Reaction

Postoperative Wound Infection reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,652 reports · 389 co-occurring drugs

As of the last recalculation, Postoperative Wound Infection appears in 6,652 FAERS reports alongside 389 co-occurring drug terms. The strongest observed disproportionality signal is CHLORHEXIDINE GLUCONATE (PRR 12.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Chlorhexidine Gluconate	35	12.0	12.1
Bupivacaine	33	11.1	11.1
Diphenhydramine Hydrochloride Capsule, Liquid Filled	75	11.1	11.1
Human Immunoglobulin G	69	10.6	10.6
Infliximab-Dyyb	94	10.2	10.2
Nitrofurantoin (Monohydrate/Macrocrystals)	52	9.8	9.8
Nitrofurantoin	51	9.7	9.8
Octreotide Acetate	92	9.5	9.5
Indapamide	50	8.8	8.8
Acetaminophen And Codeine	34	8.8	8.8
Risedronate Sodium	76	7.7	7.7
Mycophenilic Acid	50	7.6	7.6
Amiodarone Hydrochloride	27	7.6	7.6
Cefazolin Sodium	28	7.3	7.3
Upadacitinib	174	6.8	6.8
Cefazolin	19	6.5	6.5
Leflunomide	212	6.5	6.5
Basiliximab	24	6.4	6.4
Cephalexin	41	6.0	6.0
Ustekinumab	190	6.0	6.0
Vedolizumab	157	5.8	5.8
Valganciclovir Hydrochloride Powder,	22	5.7	5.7
Mycophenolic Acid	57	5.6	5.6
Risankizumab-Rzaa	139	5.4	5.4
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	14	5.4	5.4
Temazepam	64	5.4	5.4
Clindamycin	48	5.3	5.3
Canagliflozin	50	5.3	5.3
Folic Acid	380	5.0	5.0
Adalimumab	991	5.0	5.0
Nystatin Ointment	41	4.9	4.9
Sodium Chloride Tablet	114	4.9	4.9
Sodium Chloride Tablets	114	4.9	4.9
Nystatin Cream	41	4.9	4.9
Sodium Chloride	121	4.9	4.9
Clindamycin Phosphate	51	4.8	4.8
Nystatin	41	4.7	4.7
Golimumab	127	4.7	4.7
Tacrolimus Ointment 0.1%	177	4.5	4.5
Cyclobenzaprine Hydrochloride	13	4.5	4.5
Infliximab	305	4.5	4.5
Tacrolimus Extended-Release Capsules	177	4.5	4.5
Valsartan Oral	76	4.4	4.4
Tacrolimus	215	4.4	4.4
Diphenhydramine	85	4.3	4.3
Methotrexate	535	4.2	4.2
Prednisolone	237	4.2	4.2
Prednisolone Oral	237	4.2	4.2
Prednisolone Oral Solution	237	4.2	4.2
Pantoprazole Sodium In 0.9% Sodium Chloride	82	4.2	4.2
Pantoprazole Sodium Injection	82	4.2	4.2
Adrenalinum	55	4.2	4.2
Valganciclovir	25	4.2	4.2
Valganciclovir Hydrochloride	25	4.2	4.2
Mycophenolate Mofetil	175	4.1	4.1
Methotrexate Sodium	595	4.1	4.1
Mycophenolate Mofetil Hydrochloride	175	4.1	4.1
Hyoscyamine Sulfate	12	4.1	4.1
Vortioxetine	22	4.1	4.1
Lactulose	49	4.0	4.0
Hydrocortisone Sodium Succinate	12	4.0	4.0
Calcium	183	3.9	3.9
Celecoxib	161	3.9	3.9
Prednisone	582	3.9	3.9
