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Which drugs are most reported with Acute coronary syndrome?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 8,233 reports · 428 co-occurring drugs

As of the last recalculation, Acute Coronary Syndrome appears in 8,233 FAERS reports alongside 428 co-occurring drug terms. The strongest observed disproportionality signal is TICAGRELOR (PRR 16.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Ticagrelor	204	16.6	16.7
Clopidogrel Bisulfate	419	10.9	10.9
Clopidogrel	774	10.8	10.8
Abiraterone	53	9.9	9.9
Nitroglycerin	196	9.4	9.5
Nilotinib	107	9.3	9.3
Prasugrel Hydrochloride	34	8.5	8.5
Fluorouracil Cream, 0.5%	243	8.3	8.3
Fluorouracil	243	8.2	8.2
Oxaliplatin	224	7.8	7.8
Bisoprolol Fumarate	389	7.5	7.6
Isosorbide Mononitrate	61	7.5	7.5
Isosorbide Dinitrate	56	7.3	7.3
Abacavir Sulfate	26	6.8	6.8
Ramipril	304	6.4	6.4
Amlodipine Besylate And Benazepril Hydrochloride	23	6.3	6.3
Fondaparinux Sodium	20	6.3	6.3
Enalapril Maleate	60	6.2	6.2
Ipratropium Bromide	85	6.1	6.1
Inclisiran	19	6.0	6.0
Candesartan	80	5.7	5.7
Testosterone Cypionate	20	5.7	5.7
Norepinephrine Bitartrate	31	5.5	5.5
Nebivolol	34	5.4	5.4
Gemfibrozil	32	5.3	5.4
Abiraterone Acetate	86	5.3	5.3
Testosterone	49	5.3	5.3
Basiliximab	24	5.2	5.2
Bicalutamide	31	5.2	5.2
Glyburide	48	5.0	5.0
Aspirin 81 Mg	923	5.0	5.0
Aspirin 325 Mg	922	5.0	5.0
Norepinephrine	21	5.0	5.0
Sorafenib	40	4.9	4.9
Aspirin	938	4.9	4.9
Indapamide	34	4.8	4.8
Losartan Potassium And Hydrochlorothiazide	22	4.8	4.8
Iron Sucrose	18	4.8	4.8
Captopril	18	4.7	4.7
Febuxostat Tablets 40 Mg	19	4.7	4.7
Febuxostat Tablets 80 Mg	19	4.7	4.7
Felodipine Extended-Release Tablets	21	4.7	4.7
Felodipine	21	4.7	4.7
Ezetimibe And Simvastatin	28	4.7	4.7
Insulin	101	4.6	4.6
Ezetimibe	135	4.6	4.6
Pemetrexed Disodium	69	4.6	4.6
Capecitabine	164	4.6	4.6
Midazolam	45	4.5	4.5
Metoprolol Tartrate	466	4.5	4.5
Carfilzomib	50	4.5	4.5
Midazolam Hydrochloride	47	4.4	4.4
Bleomycin Sulfate	18	4.4	4.4
Diltiazem Hydrochloride	60	4.4	4.4
Enalapril	96	4.4	4.4
Metoprolol Tartrate Injection	317	4.4	4.4
Amlodipine Besylate And Valsartan	19	4.3	4.4
Rocuronium Bromide	20	4.3	4.3
Epoetin Alfa	20	4.3	4.3
Metoprolol	413	4.3	4.3
Romiplostim	25	4.2	4.2
Baricitinib	16	4.2	4.2
Salmeterol Xinafoate	14	4.1	4.1
Bevacizumab	195	4.1	4.1
Glipizide	96	4.0	4.0
Metformin Hcl	86	4.0	4.0
Pitavastatin Calcium	16	4.0	4.0
Enoxaparin Sodium	89	3.9	3.9
Axitinib	30	3.9	3.9
Misoprostol	15	3.9	3.9
Irbesartan	68	3.9	3.9
Darunavir	23	3.9	3.9
Human Insulin	19	3.9	3.9
Metoroprolol Tartrate	99	3.8	3.8
