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Which drugs are most reported with Gingival pain?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,860 reports · 463 co-occurring drugs

As of the last recalculation, Gingival Pain appears in 7,860 FAERS reports alongside 463 co-occurring drug terms. The strongest observed disproportionality signal is FELODIPINE EXTENDED-RELEASE TABLETS (PRR 38.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Felodipine Extended-Release Tablets	162	38.4	39.0
Felodipine	162	38.4	39.0
Fesoterodine Fumarate	144	35.8	36.3
Nitrofurantoin	132	21.5	21.7
Nitrofurantoin (Monohydrate/Macrocrystals)	132	21.3	21.4
Tofacitinib Citrate	74	15.1	15.2
Desoximetasone	102	14.3	14.4
Dapagliflozin	162	13.9	14.0
Nicotine Polacrilex	189	13.4	13.4
Sunitinib Malate	186	12.8	12.9
Tamsulosin Hydrochloride	94	12.3	12.4
Chlorhexidine Gluconate	41	11.9	12.0
Cabozantinib	202	11.4	11.4
Candesartan	149	11.3	11.3
Ado-Trastuzumab Emtansine	31	9.8	9.8
Latanoprost	170	9.1	9.2
Mesalamine	189	9.1	9.1
Lisdexamfetamine Dimesylate	111	9.0	9.0
Hydrocortisone Sodium Succinate	31	8.8	8.8
Adalimumab-Fkjp	150	8.7	8.7
Anti-Itch	214	8.7	8.7
Anti-Pruritic	214	8.7	8.7
Antipruritic (Anti-Itch)	214	8.7	8.7
Cool Relief Gel With Aloe	214	8.7	8.7
Drs. Hydrocortisone	214	8.7	8.7
Hydrocortisone Continuous Spray	214	8.7	8.7
Hydrocortisone Spray	214	8.7	8.7
Anti-Itch Cream	214	8.7	8.7
Hydrocortisone Lotion	214	8.7	8.7
Hydrocortisone Cream 1%	214	8.7	8.7
Hydrocortisone Cream 1/2%	214	8.7	8.7
Hydrocortisone 1%	214	8.7	8.7
Hydrocortisone Cream	214	8.6	8.6
Adalimumab-Aaty	150	8.5	8.6
Budesonide	182	8.4	8.4
Hydrocortisone Acetate	221	8.3	8.3
Adalimumab-Adaz	156	8.0	8.0
Infliximab-Dyyb	87	8.0	8.0
Esomeprazole	180	7.8	7.9
Standardized Senna Concentrate	37	7.8	7.8
Escitslopram	165	7.7	7.7
Warfarin Sodium	130	7.5	7.5
Pravastatin Sodium	54	7.3	7.3
Hydrocortisone	236	7.2	7.2
Escitalopram Oxalate	191	7.1	7.1
Dimenhydrinate	27	6.7	6.7
Ketoprofen	33	6.7	6.7
Cimetidine	24	6.6	6.6
Alendronate Sodium	233	6.3	6.3
Sulfasalazine	180	6.2	6.2
Fulvestrant	74	6.0	6.0
Empagliflozin	146	5.8	5.8
Vedolizumab	181	5.7	5.7
Denosumab	411	5.6	5.6
Zoledronic Acid	84	5.6	5.6
Instalax Polyethylene Glycol 3350	26	5.6	5.6
Adrenalinum	86	5.5	5.5
Alpelisib	18	5.5	5.5
Polyethylene Glycol 400	26	5.4	5.5
Risedronate Sodium	63	5.4	5.4
Atorvastatin Calcium, Film Coated	134	5.1	5.1
Exemestane	41	5.1	5.1
