Reaction

Hypovolaemia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,771 reports · 478 co-occurring drugs

As of the last recalculation, Hypovolaemia appears in 5,771 FAERS reports alongside 478 co-occurring drug terms. The strongest observed disproportionality signal is QUININE (PRR 19.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Quinine	45	19.1	19.2
Eplerenone	66	18.8	18.9
Metolazone	57	18.5	18.6
Chlorhexidine Gluconate	36	14.3	14.3
Tranexamic Acid	34	13.9	13.9
Cefazolin Sodium	44	13.3	13.3
Linagliptin	64	12.8	12.8
Empagliflozin	224	12.4	12.5
Norepinephrine Bitartrate	49	12.4	12.4
Rocuronium Bromide	40	12.3	12.4
Indapamide	59	12.0	12.0
Insulin Glargine-Yfgn	68	11.3	11.4
Hydrocortisone Sodium Succinate	28	10.8	10.8
Propofol	105	10.5	10.6
Terazosin Hydrochloride	25	10.2	10.2
Atropine	23	10.0	10.1
Digoxin	189	9.8	9.8
Atropine Sulfate	29	9.7	9.7
Diphenoxylate Hydrochloride And Atropine Sulfate	36	9.5	9.6
Cholestyramine	31	9.3	9.3
Spironolactone	342	9.3	9.3
Furosemide	884	9.2	9.2
Bumetanide	65	9.0	9.0
Bupivacaine	23	8.9	8.9
Lisinopril And Hydrochlorothiazide Tablets	19	8.7	8.8
Sodium Bicarbonate	55	8.6	8.6
Sodium Bicarbonate Injection,	55	8.6	8.6
Losartan Potassium And Hydrochlorothiazide	27	8.4	8.4
Isosorbide Mononitrate	48	8.4	8.4
Lithium Carbonate	39	8.3	8.3
Daspone	22	8.2	8.2
Dapsone Gel, 5%	22	8.2	8.2
Torsemide	74	8.1	8.2
Dextrose	29	8.0	8.0
Potassium Chloride, Dextrose Monohydrate	196	7.9	7.9
Potassium Chloride Oral	196	7.9	7.9
Potassium Chloride Extended-Release	196	7.9	7.9
Dextrose Monohydrate	29	7.9	7.9
Enalapril Maleate	53	7.8	7.8
Basiliximab	25	7.7	7.7
Potassium Chloride	232	7.6	7.6
Fondaparinux Sodium	17	7.6	7.6
Cefazolin	19	7.5	7.5
Dalteparin Sodium	22	7.5	7.5
Dapsone	22	7.5	7.5
Lisinopril And Hydrochlorothiazide	21	7.4	7.4
Nitroglycerin	107	7.3	7.3
Ferrous Sulfate	100	7.3	7.3
Hydrochlorothiazide	279	7.2	7.2
Promethazine Hydrochloride	37	7.2	7.2
Docusate Sodium - Sennosides	63	7.1	7.1
Midazolam Hydrochloride	52	7.0	7.0
Gemfibrozil	29	6.9	6.9
Standardized Senna Concentrate	24	6.9	6.9
Olmesartan Medoxomil	68	6.9	6.9
Ascorbic Acid	44	6.9	6.9
Cisplatin	143	6.7	6.8
Epoetin Alfa	22	6.7	6.7
Metformin Hydrochloride Tablets	105	6.7	6.7
Metformin Hydrochloride Extended-Release Tablets	105	6.7	6.7
Metformin Hydrochloride Tablet	105	6.7	6.7
Irbesartan	82	6.7	6.7
Canagliflozin	55	6.7	6.7
Leucovorin Calcium	35	6.6	6.6