Simvastatin	366	3.8	3.8
Atorvastatin Calcium	361	3.8	3.8
Atenolol	196	3.8	3.8
Atorvastatin Calcium, Film Coated	102	3.7	3.7
Atropine	12	3.7	3.7
Ranolazine	15	3.6	3.6
Cisplatin	110	3.6	3.6
Bendamustine Hydrochloride	17	3.6	3.6
Rosuvastatin	283	3.6	3.6
Sennosides 8.6 Mg Tablets	29	3.5	3.5
Senna	29	3.5	3.5
Febuxostat	23	3.5	3.5
Candesartan Cilexetil	36	3.5	3.5
Brentuximab Vedotin	14	3.5	3.5
Pravastatin Sodium	27	3.5	3.5
Valacyclovir	56	3.4	3.4
Efavirenz	15	3.4	3.4
Nintedanib	42	3.4	3.4
Goserelin	18	3.4	3.4
Amiodarone Hydrochloride	15	3.4	3.4
Nebivolol Hydrochloride	45	3.4	3.4
Dalteparin Sodium	14	3.3	3.4
Chlorhexidine Gluconate	12	3.3	3.3
Torsemide	43	3.3	3.3
Methylprednisolone Sodium Succinate	60	3.3	3.3
Esomeprazole	80	3.3	3.3
Atropine Sulfate	14	3.3	3.3
Cetuximab	40	3.2	3.2
Fenofibrate	45	3.2	3.2
Sofosbuvir	25	3.2	3.2
Sumatriptan Succinate	32	3.2	3.2
Digoxin	90	3.2	3.2
Metformin Hydrochloride Tablets	72	3.2	3.2
Metformin Hydrochloride Extended-Release Tablets	72	3.2	3.2
Metformin Hydrochloride Tablet	72	3.2	3.2
Senna Leaf	29	3.2	3.2
Dabigatran Etexilate	97	3.2	3.2
Eplerenone	16	3.2	3.2
Cimetidine	12	3.2	3.2
Rosuvastatin Calcium	35	3.2	3.2
Metformin Hydrochloride	73	3.1	3.1
Dabigatran Etexilate Mesylate	89	3.1	3.1
Amitriptyline Hydrochloride	21	3.0	3.0
Doxazosin	33	3.0	3.0
Furosemide	452	3.0	3.0
Ritonavir	34	2.9	3.0
Pantoprazole	288	2.9	2.9
Sitagliptin And Metformin Hydrochloride	25	2.9	2.9
Gemcitabine Hydrochloride	61	2.9	2.9
Allopurinol	178	2.9	2.9
Gemcitabine	45	2.9	2.9
Erlotinib	11	2.9	2.9
Lansoprazole	196	2.8	2.8
Metformin	385	2.8	2.8
Atezolizumab	43	2.8	2.8
Canakinumab	12	2.8	2.8
Valsartan Oral	60	2.8	2.8
Valsartan	115	2.8	2.8
Leucovorin Calcium	21	2.8	2.8
Ranibizumab	29	2.8	2.8
Heparin Sodium	15	2.8	2.8
Amlodipine Besylate	158	2.8	2.8
Adrenalinum	45	2.8	2.8
Panitumumab	17	2.7	2.7
Doxazosin Mesylate	39	2.7	2.7
Insulin Glulisine	11	2.7	2.7
Imatinib	19	2.7	2.7
Lisinopril And Hydrochlorothiazide	11	2.7	2.7
Sennosides	32	2.7	2.7
Metformin Er 500 Mg	315	2.7	2.7
Metformin Er 750 Mg	315	2.7	2.7
Lenvatinib	35	2.7	2.7
Amoxicillin And Clavulanate Potassium	29	2.7	2.7
Amlodipine	282	2.7	2.7
Metoprolol Succinate	92	2.7	2.7
Meropenem	34	2.7	2.7
Acetylcysteine	10	2.7	2.7
Metoclopramide	58	2.7	2.7
Theophylline Anhydrous	13	2.7	2.7
Theophylline	12	2.6	2.6
Sotalol Hydrochloride	17	2.6	2.6
Carvedilol	137	2.6	2.6
Docetaxel Anhydrous	68	2.6	2.6
Docetaxel	68	2.6	2.6
Lisinopril	303	2.6	2.6
Irinotecan Hydrochloride	13	2.6	2.6
Ritonavir 100 Mg	15	2.5	2.5
Pazopanib Hydrochloride	27	2.5	2.5
Hydrochlorothiazide	143	2.5	2.5
Rabeprazole	22	2.5	2.5