Diphenhydramine Hydrochloride	200	3.9	3.9
Ado-Trastuzumab Emtansine	10	3.7	3.7
Mesalamine	66	3.7	3.7
Torsemide	39	3.7	3.7
Cholestyramine	14	3.6	3.6
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	35	3.6	3.6
Oxybutynin Chloride	10	3.6	3.6
Methocarbamol Tablets	19	3.6	3.6
Valsartan	117	3.5	3.5
Methylprednisolone	152	3.5	3.5
Vancomycin Hydrochloride	73	3.5	3.5
Vancomycin	64	3.5	3.5
Canakinumab	12	3.5	3.5
Meclizine	18	3.5	3.5
Ciclesonide	15	3.5	3.5
Diclofenac Sodium 1%	39	3.4	3.4
Diclofenac Sodium Topical	39	3.4	3.4
Diclofenac Sodium Topical Gel, 1%	39	3.4	3.4
Lidicaine	53	3.4	3.4
Burn Relief	53	3.4	3.4
Buspirone Hydrochloride	12	3.4	3.4
Esomeprazole	67	3.4	3.4
Lidocaine Hydrochloride And Epinephrine	53	3.4	3.4
Daptomycin	10	3.4	3.4
Lidocaine, Menthol	53	3.4	3.4
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	33	3.3	3.3
Meropenem	34	3.3	3.3
Ciprofloxacin Hydrochloride And Hydrocortisone	22	3.3	3.3
Methocarbamol	24	3.3	3.3
Hydroxyzine	50	3.3	3.3
Mupirocin	14	3.3	3.3
Acetaminophen Tablet Extended Release	258	3.3	3.3
Pain Reliever	258	3.3	3.3
Acetaminophen 500Mg	258	3.2	3.3
Lidocaine Hydrochloride And Epinephrine Bitartrate	55	3.2	3.2
Lidocaine	60	3.2	3.2
Standardized Senna Concentrate	13	3.2	3.2
Niacin	12	3.2	3.2
Docusate Sodium - Sennosides	33	3.2	3.2
Promethazine Hydrochloride	19	3.2	3.2
Diphenoxylate Hydrochloride And Atropine Sulfate	14	3.2	3.2
Mupirocin Calcium	14	3.2	3.2
Patiromer	14	3.2	3.2
Enalapril	56	3.2	3.2
Tranexamic Acid	9	3.2	3.2
Metronidazole Topical	48	3.2	3.2
Azathioprine	88	3.2	3.2
Docusate Sodium 100Mg	24	3.1	3.2
Cyanocobalamin	33	3.1	3.1
Meloxicam	58	3.1	3.1
Pantoprazole	247	3.1	3.1
Hydroxychloroquine Sulfate	90	3.1	3.1
Diclofenac	85	3.1	3.1
Tofacitinib Citrate	13	3.1	3.1
Metronidazole	63	3.1	3.1
Hydroxyzine Hydrochloride	13	3.1	3.1
Hydroxyzine Hydrochloride Oral	13	3.1	3.1
Fondaparinux Sodium	8	3.1	3.1
Ramipril	121	3.1	3.1
Abatacept	135	3.1	3.1
Doxepin	10	3.1	3.1
Cyclobenzaprine	49	3.1	3.1
Dicyclomine Hydrochloride	14	3.1	3.1
Ganciclovir	10	3.1	3.1
Lidocaine 4%	53	3.1	3.1
Linezolid	29	3.1	3.1
Docusate Sodium	56	3.1	3.1
Naproxen	76	3.1	3.1
Insulin	54	3.0	3.0
Atenolol	128	3.0	3.0
Meclizine Hydrochloride	19	3.0	3.0
Adalimumab-Adaz	51	3.0	3.0
Metoprolol Succinate Er Tablets	60	3.0	3.0
Sulfasalazine	75	3.0	3.0
Everolimus Tablets	16	3.0	3.0
Epinephrine	62	3.0	3.0
Lidocaine Hydrochloride	57	3.0	3.0
Azelastine	17	3.0	3.0