Midazolam	46	6.6	6.6
Calcium Gluconate	22	6.6	6.6
Metformin Hydrochloride	106	6.6	6.6
Nystatin Ointment	47	6.5	6.5
Nystatin Cream	47	6.5	6.5
Diltiazem Hydrochloride Extended-Release Tablets	20	6.4	6.4
Enalapril	96	6.3	6.3
Nystatin	47	6.2	6.3
Metformin	566	6.2	6.2
Antacid	80	6.1	6.2
Candesartan	60	6.1	6.1
Gentamicin	22	6.1	6.1
Colchicine	44	6.1	6.1
Metformin Er 500 Mg	469	6.0	6.0
Metformin Er 750 Mg	469	6.0	6.0
Cefuroxime	19	6.0	6.0
Vancomycin Hydrochloride	108	6.0	6.0
Diltiazem Hydrochloride	57	6.0	6.0
Phytonadione	14	6.0	6.0
Fentanyl Citrate	29	5.9	5.9
Candesartan Cilexetil	42	5.8	5.8
Carvedilol	207	5.7	5.7
Lisinopril	448	5.6	5.6
Insulin	86	5.6	5.6
Prochlorperazine	43	5.6	5.6
Cefepime Hydrochloride	25	5.6	5.6
Clarithromycin	53	5.6	5.6
Anastrozole Tablets	33	5.6	5.6
Docusate Sodium	88	5.6	5.6
Cefepime	22	5.6	5.6
Loperamide Hydrochloride And Dimethicone	49	5.6	5.6
Thiamine Hydrochloride	19	5.5	5.5
Lithium	38	5.5	5.5
Lithium Bromatum	38	5.5	5.5
Morphine	111	5.5	5.5
Dapagliflozin	47	5.4	5.4
Temazepam	56	5.4	5.4
Bisacodyl	21	5.4	5.4
Dronabinol	12	5.4	5.4
Magnesium Hydroxide	20	5.4	5.4
Loperamide Hcl	19	5.3	5.3
Ramipril	178	5.3	5.3
Bisacodyl Suppositories	19	5.3	5.3
Calcium Carbonate	97	5.3	5.3
Biscodyl	19	5.3	5.3
Tolvaptan	21	5.2	5.2
Sennosides 8.6 Mg Tablets	30	5.2	5.2
Senna	30	5.2	5.2
Hyoscyamine Sulfate	13	5.1	5.1
Vancomycin	81	5.1	5.1
Sodium Chloride	110	5.1	5.1
Metoroprolol Tartrate	92	5.1	5.1
Gentamicin Sulfate	22	5.0	5.0
Quinapril Hydrochloride	11	5.0	5.0
Senna Leaf	32	5.0	5.0
Budesonide	81	5.0	5.0
Clindamycin	39	5.0	5.0
Captopril	13	4.9	4.9
Loperamide Hydrochloride	60	4.9	4.9
Alendronate Sodium	134	4.9	4.9
Enoxaparin Sodium	77	4.9	4.9
Sodium Chloride Tablet	98	4.9	4.9
Sodium Chloride Tablets	98	4.9	4.9
Sennosides	40	4.9	4.9
Mesna Injection	11	4.8	4.8
Risedronate Sodium	41	4.8	4.8
Irinotecan Hydrochloride	17	4.8	4.8
Carisoprodol	25	4.7	4.7
Heparin Sodium	18	4.7	4.7
Mesna	11	4.7	4.7
Mycophenilic Acid	27	4.7	4.7
Fluorouracil Cream, 0.5%	98	4.7	4.7
Isosorbide Dinitrate	25	4.6	4.6
Fluorouracil	98	4.6	4.6
Warfarin Sodium	59	4.6	4.6
Piperacillin Sodium And Tazobactam Sodium	25	4.6	4.6
Nifedipine	59	4.5	4.5
Lactulose	48	4.5	4.5
Metoprolol Tartrate	328	4.5	4.5
Meclizine Hcl 12.5Mg	17	4.5	4.5
Meclizine Hcl 25Mg	17	4.5	4.5
Meclizine Hcl 12.5 Mg	17	4.5	4.5
Meclizine Hcl 25 Mg	17	4.5	4.5
Granisetron Hydrochloride	13	4.5	4.5
Fosaprepitant Dimeglumine	17	4.5	4.5
