzumab	23	2.2	2.2
Magnesium Sulfate Heptahydrate	11	2.2	2.2
Zinc Gluconate	22	2.2	2.2
Dextrose	11	2.2	2.2
Cytarabine	50	2.2	2.2
Olanzapine	89	2.2	2.2
Methadone Hydrochloride	9	2.2	2.2
Polyethylene Glycol	9	2.2	2.2
Micafungin Sodium	7	2.1	2.1
Doxycycline	56	2.1	2.1
Dextrose Monohydrate	11	2.1	2.1
Glipizide	50	2.1	2.1
Doxycycline Hyclate	55	2.1	2.1
Sertraline	95	2.1	2.1
Niraparib	18	2.1	2.1
Multivitamin	40	2.1	2.1
Docusate Sodium 100Mg	19	2.1	2.1
Sucralfate	19	2.1	2.1
Aspirin 325 Mg	392	2.0	2.0
Aspirin 81 Mg	392	2.0	2.0
Aspirin	411	2.0	2.0
Testosterone Cypionate	7	2.0	2.0
Magnesium Sulfate In Water For	10	2.0	2.0
Valacyclovir Hydrochloride	55	2.0	2.0
Lisinopril And Hydrochlorothiazide	8	2.0	2.0
Ursodiol	17	2.0	2.0
Loperamide Hydrochloride And Dimethicone	25	2.0	2.0
Amantadine	12	2.0	2.0
Chlorthalidone	9	2.0	2.0
Methadone	33	2.0	2.0
Magnesium Sulfate	10	2.0	2.0
Rotigotine	11	2.0	2.0
Midazolam	19	2.0	2.0
Doxazosin	21	1.9	1.9
Thyroid, Porcine	8	1.9	1.9
Melphalan	17	1.9	1.9
Buprenorphine Hydrochloride, Naloxone Hydrochloride	18	1.9	1.9
Trifluridine And Tipiracil	8	1.9	1.9
Pyrazinamide	7	1.9	1.9
Diazepam Oral Solution (Concentrate)	66	1.9	1.9
Diazepam Oral	66	1.9	1.9
Anti-Thymocyte Globulin (Rabbit)	6	1.9	1.9
Amlodipine Besylate	108	1.9	1.9
Ramipril	91	1.9	1.9
Voriconazole Injection	16	1.9	1.9
Paclitaxel (Aibumin-Bound)	60	1.9	1.9
Losartan	127	1.9	1.9
Enoxaparin Sodium	42	1.9	1.9
Clopidogrel Bisulfate	74	1.9	1.9
Benzonatate	12	1.9	1.9
Nifedipine	34	1.9	1.9
Doxazosin Mesylate	26	1.9	1.9
Lansoprazole	127	1.9	1.9
Amiodarone Hydrochloride	8	1.8	1.8
Diazepam	86	1.8	1.8
Etoposide	52	1.8	1.8
Aflibercept	22	1.8	1.8
Doxyclycline Hyclate	12	1.8	1.8
Enalapril	39	1.8	1.8
Loratadine Oral	34	1.8	1.8
Rivastigmine	13	1.8	1.8
Phenobarbital	10	1.8	1.8
Losartan Potassium	54	1.8	1.8
Vincristine Sulfate	20	1.8	1.8
Anastrozole	25	1.8	1.8
Insulin Human	27	1.8	1.8
Terbinafine Hydrochloride	6	1.7	1.7
Vismodegib	6	1.7	1.7
Bisoprolol Fumarate	91	1.7	1.7
Omeprazole	229	1.7	1.7
Omeprazole Magnesium	295	1.7	1.7
Umeclidinium	6	1.7	1.7
Empagliflozin	45	1.7	1.7
Ursosiol	13	1.7	1.7
Midazolam Hydrochloride	18	1.7	1.7
Valproic Acid	21	1.7	1.7
Vemurafenib	8	1.7	1.7
Darunavir	10	1.7	1.7
Rabeprazole Sodium	18	1.7	1.7
Tirzepatide	106	1.7	1.7
Linagliptin	12	1.7	1.7
Propofol	24	1.7	1.7
Trastuzumab	45	1.7	1.7
Pravastatin Sodium	13	1.7	1.7
Metoprolol Tartrate Injection	123	1.7	1.7
Ifosfamide	14	1.7	1.7
Valacyclovir	27	1.7	1.7
Haloperidol Lactate	16	1.7	1.7
Instalax Polyethylene Glycol 3350	8	1.7	1.7
Olanzapine Pamoate	26	1.6	1.6
Quinapril Hydrochloride	5	1.6	1.6
Esomeprazole Magnesium	147	1.6	1.6
Rimegepant Sulfate	8	1.6	1.6
Polyethylene Glycol 400	8	1.6	1.6
Daratumumab	25	1.6	1.6
Lovastatin	16	1.6	1.6
Insulin Aspart	41	1.6	1.6
Pembrolizumab	65	1.6	1.6
Polyethylene Glycol 3350	59	1.6	1.6
Haloperidol	15	1.6	1.6
Levetiracetam	82	1.6	1.6
Metoprolol	155	1.6	1.6
Metoprolol Tartrate	166	1.6	1.6
Tramadol Hydrochloride	23	1.6	1.6
Zonisamide	9	1.6	1.6
Raltegravir	10	1.6	1.6
Sevoflurane	5	1.6	1.6
Zoledronic Acid	24	1.5	1.5
