Reaction

Breath Sounds Abnormal reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,869 reports · 426 co-occurring drugs

As of the last recalculation, Breath Sounds Abnormal appears in 4,869 FAERS reports alongside 426 co-occurring drug terms. The strongest observed disproportionality signal is CICLESONIDE (PRR 126.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ciclesonide	372	126.3	129.9
Acetylcysteine	140	65.4	66.3
Mepolizumab	496	47.4	47.9
Oseltamivir Phosphate	249	45.9	46.3
Azithromycin Monohydrate	372	41.2	41.6
Doxyclycline Hyclate	149	38.6	38.9
Theophylline Anhydrous	108	38.1	38.4
Theophylline	100	38.0	38.3
Azithromycin	325	36.9	37.2
Budesonide	452	36.0	36.3
Ipratropium Bromide	260	32.9	33.1
Omalizumab	561	31.7	31.9
Ceftriaxone Sodium	262	30.8	31.0
Azithromycin Dihydrate	385	30.4	30.6
Montelukast Sodium	663	26.8	26.9
Phytonadione	51	26.0	26.1
Telmisartan	97	23.7	23.8
Albuterol	580	23.3	23.4
Budesonide And Formoterol Fumarate Dihydrate	478	23.2	23.3
Fluticasone Furoate	62	22.1	22.3
Fluticasone Propionate And Salmeterol Xinafoate	288	21.7	21.8
Risedronate Sodium	150	21.3	21.4
Esomeprazole Magnesium Capsule, Delayed Release	71	21.2	21.3
Esomeprazole Magnesium Delayed Release Capsules	71	21.2	21.3
Esomeprazole Magnesium Dihydrate	71	21.1	21.2
Pramipexole	74	20.9	21.0
Cyanocobalamin	155	20.7	20.8
Oseltamivir	38	20.6	20.6
Tamsulosin Hydrochloride	95	20.3	20.4
Eplerenone	60	20.3	20.4
Dextrose	61	20.0	20.1
Iron Sucrose	44	19.9	20.0
Dextrose Monohydrate	61	19.7	19.8
Amiodarone Hydrochloride	51	19.7	19.7
Albuterol Sulfate	1,035	18.7	18.7
Tiotropium Bromide	533	18.6	18.6
Magnesium Oxide	166	17.5	17.6
Instalax Polyethylene Glycol 3350	50	17.4	17.5
Tiotropium Bromide Inhalation Spray	45	17.3	17.4
Dalteparin Sodium	42	17.1	17.2
Polyethylene Glycol 400	50	17.0	17.1
Doxycycline Hyclate	250	16.6	16.7
Naproxen Sodium Tablet, Coated	52	16.6	16.6
Naproxen Sodium, Coated Tablets	52	16.6	16.6
Naproxen Sodium 220Mg	52	16.6	16.6
Doxycycline	250	16.5	16.5
Biscodyl	48	15.9	15.9
Bisacodyl Suppositories	47	15.7	15.7
Chlorthalidone	42	15.6	15.6
Norepinephrine Bitartrate	50	15.0	15.0
Bisacodyl	48	14.7	14.8
Melatonin	177	14.4	14.4
Fluticasone Furoate And Vilanterol Trifenatate	115	14.0	14.0
Polyethylene Glycol	34	13.5	13.6
Rosuvastatin Calcium	87	13.4	13.5
Calcitriol Capsules 0.25 Mcg	62	13.4	13.4
Calcitriol Capsules 0.5 Mcg	62	13.4	13.4
Calcitriol	62	13.2	13.3
Pantoprazole Sodium In 0.9% Sodium Chloride	181	12.9	13.0
Pantoprazole Sodium Injection	181	12.9	13.0
Tofacitinib Citrate	39	12.8	12.8
Docusate Sodium 100Mg	69	12.5	12.5
Mometasone Furoate	115	12.1	12.1
Ramipril	315	11.6	11.6
Umeclidinium	24	11.5	11.5
Metolazone	30	11.5	11.5
Salmeterol Xinafoate	23	11.5	11.5
