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Which drugs are most reported with Lower gastrointestinal haemorrhage?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,325 reports · 405 co-occurring drugs

As of the last recalculation, Lower Gastrointestinal Haemorrhage appears in 7,325 FAERS reports alongside 405 co-occurring drug terms. The strongest observed disproportionality signal is DABIGATRAN ETEXILATE MESYLATE (PRR 52.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Dabigatran Etexilate Mesylate	1,140	52.6	53.5
Dabigatran Etexilate	1,179	51.2	52.0
Rivaroxaban	2,378	47.6	48.1
Dronedarone	59	16.6	16.6
Digoxin	283	11.6	11.7
Apixaban	239	10.5	10.5
Clopidogrel Bisulfate	358	10.4	10.4
Clopidogrel	656	10.2	10.3
Diltiazem Hydrochloride	122	10.2	10.2
Warfarin Sodium	160	10.0	10.0
Sotalol Hydrochloride	57	9.8	9.8
Aspirin	1,457	9.4	9.4
Polyethylene Glycol	35	9.2	9.3
Aspirin 325 Mg	1,273	8.3	8.4
Aspirin 81 Mg	1,273	8.3	8.4
Prasugrel Hydrochloride	29	8.1	8.2
Metolazone	32	8.1	8.1
Terazosin Hydrochloride	25	8.0	8.0
Nitroglycerin	148	8.0	8.0
Torsemide	90	7.8	7.8
Warfarin	326	7.6	7.6
Docusate Sodium - Sennosides	81	7.2	7.2
Febuxostat Tablets 40 Mg	25	7.0	7.0
Febuxostat Tablets 80 Mg	25	7.0	7.0
Potassium Chloride	267	6.9	6.9
Heparin Sodium	33	6.8	6.9
Ferrous Sulfate	118	6.8	6.8
Febuxostat	39	6.6	6.7
Amiodarone Hydrochloride	26	6.6	6.6
Carvedilol	303	6.6	6.6
Furosemide	837	6.6	6.6
Bumetanide	58	6.3	6.3
Ticagrelor	68	6.1	6.1
Isosorbide Mononitrate	44	6.1	6.1
Potassium Chloride, Dextrose Monohydrate	190	6.0	6.0
Potassium Chloride Oral	190	6.0	6.0
Potassium Chloride Extended-Release	190	6.0	6.0
Dalteparin Sodium	21	5.7	5.7
Metoprolol Tartrate	503	5.5	5.5
Donepezil Hydrochloride	69	5.4	5.4
Docusate Sodium	108	5.4	5.4
Multivitamin	93	5.3	5.3
Enoxaparin Sodium	106	5.3	5.3
Magnesium Oxide	77	5.3	5.3
Ezetimibe And Simvastatin	28	5.3	5.3
Metoprolol	433	5.1	5.1
Leucovorin Calcium	34	5.1	5.1
Metoroprolol Tartrate	116	5.1	5.1
Metoprolol Tartrate Injection	321	5.0	5.0
Isosorbide Dinitrate	34	5.0	5.0
Lovastatin	44	4.9	4.9
Metoprolol Succinate	145	4.8	4.8
Simvastatin	402	4.8	4.8
Enalapril Maleate	41	4.7	4.7
Meclizine Hcl 12.5Mg	22	4.6	4.6
Meclizine Hcl 25Mg	22	4.6	4.6
Meclizine Hcl 12.5 Mg	22	4.6	4.6
Meclizine Hcl 25 Mg	22	4.6	4.6
Spironolactone	216	4.5	4.5
Enalapril	85	4.4	4.4
Thiamine Hydrochloride	19	4.3	4.4
Glipizide	92	4.3	4.3
Amlodipine Besylate And Benazepril Hydrochloride	14	4.3	4.3
Lisinopril	432	4.2	4.2
Doxazosin	41	4.2	4.2
Regorafenib	17	4.2	4.2