Rasagiline Mesylate	11	2.5	2.5
Propofol	36	2.5	2.5
Dapagliflozin	31	2.5	2.5
Pembrolizumab	103	2.5	2.5
Durvalumab	20	2.5	2.5
Dutasteride	8	2.5	2.5
Indomethacin	13	2.5	2.5
Loperamide Hydrochloride Oral	10	2.5	2.5
Clonidine	50	2.5	2.5
Nifedipine	46	2.5	2.5
Sulfamethoxazole And Trimethoprim	82	2.5	2.5
Lovastatin	25	2.5	2.5
Erythropoietin	20	2.5	2.5
Agalsidase Beta	9	2.5	2.5
Obinutuzumab	16	2.5	2.5
Spironolactone	135	2.5	2.5
Melphalan	22	2.4	2.5
Diltiazem Hydrochloride Extended-Release Tablets	11	2.4	2.4
Sevoflurane	8	2.4	2.4
Cefuroxime	11	2.4	2.4
Valsartan And Hydrochlorothiazide	13	2.4	2.4
Meclizine Hcl 12.5Mg	13	2.4	2.4
Meclizine Hcl 25Mg	13	2.4	2.4
Meclizine Hcl 12.5 Mg	13	2.4	2.4
Meclizine Hcl 25 Mg	13	2.4	2.4
Telmisartan	17	2.4	2.4
Colchicine	25	2.4	2.4
Nivolumab	91	2.4	2.4
Piperacillin And Tazobactam	12	2.4	2.4
Quinine	8	2.4	2.4
Pioglitazone	40	2.3	2.3
Metoclopramide Hydrochloride	71	2.3	2.3
Carboplatin	116	2.3	2.3
Sitagliptin	66	2.3	2.3
Melphalan Hydrochloride	23	2.3	2.3
Fluconazole	64	2.3	2.3
Ceftriaxone	30	2.3	2.3
Vemurafenib	11	2.3	2.3
Calcium Gluconate	11	2.3	2.3
Valacyclovir Hydrochloride	64	2.3	2.3
Ondansetron	99	2.3	2.3
Ondansetron Tablets	99	2.3	2.3
Methoxy Polyethylene Glycol-Epoetin Beta	10	2.3	2.3
Filgrastim	34	2.3	2.3
Ixazomib	26	2.3	2.3
Daratumumab	36	2.3	2.3
Lidicaine	44	2.3	2.3
Burn Relief	44	2.3	2.3
Lidocaine Hydrochloride And Epinephrine	44	2.3	2.3
Paclitaxel (Aibumin-Bound)	73	2.3	2.3
Carisoprodol	17	2.3	2.3
Methimazole	7	2.3	2.3
Cyclophosphamide Injection, Solution	156	2.3	2.3
Cyclophosphamide	156	2.3	2.3
Cyclophosphamide For Injection	156	2.3	2.3
Lidocaine, Menthol	44	2.2	2.3
Lactulose	34	2.2	2.2
Vincristine Sulfate	26	2.2	2.2
Lopinavir And Ritonavir	12	2.2	2.2
Rizatriptan Benzoate	9	2.2	2.2
Metoprolol Succinate Er Tablets	55	2.2	2.2
Lidocaine Hydrochloride And Epinephrine Bitartrate	47	2.2	2.2
Rabeprazole Sodium	24	2.2	2.2
Erlotinib Hydrochloride	11	2.2	2.2
Oseltamivir	7	2.2	2.2
Ondansetron Hydrochloride	107	2.2	2.2
Hyoscyamine Sulfate	8	2.2	2.2
Meperidine Hydrochloride	8	2.2	2.2
Nicotine Polacrilex Mini	13	2.2	2.2
Nicotine Polarilex	13	2.2	2.2
Granisetron Hydrochloride	9	2.2	2.2
Granisetron	9	2.2	2.2
Dexamethasone 1.5 Mg	247	2.2	2.2
Darbepoetin Alfa	46	2.2	2.2
Dexamethasone	248	2.1	2.1
Raltegravir	14	2.1	2.1
Esomeprazole Magnesium	196	2.1	2.1
Mesna Injection	7	2.1	2.1
Iohexol	7	2.1	2.1
Linezolid	25	2.1	2.1
Doxorubicin	74	2.1	2.1
Etoposide	61	2.1	2.1
Lidocaine Hydrochloride	50	2.1	2.1
Mesna	7	2.1	2.1
Omeprazole	281	2.1	2.1
Ciprofolxacin	59	2.1	2.1
Ciprofloxacin Tablets	59	2.1	2.1