Prednisone	1,058	11.2	11.2
0Xygen	126	11.2	11.2
Oxygen	126	11.2	11.2
Mesalamine	141	11.0	11.0
Montelukast	208	11.0	11.0
Levofloxacin	151	11.0	11.0
Levofloxacin In 5% Dextrose	151	11.0	11.0
Heparin Sodium	35	11.0	11.0
Digoxin	161	9.9	9.9
Diphenhydramine Hydrochloride Capsule, Liquid Filled	48	9.7	9.7
Palivizumab	34	9.5	9.5
Guaifenesin	66	9.4	9.4
Erlotinib	21	9.3	9.3
Nitroglycerin	114	9.3	9.3
Esomeprazole	131	9.3	9.3
Paroxetine Hydrochloride Hemihydrate	71	9.2	9.2
Naproxen	162	9.1	9.1
Potassium Chloride, Dextrose Monohydrate	190	9.1	9.1
Potassium Chloride Oral	190	9.1	9.1
Potassium Chloride Extended-Release	190	9.1	9.1
Paroxetine	71	9.0	9.1
Budesonide, Glycopyrrolate, And Formoterol Fumarate	22	9.0	9.1
Paroxetine Hydrochloride	184	8.9	9.0
Erlotinib Hydrochloride	26	8.9	8.9
Iron	133	8.7	8.7
Valsartan And Hydrochlorothiazide	27	8.5	8.6
Nitrofurantoin (Monohydrate/Macrocrystals)	33	8.5	8.5
Nitrofurantoin	32	8.3	8.4
Amlodipine Besylate	271	8.3	8.3
Ceftriaxone	63	8.3	8.3
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	39	8.2	8.2
Naproxen Sodium, Pseudoephedrine Hydrochloride	39	8.2	8.2
Potassium Chloride	208	8.1	8.1
Sennosides	56	8.1	8.1
Pantoprazole	441	8.1	8.1
Norepinephrine	20	8.0	8.0
Moxifloxacin	26	7.9	7.9
Antacid	86	7.9	7.9
Docusate Sodium	104	7.8	7.9
Calcium Gluconate	22	7.8	7.8
Riociguat	59	7.8	7.8
Pantoprazole Sodium	256	7.7	7.7
Bisoprolol Fumarate	234	7.7	7.7
Alendronate Sodium	175	7.7	7.7
Hydroxychloroquine	127	7.4	7.5
Mometasone	31	7.3	7.3
Sodium Chloride Tablet	122	7.2	7.3
Sodium Chloride Tablets	122	7.2	7.3
Moxifloxacin Hydrochloride	34	7.2	7.2
Propranolol Hydrochloride	119	7.2	7.2
Torsemide	55	7.2	7.2
Bendamustine Hydrochloride	20	7.2	7.2
Calcium Carbonate	108	7.0	7.0
Magnesium Hydroxide	22	7.0	7.0
Sodium Chloride	126	7.0	7.0
Fluticasone Propionate Nasal	49	7.0	7.0
Rabeprazole	35	6.8	6.8
Valsartan Oral	85	6.8	6.8
Sulfasalazine	120	6.7	6.7
Bendamustine Hcl	24	6.6	6.7
Dexlansoprazole	63	6.5	6.5
Standardized Senna Concentrate	19	6.5	6.5
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	62	6.5	6.5
Bumetanide	39	6.4	6.4
Leflunomide	151	6.3	6.3
Nystatin	40	6.3	6.3
Cetirizine Hydrochloride Allergy	44	6.3	6.3
Cetirizine Hydrochloride Tablets	44	6.3	6.3
Nystatin Ointment	38	6.2	6.2
Cimetidine	14	6.2	6.2
Nystatin Cream	38	6.2	6.2
Candesartan	51	6.2	6.2
Pregabalin	365	6.1	6.1
Diltiazem Hydrochloride	49	6.1	6.1
Sodium Bicarbonate	33	6.1	6.1
Sodium Bicarbonate Injection,	33	6.1	6.1
Psyllium Husk	14	6.1	6.1
Meperidine Hydrochloride	13	6.0	6.1
Morphine Sulfate	164	5.9	6.0
Spironolactone	188	5.9	5.9
Naproxen Sodium	189	5.8	5.8
Azathioprine	118	5.8	5.8
Biotin	42	5.8	5.8
Captopril	13	5.8	5.8
Dimenhydrinate	14	5.6	5.6
Sertraline Hydrochloride	152	5.6	5.6