Standardized Senna Concentrate	18	4.1	4.1
Niacin	16	3.9	3.9
Doxazosin Mesylate	49	3.9	3.9
Fondaparinux Sodium	11	3.9	3.9
Bisoprolol Fumarate	181	3.9	3.9
Dutasteride	11	3.8	3.9
Meclizine	22	3.8	3.8
Metoprolol Succinate Er Tablets	83	3.8	3.8
Magnesium Hydroxide	18	3.8	3.8
Dofetilide	14	3.8	3.8
Pantoprazole Sodium	194	3.8	3.8
Meclizine Hydrochloride	26	3.8	3.8
Gemfibrozil	20	3.8	3.8
Dimenhydrinate	14	3.7	3.7
Pantoprazole	319	3.7	3.7
Sucralfate	31	3.7	3.7
Finasteride	77	3.7	3.7
Glyburide	31	3.7	3.7
Insulin Glargine-Yfgn	28	3.6	3.7
Sucralfate Oral	18	3.6	3.6
Candesartan	45	3.6	3.6
Sucralfate Oral Suspension	18	3.6	3.6
Mycophenilic Acid	26	3.6	3.6
Olmesartan Medoxomil	45	3.6	3.6
Ascorbic Acid	29	3.6	3.6
Psyllium Husk	12	3.5	3.5
Indomethacin	16	3.4	3.4
Albuterol	143	3.4	3.4
Allopurinol	184	3.4	3.4
Fluticasone Propionate And Salmeterol Xinafoate	71	3.4	3.4
Epoetin Alfa	14	3.4	3.4
Docusate Sodium 100Mg	28	3.3	3.3
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	24	3.3	3.3
Naproxen Sodium, Pseudoephedrine Hydrochloride	24	3.3	3.3
Pantoprazole Sodium In 0.9% Sodium Chloride	71	3.3	3.3
Pantoprazole Sodium Injection	71	3.3	3.3
Anti-Itch	76	3.2	3.2
Anti-Pruritic	76	3.2	3.2
Antipruritic (Anti-Itch)	76	3.2	3.2
Cool Relief Gel With Aloe	76	3.2	3.2
Drs. Hydrocortisone	76	3.2	3.2
Hydrocortisone Continuous Spray	76	3.2	3.2
Hydrocortisone Spray	76	3.2	3.2
Quinapril Hydrochloride	9	3.2	3.2
Anti-Itch Cream	76	3.2	3.2
Hydrocortisone Lotion	76	3.2	3.2
Sennosides	34	3.2	3.2
Hydrocortisone Cream 1%	76	3.2	3.2
Hydrocortisone Cream 1/2%	76	3.2	3.2
Hydrocortisone 1%	76	3.2	3.2
Hydrocortisone Cream	76	3.2	3.2
Sevelamer Carbonate	13	3.2	3.2
Chlorthalidone	13	3.2	3.2
Sodium Bicarbonate	26	3.2	3.2
Sodium Bicarbonate Injection,	26	3.2	3.2
Azacitidine	33	3.2	3.2
Atorvastatin Calcium	268	3.2	3.2
Hydrocortisone Acetate	80	3.2	3.2
Valsartan And Hydrochlorothiazide	15	3.1	3.1
Azacitidine For	20	3.1	3.1
Cyanocobalamin	36	3.1	3.1
Meropenem	35	3.1	3.1
Oxycodone And Acetaminophen Tablets	13	3.1	3.1
Primidone	11	3.1	3.1
Cholestyramine	13	3.1	3.1
Tofacitinib Citrate	14	3.0	3.0
Ipratropium Bromide	38	3.0	3.0
Micafungin Sodium	9	3.0	3.0
Glimepiride	41	3.0	3.0
Nintedanib	33	3.0	3.0
Norepinephrine Bitartrate	15	3.0	3.0
Captopril	10	3.0	3.0
Diclofenac Sodium 1%	37	3.0	3.0
Diclofenac Sodium Topical	37	3.0	3.0
Cytarabine	62	2.9	3.0
Diclofenac Sodium Topical Gel, 1%	37	2.9	2.9
Losartan Potassium And Hydrochlorothiazide	12	2.9	2.9
Norepinephrine	11	2.9	2.9
Oxybutynin Chloride	9	2.9	2.9
Tiotropium Bromide	138	2.9	2.9