Acalabrutinib	10	2.1	2.1
Azacitidine For	15	2.1	2.1
Paclitaxel	81	2.1	2.1
Sodium Bicarbonate	19	2.1	2.1
Sodium Bicarbonate Injection,	19	2.1	2.1
Piperacillin Sodium And Tazobactam Sodium	16	2.1	2.1
Potassium Chloride, Dextrose Monohydrate	75	2.1	2.1
Potassium Chloride Oral	75	2.1	2.1
Potassium Chloride Extended-Release	75	2.1	2.1
Lidocaine 4%	44	2.0	2.0
Meclizine	13	2.0	2.0
Piperacillin Sodium,Tazobactam Sodium	21	2.0	2.0
Doxepin Hydrochloride	10	2.0	2.0
Nitrofurantoin	13	2.0	2.0
Tranexamic Acid	7	2.0	2.0
Ceftriaxone Sodium	30	2.0	2.0
Haloperidol	19	2.0	2.0
Levothyroxine Sodium Anhydrous	78	2.0	2.0
Bosutinib	7	2.0	2.0
Paricalcitol	11	2.0	2.0
Nitrofurantoin (Monohydrate/Macrocrystals)	13	2.0	2.0
Loperamide Hcl	10	2.0	2.0
Bortezomib	69	2.0	2.0
Bendamustine Hcl	12	2.0	2.0
Glimepiride	30	1.9	2.0
Prednisolone	138	1.9	2.0
Prednisolone Oral	138	1.9	2.0
Prednisolone Oral Solution	138	1.9	2.0
Aflibercept	24	1.9	1.9
Haloperidol Lactate	19	1.9	1.9
Cefazolin	7	1.9	1.9
Mirtazapine	70	1.9	1.9
Omeprazole Magnesium	336	1.9	1.9
Epinephrine	50	1.9	1.9
Lisinopril And Hydrochlorothiazide Tablets	6	1.9	1.9
Quinapril Hydrochloride	6	1.9	1.9
Hydroxyurea	16	1.9	1.9
Lidocaine	44	1.9	1.9
Warfarin Sodium	35	1.9	1.9
Potassium Chloride	85	1.9	1.9
Pantoprazole Sodium	110	1.9	1.9
Rivaroxaban	154	1.9	1.9
Desloratadine	8	1.9	1.9
Atovaquone	6	1.9	1.9
Oxazepam	16	1.9	1.9
Rituximab	156	1.9	1.9
Azacitidine	22	1.9	1.9
Isoniazid	12	1.9	1.9
Lubiprostone	7	1.9	1.9
Sumatriptan	28	1.9	1.9
Tamsulosin Hydrochloride	15	1.9	1.9
Apixaban	49	1.9	1.9
Ibuprofen And Diphenhydramine Citrate	17	1.8	1.8
Amphetamine	6	1.8	1.8
Mycophenilic Acid	15	1.8	1.8
Zoledronic Acid	29	1.8	1.8
Diphenhydramine Hcl	8	1.8	1.8
Metolazone	8	1.8	1.8
Lithium Carbonate	12	1.8	1.8
Calcitriol Capsules 0.25 Mcg	14	1.8	1.8
Calcitriol Capsules 0.5 Mcg	14	1.8	1.8
Ferrous Sulfate	35	1.8	1.8
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	21	1.8	1.8
Calcitriol	14	1.7	1.7
Dexamethasone Sodium Phosphate	7	1.7	1.7
Niacin	8	1.7	1.7
Mycophenolic Acid	22	1.7	1.7
Itraconazole	8	1.7	1.7
Apalutamide	8	1.7	1.7
Insulin Glargine	166	1.7	1.7
Terazosin Hydrochloride	6	1.7	1.7
Alprazolam	138	1.7	1.7
Losartan Potassium	53	1.7	1.7
Ipilimumab	29	1.7	1.7
Clarithromycin	23	1.7	1.7
Mepolizumab	33	1.7	1.7
Tramadol Hydrochloride	25	1.7	1.7
Cefazolin Sodium	8	1.7	1.7
Famotidine	77	1.7	1.7
Pegaspargase	8	1.7	1.7
Prochlorperazine Maleate	6	1.6	1.6
Duloxetine	45	1.6	1.6
Empagliflozin	42	1.6	1.6
Tolvaptan	9	1.6	1.6
Letrozole	38	1.6	1.6
Rifampin	9	1.6	1.6
Raloxifene Hydrochloride	9	1.6	1.6
Posaconazole	10	1.6	1.6
