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Which drugs are most reported with Haemodynamic instability?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,399 reports · 404 co-occurring drugs

As of the last recalculation, Haemodynamic Instability appears in 7,399 FAERS reports alongside 404 co-occurring drug terms. The strongest observed disproportionality signal is NOREPINEPHRINE (PRR 49.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Norepinephrine	182	49.1	49.9
Norepinephrine Bitartrate	233	47.0	47.7
Sevoflurane	97	33.3	33.6
Propofol	342	27.6	27.8
Rocuronium Bromide	112	27.1	27.4
Midazolam Hydrochloride	185	19.8	19.9
Midazolam	167	19.0	19.2
Atropine	48	16.4	16.5
Piperacillin And Tazobactam	73	16.2	16.3
Cefazolin	47	14.6	14.6
Vancomycin	272	13.7	13.8
Atropine Sulfate	52	13.6	13.7
Meropenem	149	13.3	13.4
Vancomycin Hydrochloride	300	13.3	13.4
Gentamicin	61	13.2	13.3
Cefepime	66	13.1	13.1
Piperacillin Sodium,Tazobactam Sodium	121	13.0	13.1
Magnesium Sulfate In Water For	57	12.6	12.7
Cefazolin Sodium	53	12.5	12.5
Magnesium Sulfate Heptahydrate	57	12.4	12.4
Magnesium Sulfate	57	12.4	12.4
Cefepime Hydrochloride	70	12.3	12.4
Gentamicin Sulfate	68	12.2	12.3
Daptomycin	39	11.9	12.0
Bupivacaine	39	11.8	11.8
Piperacillin Sodium And Tazobactam Sodium	81	11.7	11.8
Heparin Sodium	56	11.5	11.6
Ceftriaxone	132	11.5	11.5
Phenobarbital	56	10.9	11.0
Basiliximab	45	10.8	10.9
Ceftriaxone Sodium	143	10.7	10.7
Adrenalinum	146	10.1	10.1
Ganciclovir	36	9.9	10.0
Tranexamic Acid	31	9.8	9.9
Captopril	33	9.7	9.7
Ganciclovir Sodium	36	9.6	9.6
Anti-Thymocyte Globulin (Rabbit)	27	9.4	9.5
Fondaparinux Sodium	27	9.4	9.4
Oxazepam	69	9.1	9.1
Derma Foam Excel Hand Sanitizer	24	8.5	8.5
Ethanol	24	8.4	8.5
Linezolid	86	8.2	8.2
Remdesivir	38	8.1	8.1
Micafungin Sodium	24	8.0	8.0
Calcium Gluconate	34	8.0	8.0
Sodium Bicarbonate	60	7.3	7.3
Sodium Bicarbonate Injection,	60	7.3	7.3
Amiodarone Hydrochloride	29	7.3	7.3
Voriconazole Injection	56	7.3	7.3
Methimazole	20	7.2	7.2
Cytarabine	150	7.1	7.2
Amikacin	43	7.1	7.1
Amphotericin B	31	7.0	7.0
Ampicillin	20	6.8	6.8
Ampicillin Sodium	20	6.8	6.8
Pegaspargase	29	6.7	6.7
Valproic Acid	74	6.7	6.7
Fentanyl	227	6.7	6.7
Phytonadione	20	6.6	6.7
Epinephrine	152	6.6	6.7
Metronidazole Topical	111	6.6	6.7
Lidicaine	113	6.6	6.6
Burn Relief	113	6.6	6.6
Vincristine Sulfate	68	6.6	6.6
Lidocaine Hydrochloride And Epinephrine	113	6.6	6.6
Metronidazole	146	6.5	6.6
Lidocaine, Menthol	113	6.5	6.5