Sulfamethoxazole And Trimethoprim	103	4.5	4.5
Clindamycin Phosphate	41	4.5	4.5
Tretinoin	10	4.4	4.5
Felodipine Extended-Release Tablets	14	4.4	4.4
Felodipine	14	4.4	4.4
Magnesium Oxide	51	4.4	4.4
Bisoprolol Fumarate	163	4.4	4.4
Mycophenolic Acid	39	4.4	4.4
Norepinephrine	13	4.4	4.4
Desloratadine	13	4.4	4.4
Sitagliptin	86	4.4	4.4
Polyethylene Glycol	13	4.3	4.3
Erlotinib Hydrochloride	15	4.3	4.3
Meperidine Hydrochloride	11	4.3	4.3
Amlodipine Besylate And Benazepril Hydrochloride	11	4.3	4.3
Metoprolol	288	4.2	4.2
Aspirin 325 Mg	557	4.2	4.2
Aspirin 81 Mg	557	4.2	4.2
Ezetimibe	87	4.2	4.2
Carboplatin	146	4.2	4.2
Atenolol	153	4.2	4.2
Acetylcysteine	11	4.2	4.2
Aspirin	580	4.2	4.2
Meclizine	19	4.2	4.2
Cephalexin	25	4.2	4.2
Allopurinol	177	4.2	4.2
Metronidazole	73	4.2	4.2
Metoclopramide Hydrochloride	88	4.2	4.2
Calcitriol Capsules 0.25 Mcg	23	4.2	4.2
Calcitriol Capsules 0.5 Mcg	23	4.2	4.2
Valganciclovir Hydrochloride Powder,	14	4.1	4.2
Sotalol Hydrochloride	19	4.1	4.1
Calcitriol	23	4.1	4.1
Ganciclovir Sodium	12	4.1	4.1
Valsartan Oral	61	4.1	4.1
Warfarin	141	4.1	4.1
Chlorthalidone	13	4.0	4.0
Ezetimibe And Simvastatin	17	4.0	4.0
Valsartan	116	4.0	4.0
Dabigatran Etexilate	86	4.0	4.0
Valganciclovir	21	4.0	4.0
Valganciclovir Hydrochloride	21	4.0	4.0
Doxazosin Mesylate	40	4.0	4.0
Ondansetron Hydrochloride	134	4.0	4.0
0Xygen	54	4.0	4.0
Oxygen	54	4.0	4.0
Clonidine	56	4.0	4.0
Ipratropium Bromide	39	4.0	4.0
Metformin Hcl	60	3.9	3.9
Fentanyl	106	3.9	3.9
Aprepitant	20	3.9	3.9
Sevoflurane	9	3.9	3.9
Tobramycin Solution	13	3.9	3.9
Diphenhydramine Hcl	12	3.9	3.9
Loperamide Hydrochloride Oral	11	3.9	3.9
Ganciclovir	11	3.9	3.9
Meclizine Hydrochloride	21	3.9	3.9
Metoprolol Tartrate Injection	198	3.9	3.9
Bleomycin Sulfate	11	3.8	3.8
Indomethacin	14	3.8	3.8
Tobramycin Sulfate	13	3.8	3.8
Mirtazapine	95	3.8	3.8
Simvastatin	254	3.8	3.8
Famotidine	121	3.8	3.8
Doxorubicin Hydrochloride	34	3.8	3.8
Tenofovir Disoproxil Fumarate Tablets	9	3.8	3.8
Lorazepam	183	3.8	3.8
Melphalan Hydrochloride	26	3.8	3.8
Glyburide	25	3.7	3.7
Valsartan And Hydrochlorothiazide	14	3.7	3.7
Zolpidem Tartrate	137	3.7	3.7
Erythropoietin	21	3.7	3.7
Insulin Aspart	67	3.7	3.7
Tacrolimus	156	3.7	3.7
Albuterol	120	3.7	3.7
Metoprolol Succinate	87	3.7	3.7
Melphalan	23	3.7	3.7
Anastrozole	37	3.7	3.7
Ciprofloxacin Hydrochloride And Hydrocortisone	21	3.7	3.7
Ondansetron	109	3.6	3.7
Ondansetron Tablets	109	3.6	3.6