Amlodipine	333	5.6	5.6
Promethazine Hydrochloride	24	5.5	5.5
Darbepoetin Alfa	69	5.5	5.5
Meclizine	21	5.5	5.5
Metronidazole	81	5.5	5.5
Umeclidinium Bromide And Vilanterol Trifenatate	21	5.4	5.4
Acetaminophen Tablet Extended Release	305	5.4	5.4
Pain Reliever	305	5.4	5.4
Acetaminophen 500Mg	305	5.4	5.4
Cyclobenzaprine	62	5.4	5.4
Ascorbic Acid	29	5.4	5.4
Hydroxychloroquine Sulfate	112	5.4	5.4
Meclizine Hcl 12.5Mg	17	5.3	5.4
Meclizine Hcl 25Mg	17	5.3	5.4
Metronidazole Topical	59	5.3	5.4
Meclizine Hcl 12.5 Mg	17	5.3	5.4
Meclizine Hcl 25 Mg	17	5.3	5.4
Treprostinil	152	5.3	5.3
Golimumab	104	5.3	5.3
Atenolol	159	5.2	5.2
Benzonatate	20	5.2	5.2
Tocilizumab	135	5.2	5.2
Ampicillin	10	5.2	5.2
Ampicillin Sodium	10	5.2	5.2
Atropine	10	5.2	5.2
Celecoxib	155	5.2	5.2
Losartan Potassium And Hydrochlorothiazide	14	5.2	5.2
Hydrochlorothiazide	168	5.1	5.1
Isosorbide Dinitrate	23	5.1	5.1
Meclizine Hydrochloride	23	5.0	5.0
Lisinopril And Hydrochlorothiazide	12	5.0	5.0
Carvedilol	155	5.0	5.0
Valsartan	121	5.0	5.0
Hydrocortisone	103	5.0	5.0
Clarithromycin	40	5.0	5.0
Fluticasone Propionate	148	5.0	5.0
Docusate Sodium - Sennosides	37	4.9	4.9
Methylprednisolone Sodium Succinate	52	4.8	4.8
Erythropoietin	23	4.8	4.8
Ezetimibe And Simvastatin	17	4.8	4.8
Epoetin Alfa	13	4.7	4.7
Furosemide	410	4.7	4.7
Folic Acid	261	4.7	4.7
Lidicaine	53	4.7	4.7
Burn Relief	53	4.7	4.7
Adrenalinum	45	4.7	4.7
Lidocaine Hydrochloride And Epinephrine	53	4.7	4.7
Selexipag	28	4.7	4.7
Aspirin 325 Mg	507	4.6	4.6
Aspirin 81 Mg	507	4.6	4.6
Lidocaine, Menthol	53	4.6	4.6
Ergocalciferol	387	4.6	4.6
Epoprostenol	14	4.6	4.6
Hydrocortisone Sodium Succinate	10	4.6	4.6
Warfarin Sodium	49	4.6	4.6
Simvastatin	253	4.5	4.5
Sertraline	121	4.5	4.5
Aspirin	518	4.5	4.5
Senna	22	4.5	4.5
Hydrocortisone Acetate	75	4.5	4.5
Lidocaine Hydrochloride And Epinephrine Bitartrate	55	4.4	4.4
Colchicine	27	4.4	4.4
Insulin Degludec	24	4.4	4.4
Clindamycin	29	4.4	4.4
Atropine Sulfate	11	4.4	4.4
Lisinopril And Hydrochlorothiazide Tablets	8	4.4	4.4
Fluticasone Propionate And Salmeterol	42	4.3	4.3
Enalapril Maleate	25	4.3	4.3
Allopurinol	154	4.3	4.3
Sennosides 8.6 Mg Tablets	21	4.3	4.3
Acetaminophen	420	4.3	4.3
Tobramycin Solution	12	4.3	4.3
Senna Leaf	23	4.3	4.3
Lidocaine 4%	54	4.3	4.3
Buspirone Hydrochloride	11	4.3	4.3
Diphenhydramine Hydrochloride	160	4.2	4.2
Polyethylene Glycol 3350	93	4.2	4.2
Finasteride	59	4.2	4.2
Lidocaine	57	4.2	4.2
Dexamethasone Sodium Phosphate	10	4.2	4.2
Dicyclomine Hydrochloride	14	4.2	4.2
Deferasirox	26	4.2	4.2
Cetirizine Hcl	9	4.2	4.2
Enoxaparin Sodium	56	4.2	4.2
Warfarin	122	4.2	4.2
Cephalexin	21	4.2	4.2
Tadalafil	96	4.2	4.2
Duloxetine	67	4.2	4.2
Tobramycin Sulfate	12	4.2	4.2
Human Insulin	12	4.1	4.1