Lisinopril And Hydrochlorothiazide Tablets	8	2.9	2.9
Encorafenib	10	2.9	2.9
Iron	67	2.9	2.9
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	159	2.9	2.9
Ezetimibe	75	2.9	2.9
Indapamide	18	2.9	2.9
Bisacodyl Suppositories	13	2.9	2.9
Posaconazole Delayed-Release	11	2.8	2.9
Biscodyl	13	2.8	2.8
Bisacodyl	14	2.8	2.8
Nystatin Ointment	26	2.8	2.8
Oxybutynin	29	2.8	2.8
Omeprazole Magnesium	427	2.8	2.8
Nystatin Cream	26	2.8	2.8
Sitagliptin	71	2.8	2.8
Valsartan	103	2.8	2.8
Vitamin E	31	2.8	2.8
Guaifenesin	30	2.8	2.8
Mycophenolic Acid	31	2.8	2.8
Piperacillin Sodium And Tazobactam Sodium	19	2.8	2.8
Atenolol	127	2.7	2.7
Pravastatin Sodium	19	2.7	2.7
Clonidine	49	2.7	2.7
Amphotericin B	12	2.7	2.7
Fish Oil	86	2.7	2.7
Losartan	165	2.7	2.7
Abiraterone	13	2.7	2.7
Acetylcysteine	9	2.7	2.7
Nystatin	26	2.7	2.7
Lubiprostone	9	2.7	2.7
Ibuprofen And Diphenhydramine Citrate	22	2.7	2.7
Diclofenac	81	2.7	2.7
Phytonadione	8	2.7	2.7
Omeprazole	316	2.7	2.7
Loperamide Hydrochloride And Dimethicone	30	2.7	2.7
Eplerenone	12	2.7	2.7
Hydrocortisone	83	2.7	2.7
Fenofibrate	33	2.7	2.7
Amlodipine Besylate	133	2.6	2.6
Ketoprofen	12	2.6	2.6
Ropinirole	14	2.6	2.6
Zolpidem Tartrate	122	2.6	2.6
Rosuvastatin	182	2.6	2.6
Ibuprofen 200 Mg	177	2.6	2.6
Bevacizumab	110	2.5	2.5
Ibuprofen Capsule	176	2.5	2.5
Ibuprofen Tablet, Film Coated	176	2.5	2.5
Ibupfrofen	176	2.5	2.5
Ibuprofen Tablets Usp, 200Mg	176	2.5	2.5
Ibuprofen Oral	176	2.5	2.5
Ibuprofen Capsules 200 Mg	176	2.5	2.5
Ibuprofen 200Mg	176	2.5	2.5
Tolterodine Tartrate	8	2.5	2.5
Sertraline	103	2.5	2.5
Human Insulin	11	2.5	2.5
Lisinopril And Hydrochlorothiazide	9	2.5	2.5
Pitavastatin Calcium	9	2.5	2.5
Oseltamivir	7	2.5	2.5
Diltiazem Hydrochloride Extended-Release Tablets	10	2.5	2.5
Felodipine Extended-Release Tablets	10	2.5	2.5
Felodipine	10	2.5	2.5
Sorafenib	18	2.5	2.5
Dasatinib	32	2.5	2.5
Ibuprofen	230	2.5	2.5
Sennosides 8.6 Mg Tablets	18	2.4	2.4
Amlodipine	227	2.4	2.4
Senna	18	2.4	2.4
Polyethylene Glycol 3350	81	2.4	2.4
Loperamide Hydrochloride	38	2.4	2.4
Temazepam	32	2.4	2.4
Levothyroxine Sodium	261	2.4	2.4
Fluticasone Propionate And Salmeterol	35	2.4	2.4
Levofloxacin	50	2.4	2.4
Levofloxacin In 5% Dextrose	50	2.4	2.4
Valsartan Oral	45	2.4	2.4
Piperacillin Sodium,Tazobactam Sodium	22	2.4	2.4
Lorazepam	147	2.4	2.4
Busulfan	13	2.4	2.4
Labetalol	11	2.3	2.3
Sildenafil Powder,	29	2.3	2.3
Lactulose	31	2.3	2.3
Timolol Maleate	8	2.3	2.3
Memantine	11	2.3	2.3
Memantine Hydrochloride	11	2.3	2.3
Levothyroxine Sodium Anhydrous	80	2.3	2.3
Metformin Er 500 Mg	237	2.3	2.3