Ganciclovir Sodium	10	3.0	3.0
Minocycline	11	3.0	3.0
Micafungin Sodium	8	3.0	3.0
Iron	62	2.9	2.9
Enalapril Maleate	23	2.9	2.9
Epoetin Alfa	11	2.9	2.9
Bisacodyl Suppositories	12	2.9	2.9
Bisacodyl	13	2.9	2.9
Pantoprazole Sodium	135	2.9	2.9
Tocilizumab	104	2.9	2.9
Biscodyl	12	2.9	2.9
Piperacillin Sodium And Tazobactam Sodium	18	2.9	2.9
Adalimumab-Fkjp	42	2.8	2.9
Niraparib	20	2.8	2.8
Azithromycin	36	2.8	2.8
Esomeprazole Magnesium Capsule, Delayed Release	13	2.8	2.8
Esomeprazole Magnesium Delayed Release Capsules	13	2.8	2.8
Trazodone Hydrochloride	14	2.8	2.8
Testosterone Cypionate	8	2.8	2.8
Acetaminophen	386	2.8	2.8
Esomeprazole Magnesium Dihydrate	13	2.8	2.8
Tolterodine Tartrate	8	2.8	2.8
Sirolimus	12	2.8	2.8
Rifampin	13	2.8	2.8
Adalimumab-Aaty	42	2.8	2.8
Hydroxychloroquine	66	2.8	2.8
Human Insulin	11	2.8	2.8
Cefepime Hydrochloride	14	2.7	2.7
Prochlorperazine Maleate	8	2.7	2.7
Ciprofloxacin	79	2.7	2.7
Azithromycin Monohydrate	36	2.7	2.7
Mercaptopurine	15	2.7	2.7
Baclofen	74	2.7	2.7
Piperacillin And Tazobactam	11	2.7	2.7
Cetirizine Hydrochloride Allergy	26	2.7	2.7
Cetirizine Hydrochloride Tablets	26	2.7	2.7
Vitamin C	78	2.7	2.7
Dalteparin Sodium	9	2.7	2.7
Oxycodone And Acetaminophen Tablets	10	2.6	2.6
Ciprofloxacin Hydrochloride	81	2.6	2.6
Leucovorin Calcium	16	2.6	2.6
Hydrochlorothiazide	120	2.6	2.6
Fluconazole	58	2.6	2.6
Piperacillin Sodium,Tazobactam Sodium	22	2.6	2.6
Tizanidine Hydrochloride	15	2.6	2.6
Losartan	143	2.6	2.6
Secukinumab	132	2.6	2.6
Ursosiol	16	2.6	2.6
Gentamicin Sulfate	13	2.6	2.6
Magnesium	67	2.6	2.6
Certolizumab Pegol	95	2.6	2.6
Ciprofolxacin	58	2.5	2.5
Ciprofloxacin Tablets	58	2.5	2.5
Ketoconazole Foam	12	2.5	2.5
Metoprolol Succinate	70	2.5	2.5
Amoxicillin And Clavulanate Potassium	22	2.5	2.5
Ketoconazole Cream, 2%	12	2.5	2.5
Clopidogrel Bisulfate	82	2.5	2.5
Meclizine Hcl 12.5Mg	11	2.5	2.5
Meclizine Hcl 25Mg	11	2.5	2.5
Meclizine Hcl 12.5 Mg	11	2.5	2.5
Meclizine Hcl 25 Mg	11	2.5	2.5
Sennosides	24	2.5	2.5
Calcitriol Capsules 0.25 Mcg	16	2.5	2.5
Calcitriol Capsules 0.5 Mcg	16	2.5	2.5
Gabapentin	283	2.5	2.5
Sucralfate	19	2.5	2.5
Calcitriol	16	2.5	2.5
Enoxaparin Sodium	45	2.5	2.5
Umeclidinium	7	2.4	2.4
Palivizumab	12	2.4	2.4
Ursodiol	17	2.4	2.4
Ferrous Sulfate	39	2.4	2.4
Dexlansoprazole	32	2.4	2.4
Bisoprolol Fumarate	103	2.4	2.4
Doxyclycline Hyclate	13	2.4	2.4
Ketoprofen	10	2.4	2.4
Glipizide	46	2.4	2.4
Fexofenadine Hcl	7	2.4	2.4
Venlafaxine	54	2.4	2.4