Tobramycin	23	4.1	4.1
Granisetron Hydrochloride	10	4.1	4.1
Rituximab	196	4.1	4.1
Diclofenac Potassium, Film Coated	8	4.1	4.1
Diclofenac Potassium Tablets	8	4.1	4.1
Bupropion	42	4.1	4.1
Insulin Aspart	62	4.0	4.1
Bupropion Hydrochloride	92	4.0	4.0
Magnesium Sulfate In Water For	12	4.0	4.0
Nifedipine	44	4.0	4.0
Cetirizine	72	4.0	4.0
Cladribine	9	4.0	4.0
Lidocaine Hydrochloride	56	4.0	4.0
Hydromorphone Hydrochloride	85	4.0	4.0
Quinine	8	4.0	4.0
Clindamycin Phosphate	31	4.0	4.0
Rosuvastatin	184	4.0	4.0
Ixekizumab	34	3.9	4.0
Magnesium Sulfate Heptahydrate	12	3.9	3.9
Magnesium Sulfate	12	3.9	3.9
Atorvastatin Calcium, Film Coated	64	3.9	3.9
Alprazolam	184	3.9	3.9
Octreotide Acetate	28	3.9	3.9
Indomethacin	12	3.9	3.9
Abatacept	123	3.9	3.9
Cyclosporine	99	3.9	3.9
Ferrous Sulfate	45	3.9	3.9
Diphenhydramine Hcl	10	3.8	3.8
Indapamide	16	3.8	3.8
Tolterodine Tartrate	8	3.8	3.8
Calcium	130	3.8	3.8
Macitentan	61	3.8	3.8
Amoxicillin And Clavulanate Potassium	24	3.8	3.8
Loperamide Hydrochloride And Dimethicone	28	3.7	3.8
Esomeprazole Magnesium	198	3.7	3.7
Metoroprolol Tartrate	57	3.7	3.7
Glyburide	21	3.7	3.7
Piperacillin Sodium And Tazobactam Sodium	17	3.7	3.7
Amlodipine Besylate And Benazepril Hydrochloride	8	3.7	3.7
Fondaparinux Sodium	7	3.7	3.7
Niacin	10	3.7	3.7
Ondansetron Hydrochloride	104	3.7	3.7
Ibuprofen And Diphenhydramine Citrate	20	3.7	3.7
Midazolam Hydrochloride	23	3.7	3.7
Metoclopramide Hydrochloride	65	3.6	3.6
Epinephrine	55	3.6	3.6
Ciprofolxacin	60	3.6	3.6
Ciprofloxacin Tablets	60	3.6	3.6
Iohexol	7	3.6	3.6
Lactulose	32	3.6	3.6
Ciprofloxacin	76	3.6	3.6
Fluconazole	58	3.6	3.6
Vitamin E	26	3.5	3.5
Ciprofloxacin Hydrochloride	78	3.5	3.5
Isoniazid	13	3.4	3.4
Elexacaftor, Tezacaftor, And Ivacaftor	10	3.4	3.4
Diphenhydramine	50	3.4	3.4
Fexofenadine	13	3.4	3.4
Levothyroxine Sodium Anhydrous	78	3.4	3.4
Leucovorin Calcium	15	3.4	3.4
Meropenem	25	3.3	3.3
Estrogens, Conjugated	46	3.3	3.3
Methocarbamol Tablets	13	3.3	3.3
Ciprofloxacin Hydrochloride And Hydrocortisone	16	3.3	3.3
Vitamin C	70	3.3	3.3
Trazodone Hydrochloride	12	3.3	3.3
Granisetron	8	3.3	3.3
Dofetilide	8	3.3	3.3
Conjugated Estrogens	44	3.2	3.2
Midazolam	19	3.2	3.2
Pyrazinamide	7	3.2	3.2
Propofol	27	3.2	3.2
Diclofenac Potassium	8	3.2	3.2
Cetirizine Hydrochloride	120	3.2	3.2
Metformin Hydrochloride Tablets	42	3.1	3.2
Metformin Hydrochloride Extended-Release Tablets	42	3.1	3.2
Metformin Hydrochloride Tablet	42	3.1	3.2
Tofacitinib	133	3.1	3.1
Metformin Hydrochloride	43	3.1	3.1
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	36	3.1	3.1
Doxazosin	20	3.1	3.1
Vancomycin	41	3.0	3.1
Ondansetron	77	3.0	3.0
Ondansetron Tablets	77	3.0	3.0
Zolpidem Tartrate	94	3.0	3.0
Nintedanib	22	3.0	3.0
Insulin	39	3.0	3.0