Lidocaine Hydrochloride And Epinephrine Bitartrate	120	6.4	6.4
Epoprostenol	29	6.3	6.3
Voriconazole	66	6.2	6.2
Mycophenilic Acid	45	6.1	6.2
Lidocaine Hydrochloride	128	6.1	6.1
Lidocaine 4%	114	6.0	6.0
Mycophenolate Mofetil	278	5.9	6.0
Mycophenolate Mofetil Hydrochloride	278	5.9	5.9
Bupropion	92	5.9	5.9
Haloperidol Lactate	51	5.8	5.8
Haloperidol	50	5.8	5.8
Fluconazole	141	5.8	5.8
Eplerenone	26	5.7	5.7
Labetalol	27	5.7	5.7
Phenytoin	42	5.7	5.7
Lidocaine	115	5.6	5.6
Moxifloxacin	28	5.6	5.6
Linagliptin	36	5.6	5.6
Dexamethasone Sodium Phosphate	20	5.6	5.6
Valganciclovir Hydrochloride Powder,	24	5.6	5.6
Misoprostol	19	5.5	5.5
Alteplase	29	5.5	5.5
Tacrolimus Ointment 0.1%	234	5.4	5.4
Tacrolimus Extended-Release Capsules	234	5.4	5.4
Posaconazole Delayed-Release	21	5.4	5.4
Acetylcysteine	18	5.4	5.4
Dextrose	25	5.4	5.4
Sildenafil Powder,	67	5.3	5.3
Tacrolimus	287	5.3	5.3
Nebivolol	30	5.3	5.3
Enoxaparin Sodium	107	5.3	5.3
Dextrose Monohydrate	25	5.3	5.3
Melphalan	42	5.2	5.2
Melphalan Hydrochloride	46	5.2	5.2
Methylprednisolone	245	5.1	5.1
Anakinra	30	5.1	5.1
Valganciclovir	34	5.1	5.1
Valganciclovir Hydrochloride	34	5.1	5.1
Busulfan	28	5.0	5.0
Metformin Hydrochloride Tablet	100	5.0	5.0
0Xygen	86	5.0	5.0
Oxygen	86	5.0	5.0
Colchicine	46	4.9	4.9
Fluoxetine	115	4.9	4.9
Metformin Hydrochloride Tablets	99	4.9	4.9
Metformin Hydrochloride Extended-Release Tablets	99	4.9	4.9
Etoposide	126	4.9	4.9
Metformin Hydrochloride	101	4.9	4.9
Clopidogrel Bisulfate	173	4.8	4.9
Pyrazinamide	16	4.8	4.8
Telmisartan	30	4.7	4.7
Amlodipine	432	4.7	4.7
Mycophenolic Acid	53	4.7	4.7
Cefuroxime	19	4.7	4.7
Clindamycin	46	4.6	4.6
Insulin	89	4.5	4.5
Isoniazid	26	4.5	4.5
Levofloxacin	94	4.4	4.4
Levofloxacin In 5% Dextrose	94	4.4	4.4
Apixaban	104	4.4	4.4
Clindamycin Phosphate	52	4.4	4.4
Posaconazole	25	4.3	4.3
Sildenafil	87	4.3	4.3
Fludarabine Phosphate	59	4.2	4.3
Oseltamivir	12	4.2	4.2
Moxifloxacin Hydrochloride	30	4.2	4.2
Escitslopram	85	4.1	4.2
Diazepam Oral Solution (Concentrate)	128	4.1	4.1
Diazepam Oral	128	4.1	4.1
Lamotirigine	102	4.0	4.1
Lamotrigine Extended-Release	102	4.0	4.1
Lamotrigine Chewable Dispersible	102	4.0	4.1
Methylprednisolone Sodium Succinate	66	4.0	4.0
Alcohol	55	4.0	4.0
Levetiracetam In Sodium Chloride	109	4.0	4.0
Levetiracetam Oral	109	4.0	4.0
Levetiracetam Injection	109	4.0	4.0
Escitalopram Oxalate	102	4.0	4.0
Ciprofolxacin	100	4.0	4.0
Ciprofloxacin Tablets	100	4.0	4.0
Dabigatran Etexilate	108	4.0	4.0
Selexipag	36	3.9	3.9