Docusate Sodium 100Mg	24	3.6	3.6
Doxazosin	28	3.6	3.6
Magnesium Sulfate Heptahydrate	13	3.6	3.6
Magnesium Sulfate	13	3.6	3.6
Epoprostenol	13	3.6	3.6
Vincristine Sulfate	29	3.6	3.6
Alemtuzumab	19	3.6	3.6
Metoprolol Succinate Er Tablets	61	3.5	3.6
Ciprofloxacin	89	3.5	3.5
Labetalol	13	3.5	3.5
Capecitabine	88	3.5	3.5
Ciprofolxacin	69	3.5	3.5
Metoclopramide	53	3.5	3.5
Ciprofloxacin Tablets	69	3.5	3.5
Theophylline Anhydrous	12	3.5	3.5
Teduglutide	13	3.5	3.5
Iohexol	8	3.5	3.5
Fluconazole	67	3.5	3.5
Sucralfate	23	3.5	3.5
Cetuximab	30	3.5	3.5
Amlodipine	251	3.5	3.5
Theophylline	11	3.5	3.5
Pantoprazole	235	3.4	3.5
Granisetron	10	3.4	3.4
Darbepoetin Alfa	51	3.4	3.4
Octreotide Acetate	29	3.4	3.4
Losartan Potassium	74	3.4	3.4
Tizanidine Hydrochloride	17	3.4	3.4
Magnesium Sulfate In Water For	12	3.4	3.4
Pantoprazole Sodium	137	3.4	3.4
Cytarabine	56	3.4	3.4
Tacrolimus Ointment 0.1%	115	3.4	3.4
Cimetidine	9	3.4	3.4
Tacrolimus Extended-Release Capsules	115	3.4	3.4
Amlodipine Besylate	134	3.4	3.4
Ciprofloxacin Hydrochloride	89	3.3	3.3
Ketoprofen	12	3.3	3.3
Psyllium Husk	9	3.3	3.3
Pegaspargase	11	3.2	3.2
Tolterodine Tartrate	8	3.2	3.2
Mupirocin	12	3.2	3.2
Olanzapine Pamoate	36	3.2	3.2
Sitagliptin And Metformin Hydrochloride	19	3.2	3.2
Acetaminophen Tablet Extended Release	218	3.2	3.2
Pain Reliever	218	3.2	3.2
Acetaminophen 500Mg	218	3.2	3.2
Atorvastatin Calcium, Film Coated	61	3.2	3.2
Donepezil Hydrochloride	32	3.2	3.2
Mupirocin Calcium	12	3.2	3.2
Isoniazid	14	3.1	3.1
Ranolazine	9	3.1	3.1
Niacin	10	3.1	3.1
Fluticasone Propionate Nasal	26	3.1	3.1
Paclitaxel (Aibumin-Bound)	70	3.1	3.1
Mycophenolate Mofetil	115	3.1	3.1
Mycophenolate Mofetil Hydrochloride	115	3.1	3.1
Olanzapine	91	3.1	3.1
Etoposide	62	3.1	3.1
Adrenalinum	35	3.1	3.1
Amoxicillin	64	3.0	3.0
Glipizide	51	3.0	3.0
Amantadine	13	3.0	3.0
Atorvastatin Calcium	203	3.0	3.0
Extended Phenytoin Sodium	14	3.0	3.0
Filgrastim	31	3.0	3.0
Ribociclib	26	3.0	3.0
Paclitaxel	81	3.0	3.0
Glimepiride	32	3.0	3.0
Misoprostol	8	3.0	3.0
Fenofibrate	29	3.0	3.0
Dabigatran Etexilate Mesylate	59	2.9	3.0
Sirolimus	11	2.9	3.0
Buspirone Hydrochloride	9	2.9	2.9
Salmeterol Xinafoate	7	2.9	2.9
Docetaxel Anhydrous	54	2.9	2.9
Docetaxel	54	2.9	2.9
Amiodarone Hydrochloride	9	2.9	2.9
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	40	2.9	2.9
Human Insulin	10	2.9	2.9
Alteplase	12	2.9	2.9
Escitslopram	46	2.9	2.9