Docusate Sodium - Sennosides	61	5.0	5.0
Nicotine	76	5.0	5.0
Axitinib	36	4.9	4.9
Diphenoxylate Hydrochloride And Atropine Sulfate	25	4.8	4.9
Regorafenib	21	4.8	4.8
Ramipril	218	4.8	4.8
Escitalopram	246	4.8	4.8
Antacid	84	4.7	4.7
Calcium	250	4.6	4.6
Everolimus	87	4.6	4.6
Candesartan Cilexetil	45	4.6	4.6
Sorafenib	35	4.5	4.5
Terbinafine Hydrochloride	15	4.5	4.5
Levothyroxine Sodium Anhydrous	166	4.5	4.5
Rosuvastatin Calcium	47	4.4	4.4
Calcium Carbonate	111	4.4	4.4
Docusate Sodium	92	4.3	4.3
Lenvatinib	52	4.2	4.2
Pertuzumab	43	4.2	4.2
Palbociclib	149	4.2	4.2
Amlodipine Besylate	225	4.2	4.2
Peginterferon Alfa-2A	84	4.1	4.2
Bisacodyl	22	4.1	4.2
Warfarin	195	4.1	4.1
Niacin	18	4.1	4.1
Bisacodyl Suppositories	20	4.1	4.1
Nicotine Polacrilex Mini	23	4.1	4.1
Nicotine Polarilex	23	4.1	4.1
Biscodyl	20	4.1	4.1
Psyllium Husk	15	4.0	4.0
Niraparib	33	3.9	4.0
Magnesium	120	3.9	3.9
Romosozumab-Aqqg	20	3.9	3.9
Citalopram Hydrobromide	155	3.9	3.9
Rosuvastatin	292	3.9	3.9
Anastrozole	53	3.8	3.8
Atropine	12	3.8	3.8
Oxycodone	264	3.8	3.8
Epinephrine	93	3.8	3.8
Lansoprazole	245	3.7	3.7
Docusate Sodium 100Mg	33	3.7	3.7
Clindamycin	39	3.7	3.7
Esomeprazole Magnesium	313	3.6	3.7
Letrozole	84	3.6	3.6
Acetaminophen Tablet Extended Release	339	3.6	3.6
Pain Reliever	339	3.6	3.6
Acetaminophen 500Mg	339	3.6	3.6
Citalopram	184	3.6	3.6
Levothyroxine Sodium	412	3.6	3.6
Rabeprazole	30	3.6	3.6
Ciprofloxacin Hydrochloride And Hydrocortisone	28	3.6	3.6
Zinc	33	3.6	3.6
Zinc Chloride	33	3.5	3.5
Folic Acid	322	3.5	3.5
Clindamycin Phosphate	44	3.5	3.5
Bicalutamide	20	3.5	3.5
Butalbital, Acetaminophen, And Caffeine	14	3.5	3.5
Human Immunoglobulin G	27	3.5	3.5
Vitamin E	41	3.5	3.5
Amlodipine Besylate And Benazepril Hydrochloride	12	3.4	3.4
Phytonadione	11	3.4	3.4
Amlodipine	339	3.4	3.4
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	39	3.4	3.4
Lisinopril And Hydrochlorothiazide Tablets	10	3.4	3.4
Ergocalciferol	469	3.4	3.4
Zinc Gluconate	33	3.4	3.4
Trastuzumab	85	3.3	3.3
Nystatin	34	3.3	3.3
Promethazine Hydrochloride	23	3.3	3.3
Heparin Sodium	17	3.3	3.3
Nystatin Ointment	32	3.2	3.2
Nystatin Cream	32	3.2	3.2
Cyanocobalamin	40	3.2	3.2
Omeprazole	404	3.2	3.2
Bisoprolol Fumarate	162	3.2	3.2
Vitamin C	110	3.2	3.2
Omeprazole Magnesium	515	3.2	3.2
Atropine Sulfate	13	3.2	3.2
Extended Phenytoin Sodium	20	3.2	3.2
Alendronate Sodium Tablet	22	3.1	3.2
Magnesium Hydroxide	16	3.1	3.2
Ribociclib	37	3.1	3.1
Quinine	10	3.1	3.1