Venlafaxine	99	3.9	3.9
Digoxin	98	3.9	3.9
Propranolol Hydrochloride	97	3.8	3.8
Metformin	460	3.8	3.8
Fentanyl Citrate	24	3.8	3.8
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	11	3.8	3.8
Anti-Itch	88	3.7	3.7
Anti-Pruritic	88	3.7	3.7
Antipruritic (Anti-Itch)	88	3.7	3.7
Cool Relief Gel With Aloe	88	3.7	3.7
Drs. Hydrocortisone	88	3.7	3.7
Hydrocortisone Continuous Spray	88	3.7	3.7
Hydrocortisone Spray	88	3.7	3.7
Anti-Itch Cream	88	3.7	3.7
Hydrocortisone Lotion	88	3.7	3.7
Hydrocortisone Cream 1%	88	3.7	3.7
Hydrocortisone Cream 1/2%	88	3.7	3.7
Hydrocortisone 1%	88	3.7	3.7
Hydrocortisone Cream	88	3.7	3.7
Acetaminophen Tablet Extended Release	324	3.7	3.7
Pain Reliever	324	3.7	3.7
Acetaminophen 500Mg	324	3.7	3.7
Morphine	96	3.7	3.7
Thiotepa	12	3.5	3.5
Bosentan	63	3.5	3.5
Metformin Er 500 Mg	362	3.5	3.5
Metformin Er 750 Mg	362	3.5	3.5
Loperamide Hcl	16	3.5	3.5
Diazepam	149	3.5	3.5
Hydrocortisone Acetate	89	3.5	3.5
Lithium	31	3.5	3.5
Lithium Bromatum	31	3.5	3.5
Clarithromycin	42	3.5	3.5
Axicabtagene Ciloleucel	12	3.4	3.4
Lacosamide	45	3.4	3.4
Mesna Injection	10	3.4	3.4
Ciprofloxacin Hydrochloride	116	3.4	3.4
Dabigatran Etexilate Mesylate	86	3.4	3.4
Mesna	10	3.3	3.3
Fluoxetine Hydrochloride	149	3.3	3.3
Torsemide	39	3.3	3.3
Lithium Carbonate	20	3.3	3.3
Ciprofloxacin	107	3.3	3.3
Nifedipine	55	3.3	3.3
Metolazone	13	3.3	3.3
Granisetron Hydrochloride	12	3.2	3.2
Nystatin Ointment	30	3.2	3.2
Nystatin Cream	30	3.2	3.2
Granisetron	12	3.2	3.2
Aripiprazole Oral	47	3.2	3.2
Aripiprazole Orally Disintegrating	47	3.2	3.2
Dalteparin Sodium	12	3.2	3.2
Ticagrelor	36	3.2	3.2
Daspone	11	3.2	3.2
Dapsone Gel, 5%	11	3.2	3.2
Ethyl Alcohol	30	3.1	3.1
Spironolactone	153	3.1	3.1
Nystatin	30	3.1	3.1
Azithromycin	44	3.1	3.1
Candesartan	39	3.1	3.1
Enalapril Maleate	27	3.1	3.1
Furosemide	420	3.1	3.1
Hydrocortisone	96	3.1	3.1
Tobramycin Solution	13	3.0	3.1
Loperamide Hydrochloride Oral	11	3.0	3.0
Cyclophosphamide Injection, Solution	187	3.0	3.0
Cyclophosphamide	187	3.0	3.0
Cyclophosphamide For Injection	187	3.0	3.0
Bisoprolol Fumarate	144	3.0	3.0
Quetiapine	202	3.0	3.0
Azithromycin Monohydrate	44	3.0	3.0
Tobramycin Sulfate	13	3.0	3.0
Risperidone	138	3.0	3.0
Sevelamer Carbonate	12	2.9	2.9
Isopropyl Alcohol	35	2.9	2.9
Clopidogrel	202	2.9	2.9
Glyburide	25	2.9	2.9
Dapsone	11	2.9	2.9
Cyclosporine	113	2.9	2.9
Polatuzumab Vedotin	10	2.9	2.9
Dexamethasone 1.5 Mg	292	2.9	2.9
Valproate Sodium	21	2.9	2.9
Metformin Hcl	56	2.9	2.9
Methocarbamol Tablets	17	2.9	2.9