Fentanyl	74	2.4	2.4
Doxycycline	51	2.3	2.4
Loperamide Hydrochloride And Dimethicone	24	2.3	2.3
Dapsone	8	2.3	2.3
Vibegron	6	2.3	2.3
Ergocalciferol	280	2.3	2.3
Anti-Thymocyte Globulin (Rabbit)	6	2.3	2.3
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	117	2.3	2.3
Biotin	23	2.3	2.3
Aspirin 81 Mg	366	2.3	2.3
Aspirin 325 Mg	365	2.3	2.3
Fluticasone Propionate And Salmeterol Xinafoate	44	2.3	2.3
Diclofenac Sodium	109	2.3	2.3
Amlodipine Besylate	106	2.3	2.3
Doxycycline Hyclate	49	2.3	2.3
Fexofenadine	12	2.3	2.3
Atorvastatin Calcium	177	2.3	2.3
Instalax Polyethylene Glycol 3350	9	2.3	2.3
Daspone	7	2.3	2.3
Dapsone Gel, 5%	7	2.2	2.3
Amphotericin B	9	2.2	2.3
Aspirin	374	2.2	2.2
Amantadine	11	2.2	2.2
Famotidine	83	2.2	2.2
Polyethylene Glycol 400	9	2.2	2.2
Omeprazole	238	2.2	2.2
Loperamide Hcl	9	2.2	2.2
Loperamide Hydrochloride	31	2.2	2.2
Simvastatin	171	2.2	2.2
Guaifenesin	21	2.2	2.2
Regorafenib	8	2.2	2.2
Miconazole Nitrate	6	2.2	2.2
Erythropoietin	14	2.1	2.1
Metoprolol Tartrate Injection	128	2.1	2.1
Clobetasol Propionate Ointment Usp, 0.05%	7	2.1	2.1
Clobetasol Propionate	7	2.1	2.1
Naproxen Sodium	96	2.1	2.1
Tizanidine	16	2.1	2.1
Duloxetine Hydrochloride	124	2.1	2.1
Dolutegravir Sodium	6	2.1	2.1
Estradiol Gel 0.1%	30	2.1	2.1
Estradiol Transdermal	30	2.1	2.1
Memantine	9	2.1	2.1
Memantine Hydrochloride	9	2.1	2.1
Fish Oil	59	2.1	2.1
Loratadine Tablet	35	2.0	2.0
Ifosfamide	14	2.0	2.0
Clopidogrel	128	2.0	2.0
Omeprazole Magnesium	280	2.0	2.0
Omalizumab	54	2.0	2.0
Hydromorphone Hydrochloride	58	2.0	2.0
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	13	2.0	2.0
Naproxen Sodium, Pseudoephedrine Hydrochloride	13	2.0	2.0
Rituximab	132	2.0	2.0
Nebivolol	10	2.0	2.0
Cefepime	9	2.0	2.0
Interferon Beta-1A	120	2.0	2.0
Baricitinib	6	1.9	1.9
Metoprolol	155	1.9	1.9
Estradiol	53	1.9	1.9
Polatuzumab Vedotin	6	1.9	1.9
Bimekizumab	13	1.9	1.9
Losartan Potassium	48	1.9	1.9
Bupropion	27	1.9	1.9
Benzonatate	10	1.9	1.9
Anakinra	10	1.9	1.9
Asfotase Alfa	6	1.9	1.9
Tofacitinib	109	1.9	1.9
Teduglutide	8	1.9	1.9
Desvenlafaxine Succinate	16	1.9	1.9
Prasugrel Hydrochloride	6	1.8	1.8
Insulin Glulisine	6	1.8	1.8
Loperamide Hydrochloride Oral	6	1.8	1.8
Insulin Aspart	38	1.8	1.8
Nintedanib	18	1.8	1.8
Eculizumab	31	1.8	1.8
Sitagliptin	41	1.8	1.8
Paricalcitol	8	1.8	1.8
Cabozantinib	27	1.8	1.8
Linaclotide	15	1.8	1.8
Sildenafil Powder,	20	1.8	1.8
Sunitinib Malate	22	1.8	1.8
Loratadine	60	1.8	1.8