Metformin Er 750 Mg	237	2.3	2.3
Metronidazole	51	2.3	2.3
Posaconazole	13	2.3	2.3
Budesonide And Formoterol Fumarate Dihydrate	77	2.3	2.3
Latanoprost	40	2.3	2.3
Famotidine	93	2.3	2.3
Rivastigmine	15	2.3	2.3
0Xygen	39	2.3	2.3
Oxygen	39	2.3	2.3
Acetaminophen	346	2.3	2.3
Ipilimumab	34	2.2	2.2
Losartan Potassium	62	2.2	2.2
Magnesium Sulfate In Water For	10	2.2	2.2
Senna Leaf	18	2.2	2.2
Paricalcitol	11	2.2	2.2
Clobetasol Propionate Ointment Usp, 0.05%	8	2.2	2.2
Fluorouracil Cream, 0.5%	59	2.2	2.2
Clobetasol Propionate	8	2.2	2.2
Diclofenac Sodium	115	2.2	2.2
Magnesium Sulfate Heptahydrate	10	2.2	2.2
Magnesium Sulfate	10	2.2	2.2
Fluorouracil	59	2.2	2.2
Methimazole	6	2.2	2.2
Dextrose	10	2.2	2.2
Insulin Aspart	50	2.2	2.2
Fexofenadine Hcl	7	2.2	2.2
Tolvaptan	11	2.2	2.2
Hydrochlorothiazide	109	2.1	2.2
Alendronate Sodium Tablet	14	2.1	2.1
Insulin	42	2.1	2.1
Oxycodone Hydrochloride And Acetaminophen	74	2.1	2.1
Dextrose Monohydrate	10	2.1	2.1
Atezolizumab	29	2.1	2.1
Dronabinol	6	2.1	2.1
Cefepime Hydrochloride	12	2.1	2.1
Timolol	9	2.1	2.1
Nifedipine	35	2.1	2.1
Sitagliptin And Metformin Hydrochloride	16	2.1	2.1
Pioglitazone	32	2.1	2.1
Iron Sucrose	7	2.1	2.1
Nicotine Polacrilex Mini	11	2.1	2.1
Nicotine Polarilex	11	2.1	2.1
Albuterol Sulfate	214	2.1	2.1
Budesonide	43	2.1	2.1
Metoclopramide	40	2.1	2.1
Nitrofurantoin	12	2.1	2.1
Metformin	255	2.1	2.1
Instalax Polyethylene Glycol 3350	9	2.1	2.1
Ciprofloxacin Hydrochloride And Hydrocortisone	15	2.1	2.1
Nitrofurantoin (Monohydrate/Macrocrystals)	12	2.0	2.0
Loratadine Oral	35	2.0	2.0
Linagliptin	13	2.0	2.0
Polyethylene Glycol 400	9	2.0	2.0
Sildenafil	41	2.0	2.0
Piperacillin And Tazobactam	9	2.0	2.0
Mirtazapine	64	2.0	2.0
Naproxen Sodium Tablet	37	2.0	2.0
Calcitriol Capsules 0.25 Mcg	14	2.0	2.0
Calcitriol Capsules 0.5 Mcg	14	2.0	2.0
Calcitriol	14	2.0	2.0
Naproxen Sodium	98	2.0	2.0
Metoclopramide Hydrochloride	53	2.0	2.0
Oxycodone And Acetaminophen	16	2.0	2.0
Atorvastatin Calcium, Film Coated	48	2.0	2.0
Sodium Chloride	54	1.9	2.0
Raloxifene Hydrochloride	10	1.9	1.9
Loratadine Tablet	36	1.9	1.9
Ranolazine	7	1.9	1.9
Obinutuzumab	11	1.9	1.9
Sodium Chloride Tablet	49	1.9	1.9
Sodium Chloride Tablets	49	1.9	1.9
Fexofenadine	11	1.9	1.9
Benzonatate	11	1.9	1.9
Filgrastim	25	1.9	1.9
Esomeprazole Magnesium	153	1.9	1.9
Thyroid, Porcine	7	1.9	1.9
Gabapentin	236	1.9	1.9
Bicalutamide	10	1.9	1.9
Alprazolam	134	1.9	1.9
Loratadine	70	1.9	1.9
Ursodiol	14	1.8	1.8
Doxorubicin	57	1.8	1.8
Cetuximab	20	1.8	1.8
Panitumumab	10	1.8	1.8
Carboxymethylcellulose Sodium	6	1.8	1.8