Piperacillin Sodium,Tazobactam Sodium	21	2.9	2.9
Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	7	2.9	2.9
Nitrofurantoin	13	2.8	2.8
Pioglitazone	34	2.8	2.8
Raltegravir	13	2.8	2.8
Oxaliplatin	58	2.8	2.8
Nitrofurantoin (Monohydrate/Macrocrystals)	13	2.8	2.8
Bendamustine Hcl	12	2.8	2.8
Escitalopram Oxalate	56	2.8	2.8
Macitentan	53	2.8	2.8
Lansoprazole	135	2.8	2.8
Escitalopram	106	2.8	2.8
Ceftriaxone	25	2.8	2.8
Dofetilide	8	2.7	2.8
Prochlorperazine Maleate	7	2.7	2.7
Ceftriaxone Sodium	29	2.7	2.7
Metronidazole Topical	36	2.7	2.7
Hydroxyzine	36	2.7	2.7
Alendronate Sodium Tablet	14	2.7	2.7
Oxycodone And Acetaminophen Tablets	9	2.7	2.7
Loratadine And Pseudoephedrine Sulfate	6	2.7	2.7
Bendamustine Hydrochloride	9	2.7	2.7
Dexamethasone 1.5 Mg	215	2.7	2.7
Doxorubicin	66	2.7	2.7
Atovaquone	6	2.7	2.7
Dexamethasone	216	2.7	2.7
Modafinil	24	2.7	2.7
Clopidogrel	145	2.7	2.7
Gemcitabine Hydrochloride	39	2.7	2.7
Iron Sucrose	7	2.7	2.7
Darunavir	11	2.6	2.6
Venlafaxine Hydrochloride	95	2.6	2.6
Amlodipine Besylate And Valsartan	8	2.6	2.6
Erlotinib	7	2.6	2.6
Insulin Glargine	175	2.6	2.6
Bupropion	32	2.6	2.6
Melatonin	39	2.6	2.6
Oxybutynin	21	2.6	2.6
Everolimus Tablets	12	2.6	2.6
Citalopram	97	2.6	2.6
Venlafaxine	51	2.6	2.6
Paricalcitol	10	2.6	2.6
Insulin Human	28	2.5	2.5
Lovastatin	18	2.5	2.5
Travoprost	6	2.5	2.5
Rifampicin	7	2.5	2.5
Gemcitabine	27	2.5	2.5
Meropenem	22	2.5	2.5
Rifampin	10	2.5	2.5
Pemetrexed Disodium	26	2.5	2.5
Bevacizumab	84	2.5	2.5
Oxycodone Hydrochloride And Acetaminophen	67	2.5	2.5
Deferasirox	18	2.5	2.5
Methadone	29	2.5	2.5
Polyethylene Glycol 3350	64	2.4	2.4
Alprazolam	136	2.4	2.4
Romiplostim	10	2.4	2.4
Duloxetine	46	2.4	2.4
Omeprazole Magnesium	287	2.4	2.4
Rosuvastatin	133	2.4	2.4
Trastuzumab	45	2.4	2.4
Acetaminophen And Codeine	8	2.4	2.4
Thalidomide	24	2.4	2.4
Sildenafil Powder,	23	2.3	2.3
Vortioxetine	11	2.3	2.3
Instalax Polyethylene Glycol 3350	8	2.3	2.3
Esomeprazole Magnesium	148	2.3	2.3
Propranolol Hydrochloride	46	2.3	2.3
Posaconazole Delayed-Release	7	2.3	2.3
Losartan	110	2.3	2.3
Leflunomide	66	2.3	2.3
Hydromorphone Hydrochloride	58	2.3	2.3
Dorzolamide Hydrochloride And Timolol Maleate	5	2.3	2.3
Polyethylene Glycol 400	8	2.3	2.3
Aripiprazole Oral	26	2.3	2.3
Aripiprazole Orally Disintegrating	26	2.3	2.3
Pertuzumab	17	2.3	2.3
Piperacillin And Tazobactam	8	2.3	2.3
Sacubitril And Valsartan	72	2.3	2.3
Cyclophosphamide Injection, Solution	109	2.2	2.2