Alendronate Sodium Tablet	13	3.0	3.0
Amoxicillin	53	3.0	3.0
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	110	3.0	3.0
Infliximab	149	3.0	3.0
Loperamide Hydrochloride	31	3.0	3.0
Metoclopramide	38	3.0	3.0
Filgrastim	26	3.0	3.0
Metoprolol Succinate Er Tablets	43	3.0	3.0
Rifampicin	7	3.0	3.0
Nebivolol	11	3.0	3.0
Mycophenolic Acid	22	2.9	2.9
Gentamicin	9	2.9	2.9
Vancomycin Hydrochloride	45	2.9	2.9
Itraconazole	8	2.9	2.9
Metformin	233	2.9	2.9
Certolizumab Pegol	78	2.9	2.9
Olmesartan Medoxomil	24	2.9	2.9
Doxazosin Mesylate	24	2.9	2.9
Tramadol Hydrochloride	25	2.8	2.8
Dornase Alfa	13	2.8	2.8
Levodopa	8	2.8	2.8
Fosaprepitant Dimeglumine	9	2.8	2.8
Metoprolol Tartrate	175	2.8	2.8
Metformin Er 500 Mg	191	2.8	2.8
Metformin Er 750 Mg	191	2.8	2.8
Losartan Potassium	51	2.8	2.8
Canakinumab	7	2.8	2.8
Amikacin	11	2.8	2.8
Varenicline Tartrate	51	2.7	2.7
Cetiirizine	27	2.7	2.7
Atorvastatin Calcium	155	2.7	2.7
Metoprolol Succinate	55	2.7	2.7
Quinapril Hydrochloride	5	2.7	2.7
Dorzolamide Hydrochloride And Timolol Maleate	5	2.7	2.7
Efavirenz	7	2.7	2.7
Voriconazole	19	2.7	2.7
Sildenafil	36	2.7	2.7
Metformin Hcl	34	2.6	2.6
Dutasteride	5	2.6	2.6
Azelastine	11	2.6	2.6
Voriconazole Injection	13	2.6	2.6
Aprepitant	11	2.6	2.6
Insulin Glargine-Yfgn	13	2.5	2.5
Sildenafil Citrate	75	2.5	2.5
Bicalutamide	9	2.5	2.5
Lovastatin	15	2.5	2.5
Ambrisentan	71	2.5	2.5
Sildenafil Powder,	20	2.4	2.4
Benralizumab	11	2.4	2.4
Loratadine Tablet	29	2.3	2.3
Prochlorperazine	15	2.3	2.3
Bortezomib	48	2.3	2.3
Fludarabine Phosphate	21	2.3	2.3
Sacubitril And Valsartan	61	2.3	2.3
Pemetrexed Disodium	20	2.2	2.2
Pertuzumab	14	2.2	2.2
Oxaliplatin	38	2.2	2.2
Rocuronium Bromide	6	2.2	2.2
Mesna Injection	4	2.1	2.1
Mesna	4	2.0	2.0
Micafungin Sodium	4	2.0	2.0
Pioglitazone	20	2.0	2.0
Miconazole Nitrate	4	2.0	2.0
Bosentan	23	2.0	2.0
Mometasone Furoate And Formoterol Fumarate Dihydrate	7	1.9	1.9
Rivaroxaban	91	1.9	1.9
Obinutuzumab	7	1.8	1.8
Paricalcitol	6	1.8	1.8
Trastuzumab	29	1.8	1.8
Tolvaptan	6	1.8	1.8
Polatuzumab Vedotin	4	1.8	1.8
Pegaspargase	5	1.7	1.7
Crizotinib	5	1.7	1.7
Gemcitabine	15	1.6	1.6
Ivacaftor	3	1.6	1.6
Sevoflurane	3	1.5	1.5
Venetoclax	22	1.5	1.5
Bimatoprost	10	1.5	1.5
Rifaximin	7	1.4	1.4
Alteplase	5	1.4	1.4
Secukinumab	53	1.4	1.4
Daptomycin	3	1.4	1.4
Agalsidase Beta	3	1.4	1.4
Cortisone Acetate	4	1.4	1.4
Hydrocodone Bitartrate	14	1.4	1.4
Pirfenidone	13	1.4	1.4
Etanercept	179	1.3	1.3
Ethyl Alcohol	8	1.3	1.3
Ranolazine	3	1.2	1.2
Vigabatrin	4	1.2	1.2
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	7	1.0	1.0
Remdesivir	3	1.0	1.0
Valbenazine	5	0.8	0.8
Nirmatrelvir And Ritonavir	8	0.6	0.6
Pimavanserin Tartrate	7	0.5	0.5
Dupilumab	53	0.5	0.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.