Dexamethasone	292	2.8	2.8
Esomeprazole	62	2.8	2.8
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	10	2.8	2.8
Azacitidine For	18	2.8	2.8
Olanzapine	105	2.8	2.8
Macitentan	67	2.7	2.7
Diltiazem Hydrochloride Extended-Release Tablets	11	2.7	2.7
Insulin Glargine-Yfgn	21	2.7	2.7
Rifampin	14	2.7	2.7
Everolimus Tablets	16	2.7	2.7
Doxorubicin Hydrochloride	31	2.7	2.7
Doxorubicin	84	2.7	2.7
Clobazam	23	2.7	2.7
Lamotrigine	123	2.7	2.7
Citalopram Hydrobromide	100	2.6	2.6
Enalapril	52	2.6	2.6
Naproxen	73	2.6	2.6
Metoroprolol Tartrate	61	2.6	2.6
Polyethylene Glycol	10	2.6	2.6
Levetiracetam	122	2.6	2.6
Aprepitant	17	2.6	2.6
Amoxicillin	70	2.6	2.6
Ketoprofen	12	2.6	2.6
Baclofen	78	2.6	2.6
Imatinib	16	2.6	2.6
Erythromycin	17	2.6	2.6
Filgrastim	34	2.5	2.6
Sotalol Hydrochloride	15	2.5	2.5
Diphenhydramine Hcl	10	2.5	2.5
Esomeprazole Magnesium Capsule, Delayed Release	13	2.5	2.5
Esomeprazole Magnesium Delayed Release Capsules	13	2.5	2.5
Sildenafil Citrate	113	2.5	2.5
Esomeprazole Magnesium Dihydrate	13	2.5	2.5
Nebivolol Hydrochloride	30	2.5	2.5
Rifampicin	9	2.5	2.5
Ifosfamide	19	2.5	2.5
Amoxicillin And Clavulanate Potassium	24	2.5	2.5
Prednisolone	154	2.4	2.4
Prednisolone Oral	154	2.4	2.4
Prednisolone Oral Solution	154	2.4	2.4
Ranolazine	9	2.4	2.4
Lorazepam	152	2.4	2.4
Treprostinil	106	2.4	2.4
Bisacodyl Suppositories	11	2.4	2.4
Metoprolol	212	2.4	2.4
Venlafaxine Hydrochloride	111	2.4	2.4
Biscodyl	11	2.4	2.4
Clonidine	43	2.4	2.4
Methocarbamol	19	2.4	2.4
Ramipril	102	2.3	2.3
Riociguat	27	2.3	2.3
Bupropion Hydrochloride	81	2.3	2.3
Potassium Chloride, Dextrose Monohydrate	76	2.3	2.3
Potassium Chloride Oral	76	2.3	2.3
Potassium Chloride Extended-Release	76	2.3	2.3
Carbamazepine	55	2.3	2.3
Doxazosin	23	2.3	2.3
Cisplatin	64	2.3	2.3
Metoprolol Tartrate	221	2.3	2.3
Abacavir Sulfate	8	2.3	2.3
Metoprolol Tartrate Injection	153	2.3	2.3
Oxaliplatin	60	2.3	2.3
Lopinavir And Ritonavir	11	2.3	2.3
Sennosides 8.6 Mg Tablets	17	2.3	2.3
Senna	17	2.3	2.3
Azithromycin Dihydrate	47	2.3	2.3
Ibuprofen Capsule	158	2.3	2.3
Ibuprofen Tablet, Film Coated	158	2.3	2.3
Ibupfrofen	158	2.3	2.3
Ibuprofen Tablets Usp, 200Mg	158	2.3	2.3
Ibuprofen Oral	158	2.3	2.3
Ibuprofen Capsules 200 Mg	158	2.3	2.3
Ibuprofen 200 Mg	158	2.3	2.3
Ibuprofen 200Mg	158	2.3	2.3
Warfarin	100	2.2	2.2
Felodipine Extended-Release Tablets	9	2.2	2.2
Felodipine	9	2.2	2.2
Terazosin Hydrochloride	7	2.2	2.2
Leucovorin Calcium	15	2.2	2.2
Acetaminophen	342	2.2	2.2