Raloxifene Hydrochloride	17	3.1	3.1
Acetaminophen	498	3.1	3.1
Tofacitinib	208	3.0	3.0
Rabeprazole Sodium	31	3.0	3.0
Loratadine And Pseudoephedrine Sulfate	9	3.0	3.0
Diphenhydramine Hydrochloride Capsule, Liquid Filled	24	3.0	3.0
Goserelin	15	3.0	3.0
Pazopanib Hydrochloride	30	2.9	2.9
Amoxicillin	84	2.9	2.9
Sennosides 8.6 Mg Tablets	23	2.9	2.9
Epoetin Alfa	13	2.9	2.9
Senna	23	2.9	2.9
Varenicline Tartrate	86	2.9	2.9
Lisinopril And Hydrochlorothiazide	11	2.9	2.9
Ascorbic Acid	25	2.9	2.9
Fluticasone Furoate	13	2.8	2.8
Erythropoietin	22	2.8	2.8
Infliximab	229	2.8	2.8
Letrozole Tablets	51	2.8	2.8
Methylprednisolone Sodium Succinate	49	2.8	2.8
Gabapentin	371	2.8	2.8
Ribavirin	67	2.8	2.8
Salmeterol Xinafoate	9	2.8	2.8
Senna Leaf	24	2.8	2.8
Cladribine	10	2.8	2.8
Pregabalin	276	2.7	2.7
Atorvastatin Calcium	251	2.7	2.7
Alemtuzumab	20	2.7	2.7
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	163	2.7	2.7
Anastrozole Tablets	22	2.7	2.7
Cetiirizine	43	2.7	2.7
Ketoconazole Foam	15	2.7	2.7
Tramadol Hydrochloride	38	2.7	2.7
Ketoconazole Cream, 2%	15	2.7	2.7
Teriparatide	113	2.7	2.7
Temazepam	38	2.7	2.7
Thalidomide	37	2.7	2.7
Umeclidinium	9	2.7	2.7
Buprenorphine Hydrochloride, Naloxone Hydrochloride	24	2.6	2.6
Biotin	31	2.6	2.6
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	49	2.6	2.6
Melatonin	53	2.6	2.6
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	20	2.6	2.6
Naproxen Sodium, Pseudoephedrine Hydrochloride	20	2.6	2.6
Cortisone Acetate	12	2.6	2.6
Sennosides	29	2.6	2.6
Clobetasol Propionate Ointment Usp, 0.05%	10	2.6	2.6
Clobetasol Propionate	10	2.6	2.6
Esomeprazole Magnesium Capsule, Delayed Release	14	2.6	2.6
Esomeprazole Magnesium Delayed Release Capsules	14	2.6	2.6
Esomeprazole Magnesium Dihydrate	14	2.5	2.5
Sucralfate	23	2.5	2.5
Prednisone	465	2.5	2.5
Diphenhydramine Hydrochloride	157	2.5	2.5
Metformin Er 500 Mg	280	2.5	2.5
Metformin Er 750 Mg	280	2.5	2.5
Ibuprofen And Diphenhydramine Citrate	22	2.5	2.5
Thyroid, Porcine	10	2.5	2.5
Fish Oil	84	2.5	2.5
Aspirin 325 Mg	461	2.5	2.5
Aspirin 81 Mg	461	2.5	2.5
Methocarbamol	21	2.5	2.5
Capecitabine	84	2.4	2.4
Aspirin	476	2.4	2.4
Morphine	68	2.4	2.4
Dicyclomine Hydrochloride	13	2.4	2.4
Prochlorperazine	25	2.4	2.4
Metformin	315	2.4	2.4
Testosterone	21	2.4	2.4
Methotrexate	367	2.4	2.4
Trazodone Hydrochloride	14	2.4	2.4
Everolimus Tablets	15	2.4	2.4
Tolterodine Tartrate	8	2.4	2.4
Cyclobenzaprine Hydrochloride	8	2.4	2.4