Cyclophosphamide	109	2.2	2.2
Cyclophosphamide For Injection	109	2.2	2.2
Gabapentin	222	2.2	2.2
Multivitamin	31	2.2	2.2
Clopidogrel Bisulfate	63	2.2	2.2
Polatuzumab Vedotin	6	2.2	2.2
Apixaban	41	2.2	2.2
Epinephrine	40	2.2	2.2
Loratadine Oral	30	2.2	2.2
Sevelamer Carbonate	7	2.2	2.2
Pemetrexed	13	2.2	2.2
Remdesivir	8	2.2	2.2
Insulin Lispro	82	2.2	2.2
Bosentan	30	2.2	2.2
Bortezomib	53	2.1	2.1
Tafamidis	7	2.1	2.1
Guaifenesin	18	2.1	2.1
Micafungin Sodium	5	2.1	2.1
Tobramycin	14	2.1	2.1
Ritonavir	17	2.1	2.1
Selexipag	15	2.1	2.1
Lapatinib	9	2.1	2.1
Oral Semaglutide	42	2.1	2.1
Oxycodone	106	2.1	2.1
Sildenafil	33	2.1	2.1
Eszopiclone	14	2.0	2.0
Conjugated Estrogens	32	2.0	2.0
Tenofovir Disoproxil Fumarate	18	2.0	2.0
Sildenafil Citrate	69	2.0	2.0
Agalsidase Beta	5	2.0	2.0
Estrogens, Conjugated	32	1.9	1.9
Imatinib Mesylate	15	1.9	1.9
Sunitinib Malate	21	1.9	1.9
Ticagrelor	17	1.9	1.9
Rivastigmine	10	1.9	1.9
Ribavirin	34	1.9	1.9
Sorafenib	11	1.9	1.9
Treprostinil	64	1.8	1.8
Ipilimumab	22	1.8	1.8
Rivaroxaban	103	1.8	1.8
Nicotine	20	1.8	1.8
Riociguat	16	1.8	1.8
Ziprasidone Mesylate	7	1.8	1.8
Dabrafenib	10	1.7	1.7
Liraglutide	23	1.7	1.7
Axitinib	9	1.7	1.7
Risperidone	61	1.7	1.7
Miconazole Nitrate	4	1.7	1.7
Trametinib	11	1.6	1.6
Panitumumab	7	1.6	1.6
Morphine Sulfate	53	1.6	1.6
Regorafenib	5	1.6	1.6
Sofosbuvir	8	1.5	1.5
Carbidopa And Levodopa	19	1.4	1.4
Exenatide	21	1.4	1.4
Fam-Trastuzumab Deruxtecan-Nxki	4	1.4	1.4
Brentuximab Vedotin	4	1.4	1.4
Carfilzomib	11	1.4	1.4
Azacitidine For	7	1.4	1.4
Bimatoprost	11	1.4	1.4
Trifluridine And Tipiracil	4	1.3	1.3
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose	3	1.3	1.3
Nivolumab	35	1.3	1.3
Oxycodone Hydrochloride	78	1.3	1.3
Hydrocodone Bitartrate	15	1.2	1.2
Alpelisib	3	1.2	1.2
Rucaparib	3	1.2	1.2
Vemurafenib	4	1.2	1.2
Temozolomide	7	1.2	1.2
Acalabrutinib	4	1.2	1.2
Ruxolitinib	23	1.2	1.2
Crizotinib	4	1.1	1.1
Ixazomib	9	1.1	1.1
Axicabtagene Ciloleucel	3	1.1	1.1
Peginterferon Alfa-2A	16	1.1	1.1
Ethyl Alcohol	8	1.1	1.1
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride	9	1.0	1.0
Tirzepatide	46	1.0	1.0
Glecaprevir And Pibrentasvir	3	1.0	1.0
Ambrisentan	34	1.0	1.0
Dulaglutide	24	1.0	1.0
Cinacalcet Hydrochloride	12	0.9	0.9
Durvalumab	5	0.9	0.9
Tapentadol Hydrochloride	8	0.9	0.9
Pegfilgrastim	23	0.8	0.8
Lenalidomide	90	0.8	0.8
Salicylic Acid	3	0.2	0.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.