Lamivudine	19	1.6	1.6
Estrogens, Conjugated	36	1.5	1.5
Pemetrexed	13	1.5	1.5
Linagliptin	11	1.5	1.5
Alteplase	9	1.5	1.5
Trastuzumab	41	1.5	1.5
Dasatinib	22	1.5	1.5
Olanzapine	63	1.5	1.5
Letrozole Tablets	28	1.5	1.5
Timolol	7	1.5	1.5
Enzalutamide	34	1.5	1.5
Brinzolamide	5	1.5	1.5
Thalidomide	21	1.4	1.4
Conjugated Estrogens	33	1.4	1.4
Instalax Polyethylene Glycol 3350	7	1.4	1.4
Eltrombopag Olamine	13	1.4	1.4
Trifluridine And Tipiracil	6	1.4	1.4
Dolutegravir Sodium	5	1.4	1.4
Insulin Human	22	1.4	1.4
Polyethylene Glycol 400	7	1.4	1.4
Donepezil Hydrochloride	20	1.4	1.4
Zonisamide	8	1.4	1.4
Bupivacaine	5	1.4	1.4
Sunitinib Malate	21	1.4	1.4
Tiotropium Bromide	73	1.4	1.4
Ibrutinib	43	1.3	1.3
Pyrazinamide	5	1.3	1.3
Doxorubicin Hydrochloride	17	1.3	1.3
Mirabegron	20	1.3	1.3
Regorafenib	6	1.3	1.3
Entecavir	6	1.3	1.3
Rivastigmine	9	1.2	1.2
Nicotine	19	1.2	1.2
Methadone Hydrochloride	5	1.2	1.2
Selinexor	4	1.2	1.2
Oseltamivir Phosphate	11	1.1	1.1
Tiotropium Bromide Inhalation Spray	5	1.1	1.1
Romosozumab-Aqqg	6	1.1	1.1
Leuprolide Acetate	34	1.1	1.1
Imatinib Mesylate	12	1.1	1.1
Cariprazine	4	1.1	1.1
Minoxidil Foam 5% (Womens)	14	1.1	1.1
Ranitidine	83	1.1	1.1
Axicabtagene Ciloleucel	4	1.0	1.0
Encorafenib	4	1.0	1.0
Insulin Lispro	55	1.0	1.0
Clozapine	49	1.0	1.0
Tofacitinib Citrate	5	1.0	1.0
Ribavirin	24	0.9	0.9
Emtricitabine And Tenofovir Disoproxil Fumarate	17	0.9	0.9
Faricimab	3	0.9	0.9
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	3	0.9	0.9
Venetoclax	22	0.9	0.9
Ado-Trastuzumab Emtansine	3	0.9	0.9
Travoprost	3	0.9	0.9
Lenalidomide	146	0.9	0.9
Nicotine Polacrilex	13	0.9	0.9
Fentanyl Citrate	6	0.8	0.8
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	3	0.8	0.8
Sacubitril And Valsartan	38	0.8	0.8
Liraglutide	16	0.8	0.8
Crizotinib	4	0.8	0.8
Ustekinumab	32	0.8	0.8
Minoxidil	14	0.8	0.8
Pomalidomide	32	0.8	0.8
Tenofovir Disoproxil Fumarate	10	0.8	0.8
Abemaciclib	6	0.8	0.8
Remdesivir	4	0.8	0.8
Benralizumab	6	0.8	0.8
Evolocumab	47	0.7	0.7
Alirocumab	7	0.7	0.7
Ofatumumab	9	0.7	0.7
Orlistat	7	0.7	0.7
Canagliflozin	8	0.7	0.7
Exenatide	14	0.7	0.7
Sevelamer Carbonate	3	0.7	0.7
Ledipasvir And Sofosbuvir	5	0.7	0.7
Paliperidone	6	0.7	0.7
Hydrocodone Bitartrate	11	0.6	0.6
Cortisone Acetate	3	0.6	0.6
Esketamine Hydrochloride	4	0.6	0.6
Dulaglutide	19	0.5	0.5
Pirfenidone	8	0.5	0.5
Pegfilgrastim	19	0.5	0.5
Nirmatrelvir And Ritonavir	10	0.5	0.5
Guselkumab	5	0.4	0.4
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	4	0.3	0.3
Cinacalcet Hydrochloride	6	0.3	0.3
Salicylic Acid	3	0.1	0.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.