Rivaroxaban	182	2.3	2.3
Alprazolam	180	2.3	2.3
Octreotide Acetate	27	2.3	2.3
Hydrochlorothiazide	127	2.3	2.3
Zolpidem Tartrate	118	2.3	2.3
Oseltamivir	7	2.3	2.3
Metoclopramide	48	2.3	2.3
Theophylline	10	2.3	2.3
Meclizine Hydrochloride	17	2.3	2.3
Prochlorperazine Maleate	8	2.3	2.3
Ketoconazole	15	2.3	2.3
Fluticasone Propionate Nasal	26	2.3	2.3
Meclizine	14	2.3	2.3
Lovastatin	22	2.3	2.3
Methotrexate Sodium	405	2.3	2.3
Ezetimibe And Simvastatin	13	2.3	2.3
Atenolol	113	2.3	2.3
Guaifenesin	26	2.3	2.3
Losartan Potassium	67	2.3	2.3
Furosemide	333	2.3	2.3
Abaloparatide	25	2.3	2.3
Metronidazole	54	2.2	2.2
Fexofenadine	14	2.2	2.2
Ibuprofen Sodium	36	2.2	2.2
Desloratadine	9	2.2	2.2
Melphalan	19	2.2	2.2
Azelastine	15	2.2	2.2
Lidocaine Hydrochloride	50	2.2	2.2
Cholestyramine	10	2.2	2.2
Ibuprofen Tablets, Coated	35	2.2	2.2
Mometasone	15	2.2	2.2
Amlodipine Besylate And Valsartan	9	2.2	2.2
Diphenhydramine	51	2.1	2.1
Nifedipine	38	2.1	2.1
Theophylline Anhydrous	10	2.1	2.1
Cetirizine	62	2.1	2.1
Multivitamin	40	2.1	2.1
Human Insulin	10	2.1	2.1
Oxybutynin Chloride	7	2.1	2.1
Hydroxyzine	38	2.1	2.1
Melphalan Hydrochloride	20	2.1	2.1
Ferrous Sulfate	40	2.1	2.1
Metoclopramide Hydrochloride	61	2.1	2.1
Doxepin Hydrochloride	10	2.1	2.1
Famotidine	92	2.1	2.1
Prasugrel Hydrochloride	8	2.1	2.1
Febuxostat Tablets 40 Mg	8	2.1	2.1
Febuxostat Tablets 80 Mg	8	2.1	2.1
Rizatriptan Benzoate	8	2.1	2.1
Irbesartan	35	2.1	2.1
Fluticasone Propionate	101	2.1	2.1
Darbepoetin Alfa	42	2.1	2.1
Celecoxib	102	2.1	2.1
Methocarbamol Tablets	13	2.1	2.1
Losartan Potassium And Hydrochlorothiazide	9	2.1	2.1
Lapatinib	12	2.0	2.1
Prednisolone Acetate	8	2.0	2.0
Mometasone Furoate	32	2.0	2.0
Fluticasone Propionate And Salmeterol Xinafoate	46	2.0	2.0
Polyethylene Glycol 3350	73	2.0	2.0
Enalapril Maleate	19	2.0	2.0
Doxycycline	52	2.0	2.0
Metoroprolol Tartrate	50	2.0	2.0
Meloxicam	44	2.0	2.0
Fexofenadine Hcl	7	2.0	2.0
Fluticasone Furoate And Vilanterol Trifenatate	27	2.0	2.0
Eszopiclone	19	2.0	2.0
Potassium Chloride	84	2.0	2.0
Cetirizine Hydrochloride	121	2.0	2.0
Naproxen Sodium Tablet, Coated	10	2.0	2.0
Naproxen Sodium, Coated Tablets	10	2.0	2.0
Dutasteride	6	2.0	2.0
Naproxen Sodium 220Mg	10	2.0	2.0
Valsartan And Hydrochlorothiazide	10	2.0	2.0
Metronidazole Topical	35	1.9	2.0
Posaconazole Delayed-Release	8	1.9	1.9
Doxycycline Hyclate	49	1.9	1.9
Estrogens, Conjugated	43	1.9	1.9
Cyclobenzaprine	36	1.9	1.9
Acyclovir	82	1.9	1.9