Eptinezumab-Jjmr	5	1.7	1.7
Ocrelizumab	34	1.7	1.7
Peginterferon Beta-1A	7	1.7	1.7
Everolimus	27	1.7	1.7
Etanercept	311	1.7	1.7
Oxycodone Hydrochloride And Acetaminophen	52	1.7	1.7
Sevelamer Carbonate	6	1.6	1.6
Armodafinil	11	1.6	1.6
Lenvatinib	17	1.6	1.6
Insulin Degludec	12	1.6	1.6
Panitumumab	8	1.6	1.6
Abemaciclib	10	1.6	1.6
Rivaroxaban	103	1.6	1.6
Oxycodone	91	1.5	1.5
Rotigotine	7	1.5	1.5
Polyethylene Glycol 3350	46	1.5	1.5
Budesonide, Glycopyrrolate, And Formoterol Fumarate	5	1.5	1.5
Oxycodone And Acetaminophen	11	1.5	1.5
Naltrexone Hydrochloride And Bupropion Hydrochloride	4	1.5	1.5
Irinotecan Hydrochloride	6	1.5	1.5
Fluorouracil	36	1.5	1.5
Calcium, Magnesium, Potassium, And Sodium Oxybates	4	1.5	1.5
Natalizumab	84	1.5	1.5
Macitentan	32	1.4	1.4
Teriparatide	51	1.4	1.4
Insulin Glargine	110	1.4	1.4
Fluorouracil Cream, 0.5%	34	1.4	1.4
Ravulizumab	6	1.4	1.4
Pertuzumab	12	1.4	1.4
Oral Semaglutide	32	1.4	1.4
Agalsidase Beta	4	1.4	1.4
Darbepoetin Alfa	23	1.3	1.3
Rocuronium Bromide	5	1.3	1.3
Insulin Lispro	58	1.3	1.3
Oxaliplatin	31	1.3	1.3
Dapagliflozin	13	1.3	1.3
Cisplatin	32	1.3	1.3
Trastuzumab	28	1.3	1.3
Bevacizumab	50	1.3	1.3
Docetaxel Anhydrous	27	1.3	1.3
Docetaxel	27	1.3	1.3
Benralizumab	8	1.3	1.3
Erlotinib Hydrochloride	5	1.3	1.3
Rimegepant Sulfate	5	1.2	1.2
Crizotinib	5	1.2	1.2
Dabrafenib	8	1.2	1.2
Temozolomide	8	1.2	1.2
Sodium Oxybate	25	1.2	1.2
Deferasirox	10	1.2	1.2
Nivolumab	36	1.2	1.2
Ipilimumab	16	1.2	1.2
Denosumab	73	1.1	1.1
Axitinib	7	1.1	1.1
Sarilumab	9	1.1	1.1
Guselkumab	12	1.0	1.0
Vemurafenib	4	1.0	1.0
Acetaminophen, Aspirin, And Caffeine	7	1.0	1.0
Romiplostim	5	1.0	1.0
Ixekizumab	12	1.0	1.0
Cortisone Acetate	4	1.0	1.0
Exenatide	17	1.0	1.0
Elexacaftor, Tezacaftor, And Ivacaftor	4	1.0	1.0
Belimumab	10	1.0	1.0
Abiraterone	4	0.9	0.9
Dimethyl Fumarate	35	0.9	0.9
Valbenazine	7	0.9	0.9
Methoxy Polyethylene Glycol-Epoetin Beta	3	0.9	0.9
Hydrocodone Bitartrate And Acetaminophen	15	0.8	0.8
Apalutamide	3	0.8	0.8
Dornase Alfa	5	0.8	0.8
Diroximel Fumarate	3	0.8	0.8
Droxidopa	5	0.7	0.7
Sacubitril And Valsartan	25	0.7	0.7
Relugolix	5	0.7	0.7
Pegfilgrastim	19	0.6	0.6
Etonogestrel	9	0.6	0.6
Minoxidil Foam 5% (Womens)	6	0.6	0.6
Tapentadol Hydrochloride	6	0.6	0.6
Esketamine Hydrochloride	3	0.5	0.5
Pomalidomide	17	0.5	0.5
Copper	6	0.4	0.4
Minoxidil	6	0.4	0.4
Evolocumab	18	0.3	0.3
Adapalene	3	0.1	0.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.