Theophylline	9	2.2	2.2
Ropinirole	12	2.2	2.2
Quetiapine Fumarate	23	2.2	2.2
Chlorthalidone	9	2.2	2.2
Sennosides	23	2.2	2.2
Escitalopram	107	2.2	2.2
Metoclopramide	42	2.2	2.2
Atenolol	101	2.1	2.1
Citalopram	103	2.1	2.1
Valsartan Oral	41	2.1	2.1
Warfarin Sodium	35	2.1	2.1
Azacitidine	22	2.1	2.1
Dutasteride	6	2.1	2.1
Senna Leaf	17	2.1	2.1
Iron Sucrose	7	2.1	2.1
Memantine	10	2.1	2.1
Memantine Hydrochloride	10	2.1	2.1
Amphetamine	6	2.0	2.0
Sodium Chloride	57	2.0	2.0
Iohexol	6	2.0	2.0
Sodium Chloride Tablet	53	2.0	2.0
Sodium Chloride Tablets	53	2.0	2.0
Hydroxyurea	15	2.0	2.0
Methadone	30	2.0	2.0
Metoclopramide Hydrochloride	54	2.0	2.0
Dapagliflozin	22	2.0	2.0
Pemetrexed	15	2.0	2.0
Duloxetine	48	1.9	1.9
Prasugrel Hydrochloride	7	1.9	1.9
Tolvaptan	10	1.9	1.9
Aspirin 325 Mg	344	1.9	1.9
Aspirin 81 Mg	344	1.9	1.9
Rituximab	143	1.9	1.9
Alprazolam	139	1.9	1.9
Allopurinol	104	1.9	1.9
Aspirin	345	1.8	1.8
Oseltamivir Phosphate	16	1.8	1.8
Topiramate	60	1.8	1.8
Doxazosin Mesylate	23	1.8	1.8
Ondansetron	69	1.8	1.8
Ondansetron Tablets	69	1.8	1.8
Amlodipine Besylate And Valsartan	7	1.8	1.8
Acyclovir	71	1.8	1.8
Irinotecan Hydrochloride	8	1.8	1.8
Atovaquone	5	1.7	1.7
Tramadol Hydrochloride	23	1.7	1.7
Tadalafil	61	1.7	1.7
Insulin Degludec	14	1.7	1.7
Bicalutamide	9	1.7	1.7
Carvedilol	79	1.7	1.7
Oxcarbazepine	19	1.6	1.6
Levodopa	7	1.6	1.6
Pemetrexed Disodium	22	1.6	1.6
Eculizumab	31	1.6	1.6
Ziprasidone	10	1.6	1.6
Methadone Hydrochloride	6	1.6	1.6
Tobramycin	13	1.5	1.5
Clozapine	67	1.5	1.5
Gemcitabine	21	1.5	1.5
Temozolomide	11	1.5	1.5
Baricitinib	5	1.5	1.5
Rivaroxaban	107	1.5	1.5
Bortezomib	46	1.4	1.4
Gemcitabine Hydrochloride	27	1.4	1.4
Daratumumab	20	1.4	1.4
Capecitabine	45	1.4	1.4
Brentuximab Vedotin	5	1.4	1.4
Atazanavir	7	1.4	1.4
Vigabatrin	7	1.4	1.4
Empagliflozin	31	1.3	1.3
Bendamustine Hcl	7	1.3	1.3
Rasagiline Mesylate	5	1.3	1.3
Docetaxel Anhydrous	30	1.3	1.3
Docetaxel	30	1.3	1.3
Carboplatin	56	1.2	1.2
Paliperidone	10	1.2	1.2
Paricalcitol	6	1.2	1.2
Fluorouracil Cream, 0.5%	32	1.2	1.2
Paclitaxel (Aibumin-Bound)	34	1.2	1.2
Dronedarone	4	1.1	1.1
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	7	1.1	1.1
Blinatumomab	4	1.1	1.1
Paclitaxel	36	1.0	1.0
Sofosbuvir	7	1.0	1.0
Ambrisentan	44	1.0	1.0
Abemaciclib	6	0.8	0.8
Sarilumab	7	0.7	0.7
Durvalumab	5	0.7	0.7
Paliperidone Palmitate	7	0.6	0.6
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	6	0.5	0.5
Cinacalcet Hydrochloride	5	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.