Tiotropium Bromide	97	1.9	1.9
Metoprolol Tartrate	191	1.9	1.9
Doxyclycline Hyclate	12	1.9	1.9
Conjugated Estrogens	41	1.9	1.9
Aprepitant	13	1.9	1.9
Naproxen Sodium Tablet	37	1.9	1.9
Selexipag	18	1.8	1.8
Losartan	120	1.8	1.8
Voclosporin	6	1.8	1.8
Rucaparib	6	1.8	1.8
Ibuprofen	182	1.8	1.8
Terazosin Hydrochloride	6	1.8	1.8
Metoprolol	170	1.8	1.8
Fentanyl	66	1.8	1.8
Indapamide	12	1.8	1.8
Sirolimus	9	1.8	1.8
Isosorbide Dinitrate	13	1.8	1.8
Metformin Hydrochloride Tablets	38	1.8	1.8
Metformin Hydrochloride Extended-Release Tablets	38	1.8	1.8
Metformin Hydrochloride Tablet	38	1.8	1.8
Estradiol	57	1.8	1.8
Metoprolol Tartrate Injection	124	1.7	1.7
Febuxostat	11	1.7	1.7
Ezetimibe	49	1.7	1.7
Lisinopril	198	1.7	1.7
Modafinil	21	1.7	1.7
Abemaciclib	13	1.7	1.7
Bupropion Hydrochloride	64	1.7	1.7
Oxycodone Hydrochloride And Acetaminophen	64	1.7	1.7
Calcitriol Capsules 0.25 Mcg	13	1.7	1.7
Calcitriol Capsules 0.5 Mcg	13	1.7	1.7
Metoprolol Succinate	56	1.7	1.7
Montelukast	54	1.7	1.7
Doxazosin	18	1.7	1.7
Metformin Hydrochloride	38	1.7	1.7
Estradiol Gel 0.1%	29	1.7	1.7
Estradiol Transdermal	29	1.7	1.7
Triamcinolone Acetonide Ointment Usp, 0.05%	15	1.7	1.7
Olmesartan Medoxomil	23	1.7	1.7
Buspirone Hydrochloride	7	1.7	1.7
Paclitaxel (Aibumin-Bound)	52	1.7	1.7
Quinapril Hydrochloride	5	1.7	1.7
Duloxetine	44	1.7	1.7
Dorzolamide Hydrochloride And Timolol Maleate	5	1.7	1.7
Dexlansoprazole	26	1.7	1.7
Erlotinib	6	1.6	1.6
Fondaparinux Sodium	5	1.6	1.6
Armodafinil	13	1.6	1.6
Loratadine Tablet	33	1.6	1.6
Duloxetine Hydrochloride	115	1.6	1.6
Ondansetron Hydrochloride	75	1.6	1.6
Oxycodone Hydrochloride	132	1.6	1.6
Imatinib Mesylate	17	1.6	1.6
Budesonide And Formoterol Fumarate Dihydrate	59	1.6	1.6
Tocilizumab	69	1.6	1.6
Chlorthalidone	7	1.6	1.6
Adalimumab	417	1.6	1.6
Oxycodone And Acetaminophen	14	1.6	1.6
Fluticasone Propionate And Salmeterol	25	1.6	1.6
Umeclidinium Bromide And Vilanterol Trifenatate	10	1.6	1.6
Valacyclovir Hydrochloride	42	1.6	1.6
Ruxolitinib	42	1.6	1.6
Paclitaxel	58	1.6	1.6
Tizanidine	14	1.6	1.6
Triamcinolone Acetonide	18	1.5	1.5
Tobramycin Solution	7	1.5	1.5
Acalabrutinib	7	1.5	1.5
Loratadine	62	1.5	1.5
Bevacizumab	71	1.5	1.5
Ledipasvir And Sofosbuvir	11	1.5	1.5
Tobramycin Sulfate	7	1.5	1.5
Metformin Hcl	31	1.5	1.5
Trifluridine And Tipiracil	6	1.5	1.5
Canakinumab	6	1.5	1.5
Posaconazole	9	1.5	1.5
Lenalidomide	230	1.5	1.5
Ibrutinib	44	1.4	1.4
Dexamethasone	160	1.4	1.4