Tamsulosin Hydrochloride	13	1.8	1.8
Buspirone Hydrochloride	7	1.8	1.8
Ondansetron	69	1.8	1.8
Ondansetron Tablets	69	1.8	1.8
Lansoprazole	112	1.8	1.8
Cefepime	9	1.8	1.8
Mesalamine	35	1.8	1.8
Irinotecan Hydrochloride	8	1.8	1.8
Loperamide Hcl	8	1.8	1.8
Riociguat	20	1.7	1.7
Vancomycin Hydrochloride	40	1.7	1.7
Oxaliplatin	44	1.7	1.7
Diclofenac Potassium, Film Coated	5	1.7	1.7
Diclofenac Potassium Tablets	5	1.7	1.7
Nebivolol Hydrochloride	20	1.7	1.7
Ibuprofen Tablets, Coated	25	1.7	1.7
Tramadol Hydrochloride	22	1.7	1.7
Ibuprofen Sodium	25	1.7	1.7
Doxorubicin Hydrochloride	19	1.7	1.7
Lenvatinib	19	1.6	1.6
Voclosporin	5	1.6	1.6
Brinzolamide	5	1.6	1.6
Linezolid	17	1.6	1.6
Gefitinib	5	1.6	1.6
Sildenafil Citrate	70	1.6	1.6
Pemetrexed Disodium	21	1.6	1.6
Daptomycin	5	1.5	1.5
Prochlorperazine	15	1.5	1.5
Olaparib	11	1.5	1.5
Insulin Glargine	128	1.5	1.5
Vincristine Sulfate	15	1.5	1.5
Liraglutide	25	1.4	1.4
Cyclophosphamide Injection, Solution	87	1.4	1.4
Cyclophosphamide	87	1.4	1.4
Cyclophosphamide For Injection	87	1.4	1.4
Gemcitabine Hydrochloride	26	1.4	1.4
Metformin Hcl	27	1.4	1.4
Abiraterone Acetate	20	1.4	1.4
Rifaximin	10	1.4	1.4
Eszopiclone	12	1.3	1.3
Pemetrexed	10	1.3	1.3
Alteplase	7	1.3	1.3
Selexipag	12	1.3	1.3
Diclofenac Potassium	5	1.3	1.3
Travoprost	4	1.3	1.3
Fesoterodine Fumarate	5	1.3	1.3
Cisplatin	36	1.3	1.3
Miconazole Nitrate	4	1.3	1.3
Carboplatin	58	1.3	1.3
Gemcitabine	18	1.3	1.3
Bosentan	23	1.3	1.3
Nivolumab	44	1.3	1.3
Methoxy Polyethylene Glycol-Epoetin Beta	5	1.3	1.3
Linaclotide	12	1.3	1.3
Mometasone Furoate And Formoterol Fumarate Dihydrate	7	1.3	1.3
Carbidopa And Levodopa	21	1.3	1.3
Ifosfamide	9	1.2	1.2
Erlotinib	4	1.2	1.2
Polatuzumab Vedotin	4	1.2	1.2
Pegaspargase	5	1.2	1.2
Macitentan	28	1.1	1.1
Paclitaxel (Aibumin-Bound)	33	1.1	1.1
Daratumumab	16	1.1	1.1
Erlotinib Hydrochloride	5	1.1	1.1
Romiplostim	6	1.1	1.1
Paclitaxel	39	1.1	1.1
Durvalumab	8	1.1	1.1
Isotretinoin	18	1.0	1.0
Pembrolizumab	38	1.0	1.0
Emtricitabine And Tenofovir Alafenamide	4	1.0	1.0
Acetaminophen, Aspirin (Nsaid) And Caffeine	6	1.0	1.0
Selinexor	3	1.0	1.0
Enzalutamide	20	1.0	1.0
Ranitidine	67	1.0	1.0
Vemurafenib	4	0.9	0.9
Temozolomide	7	0.9	0.9
Treprostinil	41	0.9	0.9
Docetaxel Anhydrous	22	0.9	0.9
Docetaxel	22	0.9	0.9
Emicizumab	4	0.9	0.9
Ambrisentan	40	0.9	0.9
Carfilzomib	9	0.9	0.9
Bimatoprost	9	0.9	0.9
Axitinib	6	0.9	0.9
Venetoclax	18	0.8	0.8
Aflibercept	7	0.6	0.6
Hydrocodone Bitartrate	8	0.5	0.5
Cinacalcet Hydrochloride	7	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.