Sitagliptin	43	1.5	1.5
Mirabegron	23	1.5	1.5
Lacosamide	22	1.5	1.5
Pitavastatin Calcium	6	1.5	1.5
Metformin Er 500 Mg	175	1.5	1.5
Metformin Er 750 Mg	175	1.5	1.5
Brentuximab Vedotin	6	1.5	1.5
Lapatinib	9	1.5	1.5
Budesonide, Glycopyrrolate, And Formoterol Fumarate	6	1.5	1.5
Lisinopril	174	1.5	1.5
Armodafinil	12	1.5	1.5
Nirmatrelvir And Ritonavir	30	1.4	1.4
Doxorubicin Hydrochloride	18	1.4	1.4
Crizotinib	7	1.4	1.4
Triamcinolone Acetonide	17	1.4	1.4
Loratadine	59	1.4	1.4
Levetiracetam In Sodium Chloride	42	1.4	1.4
Levetiracetam Oral	42	1.4	1.4
Levetiracetam Injection	42	1.4	1.4
Brexpiprazole	9	1.4	1.4
Nivolumab	52	1.4	1.4
Ritonavir 100 Mg	8	1.4	1.4
Ipilimumab	23	1.4	1.4
Pioglitazone	23	1.4	1.4
Tadalafil	53	1.4	1.4
Deferasirox	14	1.4	1.4
Dexlansoprazole	22	1.4	1.4
Bendamustine Hcl	8	1.3	1.3
Glimepiride	20	1.3	1.3
Mometasone Furoate And Formoterol Fumarate Dihydrate	8	1.3	1.3
Polatuzumab Vedotin	5	1.3	1.3
Insulin Degludec	12	1.3	1.3
Tafamidis	6	1.3	1.3
Relugolix	12	1.3	1.3
Dapagliflozin	16	1.3	1.3
Axicabtagene Ciloleucel	5	1.3	1.3
Dorzolamide Hydrochloride And Timolol Maleate	4	1.3	1.3
Ticagrelor	16	1.3	1.3
Bendamustine Hydrochloride	6	1.3	1.3
Levocetirizine Dihydrochloride	12	1.3	1.3
Inclisiran	4	1.3	1.3
Ibrutinib	40	1.3	1.3
Clobazam	12	1.3	1.3
Risperidone	65	1.3	1.3
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	4	1.3	1.3
Dabrafenib	10	1.2	1.2
Doxorubicin	42	1.2	1.2
Sodium Oxybate	31	1.2	1.2
Cannabidiol	11	1.2	1.2
Ocrelizumab	29	1.2	1.2
Pirfenidone	19	1.2	1.2
Carbidopa And Levodopa	22	1.2	1.2
Alpelisib	4	1.2	1.2
Pegfilgrastim	45	1.2	1.2
Trametinib	11	1.2	1.2
Linaclotide	12	1.2	1.2
Insulin Lispro	62	1.2	1.2
Sacubitril And Valsartan	52	1.2	1.2
Ravulizumab	6	1.1	1.1
Emtricitabine And Tenofovir Alafenamide	5	1.1	1.1
Morphine Sulfate	53	1.1	1.1
Imatinib Mesylate	12	1.1	1.1
Obinutuzumab	7	1.1	1.1
Dabigatran Etexilate Mesylate	30	1.1	1.1
Dabigatran Etexilate	32	1.1	1.1
Oxycodone Hydrochloride	89	1.1	1.1
Alteplase	6	1.0	1.0
Fam-Trastuzumab Deruxtecan-Nxki	4	1.0	1.0
Fingolimod Hcl	34	1.0	1.0
Ofatumumab	13	1.0	1.0
Suvorexant	5	1.0	1.0
Interferon Beta-1B	7	0.9	0.9
Patiromer	5	0.9	0.9
Venetoclax	22	0.9	0.9
Palbociclib	34	0.9	0.9
Varenicline Tartrate	28	0.9	0.9
Eltrombopag Olamine	8	0.9	0.9
Azacitidine	10	0.9	0.9
Bosutinib	3	0.9	0.9
Dimethyl Fumarate	41	0.9	0.9
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	6	0.9	0.9
Avapritinib	4	0.9	0.9
Agalsidase Beta	3	0.8	0.8
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	10	0.8	0.8
Ledipasvir And Sofosbuvir	6	0.8	0.8
Dalfampridine	22	0.8	0.8
Encorafenib	3	0.8	0.8
Teriparatide	34	0.8	0.8
Remdesivir	4	0.8	0.8
Pseudoephedrine Hydrochloride	3	0.8	0.8
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	12	0.7	0.7
Osimertinib	9	0.7	0.7
Glecaprevir And Pibrentasvir	3	0.7	0.7
Pseudoephedrine Hcl	3	0.7	0.7
Pimavanserin Tartrate	13	0.6	0.6
Natalizumab	40	0.6	0.6
Galcanezumab-Gnlm	6	0.5	0.5
Bimekizumab	4	0.5	0.5
Paliperidone Palmitate	6	0.5	0.5
Evolocumab	26	0.4	0.4
Voxelotor	3	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.