Dexamethasone 1.5 Mg	158	1.4	1.4
Nintedanib	17	1.4	1.4
Clobazam	13	1.4	1.4
Oseltamivir Phosphate	13	1.4	1.4
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	22	1.4	1.4
Eltrombopag Olamine	12	1.4	1.4
Teduglutide	7	1.4	1.4
Bimekizumab	11	1.4	1.4
Oxybutynin	15	1.4	1.4
Glipizide	30	1.3	1.3
Deferasirox	13	1.3	1.3
Docetaxel Anhydrous	33	1.3	1.3
Docetaxel	33	1.3	1.3
Lifitegrast	8	1.3	1.3
Desvenlafaxine Succinate	13	1.3	1.3
Erlotinib Hydrochloride	6	1.3	1.3
Blinatumomab	5	1.3	1.3
Fluorouracil	36	1.2	1.2
Orlistat	12	1.2	1.2
Pioglitazone	20	1.2	1.2
Brinzolamide	4	1.2	1.2
Fluorouracil Cream, 0.5%	35	1.2	1.2
Dasatinib	17	1.2	1.2
Ofatumumab	15	1.2	1.2
Brimonidine Tartrate	8	1.2	1.2
Bosutinib	4	1.2	1.2
Fremanezumab-Vfrm	5	1.2	1.2
Olaparib	9	1.1	1.1
Ixazomib	12	1.1	1.1
Fexofenadine Hydrochloride	9	1.1	1.1
Linaclotide	11	1.1	1.1
Nivolumab	39	1.1	1.1
Ocrelizumab	25	1.1	1.1
Botulinum Toxin Type A	5	1.1	1.1
Pomalidomide	41	1.1	1.1
Treprostinil	50	1.1	1.1
Teriflunomide	18	1.1	1.1
Pembrolizumab	41	1.0	1.0
Velpatasvir And Sofosbuvir	5	1.0	1.0
Etanercept	233	1.0	1.0
Irinotecan Hydrochloride	5	1.0	1.0
Atezolizumab	15	1.0	1.0
Paliperidone	9	1.0	1.0
Bimatoprost	11	1.0	1.0
Dofetilide	4	1.0	1.0
Pegfilgrastim	37	1.0	1.0
Osimertinib	12	1.0	1.0
Nirmatrelvir And Ritonavir	20	1.0	1.0
Secukinumab	58	1.0	1.0
Glycerin, Lidocaine	5	0.9	0.9
Acetaminophen, Aspirin (Nsaid) And Caffeine	6	0.9	0.9
Naltrexone Hydrochloride And Bupropion Hydrochloride	3	0.9	0.9
Selinexor	3	0.9	0.9
Asenapine Maleate	3	0.9	0.9
Docosanol	5	0.9	0.9
Vemurafenib	4	0.9	0.9
Acetaminophen, Aspirin, And Caffeine	7	0.9	0.9
Abatacept	46	0.9	0.9
Dabigatran Etexilate Mesylate	24	0.9	0.9
Dupilumab	159	0.9	0.9
Oral Semaglutide	24	0.9	0.9
Ixekizumab	12	0.9	0.9
Cariprazine	3	0.9	0.9
Dabigatran Etexilate	25	0.9	0.9
Onabotulinumtoxina	23	0.8	0.8
Fam-Trastuzumab Deruxtecan-Nxki	3	0.8	0.8
Relugolix	7	0.8	0.8
Enzalutamide	17	0.8	0.8
Ambrisentan	35	0.7	0.7
Buprenorphine	25	0.7	0.7
Abiraterone Acetate	11	0.7	0.7
Natalizumab	48	0.7	0.7
Benralizumab	5	0.7	0.7
Cenegermin-Bkbj	3	0.7	0.7
Exenatide	13	0.7	0.7
Valbenazine	6	0.6	0.6
Lutetium Lu 177 Vipivotide Tetraxetan	3	0.6	0.6
Sarilumab	6	0.6	0.6
Erenumab-Aooe	12	0.6	0.6
Hydrocodone Bitartrate	9	0.5	0.5
Tapentadol Hydrochloride	6	0.5	0.5
Evolocumab	23	0.4	0.4
Apremilast	20	0.4	0.4
Tirzepatide	22	0.4	0.4
Galcanezumab-Gnlm	4	0.3	0.3
Copper	3	0.2	0.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.